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Protein

Thymidine kinase

Gene

tdk

Organism
Ferrimonas balearica (strain DSM 9799 / CCM 4581 / PAT)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei88Proton acceptorUniRule annotation1
Metal bindingi145ZincUniRule annotation1
Metal bindingi147ZincUniRule annotation1
Metal bindingi182ZincUniRule annotation1
Metal bindingi185ZincUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi9 – 16ATPUniRule annotation8
Nucleotide bindingi87 – 90ATPUniRule annotation4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseUniRule annotationImported, Transferase
Biological processDNA synthesisUniRule annotation
LigandATP-bindingUniRule annotation, Metal-bindingUniRule annotation, Nucleotide-binding, ZincUniRule annotation

Enzyme and pathway databases

BioCyciFBAL550540:G1GN9-1034-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkUniRule annotation
Ordered Locus Names:Fbal_0983Imported
OrganismiFerrimonas balearica (strain DSM 9799 / CCM 4581 / PAT)Imported
Taxonomic identifieri550540 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesFerrimonadaceaeFerrimonas
Proteomesi
  • UP000006683 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi550540.Fbal_0983

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107104 Bacteria
COG1435 LUCA
HOGENOMiHOG000076391
KOiK00857
OMAiKEQFGWI
OrthoDBiPOG091H0659

Family and domain databases

HAMAPiMF_00124 Thymidine_kinase, 1 hit
InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR001267 Thymidine_kinase
IPR020633 Thymidine_kinase_CS
PANTHERiPTHR11441 PTHR11441, 1 hit
PfamiView protein in Pfam
PF00265 TK, 1 hit
PIRSFiPIRSF035805 TK_cell, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00603 TK_CELLULAR_TYPE, 1 hit

Sequencei

Sequence statusi: Complete.

E1SU45-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQLYFYYSA MNAGKSTSLL QSAYNYRERG MVPLVLTAGL DDRYGVGKIT
60 70 80 90 100
SRIGLESEAL IYRSEDNLIE LIKTEVAKGA VHCILVDESQ FLTKLQVQQL
110 120 130 140 150
THVVDNLDIP VLCYGLRTDF QGELFEGAQY LLAWADKLVE LKTICHCGRK
160 170 180 190
ANMVVRMDAE GNPVRDGDQV QIGGNDSYVS MCRTHFRELV WD
Length:192
Mass (Da):21,637
Last modified:November 30, 2010 - v1
Checksum:iDF6615DE33FD3B5F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002209 Genomic DNA Translation: ADN75192.1
RefSeqiWP_013344498.1, NC_014541.1

Genome annotation databases

EnsemblBacteriaiADN75192; ADN75192; Fbal_0983
KEGGifbl:Fbal_0983

Similar proteinsi

Entry informationi

Entry nameiE1SU45_FERBD
AccessioniPrimary (citable) accession number: E1SU45
Entry historyiIntegrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: March 28, 2018
This is version 43 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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