Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

E1V7Q5

- E1V7Q5_HALED

UniProt

E1V7Q5 - E1V7Q5_HALED

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Alanine racemase

Gene

dadX

Organism
Halomonas elongata (strain ATCC 33173 / DSM 2581 / NBRC 15536 / NCIMB 2198 / 1H9)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotation

Cofactori

Note: Pyridoxal phosphate.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei35 – 351Proton acceptor; specific for D-alanineUniRule annotation
Binding sitei131 – 1311SubstrateUniRule annotation
Active sitei256 – 2561Proton acceptor; specific for L-alanineUniRule annotation
Binding sitei304 – 3041Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciHELO768066:GJEE-2677-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Name:dadXImported
Ordered Locus Names:HELO_3609Imported
OrganismiHalomonas elongata (strain ATCC 33173 / DSM 2581 / NBRC 15536 / NCIMB 2198 / 1H9)Imported
Taxonomic identifieri768066 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaOceanospirillalesHalomonadaceaeHalomonas
ProteomesiUP000008707: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei35 – 351N6-(pyridoxal phosphate)lysineUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliE1V7Q5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000031446.
KOiK01775.
OMAiYGHGLER.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E1V7Q5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MARPLRADID LDALCHNYRL ARDLAPTSRS LAVLKADAYG HGLVPCARAL
60 70 80 90 100
EGLAPAFAVA CLEEAEALRE GGITAPIVLL EGIFSADELA RVEALKLGTV
110 120 130 140 150
VHSDWQVEAL LSHRPAEPIP TWVKVDSGMH RLGFAPERAA SVWARLSAAP
160 170 180 190 200
AQACDLHLMS HFATADHADT AYFEHQMRTL NALAETLNAP TCLANSPATL
210 220 230 240 250
ARPESHGAWN RPGVMLYGSD PLEASNSASR ELEPVMTLRS QLIAVRDLDE
260 270 280 290 300
GEPVGYGGRW RAPRPSRIGV VACGYGDGYD RHAIDGTPAL VAGRRTTLVG
310 320 330 340 350
KVSMDMLTVD LTDIPEADIG SEVVLWGRAA NGEVLSVDEV ARHCDTISYT
360
LLTGVLPRVP RRYHSG
Length:366
Mass (Da):39,342
Last modified:November 30, 2010 - v1
Checksum:i65C9103CEFFC0470
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN869568 Genomic DNA. Translation: CBV43493.1.
RefSeqiWP_013333365.1. NC_014532.1.
YP_003898678.1. NC_014532.1.

Genome annotation databases

EnsemblBacteriaiCBV43493; CBV43493; HELO_3609.
GeneIDi9747860.
KEGGihel:HELO_3609.
PATRICi42356781. VBIHalElo161731_2804.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN869568 Genomic DNA. Translation: CBV43493.1 .
RefSeqi WP_013333365.1. NC_014532.1.
YP_003898678.1. NC_014532.1.

3D structure databases

ProteinModelPortali E1V7Q5.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CBV43493 ; CBV43493 ; HELO_3609 .
GeneIDi 9747860.
KEGGi hel:HELO_3609.
PATRICi 42356781. VBIHalElo161731_2804.

Phylogenomic databases

HOGENOMi HOG000031446.
KOi K01775.
OMAi YGHGLER.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci HELO768066:GJEE-2677-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "A blueprint of ectoine metabolism from the genome of the industrial producer Halomonas elongata DSM 2581(T)."
    Schwibbert K., Marin-Sanguino A., Bagyan I., Heidrich G., Lentzen G., Seitz H., Rampp M., Schuster S.C., Klenk H.P., Pfeiffer F., Oesterhelt D., Kunte H.J.
    Environ. Microbiol. 13:1973-1994(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33173 / DSM 2581 / NBRC 15536 / NCIMB 2198 / 1H9Imported.

Entry informationi

Entry nameiE1V7Q5_HALED
AccessioniPrimary (citable) accession number: E1V7Q5
Entry historyi
Integrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: November 26, 2014
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3