E1BN63 (E1BN63_BOVIN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Uncharacterized protein Ensembl ENSBTAP00000006875

Gene names

Name:

WNK1 Ensembl ENSBTAP00000006875

Organism

Bos taurus (Bovine) [Reference proteome] Ensembl ENSBTAP00000006875

Taxonomic identifier

9913 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Laurasiatheria › Cetartiodactyla › Ruminantia › Pecora › Bovidae › Bovinae › Bos

Protein attributes

Sequence length	2377 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSBTAP00000006875

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	intracellular protein kinase cascade Inferred from electronic annotation. Source: Compara ion transport Inferred from electronic annotation. Source: Compara negative regulation of pancreatic juice secretion Inferred from electronic annotation. Source: Compara negative regulation of phosphatase activity Inferred from electronic annotation. Source: Compara positive regulation of systemic arterial blood pressure Inferred from electronic annotation. Source: Compara
Cellular_component	cytoplasm Inferred from electronic annotation. Source: Compara
Molecular_function	ATP binding Inferred from electronic annotation. Source: Compara protein serine/threonine kinase activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E1BN63 [UniParc]. Last modified November 16, 2011. Version 2. Checksum: 3C468A520ECFF3B1	FASTA	2,377	247,464
	10 20 30 40 50 60 MSGGAADQQS SAQGSLFLSP PAPAPKNGSS SDSSVGEKLG AAAADAAAGR TEEYRRRRHT 70 80 90 100 110 120 MDKDSRGAAA TTTTEHRFFR RSVICDSNAT ALELPGLPLP LPQPGAAAVV PQRSPPEPPR 130 140 150 160 170 180 EETLIPAAAA QVAQQPPAAA AAAAAAAPEE PVAASPATSS APSSAGRDRQ AVQPGPAGSR 190 200 210 220 230 240 EEPPTSRSGS GGGSAKEPQE ERSQQQDDIE ELETKAVGMS NDGRFLKFDI EIGRGSFKTV 250 260 270 280 290 300 YKGLDTETTV EVAWCELQDR KLTKSERQRF KEEAEMLKGL QHPNIVRFYD SWESTVKGKK 310 320 330 340 350 360 CIVLVTELMT SGTLKTYLKR FKVMKIKVLR SWCRQILKGL QFLHTRTPPI IHRDLKCDNI 370 380 390 400 410 420 FITGPTGSVK IGDLGLATLK RASFAKSVIG TPEFMAPEMY EEKYDESVDV YAFGMCMLEM 430 440 450 460 470 480 ATSEYPYSEC QNAAQIYRRV TSGVKPASFD KVAIPEVKEI IEGCIRQNKD ERYSIKDLLN 490 500 510 520 530 540 HAFFQEETGV RVELAEEDDG EKIAIKLWLR IEDIKKLKGK YKDNEAIEFS FDLEKDVPED 550 560 570 580 590 600 VAQEMVDSGY VCEGDHKTMA KAIKDRVSLI KRKREQRQLV REEQEKRKQE ESSFKQQVEQ 610 620 630 640 650 660 QPSTAQAGVQ QPPATSTGGP AASAASASVS TQVEPEEPEA DQHQQLQYQQ PGVSVISDGT 670 680 690 700 710 720 VDSGQGSSVF TESRVSSQQT VSYGSQHEQA PSTGALPGHT ASVVQTQAQP HAVYPPSSLA 730 740 750 760 770 780 QGQSQGQPSS SSLTGVPSSQ PMQHSQQQQG VQPTAPSQQA VQYPLPQTSA PSEATIAQPV 790 800 810 820 830 840 SQPPPPQALP HVSAGKQLPV SQPVPTLQGE PQIPVATQPS VVPVHAGAHF LPVGQPLPPS 850 860 870 880 890 900 LLPQYPVSQL PPISQLPSAP PHVSVAQPGF PPLPVTMAAG VSQPLLTLAS SAAAAAVPGA 910 920 930 940 950 960 PTVVPSQLPA LLQPVTQLPS QAHPQLLQPA VQSMGIPASL GQTAEVPLPP GDILYQGFPP 970 980 990 1000 1010 1020 RLPSQYPGDS NIAPSSSAAS VCLPSAVLSP PMPTEALAAP GYFPAMVQPY VESSLLVPVG 1030 1040 1050 1060 1070 1080 SVGGQVQVSQ PAVSLAQAPT TSSQQAALES TQVVSQVAPP EPAPGAQPQP AQPAAVVSSI 1090 1100 1110 1120 1130 1140 DSAHSDVASG LSDGNENVPS SSGRHEGRTT KRLHRKSIRS RSRHEKPSRP KLRILNVSNK 1150 1160 1170 1180 1190 1200 GDRVVECQLE THNRKMVTFK FDLDGDNPEE IATIMVNNDF ILALERDAFV EQVREIIEKA 1210 1220 1230 1240 1250 1260 DEMLSEDVSV EPEGDQSLES LHGKDDYGFS GTQKLEGEFK QPIPASSLPQ QIAGIPASSL 1270 1280 1290 1300 1310 1320 TQVVHSAGRR FIVSPVPESR LRESKLFTEI SDTVAASTSA GPGMNLSHSA SSLSLQQAFS 1330 1340 1350 1360 1370 1380 ELRHARMAEG PSTAPPHFGQ TGPVFPAVPP TLSSAPGAPA AAAAASVSAP APSHPLSDVT 1390 1400 1410 1420 1430 1440 TSVIQTEVTV APGTGVMPPS GLPVPPVSES LAPSSVAPSV TIPAVLSALP APQAAQAPTP 1450 1460 1470 1480 1490 1500 GSGASSAGTF PSAPASLTPA SAVGSAVASA AQLPPVPSQP AVGSSTGVAT LTAVPAAALG 1510 1520 1530 1540 1550 1560 PSLTALPSLA LSSSTSAPAL AETVLVSAHA LDKTAHSSTT GLALSLPATS SSPAPGAGVS 1570 1580 1590 1600 1610 1620 SAVSQPTAAA HPLVLPSVVT STPVLSQAGP MSAPLLPQVP GIPPLVQPVV SVPAVQQTLV 1630 1640 1650 1660 1670 1680 HSQPQPAPLP NQPHTHCPEI DADTQPKAPG IDDIKTLEEK LRSLFSEHSS SGAQHAPVSL 1690 1700 1710 1720 1730 1740 ETSLTVETAV TAGLPTTAVA PSKPLTSTAS TCLPPTSLPL GAAGLSVIPM VTPGQVSTPV 1750 1760 1770 1780 1790 1800 SSAPGVKLET APAKPPLTKP PVLPMGTELP AGTPPSEQLP PFPGPSLTQP PQPLGDLDAQ 1810 1820 1830 1840 1850 1860 LRRTLSPESG MLTSAVGPVS VVAPTAVVET EAQLPKDVSQ VTEAPVLAPT STAGVLKMGR 1870 1880 1890 1900 1910 1920 FQVSVAMDDP QKEGKSKSED AKSVHFASST SESSVLSSSS PESTVVKAEP NGLAVRGASA 1930 1940 1950 1960 1970 1980 DMPDSAHQPP ASEAGQPSKV GRFQVTTTAS RVGRFSVSRT EDKMAEVKGE EPVVSPFMDS 1990 2000 2010 2020 2030 2040 EHDIPPTVTP KKEKPELSEP SHLNGPSSDL EAAFLSRDVD AGSGSPHSPP QLSSKSLPAQ 2050 2060 2070 2080 2090 2100 SLSQSLSNSF NSSYMSSDNE SDIEDEDLKL ELRRLREKHL KEIQDLQSRQ KHEIESLYTK 2110 2120 2130 2140 2150 2160 LGKVPPAVII PPAAPLAGRR RRPTKSKGSK SSRSSSLGNK SPGPGTLSGQ SAASVLHPQQ 2170 2180 2190 2200 2210 2220 TLPAPGSVPE TGPNQLLQPV KPSPSSDNLY SAFTSDGAIS VPSLSAPGQG TSSTNAVGGA 2230 2240 2250 2260 2270 2280 VSSQAAPAPP PAVTSSRKGM FTDDLHKLVD NWARDAMSLS GRRGSKGHVS YEGPGMARKF 2290 2300 2310 2320 2330 2340 SAPGQLCVSM TSNLGGSAPG SAASATSLGH FPKSMCPPQQ YGFPTPPFGT QWSGTGGPAP 2350 2360 2370 QPLSQFQPVG TASLQNFNIS NLQKSISNPP GSNLRTT

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A whole-genome assembly of the domestic cow, Bos taurus." Zimin A.V., Delcher A.L., Florea L., Kelley D.R., Schatz M.C., Puiu D., Hanrahan F., Pertea G., Van Tassell C.P., Sonstegard T.S., Marcais G., Roberts M., Subramanian P., Yorke J.A., Salzberg S.L. Genome Biol. 10:R42-R42(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Hereford Ensembl ENSBTAP00000006875.
[2]	Ensembl Submitted (MAY-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: Hereford Ensembl ENSBTAP00000006875.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DAAA02014590 Genomic DNA. No translation available. DAAA02014591 Genomic DNA. No translation available. DAAA02014592 Genomic DNA. No translation available.
IPI	IPI01004282.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSBTAT00000006875; ENSBTAP00000006875; ENSBTAG00000005221.
Phylogenomic databases
GeneTree	ENSGT00550000074385.
OMA	APFGTQW.
Family and domain databases
InterPro	IPR011009. Kinase-like_dom. IPR024678. Kinase_OSR1/WNK_CCT. IPR000719. Prot_kinase_cat_dom. IPR008271. Ser/Thr_kinase_AS. [Graphical view]
Pfam	PF12202. OSR1_C. 1 hit. PF00069. Pkinase. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

E1BN63_BOVIN

Accession

Primary (citable) accession number: E1BN63

Entry history

Integrated into UniProtKB/TrEMBL:	November 2, 2010
Last sequence update:	November 16, 2011
Last modified:	March 6, 2013
This is version 18 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)