SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

E1BKN0

- E1BKN0_BOVIN

UniProt

E1BKN0 - E1BKN0_BOVIN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name:

Uncharacterized protein

Gene
KMT2B
Organism
Bos taurus (Bovine)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].SAAS annotations

GO - Molecular functioni

  1. DNA binding Source: InterPro
  2. histone methyltransferase activity (H3-K4 specific) Source: Ensembl
  3. zinc ion binding Source: InterPro

GO - Biological processi

  1. gene silencing Source: Ensembl
  2. histone H3-K4 trimethylation Source: Ensembl
  3. oocyte differentiation Source: Ensembl
  4. ovarian follicle development Source: Ensembl
  5. ovulation Source: Ensembl
  6. regulation of histone H3-K4 methylation Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotationSAAS annotations, Transferase

Keywords - Ligandi

Metal-binding, S-adenosyl-L-methionineSAAS annotations, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:KMT2BImported
OrganismiBos taurus (Bovine)Imported
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
ProteomesiUP000009136: Chromosome 18

Subcellular locationi

GO - Cellular componenti

  1. histone methyltransferase complex Source: Ensembl
Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotations

Family & Domainsi

Sequence similaritiesi

Contains 1 SET domain.UniRule annotation
Contains SET domain.SAAS annotations
Contains post-SET domain.SAAS annotations

Keywords - Domaini

Zinc-fingerSAAS annotations

Phylogenomic databases

GeneTreeiENSGT00740000115089.
KOiK14959.
OMAiWTSLTRE.
OrthoDBiEOG73RBBN.
TreeFamiTF319820.

Family and domain databases

Gene3Di3.30.40.10. 2 hits.
InterProiIPR017956. AT_hook_DNA-bd_motif.
IPR003889. FYrich_C.
IPR003888. FYrich_N.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
IPR002857. Znf_CXXC.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR019787. Znf_PHD-finger.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamiPF05965. FYRC. 1 hit.
PF05964. FYRN. 1 hit.
PF00628. PHD. 2 hits.
PF00856. SET. 1 hit.
PF02008. zf-CXXC. 1 hit.
[Graphical view]
SMARTiSM00384. AT_hook. 5 hits.
SM00542. FYRC. 1 hit.
SM00541. FYRN. 1 hit.
SM00249. PHD. 4 hits.
SM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
SUPFAMiSSF57903. SSF57903. 2 hits.
PROSITEiPS51543. FYRC. 1 hit.
PS51542. FYRN. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
PS51058. ZF_CXXC. 1 hit.
PS50016. ZF_PHD_2. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E1BKN0-1 [UniParc]FASTAAdd to Basket

« Hide

MAAAAGGGSC PGPGSARGRF PGRPRGSGGG GGRGGRGNGA ERVRVALRRG     50
GGAAGPGGAE PGEDTALLRL LGLHRGLRRL RRLWAGPRIQ RGRGRGRGRG 100
WGPSRGCLLE EESSDGESDD EEFQGFHSDE DAASSSLRSA LRSQRGRAPR 150
GRGRKHKTTP LPPPRLADVA PAPPKTPARK RGEEGTERMV QALTELLRRA 200
QAPPAPRSRA CESSTPRRSR GRPPGRPAGP CRKKQQAVVV AEAAVTIPRP 250
EPPPPVVPVK HRTGSWKCKE GPGPGPGTPK RGGQSGRGGR GGRGRGRGRL 300
PLVIKFVSKA KKMKMGQLSL GLESGQGQDQ HEESWQDAPQ GRVGSGQGEG 350
PCWRKEQKLE EEGEEEKEEE DEEEERAVAE EAMVLAEEKE EAKLPSPPLT 400
PPAPPPPPSL PPASASPPSP LCPPPPPVSP PPPPTPPPPR APEEQEESPP 450
PVVPATCSRK RGRPPLTPSQ RAEREAARAG PEGTSPPTPV PSTATGGPLE 500
DSPTVAPKST TFLKNIRQFI MPVVSARSSR VIKTPRRFMD EDPPKPPKVE 550
VSPTLRPPIA TSPLAPQEPA PAPSPPRAPT PPSTPVPLPE KRRSILREPT 600
FRWTSLTREL PPPPPAPPPA PPPLPAPVTP SRRPLLLRAP QFTPSEAHLK 650
IYESVLTTPP LGAPEAPEPE PPPADDSPAE PEPRALGRTN HLSLPRFAPV 700
VATPIKAEMP SPGAPAPSSG QQPHAQLQQP LQALQTQLLP PALPPQQSLL 750
QPQLQLQPPP QQAPPLEKAR IAGLGSLPLS GVEEKMFSLL KRAKVQLIKI 800
DQQQQQKVAS LMPPSPGGQM EEVVGTVKQI PDRGSVKSED ESVETKRERP 850
SGPESPVQGP RIKHVCRHAA VALGQARAMV PEDVPRLSAL PLRDRQDLNA 900
EDTSSASETE SVPSQSQPGK VESTGPGGDS EPAGSGGTLA HAPRRSLPSH 950
HGKKMRMARC GHCRGCLRVQ DCGSCVNCLD KPKFGGPNTK KQCCVYRKCD 1000
KIEARKMERL AKKGRTIVKT LLPWDSDESP EASPGPPGPR RGAGAGGPRE 1050
EVVAPPGPEE QDSFLLQRKS ARRCVKQRPS YDIFEDSDDS DPGGPPAPRR 1100
RTPRENELPV PEPEEQSRPR KPTLQPVLQL KARRRLDKDA LAPGPFASFP 1150
NGWTGKQKSP DGVHRVRVDF KEDCDLENVW LMGGLSVLTS VPGGPPMVCL 1200
LCASKGLHEL VFCQVCCDPF HPFCLEEAER PLPQHHDTWC CRRCKFCHVC 1250
GRKGRGSKHL LECERCRHAY HPACLGPSYP TRATRKRRHW ICSACVRCKS 1300
CGATPGKNWD VEWSGDYSLC PRCTQLFEKG NYCPICTRCY EDNDYESKMM 1350
QCAQCDHWVH AKCEGLSDED YEILSGLPDS VLYTCGPCAG ATHPRWREAL 1400
SGALQGGLRQ VLQGLLSSKV AGPLLLCTQC GQEGQQLHPG PCDLHAVRRR 1450
FEEGHYKSVH SFMEDVVGIL MRHSEEGEML ERRAGGQTKG LLLKLLESAF 1500
GWFDAHDPKY WRRSTRLPNG VLPNAVLPPS LDHVYAQWRQ QEPETPESGQ 1550
PPGDPSTAFQ GKDSAAFSHL EDPRQCALCL KYGDADSKEA GRLLYIGQNE 1600
WTHVNCAIWS AEVFEENDGS LKNVHAAVAR GRQMRCELCL KPGATVGCCL 1650
SSCLSNFHFM CARASYCIFQ DDKKVFCQKH TDLLDGKEIV NPDGFDVLRR 1700
VYVDFEGINF KRKFLTGLEP DAINVLIGSI RIDSLGTLSD LSDCEGRLFP 1750
IGYQCSRLYW STVDARRRCW YRCRILEYRP WGPREEPVHL EAAEENQTIV 1800
HSPAPCSEPP DHVDPPPDTD ALIPRAPEHH PPVQNPDPPP RLDPSSAPPP 1850
APRSFSGARI KVPNYSPSRR PLGGVSFGPL PSPGSPSSLT HHIPTVGDPD 1900
FPAPPRRSRR PSPLASRLPP SRRASPPLRT SPQLRVPPPT SVVRALTPTS 1950
GELAPPSRAP SPPPPPEDLG PDFEDMEVVS GLSAADLDFA ASLLGTEPFQ 2000
EEIVAAGAGG SSHGGLGDSS EEEAGPTPRY VHFPVTVVSG PALAPGALPG 2050
APRIEQLDGV DDGTDSEAEA VQQPRGQGTP TSGPGAGRAG VIGAAGDRAR 2100
PPEDLPSEIV DFVLKNLGGP GEGGAGPREE PLPPAPPLAN GSQPPQGLPP 2150
NPADPTRTFA WLPGPPGVRV LSLGPAPEPP KPAASKIILV NKLGQVFVKM 2200
AGEGEPVSPP VKPPPLPPPM PPTAPTSWTL PPGPLLGVLP VVGVVRPAPP 2250
PPPPPLTLVL SSGPPSPPRQ AIRVKRVSTF SGRSPPAPPP SKTPRLEEDG 2300
ESLEDPPQGP GPCGSGFSRV RMKTPTVRGV LDLDDSGELT AEESPRPLQD 2350
RSPLLPLPEG GPPRAPDGPP DLLLESQWHH YSGEASSSEE EPPSPEDKEN 2400
QAPKRAGPHL RFEISSEDGF SVEAESLEGA WRTLIEKVQE ARGHARLRHL 2450
SFSGMSGARL LGIHHDAVIF LAEQLPGAQR CQHYKFRYHQ QGEGQEEPPL 2500
NPHGAARAEV YLRKCTFDMF NFLASQHRVL PEGATCDEEE DEVQLRSTRR 2550
ATSLELPMAM RFRHLKKTSK EAVGVYRSAI HGRGLFCKRN IDAGEMVIEY 2600
SGIVIRSVLT DKREKFYDGK GIGCYMFRMD DFDVVDATMH GNAARFINHS 2650
CEPNCFSRVI HVEGQKHIVI FALRRILRGE ELTYDYKFPI EDASNKLPCN 2700
CGAKRCRRFL N 2711
Length:2,711
Mass (Da):293,366
Last modified:November 16, 2011 - v2
Checksum:iBED4A79F7DA60E24
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DAAA02046952 Genomic DNA. No translation available.
RefSeqiXP_003587289.1. XM_003587241.2.

Genome annotation databases

EnsembliENSBTAT00000003584; ENSBTAP00000003584; ENSBTAG00000002763.
GeneIDi785776.
KEGGibta:785776.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DAAA02046952 Genomic DNA. No translation available.
RefSeqi XP_003587289.1. XM_003587241.2.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSBTAT00000003584 ; ENSBTAP00000003584 ; ENSBTAG00000002763 .
GeneIDi 785776.
KEGGi bta:785776.

Organism-specific databases

CTDi 9757.

Phylogenomic databases

GeneTreei ENSGT00740000115089.
KOi K14959.
OMAi WTSLTRE.
OrthoDBi EOG73RBBN.
TreeFami TF319820.

Family and domain databases

Gene3Di 3.30.40.10. 2 hits.
InterProi IPR017956. AT_hook_DNA-bd_motif.
IPR003889. FYrich_C.
IPR003888. FYrich_N.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
IPR002857. Znf_CXXC.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR019787. Znf_PHD-finger.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view ]
Pfami PF05965. FYRC. 1 hit.
PF05964. FYRN. 1 hit.
PF00628. PHD. 2 hits.
PF00856. SET. 1 hit.
PF02008. zf-CXXC. 1 hit.
[Graphical view ]
SMARTi SM00384. AT_hook. 5 hits.
SM00542. FYRC. 1 hit.
SM00541. FYRN. 1 hit.
SM00249. PHD. 4 hits.
SM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view ]
SUPFAMi SSF57903. SSF57903. 2 hits.
PROSITEi PS51543. FYRC. 1 hit.
PS51542. FYRN. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
PS51058. ZF_CXXC. 1 hit.
PS50016. ZF_PHD_2. 3 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HerefordImported.
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: HerefordImported.

Entry informationi

Entry nameiE1BKN0_BOVIN
AccessioniPrimary (citable) accession number: E1BKN0
Entry historyi
Integrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 16, 2011
Last modified: March 19, 2014
This is version 32 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

Similar proteinsi