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Protein

Glutamine--tRNA ligase

Gene

glnS

Organism
Spirochaeta smaragdinae (strain DSM 11293 / JCM 15392 / SEBR 4228)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei271ATPUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetaseUniRule annotationSAAS annotationImported, Ligase

Keywords - Biological processi

Protein biosynthesisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine--tRNA ligaseUniRule annotationSAAS annotation (EC:6.1.1.18UniRule annotationSAAS annotation)
Alternative name(s):
Glutaminyl-tRNA synthetaseUniRule annotation
Gene namesi
Name:glnSUniRule annotation
Ordered Locus Names:Spirs_1481Imported
OrganismiSpirochaeta smaragdinae (strain DSM 11293 / JCM 15392 / SEBR 4228)Imported
Taxonomic identifieri573413 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeSpirochaeta
Proteomesi
  • UP000002318 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Monomer.UniRule annotationSAAS annotation

Protein-protein interaction databases

STRINGi573413.Spirs_1481.

Structurei

3D structure databases

ProteinModelPortaliE1R573.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini27 – 337tRNA-synt_1cInterPro annotationAdd BLAST311
Domaini340 – 530tRNA-synt_1c_CInterPro annotationAdd BLAST191

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi34 – 44"HIGH" regionUniRule annotationAdd BLAST11
Motifi268 – 272"KMSKS" regionUniRule annotation5

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CX6. Bacteria.
COG0008. LUCA.
HOGENOMiHOG000259232.
KOiK01886.
OMAiHCTYDPE.
OrthoDBiPOG091H00G9.

Family and domain databases

Gene3Di1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
HAMAPiMF_00126. Gln_tRNA_synth. 1 hit.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth.
IPR022861. Gln_tRNA_ligase_bac.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamiPF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
[Graphical view]
PRINTSiPR00987. TRNASYNTHGLU.
SUPFAMiSSF50715. SSF50715. 1 hit.
TIGRFAMsiTIGR00440. glnS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E1R573-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADAEKSSLN FIERIIEDDF ARGKHSQVVT RFPPEPNGYL HIGHAKSICL
60 70 80 90 100
NFGLAKKYGG RCHLRFDDTN PEKESLEYIE SIKRDVQWLG FSWGAHEYYA
110 120 130 140 150
SDYFEELYKR AVRLIKAGKA YVDDLSPEQM REYRGTLTKP GKESPNRTRS
160 170 180 190 200
IEENLDLFER MRKGEFPDGS MLLRAKIDMA SGNMNMRDPA LYRIRRINHH
210 220 230 240 250
RTGDAWCIYP MYDFTHPLSD AIEGITHSIC TLEFEDHRPL YDWSVEETEM
260 270 280 290 300
ECHPRQIEFA RLNLTYTVMS KRILLQLVTE GHVSGWDDPR MPTISGLRRR
310 320 330 340 350
GYTPEAIRQF ADIIGVAKVN STVDMALLEH CLREDLNLRA LRVMVVLDPV
360 370 380 390 400
KVVIDNYPEG KEELLEAENN PEDPDGGMRM VPFSREVYIE REDFMEDPPK
410 420 430 440 450
KFFRLAPGRE IRLKHAYYIT CVSVEKNEAG EITTIHCSYD PESRGGGTPD
460 470 480 490 500
GRRVKGTSHW VSVSHAKELE VRLYDNLFTS PEPGSRTGNF LDDLNPDSLS
510 520 530 540 550
TIKAMAEPSL IDAEPEAHYQ FLRKGYFTVD PKESKKGAPV FNRTVTLRDS
560
WAKLQKKIEA
Length:560
Mass (Da):64,472
Last modified:November 30, 2010 - v1
Checksum:i64EE2ED90EC8E409
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002116 Genomic DNA. Translation: ADK80608.1.
RefSeqiWP_013254072.1. NC_014364.1.

Genome annotation databases

EnsemblBacteriaiADK80608; ADK80608; Spirs_1481.
KEGGissm:Spirs_1481.
PATRICi42526916. VBISpiSma89994_1526.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002116 Genomic DNA. Translation: ADK80608.1.
RefSeqiWP_013254072.1. NC_014364.1.

3D structure databases

ProteinModelPortaliE1R573.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi573413.Spirs_1481.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADK80608; ADK80608; Spirs_1481.
KEGGissm:Spirs_1481.
PATRICi42526916. VBISpiSma89994_1526.

Phylogenomic databases

eggNOGiENOG4105CX6. Bacteria.
COG0008. LUCA.
HOGENOMiHOG000259232.
KOiK01886.
OMAiHCTYDPE.
OrthoDBiPOG091H00G9.

Family and domain databases

Gene3Di1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
HAMAPiMF_00126. Gln_tRNA_synth. 1 hit.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth.
IPR022861. Gln_tRNA_ligase_bac.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamiPF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
[Graphical view]
PRINTSiPR00987. TRNASYNTHGLU.
SUPFAMiSSF50715. SSF50715. 1 hit.
TIGRFAMsiTIGR00440. glnS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiE1R573_SPISS
AccessioniPrimary (citable) accession number: E1R573
Entry historyi
Integrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: November 30, 2016
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.