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E1R460 (E1R460_SPISS) Unreviewed, UniProtKB/TrEMBL

Last modified March 19, 2014. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length371 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. RuleBase RU004247 HAMAP-Rule MF_01201 SAAS SAAS009006

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site341Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2631Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1321Substrate By similarity HAMAP-Rule MF_01201
Binding site3111Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue341N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
E1R460 [UniParc].

Last modified November 30, 2010. Version 1.
Checksum: 4C8EB89F068EDA6F

FASTA37140,768
        10         20         30         40         50         60 
MRPTKARIDL DLYRHNIRVI SKKTGGRKIC LVVKANAYGH GSVKMAKVGI EAGAQALGVA 

        70         80         90        100        110        120 
TVDEALELRE AGIAAPIFLF TVADVSEVPQ LVRFDIIPFV SDLAYIKQIE REAQNQEKVA 

       130        140        150        160        170        180 
MVHLKVDTGM GRLGCRPEEA LSLASFVGNS KNLMMGGLCT HFSLSDISDR AYTLLQINRL 

       190        200        210        220        230        240 
NLLVDTLRSQ HIPYGLVHAA NTGAIIQYPE AYYDMVRPGL GIFGYPPDLI HMGRDRADLR 

       250        260        270        280        290        300 
PVLSMETKIG LIKTIKKGES VSYGRTFVAE NDTHIGVVAA GFCDGYPRSL SNKGFVTIKG 

       310        320        330        340        350        360 
KHYPVIGMVC MDQLIVDLGR DLQVDPDDTV VLLGHGRNEP TMVDLTQRGN IIVNEVICRI 

       370 
PARVPKVYIN E 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002116 Genomic DNA. Translation: ADK80482.1.
RefSeqYP_003803076.1. NC_014364.1.

3D structure databases

ProteinModelPortalE1R460.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADK80482; ADK80482; Spirs_1355.
GeneID9489444.
KEGGssm:Spirs_1355.
PATRIC42526662. VBISpiSma89994_1399.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000031444.
KOK01775.
OMASVELWGD.

Enzyme and pathway databases

BioCycSSMA573413:GI0C-1372-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE1R460_SPISS
AccessionPrimary (citable) accession number: E1R460
Entry history
Integrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: March 19, 2014
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)