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Protein
Submitted name:

Uncharacterized protein

Gene

CENPE

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi86 – 93ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMotor proteinPROSITE-ProRule annotation
LigandATP-bindingPROSITE-ProRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-GGA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
R-GGA-2467813 Separation of Sister Chromatids
R-GGA-2500257 Resolution of Sister Chromatid Cohesion
R-GGA-5663220 RHO GTPases Activate Formins
R-GGA-6811434 COPI-dependent Golgi-to-ER retrograde traffic
R-GGA-68877 Mitotic Prometaphase
R-GGA-983189 Kinesins

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:CENPEImported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiE1BQJ6

Expressioni

Gene expression databases

BgeeiENSGALG00000013208

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000021544

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 330Kinesin motorInterPro annotationAdd BLAST325

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili346 – 366Sequence analysisAdd BLAST21
Coiled coili521 – 555Sequence analysisAdd BLAST35
Coiled coili577 – 625Sequence analysisAdd BLAST49
Coiled coili667 – 701Sequence analysisAdd BLAST35
Coiled coili706 – 726Sequence analysisAdd BLAST21
Coiled coili745 – 779Sequence analysisAdd BLAST35
Coiled coili807 – 876Sequence analysisAdd BLAST70
Coiled coili895 – 997Sequence analysisAdd BLAST103
Coiled coili1009 – 1043Sequence analysisAdd BLAST35
Coiled coili1048 – 1075Sequence analysisAdd BLAST28
Coiled coili1085 – 1119Sequence analysisAdd BLAST35
Coiled coili1127 – 1161Sequence analysisAdd BLAST35
Coiled coili1189 – 1282Sequence analysisAdd BLAST94
Coiled coili1315 – 1504Sequence analysisAdd BLAST190
Coiled coili1509 – 1536Sequence analysisAdd BLAST28
Coiled coili1541 – 1582Sequence analysisAdd BLAST42
Coiled coili1680 – 1700Sequence analysisAdd BLAST21
Coiled coili1777 – 1797Sequence analysisAdd BLAST21
Coiled coili1865 – 1885Sequence analysisAdd BLAST21
Coiled coili1900 – 1948Sequence analysisAdd BLAST49
Coiled coili1990 – 2010Sequence analysisAdd BLAST21
Coiled coili2022 – 2049Sequence analysisAdd BLAST28
Coiled coili2105 – 2132Sequence analysisAdd BLAST28

Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.PROSITE-ProRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0242 Eukaryota
COG5059 LUCA
GeneTreeiENSGT00910000143992
InParanoidiE1BQJ6
KOiK11498
OMAiSVCRASW
OrthoDBiEOG091G0CFT
TreeFamiTF330343

Family and domain databases

Gene3Di3.40.850.10, 1 hit
InterProiView protein in InterPro
IPR027640 Kinesin-like_fam
IPR019821 Kinesin_motor_CS
IPR001752 Kinesin_motor_dom
IPR036961 Kinesin_motor_dom_sf
IPR027417 P-loop_NTPase
PANTHERiPTHR24115 PTHR24115, 6 hits
PfamiView protein in Pfam
PF00225 Kinesin, 1 hit
PRINTSiPR00380 KINESINHEAVY
SMARTiView protein in SMART
SM00129 KISc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00411 KINESIN_MOTOR_1, 1 hit
PS50067 KINESIN_MOTOR_2, 1 hit

Sequencei

Sequence statusi: Complete.

E1BQJ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEEGAVTVC VRVRPLIARE SALEDKASLY WKSEGNTVSE VNGTKVFNYD
60 70 80 90 100
RVFHSCDNTQ QVYEDVAVPI IQSAVQGYNG TIFAYGQTAS GKTYTMMGNK
110 120 130 140 150
DSLGIIPKAI QHVFKIICEI PDREFLLRVS YMEIYNETIT DLLCNIRKKK
160 170 180 190 200
PLGIREDVNR NTYVEDLIEE VVVSPEQVME WIRKGEKNRH YGETKMNEHS
210 220 230 240 250
SRSHTIFRMI IESRERSDPA NANCDGAVMV SHLNLVDLAG SERASQTGSE
260 270 280 290 300
GVRLKEGCNI NRSLFILGQV IKKLCDDPSS FINYRDCKLT RILQNSLGGN
310 320 330 340 350
AKTVIICTIT PVSFDETLST LQFANTAKRM KNTPKVNEVL DDDALLKRYR
360 370 380 390 400
KEILDLKKQL EEVSMKTQIH AMEKHQLAHL LEEKNSLQKM QEDRIRNLTE
410 420 430 440 450
MLVTSASFSS KQNAKARRRR RVTWAPGKIN QENVDYFEDF EKTLTTTKKM
460 470 480 490 500
KMSLSSLPEA EDSMLIESSE RDNQYFTVPD QIQDTEWIDG PNMNWTQKDF
510 520 530 540 550
EESVQLCEAL AVEKDIAVNE INILQDNFNK LVLENEQLKS EINEMKEKLK
560 570 580 590 600
EKIEMDEFEA LEKQTQRDHE IQLMHEITNL KNIISNAEAY NEELEIEIKS
610 620 630 640 650
KLEQLKEKED KIKILQNRVE ELQKVDVEKK DMSLSVGDSD KLIEEIQQLS
660 670 680 690 700
KSLLDSETVA LDAKKESAFL RTENLELKEQ MNELLNNHKQ MQKDVQLYQS
710 720 730 740 750
QIEAGKANYK KMQADLQKEL QSVFQENTRL NLLMEGKVPK DLVSLLDLEK
760 770 780 790 800
KASDLKAELE KALEENVLLQ KKVNELSELQ SLPNTVEMQQ REILEKHEEL
810 820 830 840 850
SLLKLEREKL LSEAADNEVK LNSVTEEIEK SKKELADAQL KYINSNQEYV
860 870 880 890 900
ALKQLHEELE QKYLAVSENS EQMKLQIEHL SKDAEESKTA LDYVKLELSN
910 920 930 940 950
KMKELEEKTA EHEHHLHVKE ELAQAHRKLD EMEQLKEQEK IMEARLETKD
960 970 980 990 1000
SEIQAVLQQL SGCQEEIKTL TQERDHLKQK EESLQAETDQ LKEDIKDTVS
1010 1020 1030 1040 1050
MNILAHEELR NAQSSLQKSQ ETVKKLEKII SEKETQILSV EETLGKTTDE
1060 1070 1080 1090 1100
LKIQLSQMTE ELKNITSERD CLAAENKSHR ESGELQVLKE QIFSLTQERN
1110 1120 1130 1140 1150
SLQDKLDSLH LKKEEYGEET LESVIQEKSV EQELLHLREE LSQAKKKLHE
1160 1170 1180 1190 1200
MEEMKASEFN RESEKVEQTD LIPKLHDCRE MSTMTERDDD DFKMQLENLQ
1210 1220 1230 1240 1250
NERDHLRNTV EEAISMNSEV QKELRCAQNS IRQHQETIVE LKESISEKES
1260 1270 1280 1290 1300
QLLKAQEALK ETAELEQKLT EVTENLTHIS SEYGKLLAEK EQIERAMNED
1310 1320 1330 1340 1350
VSQQLEKIAL LSVEKDELQQ MVEVSKTEND QLKADCQESK DKLIEVLTEM
1360 1370 1380 1390 1400
ENLQEELKHQ KEQADLQKNM LVEGEEKLQN TEEKLTEEIN KLKEKIDKLN
1410 1420 1430 1440 1450
EDLNLVTEER QQVLEELKEK TEHENSKLQE LGKQCALLAQ ERDQVQETLE
1460 1470 1480 1490 1500
CVQAEKKKLE VNLQESINKI LETEKELKCH QELLSNEKMK AEEQEEHLLK
1510 1520 1530 1540 1550
VQRRSEILQD SLTNKIQQLT ETLNSISSEK DLLLAERATH SSQLKEQISS
1560 1570 1580 1590 1600
ISQEKDELQK LLQDISSERD QLKMELQKSS EMCIETSTKL ECALNKLKQR
1610 1620 1630 1640 1650
DLNDMSVQVN LLDNTEQIDD DSLVAKSLKI KELLEIFPDI RKRYDCLSTT
1660 1670 1680 1690 1700
SLNLKAELDS QKAVVAAILT QLSSDQSKEV NRLQMENERI NGHLQSLLNK
1710 1720 1730 1740 1750
LKFLFGRVCS KRKDYHATVN KYVMELYEEK KKQHQLQVQI QCLKRFHSDS
1760 1770 1780 1790 1800
NETSSQELNA EVWQSLHLNT QIILKDVSEM ESELLSIEAE LQQEASTRKE
1810 1820 1830 1840 1850
TTQFWETCSG HHCDTEELKE ELKKDNERLL QVIKFWTPKG KILLQLSSEL
1860 1870 1880 1890 1900
DDRTLTYCKN ADIEWKQRKE KSEELLQDLE TLKEQLAPGR SAHLLIEEEN
1910 1920 1930 1940 1950
SKLHTELKAA KQDIKALEAK LQKLENSVNE AGKNLREKDD KINKLQAQIR
1960 1970 1980 1990 2000
ITTASSELTQ LQAKLNETEK CLRASLTENQ SLQAKLDKGA KLYKEEIDQL
2010 2020 2030 2040 2050
KTQLVKCDME RMKQSNSFDM KLANYKALAE HQEEQLRKLK EELRRAQQEQ
2060 2070 2080 2090 2100
DVTVMSEKAA PQLSQMPMPI TCGGGSGIVQ STQILVLKSE QVKLQKENLH
2110 2120 2130 2140 2150
LKKQNDVLLS NELQLKEELR KWKERALKLR ERFSRESTQE TVPRSPRKTV
2160 2170 2180 2190 2200
SCSVKEPTSP SKESLSQETV TQYISKPLPL TCPTNFFDNS NLSTLTDTQP
2210 2220
AGTESTEDHF KKWFETSEKD RVSDCNTQ
Length:2,228
Mass (Da):257,850
Last modified:June 26, 2013 - v2
Checksum:i82AF99087A7823AC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AADN04000077 Genomic DNA No translation available.
RefSeqiXP_015141087.1, XM_015285601.1

Genome annotation databases

EnsembliENSGALT00000021577; ENSGALP00000021544; ENSGALG00000013208
GeneIDi422716
KEGGigga:422716

Similar proteinsi

Entry informationi

Entry nameiE1BQJ6_CHICK
AccessioniPrimary (citable) accession number: E1BQJ6
Entry historyiIntegrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: June 26, 2013
Last modified: April 25, 2018
This is version 69 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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