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E1R8J8

- E1R8J8_SPISS

UniProt

E1R8J8 - E1R8J8_SPISS

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Protein

Cobalt-precorrin-5B C(1)-methyltransferase

Gene

cbiD

Organism
Spirochaeta smaragdinae (strain DSM 11293 / JCM 15392 / SEBR 4228)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.UniRule annotation

Catalytic activityi

Cobalt-precorrin-5B + S-adenosyl-L-methionine = cobalt-precorrin-6A + S-adenosyl-L-homocysteine.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. methyltransferase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. cobalamin biosynthetic process Source: UniProtKB-UniPathway
  2. corrin biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotation, Transferase

Keywords - Biological processi

Cobalamin biosynthesisUniRule annotation

Keywords - Ligandi

S-adenosyl-L-methionineUniRule annotation

Enzyme and pathway databases

BioCyciSSMA573413:GI0C-190-MONOMER.
UniPathwayiUPA00148; UER00227.

Names & Taxonomyi

Protein namesi
Recommended name:
Cobalt-precorrin-5B C(1)-methyltransferaseUniRule annotation (EC:2.1.1.195UniRule annotation)
Alternative name(s):
Cobalt-precorrin-6A synthaseUniRule annotation
Gene namesi
Name:cbiDUniRule annotation
Ordered Locus Names:Spirs_0185Imported
OrganismiSpirochaeta smaragdinae (strain DSM 11293 / JCM 15392 / SEBR 4228)Imported
Taxonomic identifieri573413 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeSpirochaeta
ProteomesiUP000002318: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the CbiD family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000009126.
KOiK02188.
OMAiPRRMISE.

Family and domain databases

HAMAPiMF_00787. CbiD.
InterProiIPR002748. Cbl_biosynth_CbiD.
[Graphical view]
PfamiPF01888. CbiD. 1 hit.
[Graphical view]
PIRSFiPIRSF026782. CbiD. 1 hit.
SUPFAMiSSF111342. SSF111342. 1 hit.
TIGRFAMsiTIGR00312. cbiD. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

E1R8J8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAQWYDQELG KVSGMRLGIT TGSCAQAAAR AALEFLLGIF ADKRVEITLP
60 70 80 90 100
KGHRRYSGRQ ILVPVESIGA TSDGTGAEAL VRKDSGDDPD ITDGILIGAR
110 120 130 140 150
VRLKEGNGVE IDGAEGVGRI TRPGLAGKVG EAAINPIPRR MIREELLPLL
160 170 180 190 200
PEGKGCRVEI FVPEGIALAE KTWNPRIGIL GGISIIGTKG VVEPKSEEAY
210 220 230 240 250
KASINRVIHS YLKSGMSRLI ITPGYVGEAF LSSRGIALDR VVTVGDHVGH
260 270 280 290 300
ALLRGADHGA KELLLVGHIG KLTKIAVAMF NTHWSSGDAR LEVIAAYAGA
310 320 330 340 350
AGASAEKVRR LLSLSLAEEA VALIHDWGLD EIWNAIARRA AERTEKLVEG
360 370
RCTIGVVLLD LKGHSLGSWP KERVEGWLK
Length:379
Mass (Da):40,496
Last modified:November 30, 2010 - v1
Checksum:i4A6508D904DD48AB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002116 Genomic DNA. Translation: ADK79342.1.
RefSeqiWP_013252806.1. NC_014364.1.
YP_003801936.1. NC_014364.1.

Genome annotation databases

EnsemblBacteriaiADK79342; ADK79342; Spirs_0185.
GeneIDi9488262.
KEGGissm:Spirs_0185.
PATRICi42524220. VBISpiSma89994_0190.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002116 Genomic DNA. Translation: ADK79342.1 .
RefSeqi WP_013252806.1. NC_014364.1.
YP_003801936.1. NC_014364.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADK79342 ; ADK79342 ; Spirs_0185 .
GeneIDi 9488262.
KEGGi ssm:Spirs_0185.
PATRICi 42524220. VBISpiSma89994_0190.

Phylogenomic databases

HOGENOMi HOG000009126.
KOi K02188.
OMAi PRRMISE.

Enzyme and pathway databases

UniPathwayi UPA00148 ; UER00227 .
BioCyci SSMA573413:GI0C-190-MONOMER.

Family and domain databases

HAMAPi MF_00787. CbiD.
InterProi IPR002748. Cbl_biosynth_CbiD.
[Graphical view ]
Pfami PF01888. CbiD. 1 hit.
[Graphical view ]
PIRSFi PIRSF026782. CbiD. 1 hit.
SUPFAMi SSF111342. SSF111342. 1 hit.
TIGRFAMsi TIGR00312. cbiD. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 11293 / JCM 15392 / SEBR 4228Imported.

Entry informationi

Entry nameiE1R8J8_SPISS
AccessioniPrimary (citable) accession number: E1R8J8
Entry historyi
Integrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: October 29, 2014
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3