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E1RHY1 (E1RHY1_METP4) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 21. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable cobyrinic acid A,C-diamide synthase HAMAP-Rule MF_00027
Gene names
Name:cobB HAMAP-Rule MF_00027
Ordered Locus Names:Mpet_1766
OrganismMethanoplanus petrolearius (strain DSM 11571 / OCM 486 / SEBR 4847) [Complete proteome] [HAMAP] EMBL ADN36519.1
Taxonomic identifier679926 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Methanomicrobia › Methanomicrobiales › Methanomicrobiaceae › Methanoplanus ›

Protein attributes

Sequence length437 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH2 groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation By similarity. HAMAP-Rule MF_00027

Pathway

Cofactor biosynthesis; adenosylcobalamin biosynthesis. HAMAP-Rule MF_00027

Sequence similarities

Belongs to the CobB/CobQ family. CobB subfamily. HAMAP-Rule MF_00027

Contains 1 GATase cobBQ-type domain. HAMAP-Rule MF_00027

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain238 – 428191GATase cobBQ-type By similarity HAMAP-Rule MF_00027

Sites

Active site3181Nucleophile By similarity HAMAP-Rule MF_00027
Active site4201 By similarity HAMAP-Rule MF_00027

Sequences

Sequence LengthMass (Da)Tools
E1RHY1 [UniParc].

Last modified November 30, 2010. Version 1.
Checksum: 2E9C5A7BC71836EA

FASTA43748,190
        10         20         30         40         50         60 
MIPAIIVAGT HSGCGKTTIA GALMSALVKR GLIVQPFKVG PDFIDPTHHT AICGRYSRNL 

        70         80         90        100        110        120 
DPFMMGEDGV IDTFVRACEG ADIAVIEGVM GLYDGLEGED YGSTAHVSKI LGCPVVLVAD 

       130        140        150        160        170        180 
TKGSSRSINA VVKGFDIFDR DIDITGVIYN RIGSPRHREM IECSIVKKAY GWIPFEKGKS 

       190        200        210        220        230        240 
VESRHLGIQM AYETSSISEF GDVLEENCNI DAIIEDAKSN LDYKEIVGEK TDADCKIRIG 

       250        260        270        280        290        300 
VAHDRAFNFY YADNFDLLRR NGAELIFFSP ISDRLPEVDA LYFGGGYPEL FGEELEVSKC 

       310        320        330        340        350        360 
REDVKKAADS GMPVYAECGG LTYLTERIEI DGKKSKMCGL IPAETIKMDR FQALGYVDAE 

       370        380        390        400        410        420 
CTVSDCIIPQ GTCYRGHEFH YTKLTGLEDV KYALKLKRGR GIEDGKDGIY TSNILAGYTH 

       430 
AYFTDKFTKT LIETKFQ

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002117 Genomic DNA. Translation: ADN36519.1.
RefSeqYP_003894957.1. NC_014507.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADN36519; ADN36519; Mpet_1766.
GeneID9744241.
KEGGmpi:Mpet_1766.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000289958.
KOK02224.
OMAFIDPSHH.

Enzyme and pathway databases

BioCycMPET679926:GHOF-1804-MONOMER.
UniPathwayUPA00148.

Family and domain databases

HAMAPMF_00027. CobB.
InterProIPR004484. CbiA_synth.
IPR017929. CobB/CobQ_GATase.
IPR002586. CobQ/CobB/MinD/ParA_Nub-bd_dom.
IPR011698. GATase_3.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamPF01656. CbiA. 1 hit.
PF07685. GATase_3. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR00379. cobB. 1 hit.
PROSITEPS51274. GATASE_COBBQ. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE1RHY1_METP4
AccessionPrimary (citable) accession number: E1RHY1
Entry history
Integrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: May 29, 2013
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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