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Protein

Phosphoenolpyruvate carboxylase

Gene

ppcA

Organism
Methanolacinia petrolearia (strain DSM 11571 / OCM 486 / SEBR 4847) (Methanoplanus petrolearius)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Mg2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationImported

Keywords - Biological processi

Carbon dioxide fixationUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotation, PyruvateImported

Enzyme and pathway databases

BioCyciMPET679926:GHOF-743-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcAUniRule annotation
Ordered Locus Names:Mpet_0728Imported
OrganismiMethanolacinia petrolearia (strain DSM 11571 / OCM 486 / SEBR 4847) (Methanoplanus petrolearius)Imported
Taxonomic identifieri679926 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanomicrobialesMethanomicrobiaceaeMethanolacinia
ProteomesiUP000006565 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi679926.Mpet_0728.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 2 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000038601.
KOiK01595.
OMAiYIQPRDI.

Family and domain databases

HAMAPiMF_01904. PEPcase_type2.
InterProiIPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF14010. PEPcase_2. 1 hit.
[Graphical view]
PIRSFiPIRSF006677. UCP006677. 1 hit.
SUPFAMiSSF51621. SSF51621. 1 hit.
TIGRFAMsiTIGR02751. PEPCase_arch. 1 hit.

Sequencei

Sequence statusi: Complete.

E1RII9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSADYSHVPR CMSTQHPDNV HPPFFAQNPV LEGEDEVVEA YYVYSNLGCD
60 70 80 90 100
EQMWDCEGKE VDSFVVKKLL SRYGDYFSER QIGREKFLTL RVPNPEIEHT
110 120 130 140 150
EGKILLETLE SIPRSFDLAS LFYKNDFAPI FEVILPMTSS FESIDNIYQY
160 170 180 190 200
YRDFVVGKKD KRLGGRDCTI ADWVGDIRPE KINVIPLFED MKSILNSDKI
210 220 230 240 250
LRRYIDGKKI DYQRVFFARS DPAMNYGLIG AVLLNKIGLY KAGAVSEATG
260 270 280 290 300
VPVLPIIGAG SAPFRGNLRP DTIRRTLAEY PGAWTFTVQS AFKYDYPAED
310 320 330 340 350
VRKAVEELKK APVNPAPEIS EERCTDIVER YSAEYNRHLK ELAGLVNRVA
360 370 380 390 400
PYVPQRRKRK LHIGLFGYSR SSGDIELPRA ITFTAAMYSI GVPPEILGLS
410 420 430 440 450
ALKENDMEYL HEVYANFEQD ILDSLRYLNP ESPYIPEGIM EFVGDHFDFE
460 470 480
TNPDHTNITN KIIADITGNS CFEMQNDILA AAGIRKFIG
Length:489
Mass (Da):55,579
Last modified:November 30, 2010 - v1
Checksum:i97F79898E0808820
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002117 Genomic DNA. Translation: ADN35502.1.
RefSeqiWP_013328680.1. NC_014507.1.
YP_003893940.1. NC_014507.1.

Genome annotation databases

EnsemblBacteriaiADN35502; ADN35502; Mpet_0728.
GeneIDi9743181.
KEGGimpi:Mpet_0728.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002117 Genomic DNA. Translation: ADN35502.1.
RefSeqiWP_013328680.1. NC_014507.1.
YP_003893940.1. NC_014507.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi679926.Mpet_0728.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADN35502; ADN35502; Mpet_0728.
GeneIDi9743181.
KEGGimpi:Mpet_0728.

Phylogenomic databases

HOGENOMiHOG000038601.
KOiK01595.
OMAiYIQPRDI.

Enzyme and pathway databases

BioCyciMPET679926:GHOF-743-MONOMER.

Family and domain databases

HAMAPiMF_01904. PEPcase_type2.
InterProiIPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF14010. PEPcase_2. 1 hit.
[Graphical view]
PIRSFiPIRSF006677. UCP006677. 1 hit.
SUPFAMiSSF51621. SSF51621. 1 hit.
TIGRFAMsiTIGR02751. PEPCase_arch. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 11571 / OCM 486 / SEBR 4847Imported.

Entry informationi

Entry nameiE1RII9_METP4
AccessioniPrimary (citable) accession number: E1RII9
Entry historyi
Integrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: June 24, 2015
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.