E1Q049 (E1Q049_HELPM) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Alanine racemase RuleBase RU000608
EC=5.1.1.1 RuleBase RU000608

Gene names

Name:	alr
Ordered Locus Names:	HPSJM_04795 EMBL ADO02540.1

Organism

Helicobacter pylori (strain SJM180) [Complete proteome] [HAMAP]

Taxonomic identifier

765962 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › delta/epsilon subdivisions › Epsilonproteobacteria › Campylobacterales › Helicobacteraceae › Helicobacter › Helicobacter pylori

Protein attributes

Sequence length	377 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-alanine = D-alanine. RuleBase RU000608 SAAS SAAS020622
Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000608 SAAS SAAS020622
Pathway	Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. SAAS SAAS020622
Sequence similarities	Belongs to the alanine racemase family. RuleBase RU004188

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU000608 SAAS SAAS020622
Molecular function	Isomerase SAAS SAAS020622 RuleBase RU000608
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	D-alanine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	alanine racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E1Q049 [UniParc]. Last modified November 30, 2010. Version 1. Checksum: 7BF562FA3CF7EBEC	FASTA	377	41,839
	10 20 30 40 50 60 MLKRASFVEV DTASLRHNFH AVKSIVPKDA CIMAVVKANA YGAGAIKASE IFLQEGANYL 70 80 90 100 110 120 GVATLDEALE LRSHFSKTPI LILGYSPNAN ASMLVDNDLS AMVFSLEQAE VFSQMALKSQ 130 140 150 160 170 180 KRLKVHIKID TGMHRLGLEP NFKSIETIKK IRALKGLEVE GIFTHLSNAD AKIKTHAKNQ 190 200 210 220 230 240 MKAFNAFLEQ LLDQKIEFQY RHAYNSAGIL SLCNGNENRL LNLYRPGIML YGFYPSNEMK 250 260 270 280 290 300 ESCPTILKNV ISLKARIVQI RSVKKGEFIG YGEHFYTNEE TLVGVLALGY ADGLMRALGN 310 320 330 340 350 360 RIQVAINNQL APLIGKVCMD QCFVKLNDIE AKEGDEVILF GDKSAKANDA SEIAALLNTI 370 PYETISTLSK RLERVYV

References

[1]	"Complete genome sequence of Helicobacter pylori strain SJM180." Kersulyte D., Velapatino B., Gilman R.H., Berg D.E. Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SJM180.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002073 Genomic DNA. Translation: ADO02540.1.
RefSeq	YP_003928857.1. NC_014560.1.
3D structure databases
ProteinModelPortal	E1Q049.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADO02540; ADO02540; HPSJM_04795.
GeneID	9787677.
KEGG	hpm:HPSJM_04795.
PATRIC	42495388. VBIHelPyl169273_0955.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000031444.
KO	K01775.
Enzyme and pathway databases
BioCyc	HPYL765962:GH29-944-MONOMER.
UniPathway	UPA00042; UER00497.
Family and domain databases
Gene3D	2.40.37.10. 1 hit.
HAMAP	MF_01201. Ala_racemase.
InterPro	IPR000821. Ala_racemase. IPR009006. Ala_racemase/Decarboxylase_C. IPR011079. Ala_racemase_C. IPR001608. Ala_racemase_N. IPR020622. Ala_racemase_pyridoxalP-BS. [Graphical view]
Pfam	PF00842. Ala_racemase_C. 1 hit. PF01168. Ala_racemase_N. 1 hit. [Graphical view]
PRINTS	PR00992. ALARACEMASE.
SMART	SM01005. Ala_racemase_C. 1 hit. [Graphical view]
SUPFAM	SSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMs	TIGR00492. alr. 1 hit.
PROSITE	PS00395. ALANINE_RACEMASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

E1Q049_HELPM

Accession

Primary (citable) accession number: E1Q049

Entry history

Integrated into UniProtKB/TrEMBL:	November 30, 2010
Last sequence update:	November 30, 2010
Last modified:	May 1, 2013
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)