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E1UKV8

- E1UKV8_BACAS

UniProt

E1UKV8 - E1UKV8_BACAS

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Protein

Alanine racemase

Gene
alrB, alr1, BAMF_2325
Organism
Bacillus amyloliquefaciens (strain ATCC 23350 / DSM 7 / BCRC 11601 / NBRC 15535 / NRRL B-14393)
Status
Unreviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotations

Cofactori

Pyridoxal phosphate By similarity.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei39 – 391Proton acceptor; specific for D-alanine By similarityUniRule annotation
Binding sitei139 – 1391Substrate By similarityUniRule annotation
Active sitei272 – 2721Proton acceptor; specific for L-alanine By similarityUniRule annotation
Binding sitei320 – 3201Substrate; via amide nitrogen By similarityUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciBAMY692420:GHU2-2414-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Name:alrBImported
Synonyms:alr1Imported
Ordered Locus Names:BAMF_2325Imported
OrganismiBacillus amyloliquefaciens (strain ATCC 23350 / DSM 7 / BCRC 11601 / NBRC 15535 / NRRL B-14393)Imported
Taxonomic identifieri692420 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
ProteomesiUP000006562: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei39 – 391N6-(pyridoxal phosphate)lysine By similarityUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliE1UKV8.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000031444.
KOiK01775.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E1UKV8-1 [UniParc]FASTAAdd to Basket

« Hide

MKKLCREVWI EVDLDAIKKN IRAIRRHIPN KSKIMAVVKA NAYGHGSVEV    50
ARQALESGAS ELAVASVEEG IVLRRAGITA PILVLGFTAL SCVKKSAVWN 100
ITLSAFQVSW IKKANQILEE EAVSKRLSIH INVDTGMGRL GVRTEKDLLA 150
VVKALKSSTY LSWDGIFTHF STADEPDTEL TMLQHEKFIS FLRFLKDQGI 200
TLPTVHMCNT AAAIAFPEFS ADMIRLGIGL YGLYPSAYIK ELDLVKLTPA 250
LSLKARIAYV KAMVTEPRTV SYGATYIAEP GEIIATIPIG YADGYSRALS 300
NRGFILYRGR RVPVAGRVTM DMIMVSLGES EGKQGEEVVI YGKQKGAEIS 350
VDEIAEMLGT INYEVVSTLS RRVPRFYIRD GEIIKVSAPV LYV 393
Length:393
Mass (Da):43,305
Last modified:November 30, 2010 - v1
Checksum:iBE465A1178641C16
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FN597644 Genomic DNA. Translation: CBI43451.1.
RefSeqiWP_013352824.1. NC_014551.1.
YP_003920921.1. NC_014551.1.

Genome annotation databases

EnsemblBacteriaiCBI43451; CBI43451; BAMF_2325.
GeneIDi9779792.
KEGGibao:BAMF_2325.
PATRICi42473851. VBIBacAmy172706_2502.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FN597644 Genomic DNA. Translation: CBI43451.1 .
RefSeqi WP_013352824.1. NC_014551.1.
YP_003920921.1. NC_014551.1.

3D structure databases

ProteinModelPortali E1UKV8.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CBI43451 ; CBI43451 ; BAMF_2325 .
GeneIDi 9779792.
KEGGi bao:BAMF_2325.
PATRICi 42473851. VBIBacAmy172706_2502.

Phylogenomic databases

HOGENOMi HOG000031444.
KOi K01775.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci BAMY692420:GHU2-2414-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Relationship of Bacillus amyloliquefaciens clades associated with strains DSM7T and FZB42: a proposal for Bacillus amyloliquefaciens subsp. amyloliquefaciens subsp. nov. and Bacillus amyloliquefaciens subsp. plantarum subsp. nov. based on their discriminating complete genome sequences."
    Borriss R., Chen X., Rueckert C., Blom J., Becker A., Baumgarth B., Fan B., Pukall R., Schumann P., Sproer C., Junge H., Vater J., Puhler A., Klenk H.P.
    Int. J. Syst. Evol. Microbiol. 0:0-0(2010)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: DSM7.
  2. "Genome sequence of B. amyloliquefaciens type strain DSM7(T) reveals differences to plant-associated B. amyloliquefaciens FZB42."
    Ruckert C., Blom J., Chen X., Reva O., Borriss R.
    J. Biotechnol. 155:78-85(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 23350 / DSM 7 / BCRC 11601 / NBRC 15535 / NRRL B-14393.

Entry informationi

Entry nameiE1UKV8_BACAS
AccessioniPrimary (citable) accession number: E1UKV8
Entry historyi
Integrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: September 3, 2014
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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