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E1BIN8

- E1BIN8_BOVIN

UniProt

E1BIN8 - E1BIN8_BOVIN

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Protein
Submitted name:

Uncharacterized protein

Gene
HBEGF
Organism
Bos taurus (Bovine)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. heparin binding Source: Ensembl

GO - Biological processi

  1. epidermal growth factor receptor signaling pathway Source: Ensembl
  2. positive regulation of keratinocyte migration Source: Ensembl
  3. positive regulation of protein kinase B signaling Source: Ensembl
  4. positive regulation of smooth muscle cell proliferation Source: Ensembl
  5. positive regulation of wound healing Source: Ensembl
  6. regulation of heart contraction Source: Ensembl
  7. wound healing, spreading of epidermal cells Source: Ensembl
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_206968. GRB2 events in ERBB2 signaling.
REACT_208171. PIP3 activates AKT signaling.
REACT_211997. SHC1 events in ERBB2 signaling.
REACT_215895. Constitutive PI3K/AKT Signaling in Cancer.
REACT_216183. Signaling by ERBB4.
REACT_218958. Signaling by ERBB2.
REACT_219416. PI3K events in ERBB2 signaling.
REACT_220588. Nuclear signaling by ERBB4.
REACT_222492. PI3K events in ERBB4 signaling.
REACT_222894. EGFR Transactivation by Gastrin.
REACT_223442. SHC1 events in ERBB4 signaling.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:HBEGFImported
OrganismiBos taurus (Bovine)Imported
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
ProteomesiUP000009136: Chromosome 7

Subcellular locationi

GO - Cellular componenti

  1. cell surface Source: Ensembl
  2. extracellular space Source: Ensembl
  3. integral component of plasma membrane Source: Ensembl
Complete GO annotation...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00530000063708.
KOiK08523.
OMAiYSYDHTT.
OrthoDBiEOG7VQJGP.
TreeFamiTF332773.

Family and domain databases

InterProiIPR000742. EG-like_dom.
IPR013032. EGF-like_CS.
IPR015497. EGF_rcpt_ligand.
[Graphical view]
PANTHERiPTHR10740. PTHR10740. 1 hit.
SMARTiSM00181. EGF. 1 hit.
[Graphical view]
PROSITEiPS00022. EGF_1. 1 hit.
PS01186. EGF_2. 1 hit.
PS50026. EGF_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E1BIN8-1 [UniParc]FASTAAdd to Basket

« Hide

MKLLPSVVLK LFLAAVLSAL VTGESLERLR RGLAAGTSNL DTPTQSTDQL    50
LPAGGGQGRE VLDLEEANLD LFRAAFSSKP QALATPSKEE RGKRKKKGKG 100
LGKKRNPCLR RYKDFCIHGE CKYVKELRVP TCICHPGYHG ERCHGLSLPV 150
KNRLYTYDHT TILVVVAVVL SSVCLLVIMG LLMFWYHRRG GYDVENEEKV 200
KLGMTTSH 208
Length:208
Mass (Da):23,093
Last modified:November 2, 2010 - v1
Checksum:iB73E5A104B563B77
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DAAA02020430 Genomic DNA. No translation available.
RefSeqiNP_001137562.1. NM_001144090.1.
UniGeneiBt.14152.

Genome annotation databases

EnsembliENSBTAT00000029015; ENSBTAP00000029015; ENSBTAG00000021766.
GeneIDi522921.
KEGGibta:522921.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DAAA02020430 Genomic DNA. No translation available.
RefSeqi NP_001137562.1. NM_001144090.1.
UniGenei Bt.14152.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSBTAT00000029015 ; ENSBTAP00000029015 ; ENSBTAG00000021766 .
GeneIDi 522921.
KEGGi bta:522921.

Organism-specific databases

CTDi 1839.

Phylogenomic databases

GeneTreei ENSGT00530000063708.
KOi K08523.
OMAi YSYDHTT.
OrthoDBi EOG7VQJGP.
TreeFami TF332773.

Enzyme and pathway databases

Reactomei REACT_206968. GRB2 events in ERBB2 signaling.
REACT_208171. PIP3 activates AKT signaling.
REACT_211997. SHC1 events in ERBB2 signaling.
REACT_215895. Constitutive PI3K/AKT Signaling in Cancer.
REACT_216183. Signaling by ERBB4.
REACT_218958. Signaling by ERBB2.
REACT_219416. PI3K events in ERBB2 signaling.
REACT_220588. Nuclear signaling by ERBB4.
REACT_222492. PI3K events in ERBB4 signaling.
REACT_222894. EGFR Transactivation by Gastrin.
REACT_223442. SHC1 events in ERBB4 signaling.

Miscellaneous databases

NextBioi 20873626.

Family and domain databases

InterProi IPR000742. EG-like_dom.
IPR013032. EGF-like_CS.
IPR015497. EGF_rcpt_ligand.
[Graphical view ]
PANTHERi PTHR10740. PTHR10740. 1 hit.
SMARTi SM00181. EGF. 1 hit.
[Graphical view ]
PROSITEi PS00022. EGF_1. 1 hit.
PS01186. EGF_2. 1 hit.
PS50026. EGF_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HerefordImported.
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: HerefordImported.

Entry informationi

Entry nameiE1BIN8_BOVIN
AccessioniPrimary (citable) accession number: E1BIN8
Entry historyi
Integrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 2, 2010
Last modified: September 3, 2014
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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