ID   E1RED1_METP4            Unreviewed;       464 AA.
AC   E1RED1;
DT   30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2010, sequence version 1.
DT   27-MAR-2024, entry version 60.
DE   RecName: Full=glutamate decarboxylase {ECO:0000256|ARBA:ARBA00012421};
DE            EC=4.1.1.15 {ECO:0000256|ARBA:ARBA00012421};
GN   OrderedLocusNames=Mpet_2428 {ECO:0000313|EMBL:ADN37174.1};
OS   Methanolacinia petrolearia (strain DSM 11571 / OCM 486 / SEBR 4847)
OS   (Methanoplanus petrolearius).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanomicrobiales; Methanomicrobiaceae; Methanolacinia.
OX   NCBI_TaxID=679926 {ECO:0000313|EMBL:ADN37174.1, ECO:0000313|Proteomes:UP000006565};
RN   [1] {ECO:0000313|EMBL:ADN37174.1, ECO:0000313|Proteomes:UP000006565}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 11571 / OCM 486 / SEBR 4847
RC   {ECO:0000313|Proteomes:UP000006565};
RX   PubMed=21304750;
RA   Brambilla E., Djao O.D., Daligault H., Lapidus A., Lucas S., Hammon N.,
RA   Nolan M., Tice H., Cheng J.F., Han C., Tapia R., Goodwin L., Pitluck S.,
RA   Liolios K., Ivanova N., Mavromatis K., Mikhailova N., Pati A., Chen A.,
RA   Palaniappan K., Land M., Hauser L., Chang Y.J., Jeffries C.D., Rohde M.,
RA   Spring S., Sikorski J., Goker M., Woyke T., Bristow J., Eisen J.A.,
RA   Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT   "Complete genome sequence of Methanoplanus petrolearius type strain (SEBR
RT   4847).";
RL   Stand. Genomic Sci. 3:203-211(2010).
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933,
CC         ECO:0000256|PIRSR:PIRSR602129-50, ECO:0000256|RuleBase:RU000382};
CC   -!- SIMILARITY: Belongs to the group II decarboxylase family.
CC       {ECO:0000256|RuleBase:RU000382}.
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DR   EMBL; CP002117; ADN37174.1; -; Genomic_DNA.
DR   RefSeq; WP_013330351.1; NC_014507.1.
DR   AlphaFoldDB; E1RED1; -.
DR   STRING; 679926.Mpet_2428; -.
DR   GeneID; 9744921; -.
DR   KEGG; mpi:Mpet_2428; -.
DR   eggNOG; arCOG00027; Archaea.
DR   HOGENOM; CLU_019582_2_1_2; -.
DR   OrthoDB; 56891at2157; -.
DR   Proteomes; UP000006565; Chromosome.
DR   GO; GO:0004351; F:glutamate decarboxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0006536; P:glutamate metabolic process; IEA:InterPro.
DR   CDD; cd06450; DOPA_deC_like; 1.
DR   Gene3D; 3.90.1150.160; -; 1.
DR   Gene3D; 4.10.280.50; -; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR010107; Glutamate_decarboxylase.
DR   InterPro; IPR002129; PyrdxlP-dep_de-COase.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   NCBIfam; TIGR01788; Glu-decarb-GAD; 1.
DR   PANTHER; PTHR43321; GLUTAMATE DECARBOXYLASE; 1.
DR   PANTHER; PTHR43321:SF3; GLUTAMATE DECARBOXYLASE; 1.
DR   Pfam; PF00282; Pyridoxal_deC; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|RuleBase:RU000382};
KW   Pyridoxal phosphate {ECO:0000256|PIRSR:PIRSR602129-50,
KW   ECO:0000256|RuleBase:RU000382};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006565}.
FT   MOD_RES         278
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR602129-50"
SQ   SEQUENCE   464 AA;  52443 MW;  D1FD00CBFF11FA0D CRC64;
     MGLKHPKGPK HNAKEIRIDP IFAQEGFRSI PRCSMPEKEM SPDLAYQIVH DELMLDGNAR
     LNLATFVGTW MEPQAQKLAS ETFDKNMIDK DEYPQTAELE MRCVSILSHL WNSPDPDNST
     GCSTTGSSEA AMLGGLAMKR RWQHKRKAGG KPIDNPNIVM GINVQVCWEK FANYWDVEMR
     LVPMEGNRFH LSAEEAIKLC DENTIGVIAI LGSTFDGSYE PVKEICGALD KFHEKTGIDI
     PVHVDAASGG MIAPFLDQDL IWDFRLQRVA SINTSGHKYG LVYPGVGWVV WRDAKMLPED
     LIFYVNYLGS NMPTFALNFS RPGSQIILQY YNFLRLGFDG YTKVQGYARE VAMYLSKEIE
     NLGPFELITR GDELPVFAFK LRDSVKNFSV FDVSNKMRER GWLIPAYTFP ANRTDLAALR
     IVVRRGLSQD LADLFLDDLK RQLPILQSQP EPVHDEKSGS GFHH
//