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E1BDU6

- E1BDU6_BOVIN

UniProt

E1BDU6 - E1BDU6_BOVIN

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Protein
Submitted name: Uncharacterized protein
Gene
ABCG1
Organism
Bos taurus (Bovine)
Status
Unreviewed - Annotation score: 4 out of 5 - Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. ADP binding Source: Ensembl
  2. ATP binding Source: UniProtKB-KW
  3. cholesterol transporter activity Source: Ensembl
  4. glycoprotein transporter activity Source: Ensembl
  5. phospholipid transporter activity Source: Ensembl
  6. sterol-transporting ATPase activity Source: Ensembl
  7. toxin transporter activity Source: Ensembl
Complete GO annotation...

GO - Biological processi

  1. amyloid precursor protein catabolic process Source: Ensembl
  2. cholesterol efflux Source: Ensembl
  3. cholesterol homeostasis Source: Ensembl
  4. cholesterol metabolic process Source: Ensembl
  5. high-density lipoprotein particle remodeling Source: Ensembl
  6. intracellular cholesterol transport Source: Ensembl
  7. low-density lipoprotein particle remodeling Source: Ensembl
  8. negative regulation of lipid storage Source: Ensembl
  9. phospholipid efflux Source: Ensembl
  10. phospholipid homeostasis Source: Ensembl
  11. positive regulation of cholesterol biosynthetic process Source: Ensembl
  12. positive regulation of cholesterol efflux Source: Ensembl
  13. regulation of cholesterol esterification Source: Ensembl
  14. regulation of transcription, DNA-templated Source: Ensembl
  15. response to high density lipoprotein particle Source: Ensembl
  16. response to lipid Source: Ensembl
  17. reverse cholesterol transport Source: Ensembl
Complete GO annotation...

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiREACT_222480. HDL-mediated lipid transport.
REACT_226243. ABCA transporters in lipid homeostasis.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:ABCG1Imported
OrganismiBos taurus (Bovine)Imported
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
ProteomesiUP000009136: Chromosome 1

Subcellular locationi

GO - Cellular componenti

  1. Golgi apparatus Source: Ensembl
  2. external side of plasma membrane Source: Ensembl
  3. integral component of membrane Source: InterPro
  4. mitochondrion Source: Ensembl
  5. recycling endosome Source: Ensembl
Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliE1BDU6.

Family & Domainsi

Sequence similaritiesi

Belongs to the ABC transporter superfamily.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00740000114855.
KOiK05679.
OMAiLECANTR.
OrthoDBiEOG7KWSGT.
TreeFamiTF105210.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR013525. ABC_2_trans.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR020064. ABCG1.
IPR027417. P-loop_NTPase.
IPR005284. Pigment_permease.
[Graphical view]
PANTHERiPTHR19241:SF177. PTHR19241:SF177. 1 hit.
PfamiPF01061. ABC2_membrane. 1 hit.
PF00005. ABC_tran. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00955. 3a01204. 1 hit.
PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E1BDU6-1 [UniParc]FASTAAdd to Basket

« Hide

MACLMATFSV GTAMNGSSGM TEPKSVCVSV DEVVFSNRDR DTVEKELLNG    50
HLKKEDNNLT EAQRLSSLPR RAAVNIEFKD LSYSVSEGPW WRKKGYKTLL 100
KGISGKFNSG ELVAIMGPSG AGKSTLMNIL AGYRETGMKG EVLINGLPRD 150
LRCFRKVSCY IMQDDLLLPH LTVQEAMMVS AHLKLQEKDE GRREMVKEIL 200
TALGLLSCAN TRTGSLSGGQ RKRLAIALEL VNNPPVMFFD EPTSGLDSAS 250
CFQVVSLMKG LAQGGRSIIC TIHQPSAKLF ELFDQLYVLS QGQCVYRGKV 300
SNLVPYLRDL GLNCPTYHNP ADFVMEVASG EYGDQNGRLV RAVWEGKCDS 350
DCRREPGGDA EVNPFIWHRP SEEDSTSMEG CHSFSASCLT QFCILFKRTF 400
LSIMRDSVLT HLRITSHIGI GLLIGLLYLG IGNEAKKVLS NSGFLFFSML 450
FLMFAALMPT VLTFPLEMSV FLREHLNYWY SLKAYYLAKT MADVPFQIMF 500
PVAYCSIVYW MTSQPSDAVR FVLFAALGTM TSLVAQSLGL LIGAASTSLQ 550
VATFVGPVTA IPVLLFSGFF VSFDTIPTYL QWMSYVSYVR YGFEGVILSI 600
YGLDREDLHC NTNETCHFQK SEAILRELDV ENAKLYLDFI VLGIFFISLR 650
LIAYLVLRYK IRAER 665
Length:665
Mass (Da):74,142
Last modified:November 2, 2010 - v1
Checksum:i710F7956734775FB
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DAAA02003260 Genomic DNA. No translation available.
RefSeqiXP_005202056.1. XM_005201999.1.
UniGeneiBt.29337.

Genome annotation databases

EnsembliENSBTAT00000028342; ENSBTAP00000028342; ENSBTAG00000021272.
GeneIDi510745.
KEGGibta:510745.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DAAA02003260 Genomic DNA. No translation available.
RefSeqi XP_005202056.1. XM_005201999.1.
UniGenei Bt.29337.

3D structure databases

ProteinModelPortali E1BDU6.
ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSBTAT00000028342 ; ENSBTAP00000028342 ; ENSBTAG00000021272 .
GeneIDi 510745.
KEGGi bta:510745.

Organism-specific databases

CTDi 9619.

Phylogenomic databases

GeneTreei ENSGT00740000114855.
KOi K05679.
OMAi LECANTR.
OrthoDBi EOG7KWSGT.
TreeFami TF105210.

Enzyme and pathway databases

Reactomei REACT_222480. HDL-mediated lipid transport.
REACT_226243. ABCA transporters in lipid homeostasis.

Miscellaneous databases

NextBioi 20869597.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
InterProi IPR003593. AAA+_ATPase.
IPR013525. ABC_2_trans.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR020064. ABCG1.
IPR027417. P-loop_NTPase.
IPR005284. Pigment_permease.
[Graphical view ]
PANTHERi PTHR19241:SF177. PTHR19241:SF177. 1 hit.
Pfami PF01061. ABC2_membrane. 1 hit.
PF00005. ABC_tran. 1 hit.
[Graphical view ]
SMARTi SM00382. AAA. 1 hit.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00955. 3a01204. 1 hit.
PROSITEi PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HerefordImported.
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: HerefordImported.

Entry informationi

Entry nameiE1BDU6_BOVIN
AccessioniPrimary (citable) accession number: E1BDU6
Entry historyi
Integrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 2, 2010
Last modified: September 3, 2014
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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