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Protein

Palmitoyltransferase

Gene

ZDHHC17

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferaseUniRule annotationSAAS annotation, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
PalmitoyltransferaseUniRule annotation (EC:2.3.1.225UniRule annotation)
Gene namesi
Name:ZDHHC17Imported
OrganismiBos taurus (Bovine)Imported
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 5

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei357 – 379HelicalUniRule annotationAdd BLAST23
Transmembranei385 – 404HelicalUniRule annotationAdd BLAST20
Transmembranei487 – 508HelicalUniRule annotationAdd BLAST22
Transmembranei541 – 563HelicalUniRule annotationAdd BLAST23

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiE1BJK1.

Expressioni

Gene expression databases

BgeeiENSBTAG00000021756.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000028999.

Structurei

3D structure databases

ProteinModelPortaliE1BJK1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini64 – 277ANK_REP_REGIONInterPro annotationAdd BLAST214
Repeati89 – 121ANKPROSITE-ProRule annotationAdd BLAST33
Repeati123 – 155ANKPROSITE-ProRule annotationAdd BLAST33
Repeati156 – 188ANKPROSITE-ProRule annotationAdd BLAST33
Repeati189 – 222ANKPROSITE-ProRule annotationAdd BLAST34
Repeati224 – 256ANKPROSITE-ProRule annotationAdd BLAST33

Domaini

The DHHC domain is required for palmitoyltransferase activity.UniRule annotation

Sequence similaritiesi

Belongs to the DHHC palmitoyltransferase family.UniRule annotationSAAS annotation

Keywords - Domaini

ANK repeatPROSITE-ProRule annotation, Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0509. Eukaryota.
COG0666. LUCA.
COG5273. LUCA.
GeneTreeiENSGT00530000063074.
InParanoidiE1BJK1.
OMAiQAKGYDS.
OrthoDBiEOG091G056H.
TreeFamiTF317342.

Family and domain databases

CDDicd00204. ANK. 2 hits.
Gene3Di1.25.40.20. 2 hits.
InterProiView protein in InterPro
IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR001594. Palmitoyltrfase_DHHC.
IPR030289. ZDHHC17.
PANTHERiPTHR24161:SF39. PTHR24161:SF39. 1 hit.
PfamiView protein in Pfam
PF12796. Ank_2. 2 hits.
PF01529. DHHC. 1 hit.
PRINTSiPR01415. ANKYRIN.
SMARTiView protein in SMART
SM00248. ANK. 5 hits.
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiView protein in PROSITE
PS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 5 hits.

Sequencei

Sequence statusi: Complete.

E1BJK1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQREEGFNTK MADGPDEYES EAGCVPLLHP EEIKPQSHYN HGYGEPLGRK
60 70 80 90 100
THIDDYSTWD IVKATQYGIY ERCRELVEAG YDVRQPDKEN VTLLHWAAIN
110 120 130 140 150
NRIDLVKYYI SKGAIVDQLG GDLNSTPLHW ATRQGHLSMV VQLMKYGADP
160 170 180 190 200
SLIDGEGCSC IHLAAQFGHT SIVAYLIAKG QDVDMMDQNG MTPLMWAAYR
210 220 230 240 250
THSVDPTRLL LTFNVSVNLG DKYHKNTALH WAVLAGNTTV ISLLLEAGAN
260 270 280 290 300
VDAQNIKGES ALDLAKQRKN VWMINHLQEA RQAKGYDNPS FLRKLKADKE
310 320 330 340 350
FRQKVMLGTP FLVIWLVGFI ADLNIDSWLI KGLMYGGVWA TVQFLSKSFF
360 370 380 390 400
DHSMHSALPL GIYLATKFWM YVTWFFWFWN DAHLNFLFIH LPFLANSIAL
410 420 430 440 450
FYNFGKSWKS DPGIIKATEE QKKKTIVELA ETGSLDLSIF CSTCLIRKPV
460 470 480 490 500
RSKHCGVCNR CIAKFDHHCP WVGNCVGAGN HRYFMGYLFF LLFMICWMIY
510 520 530 540 550
GCISYWGLHC ETSYTKDGFW TYITQIATCS PWMFWMFLNS VFHFMWVAVL
560 570 580 590 600
LMCQMYQISC LGITTNERMN ARRYKHFKVT TTSIESPFNH GCVRNIIDFF
610 620 630
EFRCCGLFRP VIVDWTRQYT IEYDQISGSG YQLV
Length:634
Mass (Da):72,848
Last modified:November 2, 2010 - v1
Checksum:i8E17AA2790679CAC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02012384 Genomic DNA. No translation available.
DAAA02012385 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSBTAT00000028999; ENSBTAP00000028999; ENSBTAG00000021756.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiE1BJK1_BOVIN
AccessioniPrimary (citable) accession number: E1BJK1
Entry historyiIntegrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 2, 2010
Last modified: July 5, 2017
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported