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Protein

Palmitoyltransferase

Gene

CG17196

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.UniRule annotation

GO - Molecular functioni

  • protein-cysteine S-palmitoyltransferase activity Source: FlyBase

GO - Biological processi

  • protein palmitoylation Source: FlyBase

Keywordsi

Molecular functionAcyltransferaseUniRule annotationImported, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
PalmitoyltransferaseUniRule annotation (EC:2.3.1.225UniRule annotation)
Gene namesi
ORF Names:CG17196Imported, Dmel_CG17196Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0039368. CG17196.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei26 – 46HelicalUniRule annotationAdd BLAST21
Transmembranei122 – 143HelicalUniRule annotationAdd BLAST22
Transmembranei168 – 188HelicalUniRule annotationAdd BLAST21

GO - Cellular componenti

  • endoplasmic reticulum Source: FlyBase
  • integral component of membrane Source: UniProtKB-KW

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiFBgn0039368.
ExpressionAtlasiE1JIY0. differential.
GenevisibleiE1JIY0. DM.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini78 – 203DHHCInterPro annotationAdd BLAST126

Domaini

The DHHC domain is required for palmitoyltransferase activity.UniRule annotation

Sequence similaritiesi

Belongs to the DHHC palmitoyltransferase family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

KOiK18932.
OrthoDBiEOG091G0RWR.

Family and domain databases

InterProiView protein in InterPro
IPR001594. Palmitoyltrfase_DHHC.
PfamiView protein in Pfam
PF01529. DHHC. 1 hit.

Sequencei

Sequence statusi: Complete.

E1JIY0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCIVNDWCRE YANLYPKKAV SIGHPLSVIF LLFFVISAIF TTYNILGNLL
60 70 80 90 100
ACYRTSSAVK SLPQERQIPK PGTEHLWHYC DICQKLMPPR SWHCALCKCC
110 120 130 140 150
ILKRDHHCIF AATCIGHNNH RYFFWLTFYL AFGIFMSMAT LFVDVGRSFY
160 170 180 190 200
LLHRMKAGFG NTVKSLSYFR YVCLILNIFA LGFPALMLRF QVQILKLNST
210 220 230 240 250
YYQISSRHHD LGFRNNCQLI MGQRGLWTFI SPSLRSPLPH DGTHWKIKQC

F
Length:251
Mass (Da):29,256
Last modified:November 30, 2010 - v1
Checksum:i2B34774512609CE3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA. Translation: ACZ95029.1.
RefSeqiNP_001163735.1. NM_001170264.2.

Genome annotation databases

EnsemblMetazoaiFBtr0302177; FBpp0291387; FBgn0039368.
GeneIDi43112.
KEGGidme:Dmel_CG17196.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiE1JIY0_DROME
AccessioniPrimary (citable) accession number: E1JIY0
Entry historyiIntegrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: July 5, 2017
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported