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E0W2H3

- E0W2H3_PEDHC

UniProt

E0W2H3 - E0W2H3_PEDHC

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Protein
Submitted name: DNA ligase, putative
Gene
Phum_PHUM592850
Organism
Pediculus humanus subsp. corporis (Body louse)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. DNA ligation involved in DNA repair Source: InterPro
  2. DNA recombination Source: InterPro
  3. DNA replication Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LigaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
DNA ligase, putativeImported (EC:6.5.1.1Imported)
Gene namesi
ORF Names:Phum_PHUM592850Imported
OrganismiPediculus humanus subsp. corporis (Body louse)
Taxonomic identifieri121224 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraParaneopteraPhthirapteraAnopluraPediculidaePediculus
ProteomesiUP000009046: Partially assembled WGS sequence

Structurei

3D structure databases

ProteinModelPortaliE0W2H3.

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

KOiK10777.
OMAiISHFLCA.
OrthoDBiEOG7BKCT2.
PhylomeDBiE0W2H3.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
3.40.50.10190. 1 hit.
InterProiIPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF00533. BRCT. 1 hit.
PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SMARTiSM00292. BRCT. 2 hits.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 2 hits.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS50172. BRCT. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E0W2H3-1 [UniParc]FASTAAdd to Basket

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MSLAKKISFG NFCQLCSKIK SADHEKKIII LRNYISNWKK KAKDIESDGL    50
NLDDSFFPIF RLLIPHLDRE RGAYGIKERT LAKIYISILS LPKDGEDALK 100
LLNCKNPKTS YFNNCDFASI AFCILRNRCA EGGQLSVEEV NKHLDKISTS 150
HAANEPRNVD AELISLLKST NAEEQKWLIR ILLKDVKLGL SENVIFKCYH 200
PDARELYDSS NSLRKICDLL NDPEIRLNEI QIQLFTPFKP MLSEECDIQK 250
IDYYLKRSCH FFIETKLDGE RFQLHFEEGN FKYFSRNGYD FTTNFGSSKR 300
EGNLSPRIFK RIPPHVKSFV LDGEMMSWDR ITRSFSSKGK NLDVKNLKEG 350
NHYQSCFCVF DILLYNGEVL TNKPLIARLE ILEKIIEPEE GTIIILNRKQ 400
ISSNSEVIDS LNEAIDNREE GIVMKESMSV YKPNVRKNGG WYKIKPEYTD 450
GLAETLDLLI IGGYYGRGHL KGSVNHFLLG AAVNVSDDNI LFYSTGRVGS 500
GYSIKDLEDL SLKLKPYWKE AKNDRMPLSV KWGKEKPDVW IKPDKSYILE 550
IKASEIVSSA IFKSGYALRF PRVEKIRYDK TWKECLTLHN LEEIAKIASG 600
KLTASHFSQS NIPSFLPKKK AKTSIWNINS ENFDFSGIKC ISKLLQGKEI 650
CVFSGFKNIK KLDLEKKVVE FGGKLVKNPG KNTFCILAES DNHTRIKNII 700
KCGSYDILYS SCFFSFLKIE NVKMPKLKPE HFLAMSKGTK EEFSKSYDKY 750
GDHFTKKSTF DAIKHSLNAA SQEGKNIVLT SDEIYEMDVN LFGKTSPYSI 800
FRNHVGYFDQ FKIVSDSSSK FSSDLDLFKI DFRFYGGKCS DAIDDSTVTH 850
VITLSSDSSR INEINNENHK RKRKFHVVNE KWIESCIKEN A 891
Length:891
Mass (Da):102,161
Last modified:November 2, 2010 - v1
Checksum:iE252DFE0E852D929
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS235878 Genomic DNA. Translation: EEB19829.1.
RefSeqiXP_002432567.1. XM_002432522.1.

Genome annotation databases

GeneIDi8232803.
KEGGiphu:Phum_PHUM592850.
VectorBaseiPHUM592850. Pediculus humanus.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS235878 Genomic DNA. Translation: EEB19829.1 .
RefSeqi XP_002432567.1. XM_002432522.1.

3D structure databases

ProteinModelPortali E0W2H3.
ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 8232803.
KEGGi phu:Phum_PHUM592850.
VectorBasei PHUM592850. Pediculus humanus.

Organism-specific databases

CTDi 8232803.

Phylogenomic databases

KOi K10777.
OMAi ISHFLCA.
OrthoDBi EOG7BKCT2.
PhylomeDBi E0W2H3.

Family and domain databases

Gene3Di 1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
3.40.50.10190. 1 hit.
InterProi IPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
Pfami PF00533. BRCT. 1 hit.
PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view ]
SMARTi SM00292. BRCT. 2 hits.
[Graphical view ]
SUPFAMi SSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 2 hits.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS50172. BRCT. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequences of the human body louse and its primary endosymbiont provide insights into the permanent parasitic lifestyle."
    Kirkness E.F., Haas B.J., Sun W., Braig H.R., Perotti M.A., Clark J.M., Lee S.H., Robertson H.M., Kennedy R.C., Elhaik E., Gerlach D., Kriventseva E.V., Elsik C.G., Graur D., Hill C.A., Veenstra J.A., Walenz B., Tubio J.M.
    , Ribeiro J.M., Rozas J., Johnston J.S., Reese J.T., Popadic A., Tojo M., Raoult D., Reed D.L., Tomoyasu Y., Krause E., Mittapalli O., Margam V.M., Li H.M., Meyer J.M., Johnson R.M., Romero-Severson J., Vanzee J.P., Alvarez-Ponce D., Vieira F.G., Aguade M., Guirao-Rico S., Anzola J.M., Yoon K.S., Strycharz J.P., Unger M.F., Christley S., Lobo N.F., Seufferheld M.J., Wang N., Dasch G.A., Struchiner C.J., Madey G., Hannick L.I., Bidwell S., Joardar V., Caler E., Shao R., Barker S.C., Cameron S., Bruggner R.V., Regier A., Johnson J., Viswanathan L., Utterback T.R., Sutton G.G., Lawson D., Waterhouse R.M., Venter J.C., Strausberg R.L., Berenbaum M.R., Collins F.H., Zdobnov E.M., Pittendrigh B.R.
    Proc. Natl. Acad. Sci. U.S.A. 107:12168-12173(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: USDA.

Entry informationi

Entry nameiE0W2H3_PEDHC
AccessioniPrimary (citable) accession number: E0W2H3
Entry historyi
Integrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 2, 2010
Last modified: June 11, 2014
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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