Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

E1QTB1

- E1QTB1_VULDI

UniProt

E1QTB1 - E1QTB1_VULDI

Protein

DNA ligase

Gene

lig

Organism
Vulcanisaeta distributa (strain DSM 14429 / JCM 11212 / NBRC 100878 / IC-017)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 26 (01 Oct 2014)
      Sequence version 1 (30 Nov 2010)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.UniRule annotation

    Catalytic activityi

    ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

    Cofactori

    Divalent metal cations.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei265 – 2651ATPUniRule annotation
    Active sitei267 – 2671N6-AMP-lysine intermediateUniRule annotation
    Binding sitei272 – 2721ATPUniRule annotation
    Binding sitei288 – 2881ATPUniRule annotation
    Binding sitei318 – 3181ATPUniRule annotation
    Binding sitei358 – 3581ATPUniRule annotation
    Binding sitei435 – 4351ATPUniRule annotation
    Binding sitei441 – 4411ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. DNA binding Source: InterPro
    3. DNA ligase (ATP) activity Source: UniProtKB-HAMAP
    4. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. cell cycle Source: UniProtKB-KW
    2. cell division Source: UniProtKB-KW
    3. DNA ligation involved in DNA repair Source: InterPro
    4. DNA recombination Source: UniProtKB-HAMAP
    5. DNA replication Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    LigaseUniRule annotationImported

    Keywords - Biological processi

    Cell cycle, Cell divisionUniRule annotation, DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Metal-bindingUniRule annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciVDIS572478:GHT7-1544-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
    Alternative name(s):
    Polydeoxyribonucleotide synthase [ATP]UniRule annotation
    Gene namesi
    Name:ligUniRule annotation
    Ordered Locus Names:Vdis_1519Imported
    OrganismiVulcanisaeta distributa (strain DSM 14429 / JCM 11212 / NBRC 100878 / IC-017)Imported
    Taxonomic identifieri572478 [NCBI]
    Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiThermoprotealesThermoproteaceaeVulcanisaeta
    ProteomesiUP000006681: Chromosome

    Structurei

    3D structure databases

    ProteinModelPortaliE1QTB1.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ATP-dependent DNA ligase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000036008.
    KOiK10747.
    OMAiMVKMLEG.

    Family and domain databases

    Gene3Di1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    HAMAPiMF_00407. DNA_ligase.
    InterProiIPR022865. DNA_ligae_ATP-dep_bac/arc.
    IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view]
    PfamiPF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsiTIGR00574. dnl1. 1 hit.
    PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E1QTB1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSTGSNDIKF IDVVKALESI EATTQRTVMA KLLSSLLKKT PPNVIDKVIY    50
    FILGQLRPDW EGVELGVAEK LTFRAIANAT GAPIKQIEDL YKRLGDVGET 100
    ARRIMSSKPQ QGGGKSILEF FGGGGGEELT MGKVYDTLMS IARASGEGAQ 150
    DTKVKLLTYL FSRAKPEEAK YIARFVIGRL RLGVADMTIL DALSDAYKVP 200
    REALERAYHI YPDLGYIAKM VAQEGQNALA KIHVTPGVPI QPMLAERLST 250
    STEILAKLGG VAMVEYKYDG ERAQIHKTRD GEIRIFSRRL ENITHAYPDV 300
    AEYVKEAIDA KEYIVEGEIV AIDPDTGEFR PFQELMHRKR KHDIKEAMKE 350
    YPVNIFLFDI MYIDGQDLTN LPLIDRKRKL LEVLKPSEYV HLATWRIIND 400
    AEELDKFFHE AISDGCEGVM CKSIKADSIY EMGARGWLWI KYKRDYRSEL 450
    TDTLDLVVVG AFWGRGKRAG TYGALLIAAY DPKTDQFYTV SKVGSGFTDE 500
    DLVKLKQMLD PYRIPHKHPR VVSKMEPDVW FVPAVVLEII GAEITLSPLH 550
    TCCMGAIRPG VGLAIRFPRF TGRYRTDKSP EQATTVDEIL EMYKEQKKVK 600
    IEEGANP 607
    Length:607
    Mass (Da):68,274
    Last modified:November 30, 2010 - v1
    Checksum:i5D609492566379E6
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002100 Genomic DNA. Translation: ADN50904.1.
    RefSeqiWP_013336629.1. NC_014537.1.
    YP_003901955.1. NC_014537.1.

    Genome annotation databases

    EnsemblBacteriaiADN50904; ADN50904; Vdis_1519.
    GeneIDi9752456.
    KEGGivdi:Vdis_1519.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002100 Genomic DNA. Translation: ADN50904.1 .
    RefSeqi WP_013336629.1. NC_014537.1.
    YP_003901955.1. NC_014537.1.

    3D structure databases

    ProteinModelPortali E1QTB1.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADN50904 ; ADN50904 ; Vdis_1519 .
    GeneIDi 9752456.
    KEGGi vdi:Vdis_1519.

    Phylogenomic databases

    HOGENOMi HOG000036008.
    KOi K10747.
    OMAi MVKMLEG.

    Enzyme and pathway databases

    BioCyci VDIS572478:GHT7-1544-MONOMER.

    Family and domain databases

    Gene3Di 1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    HAMAPi MF_00407. DNA_ligase.
    InterProi IPR022865. DNA_ligae_ATP-dep_bac/arc.
    IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view ]
    Pfami PF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsi TIGR00574. dnl1. 1 hit.
    PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 14429 / JCM 11212 / NBRC 100878 / IC-017Imported.

    Entry informationi

    Entry nameiE1QTB1_VULDI
    AccessioniPrimary (citable) accession number: E1QTB1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 30, 2010
    Last sequence update: November 30, 2010
    Last modified: October 1, 2014
    This is version 26 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3