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E1Q3R6 (E1Q3R6_HELPP) Unreviewed, UniProtKB/TrEMBL

Last modified May 14, 2014. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Isocitrate dehydrogenase [NADP] RuleBase RU004446

EC=1.1.1.42 RuleBase RU004446
Gene names
Ordered Locus Names:HPPC_00125 EMBL ADO06288.1
OrganismHelicobacter pylori (strain PeCan4) [Complete proteome] [HAMAP] EMBL ADO06288.1
Taxonomic identifier765963 [NCBI]
Taxonomic lineageBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter

Protein attributes

Sequence length425 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH. RuleBase RU004446

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. RuleBase RU004446

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family.

Sequences

Sequence LengthMass (Da)Tools
E1Q3R6 [UniParc].

Last modified November 30, 2010. Version 1.
Checksum: C7EE417A1CCF10EB

FASTA42547,522
        10         20         30         40         50         60 
MAYNPKILQK PKEGEEITIK DNKLHVPNHP IIPFIEGDGI GSDITPAMIK VVDSAVQKAY 

        70         80         90        100        110        120 
KGEKKIAWYE VFVGEKCYQK FKDHKELSPE EQWLLPDTIE AINHYKVSIK GPLTTPIGEG 

       130        140        150        160        170        180 
FRSLNVALRQ KMDLYVCLRP VRWYGSPSPV KEPQKVDMVI FRENSEDIYA GIEWQEGSTE 

       190        200        210        220        230        240 
AKKLIHFLQN ELKVKKIRFP ESSGIGVKPI SKEGTERLVR KAIEYAIDND KPSVTFVHKG 

       250        260        270        280        290        300 
NIMKYTEGAF MKWGYALAQK EFNAQVIDKG PWCSLKNPKT GKEIIIKDMI ADAFLQQILL 

       310        320        330        340        350        360 
RPSEYSVIAT MNLNGDYISD ALAAMVGGIG IAPGANLNDT VGMFEATHGT APKYAGLDKV 

       370        380        390        400        410        420 
NPGSIILSAE MMLRHMGWVE AADLIVSAME KAIKSKKVTY DFARLMDGAK EVKCSEFASV 


MIENM 

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References

[1]"Complete genome sequence of Helicobacter pylori strain PeCan4."
Kersulyte D., Vasquez J., Gilman R.H., Berg D.E.
Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PeCan4.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002074 Genomic DNA. Translation: ADO06288.1.
RefSeqYP_003926338.1. NC_014555.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADO06288; ADO06288; HPPC_00125.
GeneID9785108.
KEGGhpc:HPPC_00125.
PATRIC42490117. VBIHelPyl173672_0029.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000021113.
KOK00031.
OMACLRPIRY.

Enzyme and pathway databases

BioCycHPYL765963:GH9T-28-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 1 hit.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR00183. prok_nadp_idh. 1 hit.
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE1Q3R6_HELPP
AccessionPrimary (citable) accession number: E1Q3R6
Entry history
Integrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: May 14, 2014
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)