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E1BRU7

- E1BRU7_CHICK

UniProt

E1BRU7 - E1BRU7_CHICK

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Protein
Submitted name:

Uncharacterized protein

Gene

HKDC1

Organism
Gallus gallus (Chicken)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. fructokinase activity Source: RefGenome
  3. glucokinase activity Source: RefGenome
  4. mannokinase activity Source: RefGenome

GO - Biological processi

  1. carbohydrate phosphorylation Source: GOC
  2. cellular glucose homeostasis Source: RefGenome
  3. glucose 6-phosphate metabolic process Source: GOC
  4. glycolytic process Source: RefGenome
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:HKDC1Imported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiTestudines + Archosauria groupArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalliformesPhasianidaePhasianinaeGallus
ProteomesiUP000000539: Chromosome 6

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: RefGenome
Complete GO annotation...

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00390000017159.
InParanoidiE1BRU7.
KOiK00844.
OMAiMCYMEEM.
OrthoDBiEOG7S21X5.
PhylomeDBiE1BRU7.
TreeFamiTF314238.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 2 hits.
PF03727. Hexokinase_2. 2 hits.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E1BRU7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MFAVHLLAFH FAKLKEDQIK KVDRYLYHMR LSDDVLLDVM ARFQAEMVKG
60 70 80 90 100
LGRDTNPTAT VKMLPSFVRS LPDGSEKGDF LAVDLGGSQF RALKVKVFND
110 120 130 140 150
GKQSSQLESE FYPTPKEVIQ GSGAELFSYV ADCLSDFMES RNLKHEKLPL
160 170 180 190 200
GFTFSFPCKQ TKLEEGILLS WTKHFKARGV QGTDVVSSLR NALQKHKDID
210 220 230 240 250
VDVLAMVNDT VGTMMTCGYD DPRCEIGLII GTGTNACYME EMRHINLVEG
260 270 280 290 300
DEGRMCINTE WGAFGDDGAL DDLRTEFDRE LDLGSLNPGK QLFEKMISSL
310 320 330 340 350
YLGELVRLIL LKMTKEGLLF NGKVSAALLT KGKIEMKHVS AMEKYKEGLS
360 370 380 390 400
NTKEILTELN LFPSEDDCIA VQHVCTIVSF RSANLCAAAL AAILTRLREN
410 420 430 440 450
KKLLRLRTTV GIDGGLYKTH PQYPKRLHKV VRRLVPNCDV RFLLSQSGSA
460 470 480 490 500
KGAAMVTAVA HRLAAQRKKI DAVLAPFVLT LETLRDVKNK MRTELEYGLK
510 520 530 540 550
RETQDRATVK MLPTYVCGTP DGTEKGKYLA LDLGGTNFRV LLVKIRSGRR
560 570 580 590 600
RSVRMYNKIF AIPLEIMQGT GEELFDHIVQ CIADFLEYMG IKGARLPLGF
610 620 630 640 650
TFSFPCRQAS IDKGTLVGWT KGFKATDCEG EDVVDMLREA IRRRNEFDLD
660 670 680 690 700
IVAVVNDTVG TMMTCGYEDP NCEIGLIAGT GSNVCYMEDM KNIEIVDGNE
710 720 730 740 750
GKMCINTEWG GFGDNGCIDN IRTKYDKEVD EGSLNAGKQR YEKMTSGMYL
760 770 780 790 800
GEIVRQILID LTKQGLLFRG QISESLRKRG IFETKFLSQI ESDRLALLQV
810 820 830 840 850
RRILQQLGLD STCDDSIIVK EVCGAVSRRA AQLCGAGLAA IVEKKRENRG
860 870 880 890 900
AEHLQITVGV DGTLYKLHPH FSRVLQETVK ELAPRCDVTF MLSEDGSGKG
910
AALITAVAKR LHNIGQK
Length:917
Mass (Da):102,192
Last modified:November 2, 2010 - v1
Checksum:i673D718D28E05F82
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AADN03005060 Genomic DNA. No translation available.
RefSeqiXP_421579.2. XM_421579.4.
UniGeneiGga.11459.

Genome annotation databases

EnsembliENSGALT00000006717; ENSGALP00000006706; ENSGALG00000021039.
GeneIDi423698.
KEGGigga:423698.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AADN03005060 Genomic DNA. No translation available.
RefSeqi XP_421579.2. XM_421579.4.
UniGenei Gga.11459.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSGALT00000006717 ; ENSGALP00000006706 ; ENSGALG00000021039 .
GeneIDi 423698.
KEGGi gga:423698.

Organism-specific databases

CTDi 80201.

Phylogenomic databases

GeneTreei ENSGT00390000017159.
InParanoidi E1BRU7.
KOi K00844.
OMAi MCYMEEM.
OrthoDBi EOG7S21X5.
PhylomeDBi E1BRU7.
TreeFami TF314238.

Miscellaneous databases

NextBioi 20826131.
PROi E1BRU7.

Family and domain databases

InterProi IPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view ]
PANTHERi PTHR19443. PTHR19443. 1 hit.
Pfami PF00349. Hexokinase_1. 2 hits.
PF03727. Hexokinase_2. 2 hits.
[Graphical view ]
PRINTSi PR00475. HEXOKINASE.
PROSITEi PS00378. HEXOKINASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution."
    International Chicken Genome Sequencing Consortium
    Hillier L.W., Miller W., Birney E., Warren W., Hardison R.C., Ponting C.P., Bork P., Burt D.W., Groenen M.A.M., Delany M.E., Dodgson J.B., Chinwalla A.T., Cliften P.F., Clifton S.W., Delehaunty K.D., Fronick C., Fulton R.S., Graves T.A.
    , Kremitzki C., Layman D., Magrini V., McPherson J.D., Miner T.L., Minx P., Nash W.E., Nhan M.N., Nelson J.O., Oddy L.G., Pohl C.S., Randall-Maher J., Smith S.M., Wallis J.W., Yang S.-P., Romanov M.N., Rondelli C.M., Paton B., Smith J., Morrice D., Daniels L., Tempest H.G., Robertson L., Masabanda J.S., Griffin D.K., Vignal A., Fillon V., Jacobbson L., Kerje S., Andersson L., Crooijmans R.P., Aerts J., van der Poel J.J., Ellegren H., Caldwell R.B., Hubbard S.J., Grafham D.V., Kierzek A.M., McLaren S.R., Overton I.M., Arakawa H., Beattie K.J., Bezzubov Y., Boardman P.E., Bonfield J.K., Croning M.D.R., Davies R.M., Francis M.D., Humphray S.J., Scott C.E., Taylor R.G., Tickle C., Brown W.R.A., Rogers J., Buerstedde J.-M., Wilson S.A., Stubbs L., Ovcharenko I., Gordon L., Lucas S., Miller M.M., Inoko H., Shiina T., Kaufman J., Salomonsen J., Skjoedt K., Wong G.K.-S., Wang J., Liu B., Wang J., Yu J., Yang H., Nefedov M., Koriabine M., Dejong P.J., Goodstadt L., Webber C., Dickens N.J., Letunic I., Suyama M., Torrents D., von Mering C., Zdobnov E.M., Makova K., Nekrutenko A., Elnitski L., Eswara P., King D.C., Yang S.-P., Tyekucheva S., Radakrishnan A., Harris R.S., Chiaromonte F., Taylor J., He J., Rijnkels M., Griffiths-Jones S., Ureta-Vidal A., Hoffman M.M., Severin J., Searle S.M.J., Law A.S., Speed D., Waddington D., Cheng Z., Tuzun E., Eichler E., Bao Z., Flicek P., Shteynberg D.D., Brent M.R., Bye J.M., Huckle E.J., Chatterji S., Dewey C., Pachter L., Kouranov A., Mourelatos Z., Hatzigeorgiou A.G., Paterson A.H., Ivarie R., Brandstrom M., Axelsson E., Backstrom N., Berlin S., Webster M.T., Pourquie O., Reymond A., Ucla C., Antonarakis S.E., Long M., Emerson J.J., Betran E., Dupanloup I., Kaessmann H., Hinrichs A.S., Bejerano G., Furey T.S., Harte R.A., Raney B., Siepel A., Kent W.J., Haussler D., Eyras E., Castelo R., Abril J.F., Castellano S., Camara F., Parra G., Guigo R., Bourque G., Tesler G., Pevzner P.A., Smit A., Fulton L.A., Mardis E.R., Wilson R.K.
    Nature 432:695-716(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Red jungle fowlImported.
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Red jungle fowlImported.

Entry informationi

Entry nameiE1BRU7_CHICK
AccessioniPrimary (citable) accession number: E1BRU7
Entry historyi
Integrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 2, 2010
Last modified: October 29, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3