E1R8J8 (E1R8J8_SPISS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Putative cobalt-precorrin-6A synthase [deacetylating] HAMAP-Rule MF_00787
EC=2.1.1.- HAMAP-Rule MF_00787

Gene names

Name:	cbiD HAMAP-Rule MF_00787
Ordered Locus Names:	Spirs_0185

Organism

Spirochaeta smaragdinae (strain DSM 11293 / JCM 15392 / SEBR 4228) [Complete proteome] [HAMAP]

Taxonomic identifier

573413 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Spirochaetes › Spirochaetia › Spirochaetales › Spirochaetaceae › Spirochaeta › Spirochaeta smaragdinae

Protein attributes

Sequence length	379 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	May catalyze the methylation of C-1 in cobalt-precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A By similarity. HAMAP-Rule MF_00787
Pathway	Cofactor biosynthesis; adenosylcobalamin biosynthesis; cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route): step 6/10. HAMAP-Rule MF_00787
Sequence similarities	Belongs to the CbiD family. HAMAP-Rule MF_00787

Ontologies

Keywords
Biological process	Cobalamin biosynthesis HAMAP-Rule MF_00787
Molecular function	Transferase HAMAP-Rule MF_00787
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	cobalamin biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway corrin biosynthetic process Inferred from electronic annotation. Source: HAMAP methylation Inferred from electronic annotation. Source: GOC
Molecular_function	cobalamin-transporting ATPase activity Inferred from electronic annotation. Source: HAMAP methyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E1R8J8 [UniParc]. Last modified November 30, 2010. Version 1. Checksum: 4A6508D904DD48AB	FASTA	379	40,496
	10 20 30 40 50 60 MAQWYDQELG KVSGMRLGIT TGSCAQAAAR AALEFLLGIF ADKRVEITLP KGHRRYSGRQ 70 80 90 100 110 120 ILVPVESIGA TSDGTGAEAL VRKDSGDDPD ITDGILIGAR VRLKEGNGVE IDGAEGVGRI 130 140 150 160 170 180 TRPGLAGKVG EAAINPIPRR MIREELLPLL PEGKGCRVEI FVPEGIALAE KTWNPRIGIL 190 200 210 220 230 240 GGISIIGTKG VVEPKSEEAY KASINRVIHS YLKSGMSRLI ITPGYVGEAF LSSRGIALDR 250 260 270 280 290 300 VVTVGDHVGH ALLRGADHGA KELLLVGHIG KLTKIAVAMF NTHWSSGDAR LEVIAAYAGA 310 320 330 340 350 360 AGASAEKVRR LLSLSLAEEA VALIHDWGLD EIWNAIARRA AERTEKLVEG RCTIGVVLLD 370 LKGHSLGSWP KERVEGWLK

References

[1]

"Complete genome sequence of Spirochaeta smaragdinae type strain (SEBR 4228)." Mavromatis K., Yasawong M., Chertkov O., Lapidus A., Lucas S., Nolan M., Glavina Del Rio T., Tice H., Cheng J., Pitluck S., Liolios K., Ivanova N., Tapia R., Han C., Bruce D., Goodwin L., Pati A., Chen A. , Palaniappan K., Land M., Hauser L., Chang Y., Jeffries C., Detter J., Rohde M., Brambilla E., Spring S., Goker M., Sikorski J., Woyke T., Bristow J., Eisen J., Markowitz V., Hugenholtz P., Klenk H., Kyrpides N. Stand. Genomic Sci. 3:136-144(2010) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 11293 / JCM 15392 / SEBR 4228.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002116 Genomic DNA. Translation: ADK79342.1.
RefSeq	YP_003801936.1. NC_014364.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADK79342; ADK79342; Spirs_0185.
GeneID	9488262.
KEGG	ssm:Spirs_0185.
PATRIC	42524220. VBISpiSma89994_0190.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000009126.
KO	K02188.
OMA	ASEDTMR.
Enzyme and pathway databases
UniPathway	UPA00148; UER00227.
Family and domain databases
HAMAP	MF_00787. CbiD.
InterPro	IPR002748. Cbl_biosynth_CbiD. [Graphical view]
Pfam	PF01888. CbiD. 1 hit. [Graphical view]
PIRSF	PIRSF026782. CbiD. 1 hit.
SUPFAM	SSF111342. Cbl_biosynth_CbiD. 1 hit.
TIGRFAMs	TIGR00312. cbiD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

E1R8J8_SPISS

Accession

Primary (citable) accession number: E1R8J8

Entry history

Integrated into UniProtKB/TrEMBL:	November 30, 2010
Last sequence update:	November 30, 2010
Last modified:	May 1, 2013
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)