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Protein
Submitted name:

MHC class I antigen

Gene

HLA-C

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Names & Taxonomyi

Protein namesi
Submitted name:
MHC class I antigenImported
Gene namesi
Name:HLA-CImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PaxDbiE0WMP9.
PeptideAtlasiE0WMP9.
PRIDEiE0WMP9.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini184 – 272Ig-likeInterPro annotationAdd BLAST89

Sequence similaritiesi

Belongs to the MHC class I family.UniRule annotation

Phylogenomic databases

eggNOGiENOG410II5V. Eukaryota.
ENOG4111K8F. LUCA.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
3.30.500.10. 1 hit.
InterProiView protein in InterPro
IPR007110. Ig-like_dom.
IPR036179. Ig-like_dom_sf.
IPR013783. Ig-like_fold.
IPR003597. Ig_C1-set.
IPR011161. MHC_I-like_Ag-recog.
IPR037055. MHC_I-like_Ag-recog_sf.
IPR011162. MHC_I/II-like_Ag-recog.
IPR001039. MHC_I_a_a1/a2.
PfamiView protein in Pfam
PF07654. C1-set. 1 hit.
PF00129. MHC_I. 1 hit.
PRINTSiPR01638. MHCCLASSI.
SMARTiView protein in SMART
SM00407. IGc1. 1 hit.
SUPFAMiSSF48726. SSF48726. 1 hit.
SSF54452. SSF54452. 1 hit.
PROSITEiView protein in PROSITE
PS50835. IG_LIKE. 1 hit.

Sequencei

Sequence statusi: Fragment.

E0WMP9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
SHSMRYFDTA VSRPGRGEPR FISVGYVDDT QFVRFDSDAA SPRGEPRAPW
60 70 80 90 100
VEQEGPEYWD RETQKYKRQA QADRVSLRNL RGYYNQSEDG SHTLQRMSGC
110 120 130 140 150
DLGPDGRLLR GYDQSAYDGK DYIALNEDLR SWTAADTAAQ ITQRKLEAAR
160 170 180 190 200
AAEQLRTYLE GTCVEWLRRY LENGKETLQR AEPPKTHVTH HPLSDHEATL
210 220 230 240 250
RCWALGFYPA EITLTWQRDG EDQTQDTELV ETRPAGDGTF QKWAAVVVPS
260 270
GQEQRYTCHM QHEGLQEPLT LSWGK
Length:275
Mass (Da):31,546
Last modified:November 2, 2010 - v1
Checksum:i2A862545B633A32A
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei275Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FR686493 Genomic DNA. Translation: CBW47559.1.
UniGeneiHs.656020.
Hs.743218.

Similar proteinsi

Entry informationi

Entry nameiE0WMP9_HUMAN
AccessioniPrimary (citable) accession number: E0WMP9
Entry historyiIntegrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 2, 2010
Last modified: October 25, 2017
This is version 36 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.