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E1QTB1 (E1QTB1_VULDI) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein attributes

Sequence length607 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair By similarity. HAMAP-Rule MF_00407

Catalytic activity

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). HAMAP-Rule MF_00407

Cofactor

Divalent metal cations By similarity. HAMAP-Rule MF_00407

Sequence similarities

Belongs to the ATP-dependent DNA ligase family. HAMAP-Rule MF_00407 RuleBase RU004196

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2671N6-AMP-lysine intermediate By similarity HAMAP-Rule MF_00407
Binding site2651ATP By similarity HAMAP-Rule MF_00407
Binding site2721ATP By similarity HAMAP-Rule MF_00407
Binding site2881ATP By similarity HAMAP-Rule MF_00407
Binding site3181ATP By similarity HAMAP-Rule MF_00407
Binding site3581ATP By similarity HAMAP-Rule MF_00407
Binding site4351ATP By similarity HAMAP-Rule MF_00407
Binding site4411ATP By similarity HAMAP-Rule MF_00407

Sequences

Sequence LengthMass (Da)Tools
E1QTB1 [UniParc].

Last modified November 30, 2010. Version 1.
Checksum: 5D609492566379E6

FASTA60768,274
        10         20         30         40         50         60 
MSTGSNDIKF IDVVKALESI EATTQRTVMA KLLSSLLKKT PPNVIDKVIY FILGQLRPDW 

        70         80         90        100        110        120 
EGVELGVAEK LTFRAIANAT GAPIKQIEDL YKRLGDVGET ARRIMSSKPQ QGGGKSILEF 

       130        140        150        160        170        180 
FGGGGGEELT MGKVYDTLMS IARASGEGAQ DTKVKLLTYL FSRAKPEEAK YIARFVIGRL 

       190        200        210        220        230        240 
RLGVADMTIL DALSDAYKVP REALERAYHI YPDLGYIAKM VAQEGQNALA KIHVTPGVPI 

       250        260        270        280        290        300 
QPMLAERLST STEILAKLGG VAMVEYKYDG ERAQIHKTRD GEIRIFSRRL ENITHAYPDV 

       310        320        330        340        350        360 
AEYVKEAIDA KEYIVEGEIV AIDPDTGEFR PFQELMHRKR KHDIKEAMKE YPVNIFLFDI 

       370        380        390        400        410        420 
MYIDGQDLTN LPLIDRKRKL LEVLKPSEYV HLATWRIIND AEELDKFFHE AISDGCEGVM 

       430        440        450        460        470        480 
CKSIKADSIY EMGARGWLWI KYKRDYRSEL TDTLDLVVVG AFWGRGKRAG TYGALLIAAY 

       490        500        510        520        530        540 
DPKTDQFYTV SKVGSGFTDE DLVKLKQMLD PYRIPHKHPR VVSKMEPDVW FVPAVVLEII 

       550        560        570        580        590        600 
GAEITLSPLH TCCMGAIRPG VGLAIRFPRF TGRYRTDKSP EQATTVDEIL EMYKEQKKVK 


IEEGANP 

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002100 Genomic DNA. Translation: ADN50904.1.
RefSeqYP_003901955.1. NC_014537.1.

3D structure databases

ProteinModelPortalE1QTB1.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADN50904; ADN50904; Vdis_1519.
GeneID9752456.
KEGGvdi:Vdis_1519.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000036008.
KOK10747.
OMAMVKMLEG.

Enzyme and pathway databases

BioCycVDIS572478:GHT7-1544-MONOMER.

Family and domain databases

Gene3D1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
HAMAPMF_00407. DNA_ligase.
InterProIPR022865. DNA_ligae_ATP-dep_bac/arc.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsTIGR00574. dnl1. 1 hit.
PROSITEPS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE1QTB1_VULDI
AccessionPrimary (citable) accession number: E1QTB1
Entry history
Integrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: June 11, 2014
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)