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E1JHW5

- E1JHW5_DROME

UniProt

E1JHW5 - E1JHW5_DROME

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Protein
Submitted name:

CG33791, isoform E

Gene

CG33791

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. oxoglutarate dehydrogenase (succinyl-transferring) activity Source: UniProtKB-EC
  2. thiamine pyrophosphate binding Source: InterPro

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
CG33791, isoform EImported (EC:1.2.4.2Imported)
Submitted name:
CG33791, isoform FImported (EC:1.2.4.2Imported)
Gene namesi
ORF Names:CG33791Imported, Dmel_CG33791Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000000803: Chromosome 3L

Organism-specific databases

FlyBaseiFBgn0035240. CG33791.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00530000063092.
KOiK00164.
OrthoDBiEOG7FXZXH.

Family and domain databases

Gene3Di3.40.50.970. 2 hits.
InterProiIPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.

Sequencei

Sequence statusi: Complete.

E1JHW5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNQCRLRSLA RIRRSLTLGL RGTDQHVLAR QALRTIQTTS QRRGVHDLDS
60 70 80 90 100
FANGCSAAYI EGLYNKWKRN PSSVDESWNE LFSSNDWSSP KRSPLQVSHS
110 120 130 140 150
RKYRRPPVER IAVKARSGER TASGGASAAP AAPPSDWKNI DDHHVIQAII
160 170 180 190 200
RAYQSRGHLA ADLDPLGIVG PKKRTSVDGT QRHAAREVLR QHFSYIFNDL
210 220 230 240 250
NTVFKLPSST MIGGDQEFLS LKEILDRLER IYCGHIGVEY MQITSLTKTN
260 270 280 290 300
WLRDRFEKPG GLDLTKEEKK LILERLTRST GFENFLAKKF SSEKRFGLEG
310 320 330 340 350
CDIMIPAIKE VVDRATDHGV ESILIGMAHR GRLNVLANIC RKPISDILSQ
360 370 380 390 400
FHGLQATDSG SGDVKYHLGV FQERLNRQTN RMVRITVVAN PSHLEHVNPV
410 420 430 440 450
LLGKARAEMF QRGDTCGSTV MPIIIHGDAS FSGQGVVYES MHLSDLPNYT
460 470 480 490 500
TYGTIHIVSN NQVGFTTDPR FSRSSRYCTD VAKVVNAPIL HVNADDPEAC
510 520 530 540 550
IQCARIAIDY RTRFKKDVVI DIVGYRRNGH NEADEPMFTQ PLMYQRIKKL
560 570 580 590 600
KPCLQLYADK LIKEGVVTDS EFKAMVSSYE KICEDAWAKS KTIKTIKYSS
610 620 630 640 650
WIDSPWPGFF EGRDRLKLCP TGISTDTLKT IGNMFSTPPP PEHKFETHKG
660 670 680 690 700
ILRILAQRTQ MVQDKVADWS LGEAFAFGSL LKEGIHVRLS GQDVERGTFS
710 720 730 740 750
HRHHVLHHQS EDKVVYNSLD HLYPDQAPYS VSNSSLSECA VLGFEHGYSM
760 770 780 790 800
ASPNALVMWE GQFGDFCNTA QCIIDTFIAS GETKWVRQSG VVMLLPHSME
810 820 830 840 850
GMGPEHSSGR IERFLQMSDD DPDVYPDTCD ADFVARQLMN VNWIVTNLST
860 870 880 890 900
PANLFHCLRR QVKMGFRKPL INFSPKSLLR HPLARSPFKD FNECSCFQRI
910 920 930 940 950
IPDKGPAGKQ PDCVQKLVFC SGKVYYDLVK ERDDHEQVET VALVRVEQLC
960 970 980 990 1000
PFPYDLISQQ LELYPKAELL WAQEEHKNMG AWSYVQPRFD TALLKNENES
1010 1020 1030 1040 1050
RCVSYHGRPP SASPATGNKV QHYNEYKALI TSIFGELTPE NKKRIEDRIK
1060 1070 1080 1090 1100
KQQAKAKADA QSKPSTKPPA APPKGGSSPP PAPTGPAPRK PLISLPSRPP
1110 1120 1130 1140 1150
RGGKQRSGSA PAPNLVDEDS AARNREPDAS AYDGASPSAW KRSGSAPAPS
1160 1170 1180 1190 1200
VVPRASASRS PSRKSPSPSH DGISPSTRQE SLSKKKSGSA PAPTPTSRGP
1210 1220 1230 1240
FRTAPSNTEF IKRRPAKDYG SRNETQSTPG ESELDPTKPQ P
Length:1,241
Mass (Da):138,499
Last modified:November 30, 2010 - v1
Checksum:iA4784543E7B53152
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014296 Genomic DNA. Translation: ACZ94593.1.
AE014296 Genomic DNA. Translation: ACZ94594.1.
RefSeqiNP_001163321.1. NM_001169850.1.
NP_001163322.1. NM_001169851.1.
UniGeneiDm.4028.

Genome annotation databases

EnsemblMetazoaiFBtr0300891; FBpp0290113; FBgn0035240.
FBtr0300892; FBpp0290114; FBgn0035240.
GeneIDi317974.
KEGGidme:Dmel_CG33791.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014296 Genomic DNA. Translation: ACZ94593.1 .
AE014296 Genomic DNA. Translation: ACZ94594.1 .
RefSeqi NP_001163321.1. NM_001169850.1.
NP_001163322.1. NM_001169851.1.
UniGenei Dm.4028.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai FBtr0300891 ; FBpp0290113 ; FBgn0035240 .
FBtr0300892 ; FBpp0290114 ; FBgn0035240 .
GeneIDi 317974.
KEGGi dme:Dmel_CG33791.

Organism-specific databases

FlyBasei FBgn0035240. CG33791.

Phylogenomic databases

GeneTreei ENSGT00530000063092.
KOi K00164.
OrthoDBi EOG7FXZXH.

Miscellaneous databases

GenomeRNAii 317974.
NextBioi 844397.

Family and domain databases

Gene3Di 3.40.50.970. 2 hits.
InterProi IPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view ]
PANTHERi PTHR23152. PTHR23152. 1 hit.
Pfami PF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view ]
PIRSFi PIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTi SM00861. Transket_pyr. 1 hit.
[Graphical view ]
SUPFAMi SSF52518. SSF52518. 2 hits.
TIGRFAMsi TIGR00239. 2oxo_dh_E1. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The genome sequence of Drosophila melanogaster."
    Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D.
    , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
    Science 287:2185-2195(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BerkeleyImported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BerkeleyImported.
  3. Cited for: GENOME REANNOTATION.
    Strain: BerkeleyImported.
  4. "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective."
    Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R., Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., Ashburner M., Celniker S.E.
    Genome Biol. 3:RESEARCH0084.1-RESEARCH0084.20(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BerkeleyImported.
  5. "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly."
    Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A., Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G., Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M., Karpen G.H.
    Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BerkeleyImported.
  6. "Combined evidence annotation of transposable elements in genome sequences."
    Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D., Ashburner M., Anxolabehere D.
    PLoS Comput. Biol. 1:166-175(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BerkeleyImported.
  7. Celniker S., Carlson J., Wan K., Frise E., Hoskins R., Park S., Svirskas R., Rubin G.
    Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  8. "Drosophila melanogaster release 4 sequence."
    Berkeley Drosophila Genome Project
    Celniker S., Carlson J., Wan K., Pfeiffer B., Frise E., George R., Hoskins R., Stapleton M., Pacleb J., Park S., Svirskas R., Smith E., Yu C., Rubin G.
    Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  9. "The Release 5.1 annotation of Drosophila melanogaster heterochromatin."
    Smith C.D., Shu S., Mungall C.J., Karpen G.H.
    Science 316:1586-1591(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BerkeleyImported.
  10. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BerkeleyImported.
  11. FlyBase
    Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiE1JHW5_DROME
AccessioniPrimary (citable) accession number: E1JHW5
Entry historyi
Integrated into UniProtKB/TrEMBL: November 30, 2010
Last sequence update: November 30, 2010
Last modified: October 29, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3