E1BKN0 (E1BKN0_BOVIN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Uncharacterized protein Ensembl ENSBTAP00000003584

Gene names

Name:

LOC785776 Ensembl ENSBTAP00000003584

Organism

Bos taurus (Bovine) [Reference proteome] Ensembl ENSBTAP00000003584

Taxonomic identifier

9913 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Laurasiatheria › Cetartiodactyla › Ruminantia › Pecora › Bovidae › Bovinae › Bos

Protein attributes

Sequence length	2711 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity	S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone]. SAAS SAAS001214
Sequence similarities	Contains 1 SET domain. RuleBase RU004538 Contains 1 post-SET domain. RuleBase RU004541 SAAS SAAS001214
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSBTAP00000003584

Ontologies

Keywords
Cellular component	Nucleus SAAS SAAS003616
Domain	Zinc-finger SAAS SAAS001965
Ligand	Metal-binding Zinc
Molecular function	Methyltransferase SAAS SAAS001214 RuleBase RU004541 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	gene silencing Inferred from electronic annotation. Source: Compara histone H3-K4 trimethylation Inferred from electronic annotation. Source: Compara oocyte differentiation Inferred from electronic annotation. Source: Compara ovarian follicle development Inferred from electronic annotation. Source: Compara ovulation Inferred from electronic annotation. Source: Compara regulation of histone H3-K4 methylation Inferred from electronic annotation. Source: Compara
Cellular_component	histone methyltransferase complex Inferred from electronic annotation. Source: Compara
Molecular_function	DNA binding Inferred from electronic annotation. Source: InterPro histone methyltransferase activity (H3-K4 specific) Inferred from electronic annotation. Source: Compara zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E1BKN0 [UniParc]. Last modified November 16, 2011. Version 2. Checksum: BED4A79F7DA60E24	FASTA	2,711	293,366
	10 20 30 40 50 60 MAAAAGGGSC PGPGSARGRF PGRPRGSGGG GGRGGRGNGA ERVRVALRRG GGAAGPGGAE 70 80 90 100 110 120 PGEDTALLRL LGLHRGLRRL RRLWAGPRIQ RGRGRGRGRG WGPSRGCLLE EESSDGESDD 130 140 150 160 170 180 EEFQGFHSDE DAASSSLRSA LRSQRGRAPR GRGRKHKTTP LPPPRLADVA PAPPKTPARK 190 200 210 220 230 240 RGEEGTERMV QALTELLRRA QAPPAPRSRA CESSTPRRSR GRPPGRPAGP CRKKQQAVVV 250 260 270 280 290 300 AEAAVTIPRP EPPPPVVPVK HRTGSWKCKE GPGPGPGTPK RGGQSGRGGR GGRGRGRGRL 310 320 330 340 350 360 PLVIKFVSKA KKMKMGQLSL GLESGQGQDQ HEESWQDAPQ GRVGSGQGEG PCWRKEQKLE 370 380 390 400 410 420 EEGEEEKEEE DEEEERAVAE EAMVLAEEKE EAKLPSPPLT PPAPPPPPSL PPASASPPSP 430 440 450 460 470 480 LCPPPPPVSP PPPPTPPPPR APEEQEESPP PVVPATCSRK RGRPPLTPSQ RAEREAARAG 490 500 510 520 530 540 PEGTSPPTPV PSTATGGPLE DSPTVAPKST TFLKNIRQFI MPVVSARSSR VIKTPRRFMD 550 560 570 580 590 600 EDPPKPPKVE VSPTLRPPIA TSPLAPQEPA PAPSPPRAPT PPSTPVPLPE KRRSILREPT 610 620 630 640 650 660 FRWTSLTREL PPPPPAPPPA PPPLPAPVTP SRRPLLLRAP QFTPSEAHLK IYESVLTTPP 670 680 690 700 710 720 LGAPEAPEPE PPPADDSPAE PEPRALGRTN HLSLPRFAPV VATPIKAEMP SPGAPAPSSG 730 740 750 760 770 780 QQPHAQLQQP LQALQTQLLP PALPPQQSLL QPQLQLQPPP QQAPPLEKAR IAGLGSLPLS 790 800 810 820 830 840 GVEEKMFSLL KRAKVQLIKI DQQQQQKVAS LMPPSPGGQM EEVVGTVKQI PDRGSVKSED 850 860 870 880 890 900 ESVETKRERP SGPESPVQGP RIKHVCRHAA VALGQARAMV PEDVPRLSAL PLRDRQDLNA 910 920 930 940 950 960 EDTSSASETE SVPSQSQPGK VESTGPGGDS EPAGSGGTLA HAPRRSLPSH HGKKMRMARC 970 980 990 1000 1010 1020 GHCRGCLRVQ DCGSCVNCLD KPKFGGPNTK KQCCVYRKCD KIEARKMERL AKKGRTIVKT 1030 1040 1050 1060 1070 1080 LLPWDSDESP EASPGPPGPR RGAGAGGPRE EVVAPPGPEE QDSFLLQRKS ARRCVKQRPS 1090 1100 1110 1120 1130 1140 YDIFEDSDDS DPGGPPAPRR RTPRENELPV PEPEEQSRPR KPTLQPVLQL KARRRLDKDA 1150 1160 1170 1180 1190 1200 LAPGPFASFP NGWTGKQKSP DGVHRVRVDF KEDCDLENVW LMGGLSVLTS VPGGPPMVCL 1210 1220 1230 1240 1250 1260 LCASKGLHEL VFCQVCCDPF HPFCLEEAER PLPQHHDTWC CRRCKFCHVC GRKGRGSKHL 1270 1280 1290 1300 1310 1320 LECERCRHAY HPACLGPSYP TRATRKRRHW ICSACVRCKS CGATPGKNWD VEWSGDYSLC 1330 1340 1350 1360 1370 1380 PRCTQLFEKG NYCPICTRCY EDNDYESKMM QCAQCDHWVH AKCEGLSDED YEILSGLPDS 1390 1400 1410 1420 1430 1440 VLYTCGPCAG ATHPRWREAL SGALQGGLRQ VLQGLLSSKV AGPLLLCTQC GQEGQQLHPG 1450 1460 1470 1480 1490 1500 PCDLHAVRRR FEEGHYKSVH SFMEDVVGIL MRHSEEGEML ERRAGGQTKG LLLKLLESAF 1510 1520 1530 1540 1550 1560 GWFDAHDPKY WRRSTRLPNG VLPNAVLPPS LDHVYAQWRQ QEPETPESGQ PPGDPSTAFQ 1570 1580 1590 1600 1610 1620 GKDSAAFSHL EDPRQCALCL KYGDADSKEA GRLLYIGQNE WTHVNCAIWS AEVFEENDGS 1630 1640 1650 1660 1670 1680 LKNVHAAVAR GRQMRCELCL KPGATVGCCL SSCLSNFHFM CARASYCIFQ DDKKVFCQKH 1690 1700 1710 1720 1730 1740 TDLLDGKEIV NPDGFDVLRR VYVDFEGINF KRKFLTGLEP DAINVLIGSI RIDSLGTLSD 1750 1760 1770 1780 1790 1800 LSDCEGRLFP IGYQCSRLYW STVDARRRCW YRCRILEYRP WGPREEPVHL EAAEENQTIV 1810 1820 1830 1840 1850 1860 HSPAPCSEPP DHVDPPPDTD ALIPRAPEHH PPVQNPDPPP RLDPSSAPPP APRSFSGARI 1870 1880 1890 1900 1910 1920 KVPNYSPSRR PLGGVSFGPL PSPGSPSSLT HHIPTVGDPD FPAPPRRSRR PSPLASRLPP 1930 1940 1950 1960 1970 1980 SRRASPPLRT SPQLRVPPPT SVVRALTPTS GELAPPSRAP SPPPPPEDLG PDFEDMEVVS 1990 2000 2010 2020 2030 2040 GLSAADLDFA ASLLGTEPFQ EEIVAAGAGG SSHGGLGDSS EEEAGPTPRY VHFPVTVVSG 2050 2060 2070 2080 2090 2100 PALAPGALPG APRIEQLDGV DDGTDSEAEA VQQPRGQGTP TSGPGAGRAG VIGAAGDRAR 2110 2120 2130 2140 2150 2160 PPEDLPSEIV DFVLKNLGGP GEGGAGPREE PLPPAPPLAN GSQPPQGLPP NPADPTRTFA 2170 2180 2190 2200 2210 2220 WLPGPPGVRV LSLGPAPEPP KPAASKIILV NKLGQVFVKM AGEGEPVSPP VKPPPLPPPM 2230 2240 2250 2260 2270 2280 PPTAPTSWTL PPGPLLGVLP VVGVVRPAPP PPPPPLTLVL SSGPPSPPRQ AIRVKRVSTF 2290 2300 2310 2320 2330 2340 SGRSPPAPPP SKTPRLEEDG ESLEDPPQGP GPCGSGFSRV RMKTPTVRGV LDLDDSGELT 2350 2360 2370 2380 2390 2400 AEESPRPLQD RSPLLPLPEG GPPRAPDGPP DLLLESQWHH YSGEASSSEE EPPSPEDKEN 2410 2420 2430 2440 2450 2460 QAPKRAGPHL RFEISSEDGF SVEAESLEGA WRTLIEKVQE ARGHARLRHL SFSGMSGARL 2470 2480 2490 2500 2510 2520 LGIHHDAVIF LAEQLPGAQR CQHYKFRYHQ QGEGQEEPPL NPHGAARAEV YLRKCTFDMF 2530 2540 2550 2560 2570 2580 NFLASQHRVL PEGATCDEEE DEVQLRSTRR ATSLELPMAM RFRHLKKTSK EAVGVYRSAI 2590 2600 2610 2620 2630 2640 HGRGLFCKRN IDAGEMVIEY SGIVIRSVLT DKREKFYDGK GIGCYMFRMD DFDVVDATMH 2650 2660 2670 2680 2690 2700 GNAARFINHS CEPNCFSRVI HVEGQKHIVI FALRRILRGE ELTYDYKFPI EDASNKLPCN 2710 CGAKRCRRFL N

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A whole-genome assembly of the domestic cow, Bos taurus." Zimin A.V., Delcher A.L., Florea L., Kelley D.R., Schatz M.C., Puiu D., Hanrahan F., Pertea G., Van Tassell C.P., Sonstegard T.S., Marcais G., Roberts M., Subramanian P., Yorke J.A., Salzberg S.L. Genome Biol. 10:R42-R42(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Hereford Ensembl ENSBTAP00000003584.
[2]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: Hereford Ensembl ENSBTAP00000003584.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DAAA02046952 Genomic DNA. No translation available.
IPI	IPI00691914.
RefSeq	XP_003587289.1. XM_003587241.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSBTAT00000003584; ENSBTAP00000003584; ENSBTAG00000002763.
GeneID	785776.
KEGG	bta:785776.
Phylogenomic databases
GeneTree	ENSGT00690000101661.
KO	K14959.
OMA	RTGSWKC.
Family and domain databases
Gene3D	3.30.40.10. 2 hits.
InterPro	IPR017956. AT_hook_DNA-bd_motif. IPR003889. FYrich_C. IPR003888. FYrich_N. IPR015722. Histone-lysine_MeTfrase. IPR003616. Post-SET_dom. IPR001214. SET_dom. IPR002857. Znf_CXXC. IPR011011. Znf_FYVE_PHD. IPR001965. Znf_PHD. IPR019787. Znf_PHD-finger. IPR013083. Znf_RING/FYVE/PHD. [Graphical view]
PANTHER	PTHR22884:SF10. PTHR22884:SF10. 1 hit.
Pfam	PF05965. FYRC. 1 hit. PF05964. FYRN. 1 hit. PF00628. PHD. 2 hits. PF00856. SET. 1 hit. PF02008. zf-CXXC. 1 hit. [Graphical view]
SMART	SM00384. AT_hook. 5 hits. SM00542. FYRC. 1 hit. SM00541. FYRN. 1 hit. SM00249. PHD. 4 hits. SM00508. PostSET. 1 hit. SM00317. SET. 1 hit. [Graphical view]
SUPFAM	SSF57903. FYVE_PHD_ZnF. 2 hits.
PROSITE	PS51543. FYRC. 1 hit. PS51542. FYRN. 1 hit. PS50868. POST_SET. 1 hit. PS50280. SET. 1 hit. PS51058. ZF_CXXC. 1 hit. PS50016. ZF_PHD_2. 3 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

E1BKN0_BOVIN

Accession

Primary (citable) accession number: E1BKN0

Entry history

Integrated into UniProtKB/TrEMBL:	November 2, 2010
Last sequence update:	November 16, 2011
Last modified:	April 3, 2013
This is version 26 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)