E1R460 (E1R460_SPISS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Alanine racemase EMBL ADK80482.1
EC=5.1.1.1 EMBL ADK80482.1

Gene names

Name:	alr1
Ordered Locus Names:	Spirs_1355

Organism

Spirochaeta smaragdinae (strain DSM 11293 / JCM 15392 / SEBR 4228) [Complete proteome] [HAMAP]

Taxonomic identifier

573413 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Spirochaetes › Spirochaetia › Spirochaetales › Spirochaetaceae › Spirochaeta › Spirochaeta smaragdinae

Protein attributes

Sequence length	371 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-alanine = D-alanine. SAAS SAAS020622 RuleBase RU000608
Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000608 SAAS SAAS020622
Pathway	Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. SAAS SAAS020622 RuleBase RU004247
Sequence similarities	Belongs to the alanine racemase family. RuleBase RU004188

Ontologies

Keywords
Ligand	Pyridoxal phosphate SAAS SAAS020622 RuleBase RU000608
Molecular function	Isomerase SAAS SAAS020622 RuleBase RU000608 EMBL ADK80482.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	D-alanine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	alanine racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E1R460 [UniParc]. Last modified November 30, 2010. Version 1. Checksum: 4C8EB89F068EDA6F	FASTA	371	40,768
	10 20 30 40 50 60 MRPTKARIDL DLYRHNIRVI SKKTGGRKIC LVVKANAYGH GSVKMAKVGI EAGAQALGVA 70 80 90 100 110 120 TVDEALELRE AGIAAPIFLF TVADVSEVPQ LVRFDIIPFV SDLAYIKQIE REAQNQEKVA 130 140 150 160 170 180 MVHLKVDTGM GRLGCRPEEA LSLASFVGNS KNLMMGGLCT HFSLSDISDR AYTLLQINRL 190 200 210 220 230 240 NLLVDTLRSQ HIPYGLVHAA NTGAIIQYPE AYYDMVRPGL GIFGYPPDLI HMGRDRADLR 250 260 270 280 290 300 PVLSMETKIG LIKTIKKGES VSYGRTFVAE NDTHIGVVAA GFCDGYPRSL SNKGFVTIKG 310 320 330 340 350 360 KHYPVIGMVC MDQLIVDLGR DLQVDPDDTV VLLGHGRNEP TMVDLTQRGN IIVNEVICRI 370 PARVPKVYIN E

References

[1]

"Complete genome sequence of Spirochaeta smaragdinae type strain (SEBR 4228)." Mavromatis K., Yasawong M., Chertkov O., Lapidus A., Lucas S., Nolan M., Glavina Del Rio T., Tice H., Cheng J., Pitluck S., Liolios K., Ivanova N., Tapia R., Han C., Bruce D., Goodwin L., Pati A., Chen A. , Palaniappan K., Land M., Hauser L., Chang Y., Jeffries C., Detter J., Rohde M., Brambilla E., Spring S., Goker M., Sikorski J., Woyke T., Bristow J., Eisen J., Markowitz V., Hugenholtz P., Klenk H., Kyrpides N. Stand. Genomic Sci. 3:136-144(2010) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 11293 / JCM 15392 / SEBR 4228.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002116 Genomic DNA. Translation: ADK80482.1.
RefSeq	YP_003803076.1. NC_014364.1.
3D structure databases
ProteinModelPortal	E1R460.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADK80482; ADK80482; Spirs_1355.
GeneID	9489444.
KEGG	ssm:Spirs_1355.
PATRIC	42526662. VBISpiSma89994_1399.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000031444.
KO	K01775.
OMA	HQLETAV.
Enzyme and pathway databases
UniPathway	UPA00042; UER00497.
Family and domain databases
Gene3D	2.40.37.10. 1 hit.
HAMAP	MF_01201. Ala_racemase.
InterPro	IPR000821. Ala_racemase. IPR009006. Ala_racemase/Decarboxylase_C. IPR011079. Ala_racemase_C. IPR001608. Ala_racemase_N. IPR020622. Ala_racemase_pyridoxalP-BS. [Graphical view]
Pfam	PF00842. Ala_racemase_C. 1 hit. PF01168. Ala_racemase_N. 1 hit. [Graphical view]
PRINTS	PR00992. ALARACEMASE.
SMART	SM01005. Ala_racemase_C. 1 hit. [Graphical view]
SUPFAM	SSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMs	TIGR00492. alr. 1 hit.
PROSITE	PS00395. ALANINE_RACEMASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

E1R460_SPISS

Accession

Primary (citable) accession number: E1R460

Entry history

Integrated into UniProtKB/TrEMBL:	November 30, 2010
Last sequence update:	November 30, 2010
Last modified:	May 1, 2013
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)