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E1BGA4

- E1BGA4_BOVIN

UniProt

E1BGA4 - E1BGA4_BOVIN

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Protein
Submitted name:

Uncharacterized protein

Gene

ASH1L

Organism
Bos taurus (Bovine)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].SAAS annotation

GO - Molecular functioni

  1. chromatin binding Source: InterPro
  2. DNA binding Source: InterPro
  3. histone-lysine N-methyltransferase activity Source: InterPro
  4. zinc ion binding Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotationSAAS annotation, Transferase

Keywords - Ligandi

Metal-binding, S-adenosyl-L-methionineSAAS annotation, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:ASH1LImported
OrganismiBos taurus (Bovine)Imported
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
ProteomesiUP000009136: Chromosome 3

Subcellular locationi

GO - Cellular componenti

  1. extracellular vesicular exosome Source: Ensembl
  2. Golgi apparatus Source: Ensembl
  3. nucleus Source: InterPro
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiE1BGA4.

Family & Domainsi

Sequence similaritiesi

Contains 1 SET domain.UniRule annotation
Contains 1 post-SET domain.
Contains SET domain.SAAS annotation
Contains post-SET domain.SAAS annotation

Keywords - Domaini

Zinc-fingerSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00770000120575.
InParanoidiE1BGA4.
KOiK06101.
OMAiPENSFRK.
OrthoDBiEOG7ZPNJ4.
TreeFamiTF106416.

Family and domain databases

Gene3Di1.20.920.10. 1 hit.
3.30.40.10. 1 hit.
InterProiIPR017956. AT_hook_DNA-bd_motif.
IPR006560. AWS_dom.
IPR001025. BAH_dom.
IPR001487. Bromodomain.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
IPR019786. Zinc_finger_PHD-type_CS.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR019787. Znf_PHD-finger.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamiPF01426. BAH. 1 hit.
PF00439. Bromodomain. 1 hit.
PF00628. PHD. 1 hit.
PF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00384. AT_hook. 4 hits.
SM00570. AWS. 1 hit.
SM00439. BAH. 1 hit.
SM00297. BROMO. 1 hit.
SM00249. PHD. 1 hit.
SM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
SUPFAMiSSF47370. SSF47370. 1 hit.
SSF57903. SSF57903. 1 hit.
PROSITEiPS51215. AWS. 1 hit.
PS51038. BAH. 1 hit.
PS50014. BROMODOMAIN_2. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
PS01359. ZF_PHD_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E1BGA4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDPRNTAMLG LGSDSEGFSR KSPSAINTGT LVSKREVELE NNTKEEEDLR
60 70 80 90 100
KWNRERNTEA GKDNGLTDAQ QQFSVKETNF TEGNLKLKIG LQAKRTKKPP
110 120 130 140 150
KNLENYVCRP AIKTTIKHPR KALKSGKMTD EKNEHCPSRR DPSKLYKKSG
160 170 180 190 200
DVAAIECQSE ETIHLHSQGE NSPLSKKLSP VHSEMTDYIN ATSSTLVGSR
210 220 230 240 250
DPDLKDRALL NGGTSVTEKL AQLIATCPPS KSSKTKPKKL ATGTTAGLVS
260 270 280 290 300
KDLIRKAGVG SVAGIIHKDL IKKPTISTAV GLVTKDPGKK PVFNATVGLV
310 320 330 340 350
NKDSVKKLGT GTTTVFINKD LGKKPGAITT VGLLSKDTGK KLGIGIVPGL
360 370 380 390 400
VNKEPGKKLG LGTVVGLVNK DLGKKLGSTV GLVAKDCAKK IVANSTVGLV
410 420 430 440 450
NKDIGKKLVS CPMTGLVNKD AINLKAEALL PTQEPLKASC STNIISHESQ
460 470 480 490 500
DLSESLKDGA TSKTFEKNVT RQSKESILEK FSVRKEIINL EKEMFNEGTC
510 520 530 540 550
IQQDSFSSSE RGSYETSKHE KQPPVYCTSP DFQMGVASDA STAKSPFSAV
560 570 580 590 600
GESNLPSPSP TVSVNPLSRS PPETSSQMTP NPLLLSPTTE LMEEISESVG
610 620 630 640 650
KNQFTSESTH LNIGHRSMGH SMNIECKGID KELNDSKTTH IDISRINSSL
660 670 680 690 700
GKKPSLTSES SIHTITPSVV NFTSLFSNKP FLKLGAVSAS DKHCQVAESL
710 720 730 740 750
STTLQSKPLK KRKGRKPRWT KVVARSTCRS PKGLELERSE LFKNVTCSSL
760 770 780 790 800
SNSNSEPAKF MKNIGPSSFV DHDFLKRRLP KLSKSTAPSL ALLTDSEKPS
810 820 830 840 850
HKSFATHKLS SSMCVSSDLL SDIYKPKRGR PKSKEMPQLE GPPKRTLKIP
860 870 880 890 900
ASKVFSLQSK EEQEPPILQP EIEIPSFKQS LSVSPFPKKR GRPKRQMRSP
910 920 930 940 950
VKMKPPVLSV APFVATESPS KLESESDNHR SSSDFFESED QLQDPDDLDD
960 970 980 990 1000
SHRPTVCSMS DLEMEPDKKI TKRNNGQLMK TIIRKINKMK TLKRKKLLNQ
1010 1020 1030 1040 1050
ILSSSVESSN KGKVQSKLHN TVSSLAATFG SKLGQQINVS KKGTIYIGKR
1060 1070 1080 1090 1100
RGRKPKTVLN GILSGSPTSL AVLEQTAQQA AGSALGQILP PLLPSSASSS
1110 1120 1130 1140 1150
EILPSPICSQ SSGTSGGQSP VSSDAGFVEP SSVPYLHLHS RQGSMIQTLA
1160 1170 1180 1190 1200
MKKASKGRRR LSPPTLLPNS PSHLSELTSL KEATPSPISE SHSDETIPSD
1210 1220 1230 1240 1250
SGIGTDNNST SDRAEKFCGQ KKRRHSFEHV SLIPPETSTV LSSLKEKHKH
1260 1270 1280 1290 1300
KCKRRNHDYL SYDKMKRQKR KRKKKYPQLR NRQDPDFIAD LEELISRLSE
1310 1320 1330 1340 1350
IRITHRSHHF IPRDLLPTIF RINFNSFYTH PSFPLDPLHY IRKPDLKKKR
1360 1370 1380 1390 1400
GRPPKMREAM AEMPFMHSLS FPLSSTGFYP SYGMPYSPSP LTAAPIGLGY
1410 1420 1430 1440 1450
YGRYPPTLYP PPPSPSFTTP LPPPSYMHAG HLLLNPTKYH KKKHKLLRQE
1460 1470 1480 1490 1500
AFLTTSRTPL LSMSTYPSVP PEMAYGWMVE HKHRHRHKHR EHRSSEQPQV
1510 1520 1530 1540 1550
SMDAGSSRSV LESLKRYRFG KDTVGERYKH KEKHRCHMSC PHLSPSKSLI
1560 1570 1580 1590 1600
NREEQWVHRE PSESSPLALG LQTPLQIDCS ESSPSLSLGG FTPNSDPASS
1610 1620 1630 1640 1650
DEHTNLFTSA IGSCRVSNPN SSGRKKLTDS PGLFSAQDTS LNRPHRKEPL
1660 1670 1680 1690 1700
PSSERAVQTL TGSQPASDKS SQRPSESTNC SPARKRSSSE STSSTVNGVP
1710 1720 1730 1740 1750
SRSPRLVSSG DDSVDSLLQR MVQHEDQEPL EKNIDAVIAS ASVPPSSSPV
1760 1770 1780 1790 1800
HSLSKERTLG KPDSLLVPAV PSDSCSSSIS LLSEKLPSSH SPHHIKRSVV
1810 1820 1830 1840 1850
EAMQRQARKM CNYDKILATK KNLDHVNKIL KAKKLQRQAR TGNNFVKRRP
1860 1870 1880 1890 1900
GRPRKCPLQA VVSMQAFQAA QFVGSELNEG EEGTALHLGP DTVTDVIEAV
1910 1920 1930 1940 1950
VQSVNLNPDH KKGLKRKSWL LEEQTKKKQK PFPEEEEEEE NAKSFTEAAV
1960 1970 1980 1990 2000
EIPSPPETPA KPPEPESTLQ PVLSLIPREK KAPRPPKKKY QKAGLYSDVY
2010 2020 2030 2040 2050
KTTDPKSRLI QLKKEKLEYT PGEHEYGLFP APIHVGKYLR QKRIDFQLPY
2060 2070 2080 2090 2100
DILWQWKHNQ LYKKPDVPLY KKIRSNVYVD VKPLSGYEAT TCNCKKPDDD
2110 2120 2130 2140 2150
TKKGCVDDCL NRMIFAECSP NTCPCGEQCC NQRIQRHEWV QCLERFRAEE
2160 2170 2180 2190 2200
KGWGIRTKEP LKAGQFIIEY LGEVVSEQEF RNRMIEQYHN HSDHYCLNLD
2210 2220 2230 2240 2250
SGMVIDSYRM GNEARFINHS CDPNCEMQKW SVNGVYRIGL YALKDMPAGT
2260 2270 2280 2290 2300
ELTYDYNFHS FNVEKQQLCK CGFEKCRGII GGKSQRMNGL TSNKSSQPVT
2310 2320 2330 2340 2350
SHKKSGRSKE KRKSKHKLKK RRGHLSEEPS ENINTPTRLT PQLQMKPMSN
2360 2370 2380 2390 2400
RERNFVLKHH VFLVRNWEKI RQKQEEVKHT SDNIHSASLY TRWNGICRDD
2410 2420 2430 2440 2450
GNIKSDVFMT QFSALQTARS VRTRRLAAAE ENIEVARAAR LAQIFKEICD
2460 2470 2480 2490 2500
GIISYKDSSR QSLAAPLLNL PPKKKNADYY EKISDPLDLS TIEKQILIGY
2510 2520 2530 2540 2550
YKTVEAFDAD MLKVFRNAEK YYGRKSPVGR DVCRLRKAYY NARHEASAQI
2560 2570 2580 2590 2600
DEIVGETASE ADSSETSVSE KENGHEKDDD VIRCICGLYK DEGLMIQCDK
2610 2620 2630 2640 2650
CMVWQHCDCM GVNSDVEHYL CEQCDPRPVD REVPMIPRPH YTQPGCVYFI
2660 2670 2680 2690 2700
CLLRDDLLLR QGDCVYLMRD SRRTPDGHPV RQSYRLLSHI NRDKLDIFRI
2710 2720 2730 2740 2750
EKLWKNEKEE RFAFGHHYFR PHETHHSPSR RFYHNELFRV PLYEIIPLEA
2760 2770 2780 2790 2800
VVGTCCVLDL YTYCKGRPKG VKEQDVYICD YRLDKSAHLF YKIHRNRYPV
2810 2820 2830 2840 2850
CTKPYAFDHF PKKLTPKRDF SPHYVPDNYK RNGGRSSWKS ERSKPPLKDL
2860 2870 2880 2890 2900
GQEDDALPLI EEVLASQEQA ANEMPSLEEP EREGATAENS ESEKKKEESS
2910 2920 2930 2940 2950
QEPQVACTPE ERRHNQRERL NQILLNLLEK IPGKNAIDVT YLLEEGSGRK
2960
LRRRTLFIPE NSFRK
Length:2,965
Mass (Da):332,556
Last modified:November 2, 2010 - v1
Checksum:iE5FEA55F49BA1548
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02007153 Genomic DNA. No translation available.
DAAA02007154 Genomic DNA. No translation available.
DAAA02007155 Genomic DNA. No translation available.
RefSeqiNP_001179672.1. NM_001192743.1.
XP_005203800.1. XM_005203743.1.
UniGeneiBt.58583.

Genome annotation databases

EnsembliENSBTAT00000005172; ENSBTAP00000005172; ENSBTAG00000003954.
GeneIDi540563.
KEGGibta:540563.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02007153 Genomic DNA. No translation available.
DAAA02007154 Genomic DNA. No translation available.
DAAA02007155 Genomic DNA. No translation available.
RefSeqi NP_001179672.1. NM_001192743.1.
XP_005203800.1. XM_005203743.1.
UniGenei Bt.58583.

3D structure databases

ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi E1BGA4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSBTAT00000005172 ; ENSBTAP00000005172 ; ENSBTAG00000003954 .
GeneIDi 540563.
KEGGi bta:540563.

Organism-specific databases

CTDi 55870.

Phylogenomic databases

GeneTreei ENSGT00770000120575.
InParanoidi E1BGA4.
KOi K06101.
OMAi PENSFRK.
OrthoDBi EOG7ZPNJ4.
TreeFami TF106416.

Miscellaneous databases

NextBioi 20878704.

Family and domain databases

Gene3Di 1.20.920.10. 1 hit.
3.30.40.10. 1 hit.
InterProi IPR017956. AT_hook_DNA-bd_motif.
IPR006560. AWS_dom.
IPR001025. BAH_dom.
IPR001487. Bromodomain.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
IPR019786. Zinc_finger_PHD-type_CS.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR019787. Znf_PHD-finger.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view ]
Pfami PF01426. BAH. 1 hit.
PF00439. Bromodomain. 1 hit.
PF00628. PHD. 1 hit.
PF00856. SET. 1 hit.
[Graphical view ]
SMARTi SM00384. AT_hook. 4 hits.
SM00570. AWS. 1 hit.
SM00439. BAH. 1 hit.
SM00297. BROMO. 1 hit.
SM00249. PHD. 1 hit.
SM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view ]
SUPFAMi SSF47370. SSF47370. 1 hit.
SSF57903. SSF57903. 1 hit.
PROSITEi PS51215. AWS. 1 hit.
PS51038. BAH. 1 hit.
PS50014. BROMODOMAIN_2. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
PS01359. ZF_PHD_1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HerefordImported.
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: HerefordImported.

Entry informationi

Entry nameiE1BGA4_BOVIN
AccessioniPrimary (citable) accession number: E1BGA4
Entry historyi
Integrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 2, 2010
Last modified: November 26, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3