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E1R8J8

- E1R8J8_SPISS

UniProt

E1R8J8 - E1R8J8_SPISS

Protein

Cobalt-precorrin-5B C(1)-methyltransferase

Gene

cbiD

Organism
Spirochaeta smaragdinae (strain DSM 11293 / JCM 15392 / SEBR 4228)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 26 (01 Oct 2014)
      Sequence version 1 (30 Nov 2010)
      Previous versions | rss
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    Functioni

    Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.UniRule annotation

    Catalytic activityi

    Cobalt-precorrin-5B + S-adenosyl-L-methionine = cobalt-precorrin-6A + S-adenosyl-L-homocysteine.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. methyltransferase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. cobalamin biosynthetic process Source: UniProtKB-UniPathway
    2. corrin biosynthetic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    MethyltransferaseUniRule annotation, Transferase

    Keywords - Biological processi

    Cobalamin biosynthesisUniRule annotation

    Keywords - Ligandi

    S-adenosyl-L-methionineUniRule annotation

    Enzyme and pathway databases

    BioCyciSSMA573413:GI0C-190-MONOMER.
    UniPathwayiUPA00148; UER00227.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cobalt-precorrin-5B C(1)-methyltransferaseUniRule annotation (EC:2.1.1.195UniRule annotation)
    Alternative name(s):
    Cobalt-precorrin-6A synthaseUniRule annotation
    Gene namesi
    Name:cbiDUniRule annotation
    Ordered Locus Names:Spirs_0185Imported
    OrganismiSpirochaeta smaragdinae (strain DSM 11293 / JCM 15392 / SEBR 4228)Imported
    Taxonomic identifieri573413 [NCBI]
    Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeSpirochaeta
    ProteomesiUP000002318: Chromosome

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the CbiD family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000009126.
    KOiK02188.
    OMAiPRRMISE.

    Family and domain databases

    HAMAPiMF_00787. CbiD.
    InterProiIPR002748. Cbl_biosynth_CbiD.
    [Graphical view]
    PfamiPF01888. CbiD. 1 hit.
    [Graphical view]
    PIRSFiPIRSF026782. CbiD. 1 hit.
    SUPFAMiSSF111342. SSF111342. 1 hit.
    TIGRFAMsiTIGR00312. cbiD. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    E1R8J8-1 [UniParc]FASTAAdd to Basket

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    MAQWYDQELG KVSGMRLGIT TGSCAQAAAR AALEFLLGIF ADKRVEITLP    50
    KGHRRYSGRQ ILVPVESIGA TSDGTGAEAL VRKDSGDDPD ITDGILIGAR 100
    VRLKEGNGVE IDGAEGVGRI TRPGLAGKVG EAAINPIPRR MIREELLPLL 150
    PEGKGCRVEI FVPEGIALAE KTWNPRIGIL GGISIIGTKG VVEPKSEEAY 200
    KASINRVIHS YLKSGMSRLI ITPGYVGEAF LSSRGIALDR VVTVGDHVGH 250
    ALLRGADHGA KELLLVGHIG KLTKIAVAMF NTHWSSGDAR LEVIAAYAGA 300
    AGASAEKVRR LLSLSLAEEA VALIHDWGLD EIWNAIARRA AERTEKLVEG 350
    RCTIGVVLLD LKGHSLGSWP KERVEGWLK 379
    Length:379
    Mass (Da):40,496
    Last modified:November 30, 2010 - v1
    Checksum:i4A6508D904DD48AB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002116 Genomic DNA. Translation: ADK79342.1.
    RefSeqiYP_003801936.1. NC_014364.1.

    Genome annotation databases

    EnsemblBacteriaiADK79342; ADK79342; Spirs_0185.
    GeneIDi9488262.
    KEGGissm:Spirs_0185.
    PATRICi42524220. VBISpiSma89994_0190.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002116 Genomic DNA. Translation: ADK79342.1 .
    RefSeqi YP_003801936.1. NC_014364.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADK79342 ; ADK79342 ; Spirs_0185 .
    GeneIDi 9488262.
    KEGGi ssm:Spirs_0185.
    PATRICi 42524220. VBISpiSma89994_0190.

    Phylogenomic databases

    HOGENOMi HOG000009126.
    KOi K02188.
    OMAi PRRMISE.

    Enzyme and pathway databases

    UniPathwayi UPA00148 ; UER00227 .
    BioCyci SSMA573413:GI0C-190-MONOMER.

    Family and domain databases

    HAMAPi MF_00787. CbiD.
    InterProi IPR002748. Cbl_biosynth_CbiD.
    [Graphical view ]
    Pfami PF01888. CbiD. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF026782. CbiD. 1 hit.
    SUPFAMi SSF111342. SSF111342. 1 hit.
    TIGRFAMsi TIGR00312. cbiD. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 11293 / JCM 15392 / SEBR 4228Imported.

    Entry informationi

    Entry nameiE1R8J8_SPISS
    AccessioniPrimary (citable) accession number: E1R8J8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 30, 2010
    Last sequence update: November 30, 2010
    Last modified: October 1, 2014
    This is version 26 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3