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E1BDU6

- E1BDU6_BOVIN

UniProt

E1BDU6 - E1BDU6_BOVIN

Protein
Submitted name:

Uncharacterized protein

Gene

ABCG1

Organism
Bos taurus (Bovine)
Status
Unreviewed - Annotation score: 4 out of 5- Protein inferred from homologyi
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    • History
      Entry version 31 (01 Oct 2014)
      Sequence version 1 (02 Nov 2010)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. ADP binding Source: Ensembl
    2. ATP binding Source: UniProtKB-KW
    3. cholesterol transporter activity Source: Ensembl
    4. glycoprotein transporter activity Source: Ensembl
    5. phospholipid transporter activity Source: Ensembl
    6. sterol-transporting ATPase activity Source: Ensembl
    7. toxin transporter activity Source: Ensembl

    GO - Biological processi

    1. amyloid precursor protein catabolic process Source: Ensembl
    2. cholesterol efflux Source: Ensembl
    3. cholesterol homeostasis Source: Ensembl
    4. cholesterol metabolic process Source: Ensembl
    5. high-density lipoprotein particle remodeling Source: Ensembl
    6. intracellular cholesterol transport Source: Ensembl
    7. low-density lipoprotein particle remodeling Source: Ensembl
    8. negative regulation of lipid storage Source: Ensembl
    9. phospholipid efflux Source: Ensembl
    10. phospholipid homeostasis Source: Ensembl
    11. positive regulation of cholesterol biosynthetic process Source: Ensembl
    12. positive regulation of cholesterol efflux Source: Ensembl
    13. regulation of cholesterol esterification Source: Ensembl
    14. regulation of transcription, DNA-templated Source: Ensembl
    15. response to high density lipoprotein particle Source: Ensembl
    16. response to lipid Source: Ensembl
    17. reverse cholesterol transport Source: Ensembl

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Enzyme and pathway databases

    ReactomeiREACT_222480. HDL-mediated lipid transport.
    REACT_226243. ABCA transporters in lipid homeostasis.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Uncharacterized proteinImported
    Gene namesi
    Name:ABCG1Imported
    OrganismiBos taurus (Bovine)Imported
    Taxonomic identifieri9913 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
    ProteomesiUP000009136: Chromosome 1

    Subcellular locationi

    GO - Cellular componenti

    1. external side of plasma membrane Source: Ensembl
    2. Golgi apparatus Source: Ensembl
    3. integral component of membrane Source: InterPro
    4. mitochondrion Source: Ensembl
    5. recycling endosome Source: Ensembl

    Structurei

    3D structure databases

    ProteinModelPortaliE1BDU6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ABC transporter superfamily.UniRule annotation

    Phylogenomic databases

    GeneTreeiENSGT00740000114855.
    KOiK05679.
    OMAiLECANTR.
    OrthoDBiEOG7KWSGT.
    TreeFamiTF105210.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    InterProiIPR003593. AAA+_ATPase.
    IPR013525. ABC_2_trans.
    IPR003439. ABC_transporter-like.
    IPR017871. ABC_transporter_CS.
    IPR020064. ABCG1.
    IPR027417. P-loop_NTPase.
    IPR005284. Pigment_permease.
    [Graphical view]
    PANTHERiPTHR19241:SF177. PTHR19241:SF177. 1 hit.
    PfamiPF01061. ABC2_membrane. 1 hit.
    PF00005. ABC_tran. 1 hit.
    [Graphical view]
    SMARTiSM00382. AAA. 1 hit.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00955. 3a01204. 1 hit.
    PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
    PS50893. ABC_TRANSPORTER_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E1BDU6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MACLMATFSV GTAMNGSSGM TEPKSVCVSV DEVVFSNRDR DTVEKELLNG    50
    HLKKEDNNLT EAQRLSSLPR RAAVNIEFKD LSYSVSEGPW WRKKGYKTLL 100
    KGISGKFNSG ELVAIMGPSG AGKSTLMNIL AGYRETGMKG EVLINGLPRD 150
    LRCFRKVSCY IMQDDLLLPH LTVQEAMMVS AHLKLQEKDE GRREMVKEIL 200
    TALGLLSCAN TRTGSLSGGQ RKRLAIALEL VNNPPVMFFD EPTSGLDSAS 250
    CFQVVSLMKG LAQGGRSIIC TIHQPSAKLF ELFDQLYVLS QGQCVYRGKV 300
    SNLVPYLRDL GLNCPTYHNP ADFVMEVASG EYGDQNGRLV RAVWEGKCDS 350
    DCRREPGGDA EVNPFIWHRP SEEDSTSMEG CHSFSASCLT QFCILFKRTF 400
    LSIMRDSVLT HLRITSHIGI GLLIGLLYLG IGNEAKKVLS NSGFLFFSML 450
    FLMFAALMPT VLTFPLEMSV FLREHLNYWY SLKAYYLAKT MADVPFQIMF 500
    PVAYCSIVYW MTSQPSDAVR FVLFAALGTM TSLVAQSLGL LIGAASTSLQ 550
    VATFVGPVTA IPVLLFSGFF VSFDTIPTYL QWMSYVSYVR YGFEGVILSI 600
    YGLDREDLHC NTNETCHFQK SEAILRELDV ENAKLYLDFI VLGIFFISLR 650
    LIAYLVLRYK IRAER 665
    Length:665
    Mass (Da):74,142
    Last modified:November 2, 2010 - v1
    Checksum:i710F7956734775FB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DAAA02003260 Genomic DNA. No translation available.
    RefSeqiXP_005202056.1. XM_005201999.1.
    UniGeneiBt.29337.

    Genome annotation databases

    EnsembliENSBTAT00000028342; ENSBTAP00000028342; ENSBTAG00000021272.
    GeneIDi510745.
    KEGGibta:510745.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DAAA02003260 Genomic DNA. No translation available.
    RefSeqi XP_005202056.1. XM_005201999.1.
    UniGenei Bt.29337.

    3D structure databases

    ProteinModelPortali E1BDU6.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSBTAT00000028342 ; ENSBTAP00000028342 ; ENSBTAG00000021272 .
    GeneIDi 510745.
    KEGGi bta:510745.

    Organism-specific databases

    CTDi 9619.

    Phylogenomic databases

    GeneTreei ENSGT00740000114855.
    KOi K05679.
    OMAi LECANTR.
    OrthoDBi EOG7KWSGT.
    TreeFami TF105210.

    Enzyme and pathway databases

    Reactomei REACT_222480. HDL-mediated lipid transport.
    REACT_226243. ABCA transporters in lipid homeostasis.

    Miscellaneous databases

    NextBioi 20869597.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    InterProi IPR003593. AAA+_ATPase.
    IPR013525. ABC_2_trans.
    IPR003439. ABC_transporter-like.
    IPR017871. ABC_transporter_CS.
    IPR020064. ABCG1.
    IPR027417. P-loop_NTPase.
    IPR005284. Pigment_permease.
    [Graphical view ]
    PANTHERi PTHR19241:SF177. PTHR19241:SF177. 1 hit.
    Pfami PF01061. ABC2_membrane. 1 hit.
    PF00005. ABC_tran. 1 hit.
    [Graphical view ]
    SMARTi SM00382. AAA. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00955. 3a01204. 1 hit.
    PROSITEi PS00211. ABC_TRANSPORTER_1. 1 hit.
    PS50893. ABC_TRANSPORTER_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: HerefordImported.
    2. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: HerefordImported.

    Entry informationi

    Entry nameiE1BDU6_BOVIN
    AccessioniPrimary (citable) accession number: E1BDU6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 2, 2010
    Last sequence update: November 2, 2010
    Last modified: October 1, 2014
    This is version 31 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3