E1S9A2 (E1S9A2_HELP9) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Alanine racemase RuleBase RU000608
EC=5.1.1.1 RuleBase RU000608

Gene names

Name:	alr EMBL ADN80082.1
Ordered Locus Names:	hp908_0956 EMBL ADN80082.1

Organism

Helicobacter pylori (strain 908) [Complete proteome] [HAMAP]

Taxonomic identifier

869727 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › delta/epsilon subdivisions › Epsilonproteobacteria › Campylobacterales › Helicobacteraceae › Helicobacter › Helicobacter pylori

Protein attributes

Sequence length	377 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-alanine = D-alanine. RuleBase RU000608 SAAS SAAS020622
Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000608 SAAS SAAS020622
Pathway	Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. SAAS SAAS020622
Sequence similarities	Belongs to the alanine racemase family. RuleBase RU004188

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU000608 SAAS SAAS020622
Molecular function	Isomerase SAAS SAAS020622 RuleBase RU000608 EMBL ADN80082.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	D-alanine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	alanine racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E1S9A2 [UniParc]. Last modified November 30, 2010. Version 1. Checksum: BBBC82A5E2135922	FASTA	377	41,806
	10 20 30 40 50 60 MLKRASFVEV NTASLRHNFN AVKSIVPKDA CVMAVVKANA YGAGALKASE IFLQEGANYL 70 80 90 100 110 120 GVATLDEALE LRSHFSKTPI LILGYNPNAN ASMLIDNDLS AMVFSLEQAE VFSQMALKSQ 130 140 150 160 170 180 KRLKIHLKID TGMHRLGLEP TFKSIEIVKK IRALKGLEVE GIFTHLSNAD ANIKTHAKNQ 190 200 210 220 230 240 MKAFNAFLEQ LLNQKIEFKY RHAYNSAGIL SLCNGNENRL LNLYRPGIML YGFYPSNEMK 250 260 270 280 290 300 ESSQTILKNV ISLKARIVQI KRVKKGEFIG YGEHFYTNEE TLVGVLALGY ADGLVRALGN 310 320 330 340 350 360 RIQVAINNQL APLIGKVCMD QCFVKLNGIE AKEGDEVILF GDKSAKANDA SEIAALLNTI 370 PYETISTLSK RLERVYI

References

[1]	"The genome of Helicobacter pylori strain 908." Devi S.H., Taylor T.D., Avasthi T.S., Kondo S., Suzuki Y., Megraud F., Ahmed N. J. Bacteriol. 192:6488-9(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 908 EMBL ADN80082.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002184 Genomic DNA. Translation: ADN80082.1.
RefSeq	YP_005765456.1. NC_017357.1.
3D structure databases
ProteinModelPortal	E1S9A2.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADN80082; ADN80082; hp908_0956.
GeneID	12343879.
KEGG	hpi:hp908_0956.
PATRIC	43059586. VBIHelPyl166603_0966.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000031444.
KO	K01775.
OMA	NFKSIEI.
Enzyme and pathway databases
UniPathway	UPA00042; UER00497.
Family and domain databases
Gene3D	2.40.37.10. 1 hit.
HAMAP	MF_01201. Ala_racemase.
InterPro	IPR000821. Ala_racemase. IPR009006. Ala_racemase/Decarboxylase_C. IPR011079. Ala_racemase_C. IPR001608. Ala_racemase_N. IPR020622. Ala_racemase_pyridoxalP-BS. [Graphical view]
Pfam	PF00842. Ala_racemase_C. 1 hit. PF01168. Ala_racemase_N. 1 hit. [Graphical view]
PRINTS	PR00992. ALARACEMASE.
SMART	SM01005. Ala_racemase_C. 1 hit. [Graphical view]
SUPFAM	SSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMs	TIGR00492. alr. 1 hit.
PROSITE	PS00395. ALANINE_RACEMASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

E1S9A2_HELP9

Accession

Primary (citable) accession number: E1S9A2

Entry history

Integrated into UniProtKB/TrEMBL:	November 30, 2010
Last sequence update:	November 30, 2010
Last modified:	May 1, 2013
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)