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E1UKV8 (E1UKV8_BACAS) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length393 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. RuleBase RU004247 HAMAP-Rule MF_01201 SAAS SAAS020622

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS020622

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site391Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2721Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1391Substrate By similarity HAMAP-Rule MF_01201
Binding site3201Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue391N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
E1UKV8 [UniParc].

Last modified November 30, 2010. Version 1.
Checksum: BE465A1178641C16

FASTA39343,305
        10         20         30         40         50         60 
MKKLCREVWI EVDLDAIKKN IRAIRRHIPN KSKIMAVVKA NAYGHGSVEV ARQALESGAS 

        70         80         90        100        110        120 
ELAVASVEEG IVLRRAGITA PILVLGFTAL SCVKKSAVWN ITLSAFQVSW IKKANQILEE 

       130        140        150        160        170        180 
EAVSKRLSIH INVDTGMGRL GVRTEKDLLA VVKALKSSTY LSWDGIFTHF STADEPDTEL 

       190        200        210        220        230        240 
TMLQHEKFIS FLRFLKDQGI TLPTVHMCNT AAAIAFPEFS ADMIRLGIGL YGLYPSAYIK 

       250        260        270        280        290        300 
ELDLVKLTPA LSLKARIAYV KAMVTEPRTV SYGATYIAEP GEIIATIPIG YADGYSRALS 

       310        320        330        340        350        360 
NRGFILYRGR RVPVAGRVTM DMIMVSLGES EGKQGEEVVI YGKQKGAEIS VDEIAEMLGT 

       370        380        390 
INYEVVSTLS RRVPRFYIRD GEIIKVSAPV LYV 

« Hide

References

« Hide 'large scale' references
[1]"Relationship of Bacillus amyloliquefaciens clades associated with strains DSM7T and FZB42: a proposal for Bacillus amyloliquefaciens subsp. amyloliquefaciens subsp. nov. and Bacillus amyloliquefaciens subsp. plantarum subsp. nov. based on their discriminating complete genome sequences."
Borriss R., Chen X., Rueckert C., Blom J., Becker A., Baumgarth B., Fan B., Pukall R., Schumann P., Sproer C., Junge H., Vater J., Puhler A., Klenk H.P.
Int. J. Syst. Evol. Microbiol. 0:0-0(2010)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: DSM7.
[2]"Genome sequence of B. amyloliquefaciens type strain DSM7(T) reveals differences to plant-associated B. amyloliquefaciens FZB42."
Ruckert C., Blom J., Chen X., Reva O., Borriss R.
J. Biotechnol. 155:78-85(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 23350 / DSM 7 / BCRC 11601 / NBRC 15535 / NRRL B-14393.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
FN597644 Genomic DNA. Translation: CBI43451.1.
RefSeqYP_003920921.1. NC_014551.1.

3D structure databases

ProteinModelPortalE1UKV8.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCBI43451; CBI43451; BAMF_2325.
GeneID9779792.
KEGGbao:BAMF_2325.
PATRIC42473851. VBIBacAmy172706_2502.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000031444.
KOK01775.

Enzyme and pathway databases

BioCycBAMY692420:GHU2-2414-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE1UKV8_BACAS
AccessionPrimary (citable) accession number: E1UKV8
Entry history
Integrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: July 9, 2014
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)