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Protein

Phosphoenolpyruvate carboxylase

Gene

ppcA

Organism
Vulcanisaeta distributa (strain DSM 14429 / JCM 11212 / NBRC 100878 / IC-017)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Mg2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationImported

Keywords - Biological processi

Carbon dioxide fixationUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotation, PyruvateImported

Enzyme and pathway databases

BioCyciVDIS572478:GHT7-691-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcAUniRule annotation
Ordered Locus Names:Vdis_0679Imported
OrganismiVulcanisaeta distributa (strain DSM 14429 / JCM 11212 / NBRC 100878 / IC-017)Imported
Taxonomic identifieri572478 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiThermoprotealesThermoproteaceaeVulcanisaeta
ProteomesiUP000006681 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi572478.Vdis_0679.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 2 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000038601.
KOiK01595.
OMAiQSSFKYD.

Family and domain databases

HAMAPiMF_01904. PEPcase_type2.
InterProiIPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF14010. PEPcase_2. 1 hit.
[Graphical view]
PIRSFiPIRSF006677. UCP006677. 1 hit.
SUPFAMiSSF51621. SSF51621. 1 hit.
TIGRFAMsiTIGR02751. PEPCase_arch. 1 hit.

Sequencei

Sequence statusi: Complete.

E1QNA4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLIPRSMCT QHPDNARVPD WARDSIIQGD DEVHEAYLAY SLYGCHEVMW
60 70 80 90 100
DFEGKDVDIY VVRKLLSRYP GFFRDHVLGR DVYLTLRLPN PWAETAEKKL
110 120 130 140 150
FSQALELIPT AYDVAREFYG TDDINGVFQV ILPLTSRAEE LVFTYRYYER
160 170 180 190 200
VVAGKAFIEL TPGVRVMDVL GSVRPSTIDV IPLIEDLGSM LNVGKIIIGY
210 220 230 240 250
WRVVRPSYLR IFIARSDPAM NYGLIPAVLM AKIALNKALN LGRELGLEIY
260 270 280 290 300
PIIGVGPTPF RGNLTPHNVD NVVREYPCVH TFTVQSAFRY DYPEGEVINA
310 320 330 340 350
ISKLNNRKPD GGCDIPNHGV LINVINKYVV NYQREIEGLA NVINRVSNYV
360 370 380 390 400
PRRRARKLHI GLFGYSRGFR GVVLPRAITF VAALYSLGIP PEVLGVSTIN
410 420 430 440 450
ELSDREYSAL SEAYVNLRHD LSMAARYVCH ECLDMLTKLG NSFGITREVI
460 470 480 490 500
DMVKRDIKTL EEMGIKTGPS DYDSRKHELL TQLFINSLVE GKEDDAVKYM
510
VEMALIRHAI G
Length:511
Mass (Da):57,856
Last modified:November 30, 2010 - v1
Checksum:iD854F92EF3066C49
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002100 Genomic DNA. Translation: ADN50074.1.
RefSeqiWP_013335799.1. NC_014537.1.
YP_003901125.1. NC_014537.1.

Genome annotation databases

EnsemblBacteriaiADN50074; ADN50074; Vdis_0679.
GeneIDi9751603.
KEGGivdi:Vdis_0679.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002100 Genomic DNA. Translation: ADN50074.1.
RefSeqiWP_013335799.1. NC_014537.1.
YP_003901125.1. NC_014537.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi572478.Vdis_0679.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADN50074; ADN50074; Vdis_0679.
GeneIDi9751603.
KEGGivdi:Vdis_0679.

Phylogenomic databases

HOGENOMiHOG000038601.
KOiK01595.
OMAiQSSFKYD.

Enzyme and pathway databases

BioCyciVDIS572478:GHT7-691-MONOMER.

Family and domain databases

HAMAPiMF_01904. PEPcase_type2.
InterProiIPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF14010. PEPcase_2. 1 hit.
[Graphical view]
PIRSFiPIRSF006677. UCP006677. 1 hit.
SUPFAMiSSF51621. SSF51621. 1 hit.
TIGRFAMsiTIGR02751. PEPCase_arch. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 14429 / JCM 11212 / NBRC 100878 / IC-017Imported.

Entry informationi

Entry nameiE1QNA4_VULDI
AccessioniPrimary (citable) accession number: E1QNA4
Entry historyi
Integrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: June 24, 2015
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.