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E1Q345

- E1Q345_HELPP

UniProt

E1Q345 - E1Q345_HELPP

Protein

Adenylosuccinate lyase

Gene

HPPC_05405

Organism
Helicobacter pylori (strain PeCan4)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 27 (01 Oct 2014)
      Sequence version 1 (30 Nov 2010)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate = fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.UniRule annotation
    N(6)-(1,2-dicarboxyethyl)AMP = fumarate + AMP.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity Source: UniProtKB-EC
    2. N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity Source: UniProtKB-EC

    GO - Biological processi

    1. purine ribonucleotide biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    LyaseUniRule annotationImported

    Keywords - Biological processi

    Purine biosynthesisUniRule annotation

    Enzyme and pathway databases

    BioCyciHPYL765963:GH9T-1057-MONOMER.
    UniPathwayiUPA00074; UER00132.
    UPA00075; UER00336.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Adenylosuccinate lyaseUniRule annotation (EC:4.3.2.2UniRule annotation)
    Short name:
    ASLUniRule annotation
    Alternative name(s):
    AdenylosuccinaseUniRule annotation
    Gene namesi
    Ordered Locus Names:HPPC_05405Imported
    OrganismiHelicobacter pylori (strain PeCan4)Imported
    Taxonomic identifieri765963 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
    ProteomesiUP000006863: Chromosome

    Structurei

    3D structure databases

    ProteinModelPortaliE1Q345.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000033912.
    KOiK01756.
    OMAiRNMGSTF.

    Family and domain databases

    Gene3Di1.10.275.10. 1 hit.
    InterProiIPR019468. AdenyloSucc_lyase_C.
    IPR024083. Fumarase/histidase_N.
    IPR020557. Fumarate_lyase_CS.
    IPR000362. Fumarate_lyase_fam.
    IPR022761. Fumarate_lyase_N.
    IPR008948. L-Aspartase-like.
    IPR004769. Pur_lyase.
    [Graphical view]
    PANTHERiPTHR11444. PTHR11444. 1 hit.
    PfamiPF10397. ADSL_C. 1 hit.
    PF00206. Lyase_1. 1 hit.
    [Graphical view]
    PRINTSiPR00149. FUMRATELYASE.
    SMARTiSM00998. ADSL_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF48557. SSF48557. 1 hit.
    TIGRFAMsiTIGR00928. purB. 1 hit.
    PROSITEiPS00163. FUMARATE_LYASES. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E1Q345-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLERYANEEM KALWNEQTKF ETYLEVEKAV VRAWNKLGQI QDSDCEKICS    50
    KAAFNLERIK EIEKTTKHDL IAFTTCVAES LGEESRFFHY GITSSDCIDT 100
    AMALLMTKSL KLIQKGVKNL YETLKNRALE HKDTLMVGRS HGVFGEPITF 150
    GLVLALFADE IKRHLKALDL TMEFISVGAI SGAMGNFAHA PLELEELACE 200
    FLGLKTANIS NQVIQRDRYA RLACDLALLA SSCEKIAVNI RHLQRSEVYE 250
    VEEAFSAGQK GSSAMPHKRN PILSENITGL CRVIRSFTTP MLENVALWHE 300
    RDMSHSSVER FALPDLFITS DFMLSRLNSV IENLVVYPKN MLKNLALSGG 350
    LVFSQRVLLE LPKKGLSREE SYSIVQENAM KIWEILQQGA FKNADENLFL 400
    NALLNDERLK KYLSEDEIKA CFDYSYYTKN VGAIFKRVFG 440
    Length:440
    Mass (Da):49,901
    Last modified:November 30, 2010 - v1
    Checksum:iCEA05672E00044B3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002074 Genomic DNA. Translation: ADO07293.1.
    RefSeqiYP_003927343.1. NC_014555.1.

    Genome annotation databases

    EnsemblBacteriaiADO07293; ADO07293; HPPC_05405.
    GeneIDi9786137.
    KEGGihpc:HPPC_05405.
    PATRICi42492309. VBIHelPyl173672_1099.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002074 Genomic DNA. Translation: ADO07293.1 .
    RefSeqi YP_003927343.1. NC_014555.1.

    3D structure databases

    ProteinModelPortali E1Q345.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADO07293 ; ADO07293 ; HPPC_05405 .
    GeneIDi 9786137.
    KEGGi hpc:HPPC_05405.
    PATRICi 42492309. VBIHelPyl173672_1099.

    Phylogenomic databases

    HOGENOMi HOG000033912.
    KOi K01756.
    OMAi RNMGSTF.

    Enzyme and pathway databases

    UniPathwayi UPA00074 ; UER00132 .
    UPA00075 ; UER00336 .
    BioCyci HPYL765963:GH9T-1057-MONOMER.

    Family and domain databases

    Gene3Di 1.10.275.10. 1 hit.
    InterProi IPR019468. AdenyloSucc_lyase_C.
    IPR024083. Fumarase/histidase_N.
    IPR020557. Fumarate_lyase_CS.
    IPR000362. Fumarate_lyase_fam.
    IPR022761. Fumarate_lyase_N.
    IPR008948. L-Aspartase-like.
    IPR004769. Pur_lyase.
    [Graphical view ]
    PANTHERi PTHR11444. PTHR11444. 1 hit.
    Pfami PF10397. ADSL_C. 1 hit.
    PF00206. Lyase_1. 1 hit.
    [Graphical view ]
    PRINTSi PR00149. FUMRATELYASE.
    SMARTi SM00998. ADSL_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48557. SSF48557. 1 hit.
    TIGRFAMsi TIGR00928. purB. 1 hit.
    PROSITEi PS00163. FUMARATE_LYASES. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of Helicobacter pylori strain PeCan4."
      Kersulyte D., Vasquez J., Gilman R.H., Berg D.E.
      Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: PeCan4Imported.

    Entry informationi

    Entry nameiE1Q345_HELPP
    AccessioniPrimary (citable) accession number: E1Q345
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 30, 2010
    Last sequence update: November 30, 2010
    Last modified: October 1, 2014
    This is version 27 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3