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Protein
Submitted name:

HNF1 beta A splice variant 1

Gene

HNF1B

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
HNF1 beta A splice variant 1Imported
Gene namesi
Name:HNF1BImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

  • Nucleus UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

NucleusUniRule annotation

PTM / Processingi

Proteomic databases

PaxDbiE0YMJ6.
PRIDEiE0YMJ6.

Expressioni

Gene expression databases

BgeeiENSG00000108753.
ExpressionAtlasiE0YMJ6. baseline and differential.
GenevisibleiE0YMJ6. HS.

Structurei

3D structure databases

ProteinModelPortaliE0YMJ6.
SMRiE0YMJ6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini203 – 284Homeobox DNA-bindingInterPro annotationAdd BLAST82

Keywords - Domaini

HomeoboxUniRule annotation

Phylogenomic databases

eggNOGiENOG410IFA0. Eukaryota.
ENOG410ZZZ0. LUCA.

Family and domain databases

InterProiView protein in InterPro
IPR006899. HNF-1_N.
IPR023219. HNF1_dimer_dom.
IPR006897. HNF1b_C.
IPR009057. Homeobox-like.
IPR001356. Homeobox_dom.
IPR010982. Lambda_DNA-bd_dom.
PfamiView protein in Pfam
PF04814. HNF-1_N. 1 hit.
PF04812. HNF-1B_C. 1 hit.
PF00046. Homeobox. 1 hit.
SMARTiView protein in SMART
SM00389. HOX. 1 hit.
SUPFAMiSSF100957. SSF100957. 1 hit.
SSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEiView protein in PROSITE
PS50071. HOMEOBOX_2. 1 hit.

Sequencei

Sequence statusi: Complete.

E0YMJ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVSKLTSLQQ ELLSALLSSG VTKEVLVQAL EELLPSPNFG VKLETLPLSP
60 70 80 90 100
GSGAEPDTKP VFHTLTNGHA KGRLSGDEGS EDGDDYDTPP ILKELQALNT
110 120 130 140 150
EEAAEQRAEV DRMLSEDPWR AAKMIKGYMQ QHNIPQREVV DVTGLNQSHL
160 170 180 190 200
SQHLNKGTPM KTQKRAALYT WYVRKQREIL RQFSQQSHGP GQSDDACSEP
210 220 230 240 250
TNKKMRRNRF KWGPASQQIL YQAYDRQKNP SKEEREALVE ECNRAECLQR
260 270 280 290 300
GVSPSKAHGL GSNLVTEVRV YNWFANRRKE EAFRQKLAMD AYSSNQTHSL
310 320 330 340 350
NPLLSHGSPH HQPSSSPPNK LSGVRYSQQG NNEITSSSTI SHHGNSAMVT
360 370 380 390 400
SQSVLQQVSP ASLDPGHNLL SPDGKMISVS GGGLPPVSTL TNIHSLSHHN
410 420 430 440 450
PQQSQNLIMT PLSGVMAIAQ SLNTSQAQSV PVINSVAGSL AALQPVQFSQ
460 470 480 490 500
QLHSPHQQPL MQQSPGSHMA QQPFMAAVTQ LQNSHMYAHK QEPPQYSHTS
510 520 530
RFPSAMVVTD TSSISTLTNM SSSKQCPLQA W
Length:531
Mass (Da):58,379
Last modified:November 2, 2010 - v1
Checksum:iCEC69B827DD176D3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HM116553 mRNA. Translation: ADM43490.1.
RefSeqiNP_001159395.1. NM_001165923.3.
UniGeneiHs.191144.

Genome annotation databases

GeneIDi6928.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiE0YMJ6_HUMAN
AccessioniPrimary (citable) accession number: E0YMJ6
Entry historyiIntegrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 2, 2010
Last modified: July 5, 2017
This is version 46 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.