ID   E1T6R4_BURSG            Unreviewed;       422 AA.
AC   E1T6R4;
DT   30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2010, sequence version 1.
DT   27-MAR-2024, entry version 49.
DE   RecName: Full=alanine transaminase {ECO:0000256|ARBA:ARBA00026106};
DE            EC=2.6.1.2 {ECO:0000256|ARBA:ARBA00026106};
GN   OrderedLocusNames=BC1003_1519 {ECO:0000313|EMBL:ADN57490.1};
OS   Burkholderia sp. (strain CCGE1003).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia.
OX   NCBI_TaxID=640512 {ECO:0000313|EMBL:ADN57490.1};
RN   [1] {ECO:0000313|EMBL:ADN57490.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=CCGE1003 {ECO:0000313|EMBL:ADN57490.1};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA   Pitluck S., Daligault H., Davenport K., Detter J.C., Han C., Tapia R.,
RA   Land M., Hauser L., Jeffries C., Kyrpides N., Ivanova N., Ovchinnikova G.,
RA   Martinez-Romero E., Rogel M.A., Auchtung J., Tiedje J.M., Woyke T.;
RT   "Complete sequence of chromosome1 of Burkholderia sp. CCGE1003.";
RL   Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- SIMILARITY: Belongs to the class-I pyridoxal-phosphate-dependent
CC       aminotransferase family. {ECO:0000256|ARBA:ARBA00007441}.
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DR   EMBL; CP002217; ADN57490.1; -; Genomic_DNA.
DR   AlphaFoldDB; E1T6R4; -.
DR   STRING; 640512.BC1003_1519; -.
DR   KEGG; bgf:BC1003_1519; -.
DR   eggNOG; COG0436; Bacteria.
DR   HOGENOM; CLU_017584_4_2_4; -.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   CDD; cd00609; AAT_like; 1.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR004839; Aminotransferase_I/II.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   PANTHER; PTHR43488; GLUTAMATE-PYRUVATE AMINOTRANSFERASE ALAA; 1.
DR   PANTHER; PTHR43488:SF2; GLUTAMATE-PYRUVATE AMINOTRANSFERASE ALAA; 1.
DR   Pfam; PF00155; Aminotran_1_2; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   3: Inferred from homology;
KW   Aminotransferase {ECO:0000313|EMBL:ADN57490.1};
KW   Transferase {ECO:0000313|EMBL:ADN57490.1}.
FT   DOMAIN          45..401
FT                   /note="Aminotransferase class I/classII"
FT                   /evidence="ECO:0000259|Pfam:PF00155"
SQ   SEQUENCE   422 AA;  46916 MW;  C29872E352676553 CRC64;
     MPINQDEVPA VKPILKSNKL LNVCYDIRGP VLEHAKRLEE EGHRIIKLNI GNLAPFGFEA
     PDEIIQDMIL NLPGSSGYSD SKGVFAARKA IMHYTQQKGV HGVELDDIYI GNGASELIVM
     ALQGLLNDGD EVLLPAPDYP LWTAGVSLAG GTPVHYICDE SNRWMPDLDD IRAKITPNTR
     ALVVINPNNP TGALYSDELL LGLIEIARQH GLVIFADEVY DKIVYDGKKH TSMAALSEDV
     LTVTFNSLSK SYRSCGYRAG WMFISGLTGE NRRHAKDYFE GLGILASMRL CPNVPGQYAI
     QTALGGYQSI NDLIVPGGRL YKQRELAYDM LTAIPGVSCV KPEAALYMFP RLDPKVYPIQ
     NDQQFILDLL LEERVLLVQG TGFNWKTPDH FRVVFLPNVD DLADSINRIA RFLDGYRKRH
     TA
//