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E1S4B5 (E1S4B5_ECOUM) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Elongation factor Tu HAMAP-Rule MF_00118

Short name=EF-Tu HAMAP-Rule MF_00118
Gene names
Name:tuf HAMAP-Rule MF_00118
Ordered Locus Names:UM146_16765 EMBL ADN72707.1
OrganismEscherichia coli (strain UM146) [Complete proteome] [HAMAP] EMBL ADN72707.1
Taxonomic identifier869729 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length394 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity. HAMAP-Rule MF_00118 RuleBase RU000325

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00118

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00118.

Sequence similarities

Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily. HAMAP-Rule MF_00118 RuleBase RU000325

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding19 – 268GTP By similarity HAMAP-Rule MF_00118
Nucleotide binding81 – 855GTP By similarity HAMAP-Rule MF_00118
Nucleotide binding136 – 1394GTP By similarity HAMAP-Rule MF_00118

Sequences

Sequence LengthMass (Da)Tools
E1S4B5 [UniParc].

Last modified November 30, 2010. Version 1.
Checksum: 6EDA60255F43358F

FASTA39443,314
        10         20         30         40         50         60 
MSKEKFERTK PHVNVGTIGH VDHGKTTLTA AITTVLAKTY GGAARAFDQI DNAPEEKARG 

        70         80         90        100        110        120 
ITINTSHVEY DTPTRHYAHV DCPGHADYVK NMITGAAQMD GAILVVAATD GPMPQTREHI 

       130        140        150        160        170        180 
LLGRQVGVPY IIVFLNKCDM VDDEELLELV EMEVRELLSQ YDFPGDDTPI VRGSALKALE 

       190        200        210        220        230        240 
GDAEWEAKIL ELAGFLDSYI PEPERAIDKP FLLPIEDVFS ISGRGTVVTG RVERGIIKVG 

       250        260        270        280        290        300 
EEVEIVGIKE TQKSTCTGVE MFRKLLDEGR AGENVGVLLR GIKREEIERG QVLAKPGTIK 

       310        320        330        340        350        360 
PHTKFESEVY ILSKDEGGRH TPFFKGYRPQ FYFRTTDVTG TIELPEGVEM VMPGDNIKMV 

       370        380        390 
VTLIHPIAMD DGLRFAIREG GRTVGAGVVA KVLS 

« Hide

References

« Hide 'large scale' references
[1]"Complete genome sequence of adherent invasive Escherichia coli UM146 isolated from ileal Crohn's disease biopsy tissue."
Krause D.O., Little A.C., Dowd S.E., Bernstein C.N.
J. Bacteriol. 193:583-583(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: UM146 EMBL ADN72707.1.
[2]"Complete genome sequence of adherent invasive Escherichia coli UM146 isolated from ileal Crohn's disease biopsy tissue."
Krause D.O., Little A.C., Dowd S.E., Bernstein C.N.
Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: UM146.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002167 Genomic DNA. Translation: ADN72707.1.
RefSeqYP_006112219.1. NC_017632.1.

3D structure databases

ProteinModelPortalE1S4B5.
SMRE1S4B5. Positions 9-394.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEE1S4B5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADN72707; ADN72707; UM146_16765.
GeneID12701862.
KEGGelu:UM146_16765.
PATRIC42973554. VBIEscCol167775_3583.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000229290.
KOK02358.
OMAGTEMCMP.

Enzyme and pathway databases

BioCycECOL869729:GI9Z-3351-MONOMER.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
HAMAPMF_00118_B. EF_Tu_B.
InterProIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSPR00315. ELONGATNFCT.
SUPFAMSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE1S4B5_ECOUM
AccessionPrimary (citable) accession number: E1S4B5
Entry history
Integrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: June 11, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)