Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

E1Q345

- E1Q345_HELPP

UniProt

E1Q345 - E1Q345_HELPP

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Adenylosuccinate lyase

Gene

HPPC_05405

Organism
Helicobacter pylori (strain PeCan4)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate = fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.UniRule annotation
N(6)-(1,2-dicarboxyethyl)AMP = fumarate + AMP.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity Source: UniProtKB-EC
  2. N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity Source: UniProtKB-EC

GO - Biological processi

  1. 'de novo' AMP biosynthetic process Source: UniProtKB-UniPathway
  2. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationImported

Keywords - Biological processi

Purine biosynthesisUniRule annotation

Enzyme and pathway databases

BioCyciHPYL765963:GH9T-1057-MONOMER.
UniPathwayiUPA00074; UER00132.
UPA00075; UER00336.

Names & Taxonomyi

Protein namesi
Recommended name:
Adenylosuccinate lyaseUniRule annotation (EC:4.3.2.2UniRule annotation)
Short name:
ASLUniRule annotation
Alternative name(s):
AdenylosuccinaseUniRule annotation
Gene namesi
Ordered Locus Names:HPPC_05405Imported
OrganismiHelicobacter pylori (strain PeCan4)Imported
Taxonomic identifieri765963 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
ProteomesiUP000006863: Chromosome

Structurei

3D structure databases

ProteinModelPortaliE1Q345.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000033912.
KOiK01756.
OMAiRNMGSTF.

Family and domain databases

Gene3Di1.10.275.10. 1 hit.
InterProiIPR019468. AdenyloSucc_lyase_C.
IPR024083. Fumarase/histidase_N.
IPR020557. Fumarate_lyase_CS.
IPR000362. Fumarate_lyase_fam.
IPR022761. Fumarate_lyase_N.
IPR008948. L-Aspartase-like.
IPR004769. Pur_lyase.
[Graphical view]
PANTHERiPTHR11444. PTHR11444. 1 hit.
PfamiPF10397. ADSL_C. 1 hit.
PF00206. Lyase_1. 1 hit.
[Graphical view]
PRINTSiPR00149. FUMRATELYASE.
SMARTiSM00998. ADSL_C. 1 hit.
[Graphical view]
SUPFAMiSSF48557. SSF48557. 1 hit.
TIGRFAMsiTIGR00928. purB. 1 hit.
PROSITEiPS00163. FUMARATE_LYASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E1Q345 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLERYANEEM KALWNEQTKF ETYLEVEKAV VRAWNKLGQI QDSDCEKICS
60 70 80 90 100
KAAFNLERIK EIEKTTKHDL IAFTTCVAES LGEESRFFHY GITSSDCIDT
110 120 130 140 150
AMALLMTKSL KLIQKGVKNL YETLKNRALE HKDTLMVGRS HGVFGEPITF
160 170 180 190 200
GLVLALFADE IKRHLKALDL TMEFISVGAI SGAMGNFAHA PLELEELACE
210 220 230 240 250
FLGLKTANIS NQVIQRDRYA RLACDLALLA SSCEKIAVNI RHLQRSEVYE
260 270 280 290 300
VEEAFSAGQK GSSAMPHKRN PILSENITGL CRVIRSFTTP MLENVALWHE
310 320 330 340 350
RDMSHSSVER FALPDLFITS DFMLSRLNSV IENLVVYPKN MLKNLALSGG
360 370 380 390 400
LVFSQRVLLE LPKKGLSREE SYSIVQENAM KIWEILQQGA FKNADENLFL
410 420 430 440
NALLNDERLK KYLSEDEIKA CFDYSYYTKN VGAIFKRVFG
Length:440
Mass (Da):49,901
Last modified:November 30, 2010 - v1
Checksum:iCEA05672E00044B3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002074 Genomic DNA. Translation: ADO07293.1.
RefSeqiWP_000893889.1. NC_014555.1.
YP_003927343.1. NC_014555.1.

Genome annotation databases

EnsemblBacteriaiADO07293; ADO07293; HPPC_05405.
GeneIDi9786137.
KEGGihpc:HPPC_05405.
PATRICi42492309. VBIHelPyl173672_1099.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002074 Genomic DNA. Translation: ADO07293.1 .
RefSeqi WP_000893889.1. NC_014555.1.
YP_003927343.1. NC_014555.1.

3D structure databases

ProteinModelPortali E1Q345.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADO07293 ; ADO07293 ; HPPC_05405 .
GeneIDi 9786137.
KEGGi hpc:HPPC_05405.
PATRICi 42492309. VBIHelPyl173672_1099.

Phylogenomic databases

HOGENOMi HOG000033912.
KOi K01756.
OMAi RNMGSTF.

Enzyme and pathway databases

UniPathwayi UPA00074 ; UER00132 .
UPA00075 ; UER00336 .
BioCyci HPYL765963:GH9T-1057-MONOMER.

Family and domain databases

Gene3Di 1.10.275.10. 1 hit.
InterProi IPR019468. AdenyloSucc_lyase_C.
IPR024083. Fumarase/histidase_N.
IPR020557. Fumarate_lyase_CS.
IPR000362. Fumarate_lyase_fam.
IPR022761. Fumarate_lyase_N.
IPR008948. L-Aspartase-like.
IPR004769. Pur_lyase.
[Graphical view ]
PANTHERi PTHR11444. PTHR11444. 1 hit.
Pfami PF10397. ADSL_C. 1 hit.
PF00206. Lyase_1. 1 hit.
[Graphical view ]
PRINTSi PR00149. FUMRATELYASE.
SMARTi SM00998. ADSL_C. 1 hit.
[Graphical view ]
SUPFAMi SSF48557. SSF48557. 1 hit.
TIGRFAMsi TIGR00928. purB. 1 hit.
PROSITEi PS00163. FUMARATE_LYASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of Helicobacter pylori strain PeCan4."
    Kersulyte D., Vasquez J., Gilman R.H., Berg D.E.
    Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PeCan4Imported.

Entry informationi

Entry nameiE1Q345_HELPP
AccessioniPrimary (citable) accession number: E1Q345
Entry historyi
Integrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: October 29, 2014
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3