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Protein

Thymidine kinase

Gene

Olsu_1242

Organism
Olsenella uli (strain ATCC 49627 / DSM 7084 / CIP 109912 / JCM 12494 / NCIMB 702895 / VPI D76D-27C) (Lactobacillus uli)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei86Proton acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseUniRule annotationImported, Transferase
Biological processDNA synthesisUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Ordered Locus Names:Olsu_1242Imported
OrganismiOlsenella uli (strain ATCC 49627 / DSM 7084 / CIP 109912 / JCM 12494 / NCIMB 702895 / VPI D76D-27C) (Lactobacillus uli)Imported
Taxonomic identifieri633147 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCoriobacteriiaCoriobacterialesAtopobiaceaeOlsenella
Proteomesi
  • UP000000333 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi633147.Olsu_1242.

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107W53. Bacteria.
COG1435. LUCA.
HOGENOMiHOG000076391.
KOiK00857.
OMAiRATHNAR.
OrthoDBiPOG091H0659.

Family and domain databases

InterProiView protein in InterPro
IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiView protein in Pfam
PF00265. TK. 1 hit.
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

E1QW45-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKLYYIHGA MNCGKSTNLL QVAHNYEERG MRVLLMKPST DTKGDASIMS
60 70 80 90 100
RLGVTRRVDV LIRPGDRMGD LVAPHLAHVG CVLIDEAQFL TPRQAEELHE
110 120 130 140 150
LVHTRHVPCM CYGLKIDFRA AGFPGSSRLL ELADEIRELR TICQCGRRAT
160 170 180 190 200
MNLRLVNGVA TFSGSQVEVD DQGDIRYVSV CGDCFYKIRN GEMRYDYGEA
210
MGKASPTDVT DPDDPA
Length:216
Mass (Da):24,026
Last modified:November 30, 2010 - v1
Checksum:iFBF91BC9ADB68968
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002106 Genomic DNA. Translation: ADK68348.1.

Genome annotation databases

EnsemblBacteriaiADK68348; ADK68348; Olsu_1242.
KEGGiols:Olsu_1242.
PATRICifig|633147.7.peg.290.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiE1QW45_OLSUV
AccessioniPrimary (citable) accession number: E1QW45
Entry historyiIntegrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: July 5, 2017
This is version 40 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported