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E1V7Q5

- E1V7Q5_HALED

UniProt

E1V7Q5 - E1V7Q5_HALED

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Protein
Alanine racemase
Gene
dadX, HELO_3609
Organism
Halomonas elongata (strain ATCC 33173 / DSM 2581 / NBRC 15536 / NCIMB 2198 / 1H9)
Status
Unreviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotations

Cofactori

Pyridoxal phosphate By similarity.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei35 – 351Proton acceptor; specific for D-alanine By similarityUniRule annotation
Binding sitei131 – 1311Substrate By similarityUniRule annotation
Active sitei256 – 2561Proton acceptor; specific for L-alanine By similarityUniRule annotation
Binding sitei304 – 3041Substrate; via amide nitrogen By similarityUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciHELO768066:GJEE-2677-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Name:dadXImported
Ordered Locus Names:HELO_3609Imported
OrganismiHalomonas elongata (strain ATCC 33173 / DSM 2581 / NBRC 15536 / NCIMB 2198 / 1H9)Imported
Taxonomic identifieri768066 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaOceanospirillalesHalomonadaceaeHalomonas
ProteomesiUP000008707: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei35 – 351N6-(pyridoxal phosphate)lysine By similarityUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliE1V7Q5.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000031446.
KOiK01775.
OMAiYGHGLER.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E1V7Q5-1 [UniParc]FASTAAdd to Basket

« Hide

MARPLRADID LDALCHNYRL ARDLAPTSRS LAVLKADAYG HGLVPCARAL    50
EGLAPAFAVA CLEEAEALRE GGITAPIVLL EGIFSADELA RVEALKLGTV 100
VHSDWQVEAL LSHRPAEPIP TWVKVDSGMH RLGFAPERAA SVWARLSAAP 150
AQACDLHLMS HFATADHADT AYFEHQMRTL NALAETLNAP TCLANSPATL 200
ARPESHGAWN RPGVMLYGSD PLEASNSASR ELEPVMTLRS QLIAVRDLDE 250
GEPVGYGGRW RAPRPSRIGV VACGYGDGYD RHAIDGTPAL VAGRRTTLVG 300
KVSMDMLTVD LTDIPEADIG SEVVLWGRAA NGEVLSVDEV ARHCDTISYT 350
LLTGVLPRVP RRYHSG 366
Length:366
Mass (Da):39,342
Last modified:November 30, 2010 - v1
Checksum:i65C9103CEFFC0470
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FN869568 Genomic DNA. Translation: CBV43493.1.
RefSeqiWP_013333365.1. NC_014532.1.
YP_003898678.1. NC_014532.1.

Genome annotation databases

EnsemblBacteriaiCBV43493; CBV43493; HELO_3609.
GeneIDi9747860.
KEGGihel:HELO_3609.
PATRICi42356781. VBIHalElo161731_2804.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FN869568 Genomic DNA. Translation: CBV43493.1 .
RefSeqi WP_013333365.1. NC_014532.1.
YP_003898678.1. NC_014532.1.

3D structure databases

ProteinModelPortali E1V7Q5.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CBV43493 ; CBV43493 ; HELO_3609 .
GeneIDi 9747860.
KEGGi hel:HELO_3609.
PATRICi 42356781. VBIHalElo161731_2804.

Phylogenomic databases

HOGENOMi HOG000031446.
KOi K01775.
OMAi YGHGLER.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci HELO768066:GJEE-2677-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "A blueprint of ectoine metabolism from the genome of the industrial producer Halomonas elongata DSM 2581(T)."
    Schwibbert K., Marin-Sanguino A., Bagyan I., Heidrich G., Lentzen G., Seitz H., Rampp M., Schuster S.C., Klenk H.P., Pfeiffer F., Oesterhelt D., Kunte H.J.
    Environ. Microbiol. 13:1973-1994(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33173 / DSM 2581 / NBRC 15536 / NCIMB 2198 / 1H9.

Entry informationi

Entry nameiE1V7Q5_HALED
AccessioniPrimary (citable) accession number: E1V7Q5
Entry historyi
Integrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: September 3, 2014
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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