E0VU28 (E0VU28_PEDHC) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Hemocyte protein-glutamine gamma-glutamyltransferase, putative EMBL EEB16884.1
EC=2.3.2.13 EMBL EEB16884.1

Gene names

ORF Names:

Phum_PHUM442960 EMBL EEB16884.1

Organism

Pediculus humanus subsp. corporis (Body louse) [Reference proteome]

Taxonomic identifier

121224 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Paraneoptera › Phthiraptera › Anoplura › Pediculidae › Pediculus › Pediculus humanus

Protein attributes

Sequence length	760 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor

Binds 1 calcium ion per subunit By similarity. PIRSR PIRSR000459-2

Ontologies

Keywords
Ligand	Calcium PIRSR PIRSR000459-2 Metal-binding PIRSR PIRSR000459-2
Molecular function	Acyltransferase EMBL EEB16884.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	peptide cross-linking Inferred from electronic annotation. Source: InterPro
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW protein-glutamine gamma-glutamyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	336	1	By similarity PIRSR PIRSR000459-1
	Active site	399	1	By similarity PIRSR PIRSR000459-1
	Active site	422	1	By similarity PIRSR PIRSR000459-1
	Metal binding	462	1	Calcium By similarity PIRSR PIRSR000459-2
	Metal binding	464	1	Calcium By similarity PIRSR PIRSR000459-2
	Metal binding	521	1	Calcium By similarity PIRSR PIRSR000459-2
	Metal binding	526	1	Calcium By similarity PIRSR PIRSR000459-2

Sequences

	Sequence		Length	Mass (Da)
	E0VU28 [UniParc]. Last modified November 2, 2010. Version 1. Checksum: 5C1F17C3A53A0FBF	FASTA	760	86,586
	10 20 30 40 50 60 MSLRNDMGFY NGRSNNQNRN PEITNYMSNL MKKFNKDYER RRKQDENFSH HFMGSPEFNI 70 80 90 100 110 120 LTTMDVEFYA IENSKTHHTD KFELVQQDPK IPILRRGQHF FIAVKFNRKI NFENDVIRLI 130 140 150 160 170 180 FIFGPKPSVN KGTRAIVQVV KKDELNEDKW DAAVHEINGD IVSIKVNIPV VSPVGLWNLN 190 200 210 220 230 240 IQTSSTDVTS SFKNYKCKKD IYVLFNPWCK DDEVYLEDEN ERNEYVLNDT GKIWMGSYLK 250 260 270 280 290 300 PKGRRWFYGQ FDDVVLPAVV HLLEKSKLKH GERGNVIQMA RAISAVVNSE DEDGLIEGKW 310 320 330 340 350 360 VGDFAGGTSP FAWTGSVAIM ENYLKSNGKS VKYGQCWVFS GAAVTICRAL GIPARPVTNY 370 380 390 400 410 420 ASAHDTNSSL TLDKYFTRDG TEIEGGPDGD CYDSCWNFHV WVDVWMKRPD LPPSFSGWQI 430 440 450 460 470 480 IDSTPQELSD NAYKCGPAPI EAVRRGEIGY LYDTPFAFAA VNADILHFQE DDESPWGFSR 490 500 510 520 530 540 LNFDDCHVGK KLVTKKVGVD DDDEDSVNDM EDVTNLYKNP EGSTSERLAV LTAIRKSRKA 550 560 570 580 590 600 RIQYDIALPH EEDVVFRLDE IDTIDYGQSF RVIVRIENNS EEPRTIQATM AANSVFYTGV 610 620 630 640 650 660 SAYDLKKASG TMHLKGRTTE IMHITITPEE YLDKLVDHSL VKIFSIATVK ETKQNWSKED 670 680 690 700 710 720 YFSFTKPSID ITVSGHLKVG YPVTAYFTFK NPIYRRLTDC TVSFEGPGLQ RPKLVNFADV 730 740 750 760 EPNDDVHFTE TFVPKKSGPR KIMALFNSKL LNNVTAPVIK

References

[1]

"Genome sequences of the human body louse and its primary endosymbiont provide insights into the permanent parasitic lifestyle." Kirkness E.F., Haas B.J., Sun W., Braig H.R., Perotti M.A., Clark J.M., Lee S.H., Robertson H.M., Kennedy R.C., Elhaik E., Gerlach D., Kriventseva E.V., Elsik C.G., Graur D., Hill C.A., Veenstra J.A., Walenz B., Tubio J.M. , Ribeiro J.M., Rozas J., Johnston J.S., Reese J.T., Popadic A., Tojo M., Raoult D., Reed D.L., Tomoyasu Y., Krause E., Mittapalli O., Margam V.M., Li H.M., Meyer J.M., Johnson R.M., Romero-Severson J., Vanzee J.P., Alvarez-Ponce D., Vieira F.G., Aguade M., Guirao-Rico S., Anzola J.M., Yoon K.S., Strycharz J.P., Unger M.F., Christley S., Lobo N.F., Seufferheld M.J., Wang N., Dasch G.A., Struchiner C.J., Madey G., Hannick L.I., Bidwell S., Joardar V., Caler E., Shao R., Barker S.C., Cameron S., Bruggner R.V., Regier A., Johnson J., Viswanathan L., Utterback T.R., Sutton G.G., Lawson D., Waterhouse R.M., Venter J.C., Strausberg R.L., Berenbaum M.R., Collins F.H., Zdobnov E.M., Pittendrigh B.R. Proc. Natl. Acad. Sci. U.S.A. 107:12168-12173(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: USDA.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DS235778 Genomic DNA. Translation: EEB16884.1.
RefSeq	XP_002429622.1. XM_002429577.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	8230915.
KEGG	phu:Phum_PHUM442960.
VectorBase	PHUM442960. Pediculus humanus.
Organism-specific databases
CTD	8230915.
Phylogenomic databases
KO	K05619.
OMA	WQIIDST.
Family and domain databases
Gene3D	2.60.40.10. 3 hits.
InterPro	IPR023608. Gln_gamma-glutamylTfrase_euk. IPR013783. Ig-like_fold. IPR014756. Ig_E-set. IPR002931. Transglutaminase-like. IPR008958. Transglutaminase_C. IPR001102. Transglutaminase_N. [Graphical view]
PANTHER	PTHR11590. PTHR11590. 1 hit.
Pfam	PF00927. Transglut_C. 2 hits. PF01841. Transglut_core. 1 hit. PF00868. Transglut_N. 1 hit. [Graphical view]
PIRSF	PIRSF000459. TGM_EBP42. 1 hit.
SMART	SM00460. TGc. 1 hit. [Graphical view]
SUPFAM	SSF81296. Ig_E-set. 1 hit. SSF49309. Transglut_C. 2 hits.
ProtoNet	Search...

Entry information

Entry name

E0VU28_PEDHC

Accession

Primary (citable) accession number: E0VU28

Entry history

Integrated into UniProtKB/TrEMBL:	November 2, 2010
Last sequence update:	November 2, 2010
Last modified:	April 3, 2013
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)