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Protein
Submitted name:

Hexokinase domain containing 1

Gene

HKDC1

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseSAAS annotation, Transferase
Biological processGlycolysisSAAS annotation
LigandATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Hexokinase domain containing 1Imported
Gene namesi
Name:HKDC1Imported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiE1BRU7.
PRIDEiE1BRU7.

Expressioni

Gene expression databases

BgeeiENSGALG00000021039.

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000006706.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini22 – 219Hexokinase_1InterPro annotationAdd BLAST198
Domaini225 – 459Hexokinase_2InterPro annotationAdd BLAST235
Domaini470 – 667Hexokinase_1InterPro annotationAdd BLAST198
Domaini673 – 907Hexokinase_2InterPro annotationAdd BLAST235

Sequence similaritiesi

Belongs to the hexokinase family.SAAS annotation

Phylogenomic databases

eggNOGiKOG1369. Eukaryota.
COG5026. LUCA.
GeneTreeiENSGT00390000017159.
InParanoidiE1BRU7.
OMAiKIETRHV.
OrthoDBiEOG091G08MD.
PhylomeDBiE1BRU7.
TreeFamiTF314238.

Family and domain databases

InterProiView protein in InterPro
IPR001312. Hexokinase.
IPR019807. Hexokinase_BS.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiView protein in Pfam
PF00349. Hexokinase_1. 2 hits.
PF03727. Hexokinase_2. 2 hits.
PROSITEiView protein in PROSITE
PS00378. HEXOKINASE_1. 1 hit.
PS51748. HEXOKINASE_2. 2 hits.

Sequencei

Sequence statusi: Complete.

E1BRU7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFAVHLLAFH FAKLKEDQIK KVDRYLYHMR LSDDVLLDVM ARFQAEMVKG
60 70 80 90 100
LGRDTNPTAT VKMLPSFVRS LPDGSEKGDF LAVDLGGSQF RALKVKVFND
110 120 130 140 150
GKQSSQLESE FYPTPKEVIQ GSGAELFSYV ADCLSDFMES RNLKHEKLPL
160 170 180 190 200
GFTFSFPCKQ TKLEEGILLS WTKHFKARGV QGTDVVSSLR NALQKHKDID
210 220 230 240 250
VDVLAMVNDT VGTMMTCGYD DPRCEIGLII GTGTNACYME EMRHINLVEG
260 270 280 290 300
DEGRMCINTE WGAFGDDGAL DDLRTEFDRE LDLGSLNPGK QLFEKMISSL
310 320 330 340 350
YLGELVRLIL LKMTKEGLLF NGKVSAALLT KGKIEMKHVS AMEKYKEGLS
360 370 380 390 400
NTKEILTELN LFPSEDDCIA VQHVCTIVSF RSANLCAAAL AAILTRLREN
410 420 430 440 450
KKLLRLRTTV GIDGGLYKTH PQYPKRLHKV VRRLVPNCDV RFLLSQSGSA
460 470 480 490 500
KGAAMVTAVA HRLAAQRKKI DAVLAPFVLT LETLRDVKNK MRTELEYGLK
510 520 530 540 550
RETQDRATVK MLPTYVCGTP DGTEKGKYLA LDLGGTNFRV LLVKIRSGRR
560 570 580 590 600
RSVRMYNKIF AIPLEIMQGT GEELFDHIVQ CIADFLEYMG IKGARLPLGF
610 620 630 640 650
TFSFPCRQAS IDKGTLVGWT KGFKATDCEG EDVVDMLREA IRRRNEFDLD
660 670 680 690 700
IVAVVNDTVG TMMTCGYEDP NCEIGLIAGT GSNVCYMEDM KNIEIVDGNE
710 720 730 740 750
GKMCINTEWG GFGDNGCIDN IRTKYDKEVD EGSLNAGKQR YEKMTSGMYL
760 770 780 790 800
GEIVRQILID LTKQGLLFRG QISESLRKRG IFETKFLSQI ESDRLALLQV
810 820 830 840 850
RRILQQLGLD STCDDSIIVK EVCGAVSRRA AQLCGAGLAA IVEKKRENRG
860 870 880 890 900
AEHLQITVGV DGTLYKLHPH FSRVLQETVK ELAPRCDVTF MLSEDGSGKG
910
AALITAVAKR LHNIGQK
Length:917
Mass (Da):102,192
Last modified:November 2, 2010 - v1
Checksum:i673D718D28E05F82
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AADN04000213 Genomic DNA. No translation available.
RefSeqiXP_421579.2. XM_421579.5.
UniGeneiGga.11459.

Genome annotation databases

EnsembliENSGALT00000006717; ENSGALP00000006706; ENSGALG00000021039.
GeneIDi423698.

Similar proteinsi

Entry informationi

Entry nameiE1BRU7_CHICK
AccessioniPrimary (citable) accession number: E1BRU7
Entry historyiIntegrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 2, 2010
Last modified: September 27, 2017
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported