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E1BGA4

- E1BGA4_BOVIN

UniProt

E1BGA4 - E1BGA4_BOVIN

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Protein
Submitted name: Uncharacterized protein
Gene
ASH1L
Organism
Bos taurus (Bovine)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].SAAS annotations

GO - Molecular functioni

  1. DNA binding Source: InterPro
  2. chromatin binding Source: InterPro
  3. histone-lysine N-methyltransferase activity Source: InterPro
  4. zinc ion binding Source: InterPro
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    MethyltransferaseUniRule annotation, Transferase

    Keywords - Ligandi

    Metal-binding, Zinc

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Uncharacterized proteinImported
    Gene namesi
    Name:ASH1LImported
    OrganismiBos taurus (Bovine)Imported
    Taxonomic identifieri9913 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
    ProteomesiUP000009136: Chromosome 3

    Subcellular locationi

    GO - Cellular componenti

    1. Golgi apparatus Source: Ensembl
    2. nucleus Source: Ensembl
    Complete GO annotation...

    PTM / Processingi

    Proteomic databases

    PRIDEiE1BGA4.

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 SET domain.
    Contains 1 post-SET domain.UniRule annotation
    Contains SET domain.SAAS annotations
    Contains post-SET domain.SAAS annotations

    Keywords - Domaini

    Zinc-fingerSAAS annotations

    Phylogenomic databases

    GeneTreeiENSGT00740000114921.
    KOiK06101.
    OMAiPENSFRK.
    OrthoDBiEOG7ZPNJ4.
    TreeFamiTF106416.

    Family and domain databases

    Gene3Di1.20.920.10. 1 hit.
    3.30.40.10. 1 hit.
    InterProiIPR017956. AT_hook_DNA-bd_motif.
    IPR006560. AWS.
    IPR001025. BAH_dom.
    IPR001487. Bromodomain.
    IPR003616. Post-SET_dom.
    IPR001214. SET_dom.
    IPR019786. Zinc_finger_PHD-type_CS.
    IPR011011. Znf_FYVE_PHD.
    IPR001965. Znf_PHD.
    IPR019787. Znf_PHD-finger.
    IPR013083. Znf_RING/FYVE/PHD.
    [Graphical view]
    PfamiPF01426. BAH. 1 hit.
    PF00439. Bromodomain. 1 hit.
    PF00628. PHD. 1 hit.
    PF00856. SET. 1 hit.
    [Graphical view]
    SMARTiSM00384. AT_hook. 4 hits.
    SM00570. AWS. 1 hit.
    SM00439. BAH. 1 hit.
    SM00297. BROMO. 1 hit.
    SM00249. PHD. 1 hit.
    SM00508. PostSET. 1 hit.
    SM00317. SET. 1 hit.
    [Graphical view]
    SUPFAMiSSF47370. SSF47370. 1 hit.
    SSF57903. SSF57903. 1 hit.
    PROSITEiPS51215. AWS. 1 hit.
    PS51038. BAH. 1 hit.
    PS50014. BROMODOMAIN_2. 1 hit.
    PS50868. POST_SET. 1 hit.
    PS50280. SET. 1 hit.
    PS01359. ZF_PHD_1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E1BGA4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDPRNTAMLG LGSDSEGFSR KSPSAINTGT LVSKREVELE NNTKEEEDLR     50
    KWNRERNTEA GKDNGLTDAQ QQFSVKETNF TEGNLKLKIG LQAKRTKKPP 100
    KNLENYVCRP AIKTTIKHPR KALKSGKMTD EKNEHCPSRR DPSKLYKKSG 150
    DVAAIECQSE ETIHLHSQGE NSPLSKKLSP VHSEMTDYIN ATSSTLVGSR 200
    DPDLKDRALL NGGTSVTEKL AQLIATCPPS KSSKTKPKKL ATGTTAGLVS 250
    KDLIRKAGVG SVAGIIHKDL IKKPTISTAV GLVTKDPGKK PVFNATVGLV 300
    NKDSVKKLGT GTTTVFINKD LGKKPGAITT VGLLSKDTGK KLGIGIVPGL 350
    VNKEPGKKLG LGTVVGLVNK DLGKKLGSTV GLVAKDCAKK IVANSTVGLV 400
    NKDIGKKLVS CPMTGLVNKD AINLKAEALL PTQEPLKASC STNIISHESQ 450
    DLSESLKDGA TSKTFEKNVT RQSKESILEK FSVRKEIINL EKEMFNEGTC 500
    IQQDSFSSSE RGSYETSKHE KQPPVYCTSP DFQMGVASDA STAKSPFSAV 550
    GESNLPSPSP TVSVNPLSRS PPETSSQMTP NPLLLSPTTE LMEEISESVG 600
    KNQFTSESTH LNIGHRSMGH SMNIECKGID KELNDSKTTH IDISRINSSL 650
    GKKPSLTSES SIHTITPSVV NFTSLFSNKP FLKLGAVSAS DKHCQVAESL 700
    STTLQSKPLK KRKGRKPRWT KVVARSTCRS PKGLELERSE LFKNVTCSSL 750
    SNSNSEPAKF MKNIGPSSFV DHDFLKRRLP KLSKSTAPSL ALLTDSEKPS 800
    HKSFATHKLS SSMCVSSDLL SDIYKPKRGR PKSKEMPQLE GPPKRTLKIP 850
    ASKVFSLQSK EEQEPPILQP EIEIPSFKQS LSVSPFPKKR GRPKRQMRSP 900
    VKMKPPVLSV APFVATESPS KLESESDNHR SSSDFFESED QLQDPDDLDD 950
    SHRPTVCSMS DLEMEPDKKI TKRNNGQLMK TIIRKINKMK TLKRKKLLNQ 1000
    ILSSSVESSN KGKVQSKLHN TVSSLAATFG SKLGQQINVS KKGTIYIGKR 1050
    RGRKPKTVLN GILSGSPTSL AVLEQTAQQA AGSALGQILP PLLPSSASSS 1100
    EILPSPICSQ SSGTSGGQSP VSSDAGFVEP SSVPYLHLHS RQGSMIQTLA 1150
    MKKASKGRRR LSPPTLLPNS PSHLSELTSL KEATPSPISE SHSDETIPSD 1200
    SGIGTDNNST SDRAEKFCGQ KKRRHSFEHV SLIPPETSTV LSSLKEKHKH 1250
    KCKRRNHDYL SYDKMKRQKR KRKKKYPQLR NRQDPDFIAD LEELISRLSE 1300
    IRITHRSHHF IPRDLLPTIF RINFNSFYTH PSFPLDPLHY IRKPDLKKKR 1350
    GRPPKMREAM AEMPFMHSLS FPLSSTGFYP SYGMPYSPSP LTAAPIGLGY 1400
    YGRYPPTLYP PPPSPSFTTP LPPPSYMHAG HLLLNPTKYH KKKHKLLRQE 1450
    AFLTTSRTPL LSMSTYPSVP PEMAYGWMVE HKHRHRHKHR EHRSSEQPQV 1500
    SMDAGSSRSV LESLKRYRFG KDTVGERYKH KEKHRCHMSC PHLSPSKSLI 1550
    NREEQWVHRE PSESSPLALG LQTPLQIDCS ESSPSLSLGG FTPNSDPASS 1600
    DEHTNLFTSA IGSCRVSNPN SSGRKKLTDS PGLFSAQDTS LNRPHRKEPL 1650
    PSSERAVQTL TGSQPASDKS SQRPSESTNC SPARKRSSSE STSSTVNGVP 1700
    SRSPRLVSSG DDSVDSLLQR MVQHEDQEPL EKNIDAVIAS ASVPPSSSPV 1750
    HSLSKERTLG KPDSLLVPAV PSDSCSSSIS LLSEKLPSSH SPHHIKRSVV 1800
    EAMQRQARKM CNYDKILATK KNLDHVNKIL KAKKLQRQAR TGNNFVKRRP 1850
    GRPRKCPLQA VVSMQAFQAA QFVGSELNEG EEGTALHLGP DTVTDVIEAV 1900
    VQSVNLNPDH KKGLKRKSWL LEEQTKKKQK PFPEEEEEEE NAKSFTEAAV 1950
    EIPSPPETPA KPPEPESTLQ PVLSLIPREK KAPRPPKKKY QKAGLYSDVY 2000
    KTTDPKSRLI QLKKEKLEYT PGEHEYGLFP APIHVGKYLR QKRIDFQLPY 2050
    DILWQWKHNQ LYKKPDVPLY KKIRSNVYVD VKPLSGYEAT TCNCKKPDDD 2100
    TKKGCVDDCL NRMIFAECSP NTCPCGEQCC NQRIQRHEWV QCLERFRAEE 2150
    KGWGIRTKEP LKAGQFIIEY LGEVVSEQEF RNRMIEQYHN HSDHYCLNLD 2200
    SGMVIDSYRM GNEARFINHS CDPNCEMQKW SVNGVYRIGL YALKDMPAGT 2250
    ELTYDYNFHS FNVEKQQLCK CGFEKCRGII GGKSQRMNGL TSNKSSQPVT 2300
    SHKKSGRSKE KRKSKHKLKK RRGHLSEEPS ENINTPTRLT PQLQMKPMSN 2350
    RERNFVLKHH VFLVRNWEKI RQKQEEVKHT SDNIHSASLY TRWNGICRDD 2400
    GNIKSDVFMT QFSALQTARS VRTRRLAAAE ENIEVARAAR LAQIFKEICD 2450
    GIISYKDSSR QSLAAPLLNL PPKKKNADYY EKISDPLDLS TIEKQILIGY 2500
    YKTVEAFDAD MLKVFRNAEK YYGRKSPVGR DVCRLRKAYY NARHEASAQI 2550
    DEIVGETASE ADSSETSVSE KENGHEKDDD VIRCICGLYK DEGLMIQCDK 2600
    CMVWQHCDCM GVNSDVEHYL CEQCDPRPVD REVPMIPRPH YTQPGCVYFI 2650
    CLLRDDLLLR QGDCVYLMRD SRRTPDGHPV RQSYRLLSHI NRDKLDIFRI 2700
    EKLWKNEKEE RFAFGHHYFR PHETHHSPSR RFYHNELFRV PLYEIIPLEA 2750
    VVGTCCVLDL YTYCKGRPKG VKEQDVYICD YRLDKSAHLF YKIHRNRYPV 2800
    CTKPYAFDHF PKKLTPKRDF SPHYVPDNYK RNGGRSSWKS ERSKPPLKDL 2850
    GQEDDALPLI EEVLASQEQA ANEMPSLEEP EREGATAENS ESEKKKEESS 2900
    QEPQVACTPE ERRHNQRERL NQILLNLLEK IPGKNAIDVT YLLEEGSGRK 2950
    LRRRTLFIPE NSFRK 2965
    Length:2,965
    Mass (Da):332,556
    Last modified:November 2, 2010 - v1
    Checksum:iE5FEA55F49BA1548
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DAAA02007153 Genomic DNA. No translation available.
    DAAA02007154 Genomic DNA. No translation available.
    DAAA02007155 Genomic DNA. No translation available.
    RefSeqiNP_001179672.1. NM_001192743.1.
    XP_005203800.1. XM_005203743.1.
    UniGeneiBt.58583.

    Genome annotation databases

    EnsembliENSBTAT00000005172; ENSBTAP00000005172; ENSBTAG00000003954.
    GeneIDi540563.
    KEGGibta:540563.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DAAA02007153 Genomic DNA. No translation available.
    DAAA02007154 Genomic DNA. No translation available.
    DAAA02007155 Genomic DNA. No translation available.
    RefSeqi NP_001179672.1. NM_001192743.1.
    XP_005203800.1. XM_005203743.1.
    UniGenei Bt.58583.

    3D structure databases

    ModBasei Search...

    Proteomic databases

    PRIDEi E1BGA4.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSBTAT00000005172 ; ENSBTAP00000005172 ; ENSBTAG00000003954 .
    GeneIDi 540563.
    KEGGi bta:540563.

    Organism-specific databases

    CTDi 55870.

    Phylogenomic databases

    GeneTreei ENSGT00740000114921.
    KOi K06101.
    OMAi PENSFRK.
    OrthoDBi EOG7ZPNJ4.
    TreeFami TF106416.

    Miscellaneous databases

    NextBioi 20878704.

    Family and domain databases

    Gene3Di 1.20.920.10. 1 hit.
    3.30.40.10. 1 hit.
    InterProi IPR017956. AT_hook_DNA-bd_motif.
    IPR006560. AWS.
    IPR001025. BAH_dom.
    IPR001487. Bromodomain.
    IPR003616. Post-SET_dom.
    IPR001214. SET_dom.
    IPR019786. Zinc_finger_PHD-type_CS.
    IPR011011. Znf_FYVE_PHD.
    IPR001965. Znf_PHD.
    IPR019787. Znf_PHD-finger.
    IPR013083. Znf_RING/FYVE/PHD.
    [Graphical view ]
    Pfami PF01426. BAH. 1 hit.
    PF00439. Bromodomain. 1 hit.
    PF00628. PHD. 1 hit.
    PF00856. SET. 1 hit.
    [Graphical view ]
    SMARTi SM00384. AT_hook. 4 hits.
    SM00570. AWS. 1 hit.
    SM00439. BAH. 1 hit.
    SM00297. BROMO. 1 hit.
    SM00249. PHD. 1 hit.
    SM00508. PostSET. 1 hit.
    SM00317. SET. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47370. SSF47370. 1 hit.
    SSF57903. SSF57903. 1 hit.
    PROSITEi PS51215. AWS. 1 hit.
    PS51038. BAH. 1 hit.
    PS50014. BROMODOMAIN_2. 1 hit.
    PS50868. POST_SET. 1 hit.
    PS50280. SET. 1 hit.
    PS01359. ZF_PHD_1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    « Hide 'large scale' publications
    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: HerefordImported.
    2. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: HerefordImported.

    Entry informationi

    Entry nameiE1BGA4_BOVIN
    AccessioniPrimary (citable) accession number: E1BGA4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 2, 2010
    Last sequence update: November 2, 2010
    Last modified: July 9, 2014
    This is version 30 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteome

    External Data

    Dasty 3

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