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Protein
Submitted name:

Hemocyte protein-glutamine gamma-glutamyltransferase, putative

Gene

Phum_PHUM442960

Organism
Pediculus humanus subsp. corporis (Body louse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Cofactori

Note: Binds 1 calcium ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei336 – 3361UniRule annotation
Active sitei399 – 3991UniRule annotation
Active sitei422 – 4221UniRule annotation

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein-glutamine gamma-glutamyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. peptide cross-linking Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

AcyltransferaseImported, Transferase

Keywords - Ligandi

CalciumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Hemocyte protein-glutamine gamma-glutamyltransferase, putativeImported (EC:2.3.2.13Imported)
Gene namesi
ORF Names:Phum_PHUM442960Imported
OrganismiPediculus humanus subsp. corporis (Body louse)Imported
Taxonomic identifieri121224 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraParaneopteraPhthirapteraAnopluraPediculidaePediculus
ProteomesiUP000009046 Componenti: Partially assembled WGS sequence

Family & Domainsi

Phylogenomic databases

InParanoidiE0VU28.
KOiK05619.
OMAiHEINGDI.
OrthoDBiEOG7B8S3J.
PhylomeDBiE0VU28.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.

Sequencei

Sequence statusi: Complete.

E0VU28-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLRNDMGFY NGRSNNQNRN PEITNYMSNL MKKFNKDYER RRKQDENFSH
60 70 80 90 100
HFMGSPEFNI LTTMDVEFYA IENSKTHHTD KFELVQQDPK IPILRRGQHF
110 120 130 140 150
FIAVKFNRKI NFENDVIRLI FIFGPKPSVN KGTRAIVQVV KKDELNEDKW
160 170 180 190 200
DAAVHEINGD IVSIKVNIPV VSPVGLWNLN IQTSSTDVTS SFKNYKCKKD
210 220 230 240 250
IYVLFNPWCK DDEVYLEDEN ERNEYVLNDT GKIWMGSYLK PKGRRWFYGQ
260 270 280 290 300
FDDVVLPAVV HLLEKSKLKH GERGNVIQMA RAISAVVNSE DEDGLIEGKW
310 320 330 340 350
VGDFAGGTSP FAWTGSVAIM ENYLKSNGKS VKYGQCWVFS GAAVTICRAL
360 370 380 390 400
GIPARPVTNY ASAHDTNSSL TLDKYFTRDG TEIEGGPDGD CYDSCWNFHV
410 420 430 440 450
WVDVWMKRPD LPPSFSGWQI IDSTPQELSD NAYKCGPAPI EAVRRGEIGY
460 470 480 490 500
LYDTPFAFAA VNADILHFQE DDESPWGFSR LNFDDCHVGK KLVTKKVGVD
510 520 530 540 550
DDDEDSVNDM EDVTNLYKNP EGSTSERLAV LTAIRKSRKA RIQYDIALPH
560 570 580 590 600
EEDVVFRLDE IDTIDYGQSF RVIVRIENNS EEPRTIQATM AANSVFYTGV
610 620 630 640 650
SAYDLKKASG TMHLKGRTTE IMHITITPEE YLDKLVDHSL VKIFSIATVK
660 670 680 690 700
ETKQNWSKED YFSFTKPSID ITVSGHLKVG YPVTAYFTFK NPIYRRLTDC
710 720 730 740 750
TVSFEGPGLQ RPKLVNFADV EPNDDVHFTE TFVPKKSGPR KIMALFNSKL
760
LNNVTAPVIK
Length:760
Mass (Da):86,586
Last modified:November 2, 2010 - v1
Checksum:i5C1F17C3A53A0FBF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS235778 Genomic DNA. Translation: EEB16884.1.
RefSeqiXP_002429622.1. XM_002429577.1.

Genome annotation databases

EnsemblMetazoaiPHUM442960-RA; PHUM442960-PA; PHUM442960.
GeneIDi8230915.
KEGGiphu:Phum_PHUM442960.
VectorBaseiPHUM442960. Pediculus humanus.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS235778 Genomic DNA. Translation: EEB16884.1.
RefSeqiXP_002429622.1. XM_002429577.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiPHUM442960-RA; PHUM442960-PA; PHUM442960.
GeneIDi8230915.
KEGGiphu:Phum_PHUM442960.
VectorBaseiPHUM442960. Pediculus humanus.

Organism-specific databases

CTDi8230915.

Phylogenomic databases

InParanoidiE0VU28.
KOiK05619.
OMAiHEINGDI.
OrthoDBiEOG7B8S3J.
PhylomeDBiE0VU28.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Genome sequences of the human body louse and its primary endosymbiont provide insights into the permanent parasitic lifestyle."
    Kirkness E.F., Haas B.J., Sun W., Braig H.R., Perotti M.A., Clark J.M., Lee S.H., Robertson H.M., Kennedy R.C., Elhaik E., Gerlach D., Kriventseva E.V., Elsik C.G., Graur D., Hill C.A., Veenstra J.A., Walenz B., Tubio J.M.
    , Ribeiro J.M., Rozas J., Johnston J.S., Reese J.T., Popadic A., Tojo M., Raoult D., Reed D.L., Tomoyasu Y., Krause E., Mittapalli O., Margam V.M., Li H.M., Meyer J.M., Johnson R.M., Romero-Severson J., Vanzee J.P., Alvarez-Ponce D., Vieira F.G., Aguade M., Guirao-Rico S., Anzola J.M., Yoon K.S., Strycharz J.P., Unger M.F., Christley S., Lobo N.F., Seufferheld M.J., Wang N., Dasch G.A., Struchiner C.J., Madey G., Hannick L.I., Bidwell S., Joardar V., Caler E., Shao R., Barker S.C., Cameron S., Bruggner R.V., Regier A., Johnson J., Viswanathan L., Utterback T.R., Sutton G.G., Lawson D., Waterhouse R.M., Venter J.C., Strausberg R.L., Berenbaum M.R., Collins F.H., Zdobnov E.M., Pittendrigh B.R.
    Proc. Natl. Acad. Sci. U.S.A. 107:12168-12173(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: USDAImported.

Entry informationi

Entry nameiE0VU28_PEDHC
AccessioniPrimary (citable) accession number: E0VU28
Entry historyi
Integrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 2, 2010
Last modified: January 7, 2015
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.