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E0VU28

- E0VU28_PEDHC

UniProt

E0VU28 - E0VU28_PEDHC

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Protein
Submitted name:

Hemocyte protein-glutamine gamma-glutamyltransferase, putative

Gene

Phum_PHUM442960

Organism
Pediculus humanus subsp. corporis (Body louse)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

Cofactori

Binds 1 calcium ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei336 – 3361UniRule annotation
Active sitei399 – 3991UniRule annotation
Active sitei422 – 4221UniRule annotation
Metal bindingi462 – 4621Calcium
Metal bindingi464 – 4641Calcium
Metal bindingi521 – 5211Calcium
Metal bindingi526 – 5261Calcium

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein-glutamine gamma-glutamyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. peptide cross-linking Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

AcyltransferaseImported, Transferase

Keywords - Ligandi

CalciumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Hemocyte protein-glutamine gamma-glutamyltransferase, putativeImported (EC:2.3.2.13Imported)
Gene namesi
ORF Names:Phum_PHUM442960Imported
OrganismiPediculus humanus subsp. corporis (Body louse)Imported
Taxonomic identifieri121224 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraParaneopteraPhthirapteraAnopluraPediculidaePediculus
ProteomesiUP000009046: Partially assembled WGS sequence

Family & Domainsi

Phylogenomic databases

InParanoidiE0VU28.
KOiK05619.
OMAiHEINGDI.
OrthoDBiEOG7B8S3J.
PhylomeDBiE0VU28.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.

Sequencei

Sequence statusi: Complete.

E0VU28-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSLRNDMGFY NGRSNNQNRN PEITNYMSNL MKKFNKDYER RRKQDENFSH
60 70 80 90 100
HFMGSPEFNI LTTMDVEFYA IENSKTHHTD KFELVQQDPK IPILRRGQHF
110 120 130 140 150
FIAVKFNRKI NFENDVIRLI FIFGPKPSVN KGTRAIVQVV KKDELNEDKW
160 170 180 190 200
DAAVHEINGD IVSIKVNIPV VSPVGLWNLN IQTSSTDVTS SFKNYKCKKD
210 220 230 240 250
IYVLFNPWCK DDEVYLEDEN ERNEYVLNDT GKIWMGSYLK PKGRRWFYGQ
260 270 280 290 300
FDDVVLPAVV HLLEKSKLKH GERGNVIQMA RAISAVVNSE DEDGLIEGKW
310 320 330 340 350
VGDFAGGTSP FAWTGSVAIM ENYLKSNGKS VKYGQCWVFS GAAVTICRAL
360 370 380 390 400
GIPARPVTNY ASAHDTNSSL TLDKYFTRDG TEIEGGPDGD CYDSCWNFHV
410 420 430 440 450
WVDVWMKRPD LPPSFSGWQI IDSTPQELSD NAYKCGPAPI EAVRRGEIGY
460 470 480 490 500
LYDTPFAFAA VNADILHFQE DDESPWGFSR LNFDDCHVGK KLVTKKVGVD
510 520 530 540 550
DDDEDSVNDM EDVTNLYKNP EGSTSERLAV LTAIRKSRKA RIQYDIALPH
560 570 580 590 600
EEDVVFRLDE IDTIDYGQSF RVIVRIENNS EEPRTIQATM AANSVFYTGV
610 620 630 640 650
SAYDLKKASG TMHLKGRTTE IMHITITPEE YLDKLVDHSL VKIFSIATVK
660 670 680 690 700
ETKQNWSKED YFSFTKPSID ITVSGHLKVG YPVTAYFTFK NPIYRRLTDC
710 720 730 740 750
TVSFEGPGLQ RPKLVNFADV EPNDDVHFTE TFVPKKSGPR KIMALFNSKL
760
LNNVTAPVIK
Length:760
Mass (Da):86,586
Last modified:November 2, 2010 - v1
Checksum:i5C1F17C3A53A0FBF
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS235778 Genomic DNA. Translation: EEB16884.1.
RefSeqiXP_002429622.1. XM_002429577.1.

Genome annotation databases

EnsemblMetazoaiPHUM442960-RA; PHUM442960-PA; PHUM442960.
GeneIDi8230915.
KEGGiphu:Phum_PHUM442960.
VectorBaseiPHUM442960. Pediculus humanus.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS235778 Genomic DNA. Translation: EEB16884.1 .
RefSeqi XP_002429622.1. XM_002429577.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai PHUM442960-RA ; PHUM442960-PA ; PHUM442960 .
GeneIDi 8230915.
KEGGi phu:Phum_PHUM442960.
VectorBasei PHUM442960. Pediculus humanus.

Organism-specific databases

CTDi 8230915.

Phylogenomic databases

InParanoidi E0VU28.
KOi K05619.
OMAi HEINGDI.
OrthoDBi EOG7B8S3J.
PhylomeDBi E0VU28.

Family and domain databases

Gene3Di 2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProi IPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR001102. Transglutaminase_N.
[Graphical view ]
PANTHERi PTHR11590. PTHR11590. 1 hit.
Pfami PF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000459. TGM_EBP42. 1 hit.
SMARTi SM00460. TGc. 1 hit.
[Graphical view ]
SUPFAMi SSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Genome sequences of the human body louse and its primary endosymbiont provide insights into the permanent parasitic lifestyle."
    Kirkness E.F., Haas B.J., Sun W., Braig H.R., Perotti M.A., Clark J.M., Lee S.H., Robertson H.M., Kennedy R.C., Elhaik E., Gerlach D., Kriventseva E.V., Elsik C.G., Graur D., Hill C.A., Veenstra J.A., Walenz B., Tubio J.M.
    , Ribeiro J.M., Rozas J., Johnston J.S., Reese J.T., Popadic A., Tojo M., Raoult D., Reed D.L., Tomoyasu Y., Krause E., Mittapalli O., Margam V.M., Li H.M., Meyer J.M., Johnson R.M., Romero-Severson J., Vanzee J.P., Alvarez-Ponce D., Vieira F.G., Aguade M., Guirao-Rico S., Anzola J.M., Yoon K.S., Strycharz J.P., Unger M.F., Christley S., Lobo N.F., Seufferheld M.J., Wang N., Dasch G.A., Struchiner C.J., Madey G., Hannick L.I., Bidwell S., Joardar V., Caler E., Shao R., Barker S.C., Cameron S., Bruggner R.V., Regier A., Johnson J., Viswanathan L., Utterback T.R., Sutton G.G., Lawson D., Waterhouse R.M., Venter J.C., Strausberg R.L., Berenbaum M.R., Collins F.H., Zdobnov E.M., Pittendrigh B.R.
    Proc. Natl. Acad. Sci. U.S.A. 107:12168-12173(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: USDAImported.

Entry informationi

Entry nameiE0VU28_PEDHC
AccessioniPrimary (citable) accession number: E0VU28
Entry historyi
Integrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 2, 2010
Last modified: October 29, 2014
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3