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E1JJ04

- E1JJ04_DROME

UniProt

E1JJ04 - E1JJ04_DROME

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Protein
Submitted name: Dynein heavy chain at 89D, isoform C
Gene
Dhc98D, CG1842, Dmel_CG1842
Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. ATPase activity, coupled Source: FlyBase
  3. microtubule motor activity Source: InterPro

GO - Biological processi

  1. ATP catabolic process Source: GOC
  2. microtubule-based movement Source: FlyBase
Complete GO annotation...

Keywords - Molecular functioni

HydrolaseImported

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Dynein heavy chain at 89D, isoform CImported (EC:3.6.1.3Imported)
Gene namesi
Name:Dhc98DImported
ORF Names:CG1842Imported, Dmel_CG1842Imported
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000000803: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0013813. Dhc98D.

Subcellular locationi

GO - Cellular componenti

  1. dynein complex Source: InterPro
  2. microtubule associated complex Source: FlyBase
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiE1JJ04.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00750000117552.
KOiK01509.
OrthoDBiEOG7RRF64.

Family and domain databases

Gene3Di3.40.50.300. 4 hits.
InterProiIPR003593. AAA+_ATPase.
IPR026983. DHC_fam.
IPR024743. Dynein_HC_stalk.
IPR024317. Dynein_heavy_chain_D4_dom.
IPR004273. Dynein_heavy_dom.
IPR013594. Dynein_heavy_dom-1.
IPR013602. Dynein_heavy_dom-2.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR10676. PTHR10676. 1 hit.
PfamiPF12780. AAA_8. 1 hit.
PF08385. DHC_N1. 2 hits.
PF08393. DHC_N2. 1 hit.
PF03028. Dynein_heavy. 1 hit.
PF12777. MT. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 3 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 5 hits.

Sequencei

Sequence statusi: Complete.

E1JJ04-1 [UniParc]FASTAAdd to Basket

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MSQTQFESTS DSADATAESL NNVEPRIVWL KTIMSNMLGV FEPKYVNATI     50
SKNMPAVENF FQRRYETQND LDFVVLFFWR TFYDKLIEEE ITVLEEVPRP 100
PPTVPDKKGK GKKKGDARMA GGKSAGKAGA SAGAAGKGRK KAGQDAAAPA 150
GGDQEAVEEV NTGGETTDAE VEGELEGEEE ATVAGSGKSS ARSRRSKFRK 200
KKATYVPVYV EVKKLVPAYV KTPQVHCHFG RMESCDLDPK IKYIYIVRKN 250
RREIPNFSDV SACFAQMPLY FLLGTVRGSL INSLRDDLNL VYKSAIQFQF 300
REPATADSQQ MDSYEGQAGG SGGGGAGGPA GETGEDISSE AKESGPGLLE 350
LSKPSEFRLR ALKQQKKMKE KEAAAKKAKA KKTDAEPTEE EEEADAHKVE 400
AHLSSSEEEV EIKVEKLTIG QRWEKMLNET KAKVEAEHAA EEATPPRITP 450
IQRRLLKEIE EFQSEITWTI NHIVWAFSLP SSYILPGQEA TEFEDAIIRV 500
PVDPKRLDLV ITYTQQQLEE VVDGWIKYLK KTMKTLTDAK LDDFTPMAEH 550
RYWHKMEVEL YGTLEQLKTE FVVAVLQRLT DDKSPVLDEW QAVVEKTEAR 600
FKLAKENSDY LGTIIDYLEK VRSYESFKMV VLQIPNIMVG LRHIWTMSSH 650
YCRDPEMQVL LCQISNVFVQ KVKSIINFEN IFKYSATYTY ETATNCANLL 700
RCWKQAYKLS RQHIEDSGAG SRWEFDRVAL FNEVNHIHRV AVDIAYVGRV 750
FVQYENLFGH RLKACIADPS IVDNLMRKVY RMLDDLIKSV DYDMFRPGNW 800
ENWEYSLELF NKRLDNVENE AKNVIDQSIN SLLSSEKGLD LVVNAMNIDT 850
RATLQEFVAT KHENLLRFFV TEINAVERVF TKLKKSPPMA KHQPAKISAI 900
FWARLLGKKL KTSVLAFKRV EDEPAIKNSF LKRSSFKQYF ELMTVMFQFE 950
KVLFENFIQN ATYLVNTTNR SNVLRIRICK ESTMSYISEA VQTLKAKPRP 1000
ELQMTSDRRV TPVKSSNLMP VQSEAFSAYS VADSAGTEIS SESENEGLLV 1050
GDTSQKKLMC RINRLTVLVA MIMWMVSNTR KANIQLQECT AFIKMVKDKK 1100
PKDVTAMDRH CVRTCELLQR AESQYLLPIW RELVGEKTLI EYDMDFVVNL 1150
KRDVFDVLFE AQQFEHLGFT LPAVLRTAIM KKDLLFKDYE RMTEVVDRYR 1200
SIINNLSMSE VIFLRGHIYD TELFIQMGVG RYTWTSFNIG KFCDQINSQL 1250
RKLTSIVSQI NFIRLDLRSR IDMIKSFNLF NLDDELKVED TSRSSGESYL 1300
QDRKNPSQRF KSVTGETITM FSVEKDVPAD EKAEQACGSG IYPCQGYFEL 1350
LEASRNRKAA QMKKLYDSLG PVLVKLESLV LGTFSGRSDR MKTYYEYWEG 1400
ETFKCIVDMT YQNLKCYINR LLSNKPMFEV NAVLLMSEIV LEPSVQELQN 1450
TIVTATKDYI SRLRIFTRWM TGTCIACPLV EMGKQFKYNY TYYEDVIQIR 1500
SIVDLVINIH DLASRVANEA RGFVSQFRKY FNLWAFEKSF ICQKFLEKQV 1550
TLIEIDEKFT FYSSIVETLA NTRKFQDIKC VRINLEPLLA SITQHAQDWC 1600
TTLGEELLRH VNDNMRAMRN EVKTLSLNLN KTTRELEDFK LVMTTIGTVQ 1650
SSTLTNEQKI HEMQETFTIL SEHKIMFPYE DMLMAHHLEK RWKRLFLSAL 1700
YRYEKLQPIK QKFADMTSVE IDEFCDDLAE FIKDYDENGP GSVGAELERG 1750
VRLMDPYGQK IAERESRREE LANAERLFDM AMVDYHEFAR VQTEFEGLQQ 1800
LYKLYKAQKY AREGWGKTLW ADLDPNVLTE GVESYLKEFR KFTKAVRTLP 1850
VGVQLEIHMK QFKGTVPLMV SLKHEALRER HWLQLMEKTG QYFDMSPARF 1900
TLENMFAMQL HKYQEIAEQI LTNAIKELQI ERGVQAVIET WASMAFKTFK 1950
HFKGSDDRGW VLGPVDEIMQ ILEDNAMNLQ SMGASQFIGP FLETVNKWER 2000
TLALISEIID EWLVVQRKWL YLEGIFIGGD IRTQLPEEAR KFDDIDKSYR 2050
RIMVDCAKNP LVVPFCTVPG RLVEIQGLGI GLENCQKSLN EYLDSKRRIF 2100
PRFYFISTDE LLSILGSSEP SAVQNHIIKM YDNIKSLRLV KEGSQTIVTG 2150
MISSEGEVME FRHSARAAGR VEYWMNDVLD EMRRSNRFIN KTAIYDFGTD 2200
LQISRPDWLM NYQGMVGLAA SQVWWTAEVE EAFDQAQNHG NMRAMKDFLG 2250
KNNYQIEELV LKVRSNLSRN DRLKFKAQCT VDVHARDIID NFVRDNVLDA 2300
SEFSWESQLR FYWIKFYDNL HVLQCSGSFD FGYEYMGLNG RLVITPLTDR 2350
IYLTITQALL MNLGGAPAGP AGTGKTETVK DLAKAMGLLC VVTNCGEGMD 2400
YRAVGTILSG LVQCGAWGCF DEFNRIDISV LSVISTQLQT IRNGLIRKLD 2450
RFVFEGVEIH LDPKCGVFVT MNPGYAGRTE LPESVKALFR PVTCIKPDLE 2500
LICLISLFSD GFLTAKVLAK KMTVLYSLAQ AQLSKQCHYD WGLRSLNSVL 2550
RMAGVMKRQS EDLPEAVVLM RVLRDMNFPK FVFEDVPLFL GLIKDLFPGI 2600
DCPRIGYPDF NAAVRHVLVN DGYILLPDQE DKVVQMYETM MTRHSTMLVG 2650
PTGGGKTVVI NALVKAQTHM GLPTKCLVLN PKACSVIELY GFLDMETRDW 2700
IDGLFSNIFR EMNKPIEREE RRYACFDGDV DALWIENMNS VMDDNKLLTL 2750
ANGERIRLEN YCALLFEVGN LNYASPATVS RAGMVYVDPK NLRYSPFWQR 2800
WVLTRPEPQR ELLNDFFEKI ITQSIAFILE GLDGTTQGNP LKLVIMQTDL 2850
NMVTQFCNLY DALLPNYVMD SKNYDEPVQQ NYNTDSLECC FLQAVYGSMG 2900
ACLVEKHQPV FDEYMKRISG FPLVQDTPEN PASGGQFPQS KPTLYDYFWD 2950
VKDNVWKAWE WVVQPYTHDP QVKFSEILVP TVDNTRTNRT LSLMSEIKRP 3000
VLLVGEAGTS KTATIMQYLR NLNPSVNVIL NINFSSRTSS LDVQHTLEAA 3050
VEKRTKDTYG PPMGKRIACF IDDMNMPQVD DYGTQQPIAL LKLFFERGGM 3100
YDRDKDLNWK KFKDLTFYAA MGTAGGGRNE VDPRFISMFS TYNIIFPNDE 3150
SLIQIYSSIF KGHMVFVKFQ PEYMLIADMI VHMTLKLFKM VIVDLPPTPS 3200
KFHYIFNLKD LSRIFAGMLL IEPTCFKGLR DLIRVWRNEY TRIICDRLIT 3250
DNDIANVRRN LAVEVAERFP PTFEEEHGFI DAAAAEAEAQ ARLLYEPSKA 3300
DIDGGEEEGE EEEEGEEAPQ VILSLKDYVL RDPLLFGDFR NFTNESEPRL 3350
YEDLLDYNSV YFLFTEILEE YCERKQKMTL VLFEDCLEHL TRVHRTLRMN 3400
RGHVLLIGVG GSGKKCITRL AAFAAECDVF EITISRGYNE AAFREDLKVL 3450
YTIAGVKRKK VVFLFTGAQV AEEGFLELIN NILTVGQVPA LFPDEDKDGI 3500
VNQVRKFAEE DGVSASKDAV WGYFLRTCAE NLHVVLCMSP AGDALRNRCR 3550
NFPGLIGSTY IDWVFPWPRQ ALYAVAKLFL TEHRLIPASH REAIVEHVVH 3600
VHTSIQQYSK DYLAKLRRNN FVTPKHYLDY INTYRGLLEE KAKFITQQRS 3650
RLGEGIKKIE EASVQIDELR IIVTEQKKNV AVASEECEAM LVTIESSTQK 3700
ANVKKAEASE KSVEVEIKGK QIAIEKDEAE EILAEAMPAL EEARLALSQL 3750
EKAQITEIRS FATPPAAVQV VCECVAILKG YKEINWKSAK GMMSDVNFLK 3800
SLMEMDCEAL TQKQITQCRQ HMKTGNLEDM AKISVAGAGL LRFVRAVLGF 3850
FDVYKEVKPK KERLDFLVEE QEVQIKLLNH LNGEIQKLEE KLNELNENYA 3900
TSMKQMRALT EMMQQAERRL IASDKLISGL TSELIRWSKE MASLGQQLID 3950
SVGGCLISAS FLAYTGAFTW EFRKAMVFDD WLEDIASLGI PIQLPFKIDG 4000
YLTTDVEISQ WSNEGLPPDE LSIQNGILTM RASRFPLCID PQLQALQWIR 4050
KREFKNNLKV LSFSDSDFLK QLEMAIMYGT PVLFEDVDDY IDPVIDDILQ 4100
KNIRIQGGRK FVMLGDKEVD WDPSFRVYLT TKFSNPKFDP AVYAKALVIN 4150
YTVTQTGLED QLLSVVVGTE RPDLEAQRES LIAQTSENKQ LLQQLEDSLL 4200
RELSTSTGNM LDNVELIETL ENTKTKAGVV MEQLKLAADT AADIEVLRNG 4250
YRPAAKRGAV LFFALSDMAT VNSMYQYALA AYLDVFVYSL RKAVPDASLN 4300
KRLNNIIKTL TENVYCYGCT GIFERHKLLF SFQIATKLAQ RDGILLQSEL 4350
DFFIKGSIAL TKSERSNPCK WLSEKSWEDV LKLAFDFPDI FGTLPDHFGR 4400
YLTEWKEWFD LENPEEVPCP GDYNIKCNAF QKLMFLRCFR VDRIFRSINQ 4450
YIVETMDEFY IMPPVVSFSA IYEQTSSTIP VCFVLSAGSD PTNDLIKLAD 4500
TIVGMSNFCH ISLGQGQEKA ALRLLDGAIK QGMWLMLQNG HLLIRFVREL 4550
EKHLDRIENP HPDFRLWITT DPTPTFPIGI LQKSLKVVTE PPNGLKLNLR 4600
STYFKVRQER LESCSHVAFR PLVYVLAFFH AVVQERRKYD KLGWNIAYDF 4650
NDTDFDVCTE ILRTYLTRCG TGKIPWNSLK YLIGEVMYGG RVIDDFDRRI 4700
TNCYMNEYMG DFLFDEFKVF HFYEDDNVDY CLPEEETILK EDYIAHIDKL 4750
PLVNKPDVFG LHPNAEIGYY TMAARNIWNS LIELQPQTGE GTGGISRDDF 4800
IDSVAAGILK KLPPAFETWR IRKQIQMSLS PTGVVLLQEL DRFNLLVVRI 4850
KKTLELLRKA IAGEIGMDNV LDNIANSLFN GLLPAAWSKL APATCKQLAS 4900
WLEHLRLRAV QYKYWTLSGE PLVMWLSGLH IPQSYLTALV QIACRRNAWP 4950
LDRSTLFTYV TKFADPDDVE ERPVTGCLVH GLYIEGGRFD LATNQLARSH 5000
PKVLVEELAI LAVEPIEAHR LKLQNTYLAP VYTTSLRRNA MGVGLVFEAN 5050
LATSEDLSHW ILQGVCLTLN TDT 5073
Length:5,073
Mass (Da):580,457
Last modified:November 30, 2010 - v1
Checksum:i2095957C19FECE48
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014297 Genomic DNA. Translation: ACZ95053.1.
RefSeqiNP_001163759.1. NM_001170288.1.
UniGeneiDm.2337.

Genome annotation databases

EnsemblMetazoaiFBtr0301303; FBpp0290518; FBgn0013813.
GeneIDi43379.
KEGGidme:Dmel_CG1842.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014297 Genomic DNA. Translation: ACZ95053.1 .
RefSeqi NP_001163759.1. NM_001170288.1.
UniGenei Dm.2337.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai FBtr0301303 ; FBpp0290518 ; FBgn0013813 .
GeneIDi 43379.
KEGGi dme:Dmel_CG1842.

Organism-specific databases

CTDi 43379.
FlyBasei FBgn0013813. Dhc98D.

Phylogenomic databases

GeneTreei ENSGT00750000117552.
KOi K01509.
OrthoDBi EOG7RRF64.

Miscellaneous databases

GenomeRNAii 43379.
NextBioi 833624.

Gene expression databases

Bgeei E1JJ04.

Family and domain databases

Gene3Di 3.40.50.300. 4 hits.
InterProi IPR003593. AAA+_ATPase.
IPR026983. DHC_fam.
IPR024743. Dynein_HC_stalk.
IPR024317. Dynein_heavy_chain_D4_dom.
IPR004273. Dynein_heavy_dom.
IPR013594. Dynein_heavy_dom-1.
IPR013602. Dynein_heavy_dom-2.
IPR027417. P-loop_NTPase.
[Graphical view ]
PANTHERi PTHR10676. PTHR10676. 1 hit.
Pfami PF12780. AAA_8. 1 hit.
PF08385. DHC_N1. 2 hits.
PF08393. DHC_N2. 1 hit.
PF03028. Dynein_heavy. 1 hit.
PF12777. MT. 1 hit.
[Graphical view ]
SMARTi SM00382. AAA. 3 hits.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 5 hits.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The genome sequence of Drosophila melanogaster."
    Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D.
    , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
    Science 287:2185-2195(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.
  3. Cited for: GENOME REANNOTATION.
    Strain: Berkeley.
  4. "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective."
    Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R., Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., Ashburner M., Celniker S.E.
    Genome Biol. 3:RESEARCH0084-RESEARCH0084(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.
  5. "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly."
    Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A., Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G., Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M., Karpen G.H.
    Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.
  6. "Combined evidence annotation of transposable elements in genome sequences."
    Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D., Ashburner M., Anxolabehere D.
    PLoS Comput. Biol. 1:166-175(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.
  7. "The Release 5.1 annotation of Drosophila melanogaster heterochromatin."
    Smith C.D., Shu S., Mungall C.J., Karpen G.H.
    Science 316:1586-1591(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.
  8. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.

Entry informationi

Entry nameiE1JJ04_DROME
AccessioniPrimary (citable) accession number: E1JJ04
Entry historyi
Integrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: September 3, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

Similar proteinsi