SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

E1S9A2

- E1S9A2_HELP9

UniProt

E1S9A2 - E1S9A2_HELP9

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Alanine racemase

Gene
alr, hp908_0956
Organism
Helicobacter pylori (strain 908)
Status
Unreviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotations

Cofactori

Pyridoxal phosphate By similarity.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei37 – 371Proton acceptor; specific for D-alanine By similarityUniRule annotation
Binding sitei135 – 1351Substrate By similarityUniRule annotation
Active sitei271 – 2711Proton acceptor; specific for L-alanine By similarityUniRule annotation
Binding sitei319 – 3191Substrate; via amide nitrogen By similarityUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciHPYL869727:GLE7-972-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Name:alrImported
Ordered Locus Names:hp908_0956Imported
OrganismiHelicobacter pylori (strain 908)Imported
Taxonomic identifieri869727 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
ProteomesiUP000008149: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei37 – 371N6-(pyridoxal phosphate)lysine By similarityUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliE1S9A2.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000031444.
KOiK01775.
OMAiITIKSHV.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E1S9A2-1 [UniParc]FASTAAdd to Basket

« Hide

MLKRASFVEV NTASLRHNFN AVKSIVPKDA CVMAVVKANA YGAGALKASE    50
IFLQEGANYL GVATLDEALE LRSHFSKTPI LILGYNPNAN ASMLIDNDLS 100
AMVFSLEQAE VFSQMALKSQ KRLKIHLKID TGMHRLGLEP TFKSIEIVKK 150
IRALKGLEVE GIFTHLSNAD ANIKTHAKNQ MKAFNAFLEQ LLNQKIEFKY 200
RHAYNSAGIL SLCNGNENRL LNLYRPGIML YGFYPSNEMK ESSQTILKNV 250
ISLKARIVQI KRVKKGEFIG YGEHFYTNEE TLVGVLALGY ADGLVRALGN 300
RIQVAINNQL APLIGKVCMD QCFVKLNGIE AKEGDEVILF GDKSAKANDA 350
SEIAALLNTI PYETISTLSK RLERVYI 377
Length:377
Mass (Da):41,806
Last modified:November 30, 2010 - v1
Checksum:iBBBC82A5E2135922
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002184 Genomic DNA. Translation: ADN80082.1.
RefSeqiYP_005765456.1. NC_017357.1.

Genome annotation databases

EnsemblBacteriaiADN80082; ADN80082; hp908_0956.
GeneIDi12343879.
KEGGihpi:hp908_0956.
PATRICi43059586. VBIHelPyl166603_0966.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002184 Genomic DNA. Translation: ADN80082.1 .
RefSeqi YP_005765456.1. NC_017357.1.

3D structure databases

ProteinModelPortali E1S9A2.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADN80082 ; ADN80082 ; hp908_0956 .
GeneIDi 12343879.
KEGGi hpi:hp908_0956.
PATRICi 43059586. VBIHelPyl166603_0966.

Phylogenomic databases

HOGENOMi HOG000031444.
KOi K01775.
OMAi ITIKSHV.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci HPYL869727:GLE7-972-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 908Imported.

Entry informationi

Entry nameiE1S9A2_HELP9
AccessioniPrimary (citable) accession number: E1S9A2
Entry historyi
Integrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: July 9, 2014
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi