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Protein

DNA mismatch repair protein MutH

Gene

mutH

Organism
Pantoea vagans (strain C9-1) (Pantoea agglomerans (strain C9-1))
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

EndonucleaseUniRule annotationSAAS annotation, Hydrolase, Nuclease

Keywords - Biological processi

DNA damage, DNA repairUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
DNA mismatch repair protein MutHUniRule annotationSAAS annotation
Alternative name(s):
Methyl-directed mismatch repair proteinUniRule annotation
Gene namesi
Name:mutHUniRule annotationImported
Ordered Locus Names:Pvag_2504Imported
OrganismiPantoea vagans (strain C9-1) (Pantoea agglomerans (strain C9-1))Imported
Taxonomic identifieri712898 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesErwiniaceaePantoea
Proteomesi
  • UP000006631 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi712898.Pvag_2504.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini56 – 154MutHInterPro annotationAdd BLAST99

Sequence similaritiesi

Belongs to the MutH family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105IRT. Bacteria.
COG3066. LUCA.
HOGENOMiHOG000271839.
KOiK03573.
OMAiVMQLRPK.
OrthoDBiPOG091H04RA.

Family and domain databases

CDDicd00583. MutH_Sau3AI. 1 hit.
Gene3Di3.40.600.10. 1 hit.
HAMAPiMF_00759. MutH. 1 hit.
InterProiIPR004230. DNA_mismatch_repair_MutH.
IPR011337. DNA_rep_MutH/RE_typeII.
IPR011335. Restrct_endonuc-II-like.
[Graphical view]
PfamiPF02976. MutH. 1 hit.
[Graphical view]
SMARTiSM00927. MutH. 1 hit.
[Graphical view]
SUPFAMiSSF52980. SSF52980. 1 hit.
TIGRFAMsiTIGR02248. mutH_TIGR. 1 hit.

Sequencei

Sequence statusi: Complete.

E1SCV3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRYPPGPPED EASLLARAQD LAGLPMETLA ARAGLPMPAD LKRDKGWVGM
60 70 80 90 100
LLEWHLGASA GSKAEQDFAH LGIELKTIPI DAQGKPLETT FVCVAPLTGN
110 120 130 140 150
SGVTWLTSHV RHKLARVLWI PVEGGREIPL RERRVGAPLL WSPDAEEDEM
160 170 180 190 200
LRQDWEELMD MIVLGRVEQI TARHGAWLQI RPKAANSKAL TEGIGDQGQP
210 220
IMTLPRGFYL KKSFTGPLLA RHFLL
Length:225
Mass (Da):24,875
Last modified:November 30, 2010 - v1
Checksum:iEB2D397C304FC6BC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002206 Genomic DNA. Translation: ADO10665.1.
RefSeqiWP_013358920.1. NC_014562.1.

Genome annotation databases

EnsemblBacteriaiADO10665; ADO10665; Pvag_2504.
KEGGipva:Pvag_2504.
PATRICi42421141. VBIPanVag152020_2663.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002206 Genomic DNA. Translation: ADO10665.1.
RefSeqiWP_013358920.1. NC_014562.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi712898.Pvag_2504.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADO10665; ADO10665; Pvag_2504.
KEGGipva:Pvag_2504.
PATRICi42421141. VBIPanVag152020_2663.

Phylogenomic databases

eggNOGiENOG4105IRT. Bacteria.
COG3066. LUCA.
HOGENOMiHOG000271839.
KOiK03573.
OMAiVMQLRPK.
OrthoDBiPOG091H04RA.

Family and domain databases

CDDicd00583. MutH_Sau3AI. 1 hit.
Gene3Di3.40.600.10. 1 hit.
HAMAPiMF_00759. MutH. 1 hit.
InterProiIPR004230. DNA_mismatch_repair_MutH.
IPR011337. DNA_rep_MutH/RE_typeII.
IPR011335. Restrct_endonuc-II-like.
[Graphical view]
PfamiPF02976. MutH. 1 hit.
[Graphical view]
SMARTiSM00927. MutH. 1 hit.
[Graphical view]
SUPFAMiSSF52980. SSF52980. 1 hit.
TIGRFAMsiTIGR02248. mutH_TIGR. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiE1SCV3_PANVC
AccessioniPrimary (citable) accession number: E1SCV3
Entry historyi
Integrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: November 30, 2016
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.