E0W2H3 (E0W2H3_PEDHC) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
DNA ligase, putative EMBL EEB19829.1
EC=6.5.1.1 EMBL EEB19829.1

Gene names

ORF Names:

Phum_PHUM592850 EMBL EEB19829.1

Organism

Pediculus humanus subsp. corporis (Body louse) [Reference proteome]

Taxonomic identifier

121224 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Paraneoptera › Phthiraptera › Anoplura › Pediculidae › Pediculus › Pediculus humanus

Protein attributes

Sequence length	891 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the ATP-dependent DNA ligase family. RuleBase RU004196

Ontologies

Keywords
Molecular function	Ligase EMBL EEB19829.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	DNA ligation involved in DNA repair Inferred from electronic annotation. Source: InterPro DNA recombination Inferred from electronic annotation. Source: InterPro DNA replication Inferred from electronic annotation. Source: InterPro
Molecular_function	ATP binding Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA ligase (ATP) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E0W2H3 [UniParc]. Last modified November 2, 2010. Version 1. Checksum: E252DFE0E852D929	FASTA	891	102,161
	10 20 30 40 50 60 MSLAKKISFG NFCQLCSKIK SADHEKKIII LRNYISNWKK KAKDIESDGL NLDDSFFPIF 70 80 90 100 110 120 RLLIPHLDRE RGAYGIKERT LAKIYISILS LPKDGEDALK LLNCKNPKTS YFNNCDFASI 130 140 150 160 170 180 AFCILRNRCA EGGQLSVEEV NKHLDKISTS HAANEPRNVD AELISLLKST NAEEQKWLIR 190 200 210 220 230 240 ILLKDVKLGL SENVIFKCYH PDARELYDSS NSLRKICDLL NDPEIRLNEI QIQLFTPFKP 250 260 270 280 290 300 MLSEECDIQK IDYYLKRSCH FFIETKLDGE RFQLHFEEGN FKYFSRNGYD FTTNFGSSKR 310 320 330 340 350 360 EGNLSPRIFK RIPPHVKSFV LDGEMMSWDR ITRSFSSKGK NLDVKNLKEG NHYQSCFCVF 370 380 390 400 410 420 DILLYNGEVL TNKPLIARLE ILEKIIEPEE GTIIILNRKQ ISSNSEVIDS LNEAIDNREE 430 440 450 460 470 480 GIVMKESMSV YKPNVRKNGG WYKIKPEYTD GLAETLDLLI IGGYYGRGHL KGSVNHFLLG 490 500 510 520 530 540 AAVNVSDDNI LFYSTGRVGS GYSIKDLEDL SLKLKPYWKE AKNDRMPLSV KWGKEKPDVW 550 560 570 580 590 600 IKPDKSYILE IKASEIVSSA IFKSGYALRF PRVEKIRYDK TWKECLTLHN LEEIAKIASG 610 620 630 640 650 660 KLTASHFSQS NIPSFLPKKK AKTSIWNINS ENFDFSGIKC ISKLLQGKEI CVFSGFKNIK 670 680 690 700 710 720 KLDLEKKVVE FGGKLVKNPG KNTFCILAES DNHTRIKNII KCGSYDILYS SCFFSFLKIE 730 740 750 760 770 780 NVKMPKLKPE HFLAMSKGTK EEFSKSYDKY GDHFTKKSTF DAIKHSLNAA SQEGKNIVLT 790 800 810 820 830 840 SDEIYEMDVN LFGKTSPYSI FRNHVGYFDQ FKIVSDSSSK FSSDLDLFKI DFRFYGGKCS 850 860 870 880 890 DAIDDSTVTH VITLSSDSSR INEINNENHK RKRKFHVVNE KWIESCIKEN A

References

[1]

"Genome sequences of the human body louse and its primary endosymbiont provide insights into the permanent parasitic lifestyle." Kirkness E.F., Haas B.J., Sun W., Braig H.R., Perotti M.A., Clark J.M., Lee S.H., Robertson H.M., Kennedy R.C., Elhaik E., Gerlach D., Kriventseva E.V., Elsik C.G., Graur D., Hill C.A., Veenstra J.A., Walenz B., Tubio J.M. , Ribeiro J.M., Rozas J., Johnston J.S., Reese J.T., Popadic A., Tojo M., Raoult D., Reed D.L., Tomoyasu Y., Krause E., Mittapalli O., Margam V.M., Li H.M., Meyer J.M., Johnson R.M., Romero-Severson J., Vanzee J.P., Alvarez-Ponce D., Vieira F.G., Aguade M., Guirao-Rico S., Anzola J.M., Yoon K.S., Strycharz J.P., Unger M.F., Christley S., Lobo N.F., Seufferheld M.J., Wang N., Dasch G.A., Struchiner C.J., Madey G., Hannick L.I., Bidwell S., Joardar V., Caler E., Shao R., Barker S.C., Cameron S., Bruggner R.V., Regier A., Johnson J., Viswanathan L., Utterback T.R., Sutton G.G., Lawson D., Waterhouse R.M., Venter J.C., Strausberg R.L., Berenbaum M.R., Collins F.H., Zdobnov E.M., Pittendrigh B.R. Proc. Natl. Acad. Sci. U.S.A. 107:12168-12173(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: USDA.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DS235878 Genomic DNA. Translation: EEB19829.1.
RefSeq	XP_002432567.1. XM_002432522.1.
3D structure databases
ProteinModelPortal	E0W2H3.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	8232803.
KEGG	phu:Phum_PHUM592850.
VectorBase	PHUM592850. Pediculus humanus.
Organism-specific databases
CTD	8232803.
Phylogenomic databases
KO	K10777.
OMA	ISHFLCA.
Family and domain databases
Gene3D	1.10.3260.10. 1 hit. 2.40.50.140. 1 hit.
InterPro	IPR001357. BRCT_dom. IPR000977. DNA_ligase_ATP-dep. IPR012309. DNA_ligase_ATP-dep_C. IPR012310. DNA_ligase_ATP-dep_cent. IPR016059. DNA_ligase_ATP-dep_CS. IPR012308. DNA_ligase_ATP-dep_N. IPR012340. NA-bd_OB-fold. [Graphical view]
Pfam	PF00533. BRCT. 1 hit. PF04679. DNA_ligase_A_C. 1 hit. PF01068. DNA_ligase_A_M. 1 hit. PF04675. DNA_ligase_A_N. 1 hit. [Graphical view]
SMART	SM00292. BRCT. 2 hits. [Graphical view]
SUPFAM	SSF52113. BRCT. 2 hits. SSF50249. Nucleic_acid_OB. 1 hit.
TIGRFAMs	TIGR00574. dnl1. 1 hit.
PROSITE	PS50172. BRCT. 1 hit. PS00333. DNA_LIGASE_A2. 1 hit. PS50160. DNA_LIGASE_A3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

E0W2H3_PEDHC

Accession

Primary (citable) accession number: E0W2H3

Entry history

Integrated into UniProtKB/TrEMBL:	November 2, 2010
Last sequence update:	November 2, 2010
Last modified:	March 6, 2013
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)