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Protein
Submitted name:

Histone-lysine N-methyltransferase SUVR5, putative

Gene

Phum_PHUM463920

Organism
Pediculus humanus subsp. corporis (Body louse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].SAAS annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotationSAAS annotationImported, Transferase

Keywords - Ligandi

S-adenosyl-L-methionineSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Histone-lysine N-methyltransferase SUVR5, putativeImported (EC:2.1.1.43Imported)
Gene namesi
ORF Names:Phum_PHUM463920Imported
OrganismiPediculus humanus subsp. corporis (Body louse)Imported
Taxonomic identifieri121224 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraParaneopteraPhthirapteraAnopluraPediculidaePediculus
Proteomesi
  • UP000009046 Componenti: Partially assembled WGS sequence

Subcellular locationi

  • Nucleus SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini507 – 560AWSInterPro annotationAdd BLAST54
Domaini562 – 679SETInterPro annotationAdd BLAST118
Domaini686 – 702Post-SETInterPro annotationAdd BLAST17
Domaini1274 – 1307WWInterPro annotationAdd BLAST34

Sequence similaritiesi

Belongs to the class V-like SAM-binding methyltransferase superfamily.SAAS annotation
Contains 1 SET domain.UniRule annotation
Contains 1 post-SET domain.UniRule annotation

Phylogenomic databases

InParanoidiE0VVJ9.
KOiK11423.
OMAiVRRMVCD.
PhylomeDBiE0VVJ9.

Family and domain databases

InterProiIPR006560. AWS_dom.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
IPR013257. SRI.
IPR001202. WW_dom.
[Graphical view]
PfamiPF00856. SET. 1 hit.
PF08236. SRI. 1 hit.
PF00397. WW. 1 hit.
[Graphical view]
SMARTiSM00570. AWS. 1 hit.
SM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
SM00456. WW. 1 hit.
[Graphical view]
SUPFAMiSSF51045. SSF51045. 1 hit.
PROSITEiPS51215. AWS. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
PS01159. WW_DOMAIN_1. 1 hit.
PS50020. WW_DOMAIN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E0VVJ9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARRRRGASI KSARQSRKIK KNEKVNGLLP SNKSILDDSS HLIESETGNS
60 70 80 90 100
LNDASICISS NCFETSSDPV VHHKKFGKIR VSGQNENSLD VEPLMTEANK
110 120 130 140 150
DYNRFDSKSS DENECDNVEN NTFSNDVSVL DIMRGIEITG AKAQNSFVDF
160 170 180 190 200
RKQSSVYKAE NDIPLDGSVI IKPGTFSSNT ITSSVKPNLF FDTATTSEIN
210 220 230 240 250
SVNFLKVLQG IEMLERNVSG SSVPLEFGES LPKQEKDFLN TSTSSTPVYF
260 270 280 290 300
NEESGSKILY ADDELPGNCV KSETEELNNV IMNVVENSKI EDSIKKNISS
310 320 330 340 350
PEDTSSDIQN ETEETTRKLQ SIGLDEQWER YESPASKASD ETSDKKAPAA
360 370 380 390 400
KSRTGSTDVA ETDSNSNLGG TIRRSNRIRS IGIMKQKERE QAAVKSENVL
410 420 430 440 450
KSPMASGSPA VTPPVPAYDD KPVKVKSRWR RSSELEMHCG KVDSESVSST
460 470 480 490 500
CSSPVSLPFQ MSCNAEPSPE DLEKLEREKK EIEEGLKSFT VLTENEYKME
510 520 530 540 550
RSACKETKRM ICDCVLTKEE LNRGEVGCGE DCLNRMLFLE CGSRCALGDR
560 570 580 590 600
CTNKRFQKLQ YANCKIFKTE KKGFGLRAEE DLSGNTFIME YVGEVVNQKE
610 620 630 640 650
FGRRVKMYAK ENNKHFYFMA LKGDAVIDAT NKGNISRFIN HSCDPNAETQ
660 670 680 690 700
KWTINGELRV GFFTRRFVAA GEEITFDYQF QRYGKQAQKC YCEASNCRGW
710 720 730 740 750
IGENPDESFE DDEEGEEDDD EDEDIDEEEE EYEEEGEDKK LSRKMGKIDD
760 770 780 790 800
DKDKKEDSGK IVPSVQKVKR QRKLSERKKK DRKTTTIVDD MGLDEEIQKL
810 820 830 840 850
FQTGLKNRAH TLTLSRLMVR AEDWSTRGKL LKLIREGETP CRRLFLDYHG
860 870 880 890 900
LRLICSWMLS RELEESNDKN DRRLEILKTL SKLPIPNKNM LIDSKVLTVV
910 920 930 940 950
EQWAKSGFLT RKLSVDDETV NDERKLKPEP ESIPGLGGEI VDKTTQNVLN
960 970 980 990 1000
GENFDKPDGS EEVNESAEKV KRMADIVLES WSSLKEVFKI PKKERIEQMK
1010 1020 1030 1040 1050
EHERQADRGY CEYLGKENVR DKYDRHDRYG RYRDRERERM RDRKRTRESP
1060 1070 1080 1090 1100
PDPEWFRNHE RKMKMTKHER RQLFALKVLQ EDEEAKKRNE HLEMWKQHES
1110 1120 1130 1140 1150
RCLALGLDPN LNAACDPQTG FPIFFDHNSG TWQNCPSSSG PSPSVPHSVT
1160 1170 1180 1190 1200
PTICPSPMYS VNSALIQNCP MCTNIPVCSN VNNPICHNGM VHTNMPLTNG
1210 1220 1230 1240 1250
PVCSNITVSP CQRQNYSNMT TQYQGQLPQS NLEVLDATYH ESVSSLNAQQ
1260 1270 1280 1290 1300
SFDESSSNEL NRPLITETPL NFPIKLPPKW KAAKDPKGRV YYYHIKERVS
1310 1320 1330 1340 1350
QWEPPQWSEE EAKIEAAKTV DLEMGEESSS STESSTDREK VTASSDTATD
1360 1370 1380 1390 1400
KKIKENFKNN MAGAIVSHLN PYRKQDCKIG RITCNEDFKH LARKLTHFVM
1410 1420 1430 1440
LKELKHCKGV DDLECNDSVK AKAKDFIKKY MAKFGAVYQR PKHEVWKT
Length:1,448
Mass (Da):164,897
Last modified:November 2, 2010 - v1
Checksum:iB99AB59B9F483CF4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS235812 Genomic DNA. Translation: EEB17405.1.
RefSeqiXP_002430143.1. XM_002430098.1.

Genome annotation databases

EnsemblMetazoaiPHUM463920-RA; PHUM463920-PA; PHUM463920.
GeneIDi8238587.
KEGGiphu:Phum_PHUM463920.
VectorBaseiPHUM463920-RA; PHUM463920-PA; PHUM463920.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS235812 Genomic DNA. Translation: EEB17405.1.
RefSeqiXP_002430143.1. XM_002430098.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiPHUM463920-RA; PHUM463920-PA; PHUM463920.
GeneIDi8238587.
KEGGiphu:Phum_PHUM463920.
VectorBaseiPHUM463920-RA; PHUM463920-PA; PHUM463920.

Organism-specific databases

CTDi8238587.

Phylogenomic databases

InParanoidiE0VVJ9.
KOiK11423.
OMAiVRRMVCD.
PhylomeDBiE0VVJ9.

Family and domain databases

InterProiIPR006560. AWS_dom.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
IPR013257. SRI.
IPR001202. WW_dom.
[Graphical view]
PfamiPF00856. SET. 1 hit.
PF08236. SRI. 1 hit.
PF00397. WW. 1 hit.
[Graphical view]
SMARTiSM00570. AWS. 1 hit.
SM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
SM00456. WW. 1 hit.
[Graphical view]
SUPFAMiSSF51045. SSF51045. 1 hit.
PROSITEiPS51215. AWS. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
PS01159. WW_DOMAIN_1. 1 hit.
PS50020. WW_DOMAIN_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiE0VVJ9_PEDHC
AccessioniPrimary (citable) accession number: E0VVJ9
Entry historyi
Integrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 2, 2010
Last modified: November 30, 2016
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.