E1PBM8 (E1PBM8_ECOAB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Aspartokinase RuleBase RU003448
EC=2.7.2.4 RuleBase RU003448

Gene names

Name:	lysC EMBL ADN48945.1
Ordered Locus Names:	ECABU_c45470 EMBL ADN48945.1

Organism

Escherichia coli OR:K5:H- (strain ABU 83972) [Complete proteome] [HAMAP] EMBL ADN48945.1

Taxonomic identifier

655817 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	449 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + L-aspartate = ADP + 4-phospho-L-aspartate. RuleBase RU003448
Sequence similarities	Belongs to the aspartokinase family. RuleBase RU003448

Ontologies

Keywords
Molecular function	Kinase RuleBase RU003448 EMBL ADN48945.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	lysine biosynthetic process via diaminopimelate Inferred from electronic annotation. Source: InterPro
Molecular_function	amino acid binding Inferred from electronic annotation. Source: InterPro aspartate kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E1PBM8 [UniParc]. Last modified November 30, 2010. Version 1. Checksum: 94731A89240C42DB	FASTA	449	48,578
	10 20 30 40 50 60 MSEIVVSKFG GTSVADFDAM NRSADIVLSD ANVRLVVLSA SAGITNLLVA LAEGLEPGER 70 80 90 100 110 120 FEKLDAIRNI QFAILERLRY PNVIREEIER LLENITVLAE AAALATSPAL TDELVSHGEL 130 140 150 160 170 180 MSTLLFVEIL RERDVQAQWF DVRKVMRTND RFGRAEPDVA ALAELAALQL LPRLNEGLVI 190 200 210 220 230 240 TQGFIGSENK GRTTTLGRGG SDYTAALLAE ALHASRVDIW TDVPGIYTTD PRVVSAAKRI 250 260 270 280 290 300 DEIAFAEAAE MATFGAKVLH PATLLPAVRS DIPVFVGSSK DPRAGGTLVC NKTENPPLFR 310 320 330 340 350 360 ALALRRNQTL LTLHSLNMLH SRGFLAEVFG ILARHNISVD LITTSEVSVA LTLDTTGSTS 370 380 390 400 410 420 TGDTLLTQSL LMELSALCRV EVEEGLALVA LIGNDLSKAC GVGKEVFGVL EPFNIRMICY 430 440 GASSHNLCFL VPGEDAEQVV QKLHFNLFE

References

[1]

"Host imprints on bacterial genomes--rapid, divergent evolution in individual patients." Zdziarski J., Brzuszkiewicz E., Wullt B., Liesegang H., Biran D., Voigt B., Gronberg-Hernandez J., Ragnarsdottir B., Hecker M., Ron E.Z., Daniel R., Gottschalk G., Hacker J., Svanborg C., Dobrindt U. PLoS Pathog. 6:e1001078-e1001078(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ABU 83972 EMBL ADN48945.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001671 Genomic DNA. Translation: ADN48945.1.
RefSeq	YP_006108476.1. NC_017631.1.
3D structure databases
ProteinModelPortal	E1PBM8.
SMR	E1PBM8. Positions 3-449.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADN48945; ADN48945; ECABU_c45470.
GeneID	12729829.
KEGG	eab:ECABU_c45470.
PATRIC	42954125. VBIEscCol35126_4738.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000293094.
KO	K00928.
OMA	IRLICYG.
Family and domain databases
Gene3D	3.40.1160.10. 2 hits.
InterPro	IPR002912. ACT_dom. IPR001048. Asp/Glu/Uridylate_kinase. IPR005260. Asp_kin_monofn. IPR001341. Asp_kinase_dom. IPR018042. Aspartate_kinase_CS. [Graphical view]
Pfam	PF00696. AA_kinase. 1 hit. PF01842. ACT. 1 hit. [Graphical view]
PIRSF	PIRSF000726. Asp_kin. 1 hit.
SUPFAM	SSF53633. Aa_kinase. 1 hit.
TIGRFAMs	TIGR00656. asp_kin_monofn. 1 hit. TIGR00657. asp_kinases. 1 hit.
PROSITE	PS00324. ASPARTOKINASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

E1PBM8_ECOAB

Accession

Primary (citable) accession number: E1PBM8

Entry history

Integrated into UniProtKB/TrEMBL:	November 30, 2010
Last sequence update:	November 30, 2010
Last modified:	May 1, 2013
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)