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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Halomonas elongata (strain ATCC 33173 / DSM 2581 / NBRC 15536 / NCIMB 2198 / 1H9)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei141UniRule annotation1
Active sitei546UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotationImported
Biological processCarbon dioxide fixationUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciHELO768066:G1GVR-2216-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:HELO_3010Imported
OrganismiHalomonas elongata (strain ATCC 33173 / DSM 2581 / NBRC 15536 / NCIMB 2198 / 1H9)Imported
Taxonomic identifieri768066 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaOceanospirillalesHalomonadaceaeHalomonas
Proteomesi
  • UP000008707 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi768066.HELO_3010

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CCA Bacteria
COG2352 LUCA
HOGENOMiHOG000238648
KOiK01595
OMAiPWVFGWT
OrthoDBiPOG091H040O

Family and domain databases

HAMAPiMF_00595 PEPcase_type1, 1 hit
InterProiView protein in InterPro
IPR021135 PEP_COase
IPR022805 PEP_COase_bac/pln-type
IPR018129 PEP_COase_Lys_AS
IPR033129 PEPCASE_His_AS
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
PANTHERiPTHR30523 PTHR30523, 1 hit
PfamiView protein in Pfam
PF00311 PEPcase, 1 hit
PRINTSiPR00150 PEPCARBXLASE
SUPFAMiSSF51621 SSF51621, 1 hit
PROSITEiView protein in PROSITE
PS00781 PEPCASE_1, 1 hit
PS00393 PEPCASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

E1V4F6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSHDLHESLR DNVRILGDSL GRTIADDLGQ GFVDRIETIR GLAKRGRQGE
60 70 80 90 100
ADGRRELIEY LRQLPDSELL PVTRAFNQFL NLANIAEQHY RARFRRVEDY
110 120 130 140 150
KPGSQPALGE LLERARGEGH SPRKLVESLA NMRVELVLTA HPTEVIRRTL
160 170 180 190 200
IQKYDAIDDC LTAIESSADY PERGARAKGR LEELIGQAWH TDEIRHERPT
210 220 230 240 250
PVDEAKWGFA VIENSLWQAV PDFHRDLDNL LLDTAGERLP LDAAPIRFAS
260 270 280 290 300
WMGGDRDGNP NVTSKVTREV LLLGRWMAAD LYLRDLDQLK TELSMWKANS
310 320 330 340 350
ALRAEVGDVA EPYRELLKRL LARVEATRDW AKAQLDGKSY DGGPIIETRD
360 370 380 390 400
QLYAPLLTCY RSLCDVGLDT IANGVLLDTL RRVAVFGVTL TKLDLRQEAG
410 420 430 440 450
RHEQVMEELT DGLGLGHYRE WDEEQRQEFL LAELASRRPL IPRRWECSAE
460 470 480 490 500
SREVLDTFQV AAGEHAEALG TYIISMAAQP SDVLAVALLM KEVGGDARLP
510 520 530 540 550
IAPLFETLDD LNRAGDVIDR LLALPGYREL TGDRQEVMIG YSDSAKDAGQ
560 570 580 590 600
LAAAWAQYRA QEALVEVCRH HGVYLTLFHG RGGTVGRGGG PAHAAILSQP
610 620 630 640 650
PGSVNGSLRV TEQGEMIRFK FGQPEIALRS MEIYACAVLE ASLLPPPTPE
660 670 680 690 700
PAWREEMDRL AEVAHGTYVS VVREDPDFVP YFRSVTPESA LGRLPLGSRP
710 720 730 740 750
AKRRQDGGVE TLRAIPWIFA WTQTRLMLPA WLGSGEAFAK RLEDEGGLEV
760 770 780 790 800
LRDMRDRWPF FGTYLEMLEM LLAKADVSIA AYYEHRLVDE PALEALGQRL
810 820 830 840 850
RERFGRLHQV VLEILDQQEL LENTPLIRQA VEVRNPYIDP LHGLQAELLQ
860 870 880
RNRDADGAIS ADLSRALMVT MAGIAAGLRN TG
Length:882
Mass (Da):98,789
Last modified:November 30, 2010 - v1
Checksum:i2326874EEADEDA04
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN869568 Genomic DNA Translation: CBV42894.1

Genome annotation databases

EnsemblBacteriaiCBV42894; CBV42894; HELO_3010
KEGGihel:HELO_3010

Similar proteinsi

Entry informationi

Entry nameiE1V4F6_HALED
AccessioniPrimary (citable) accession number: E1V4F6
Entry historyiIntegrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: March 28, 2018
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health