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E0VU28

- E0VU28_PEDHC

UniProt

E0VU28 - E0VU28_PEDHC

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Protein
Submitted name:

Hemocyte protein-glutamine gamma-glutamyltransferase, putative

Gene
Phum_PHUM442960
Organism
Pediculus humanus subsp. corporis (Body louse)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein inferred from homologyi

Functioni

Cofactori

Binds 1 calcium ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei336 – 3361 By similarityUniRule annotation
Active sitei399 – 3991 By similarityUniRule annotation
Active sitei422 – 4221 By similarityUniRule annotation
Metal bindingi462 – 4621Calcium By similarityUniRule annotation
Metal bindingi464 – 4641Calcium By similarityUniRule annotation
Metal bindingi521 – 5211Calcium By similarityUniRule annotation
Metal bindingi526 – 5261Calcium By similarityUniRule annotation

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein-glutamine gamma-glutamyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. peptide cross-linking Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

AcyltransferaseImported, Transferase

Keywords - Ligandi

CalciumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Hemocyte protein-glutamine gamma-glutamyltransferase, putativeImported (EC:2.3.2.13Imported)
Gene namesi
ORF Names:Phum_PHUM442960Imported
OrganismiPediculus humanus subsp. corporis (Body louse)
Taxonomic identifieri121224 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraParaneopteraPhthirapteraAnopluraPediculidaePediculus
ProteomesiUP000009046: Partially assembled WGS sequence

Family & Domainsi

Phylogenomic databases

KOiK05619.
OMAiHEINGDI.
OrthoDBiEOG7B8S3J.
PhylomeDBiE0VU28.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.

Sequencei

Sequence statusi: Complete.

E0VU28-1 [UniParc]FASTAAdd to Basket

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MSLRNDMGFY NGRSNNQNRN PEITNYMSNL MKKFNKDYER RRKQDENFSH    50
HFMGSPEFNI LTTMDVEFYA IENSKTHHTD KFELVQQDPK IPILRRGQHF 100
FIAVKFNRKI NFENDVIRLI FIFGPKPSVN KGTRAIVQVV KKDELNEDKW 150
DAAVHEINGD IVSIKVNIPV VSPVGLWNLN IQTSSTDVTS SFKNYKCKKD 200
IYVLFNPWCK DDEVYLEDEN ERNEYVLNDT GKIWMGSYLK PKGRRWFYGQ 250
FDDVVLPAVV HLLEKSKLKH GERGNVIQMA RAISAVVNSE DEDGLIEGKW 300
VGDFAGGTSP FAWTGSVAIM ENYLKSNGKS VKYGQCWVFS GAAVTICRAL 350
GIPARPVTNY ASAHDTNSSL TLDKYFTRDG TEIEGGPDGD CYDSCWNFHV 400
WVDVWMKRPD LPPSFSGWQI IDSTPQELSD NAYKCGPAPI EAVRRGEIGY 450
LYDTPFAFAA VNADILHFQE DDESPWGFSR LNFDDCHVGK KLVTKKVGVD 500
DDDEDSVNDM EDVTNLYKNP EGSTSERLAV LTAIRKSRKA RIQYDIALPH 550
EEDVVFRLDE IDTIDYGQSF RVIVRIENNS EEPRTIQATM AANSVFYTGV 600
SAYDLKKASG TMHLKGRTTE IMHITITPEE YLDKLVDHSL VKIFSIATVK 650
ETKQNWSKED YFSFTKPSID ITVSGHLKVG YPVTAYFTFK NPIYRRLTDC 700
TVSFEGPGLQ RPKLVNFADV EPNDDVHFTE TFVPKKSGPR KIMALFNSKL 750
LNNVTAPVIK 760
Length:760
Mass (Da):86,586
Last modified:November 2, 2010 - v1
Checksum:i5C1F17C3A53A0FBF
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS235778 Genomic DNA. Translation: EEB16884.1.
RefSeqiXP_002429622.1. XM_002429577.1.

Genome annotation databases

GeneIDi8230915.
KEGGiphu:Phum_PHUM442960.
VectorBaseiPHUM442960. Pediculus humanus.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS235778 Genomic DNA. Translation: EEB16884.1 .
RefSeqi XP_002429622.1. XM_002429577.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 8230915.
KEGGi phu:Phum_PHUM442960.
VectorBasei PHUM442960. Pediculus humanus.

Organism-specific databases

CTDi 8230915.

Phylogenomic databases

KOi K05619.
OMAi HEINGDI.
OrthoDBi EOG7B8S3J.
PhylomeDBi E0VU28.

Family and domain databases

Gene3Di 2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProi IPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR001102. Transglutaminase_N.
[Graphical view ]
PANTHERi PTHR11590. PTHR11590. 1 hit.
Pfami PF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000459. TGM_EBP42. 1 hit.
SMARTi SM00460. TGc. 1 hit.
[Graphical view ]
SUPFAMi SSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Genome sequences of the human body louse and its primary endosymbiont provide insights into the permanent parasitic lifestyle."
    Kirkness E.F., Haas B.J., Sun W., Braig H.R., Perotti M.A., Clark J.M., Lee S.H., Robertson H.M., Kennedy R.C., Elhaik E., Gerlach D., Kriventseva E.V., Elsik C.G., Graur D., Hill C.A., Veenstra J.A., Walenz B., Tubio J.M.
    , Ribeiro J.M., Rozas J., Johnston J.S., Reese J.T., Popadic A., Tojo M., Raoult D., Reed D.L., Tomoyasu Y., Krause E., Mittapalli O., Margam V.M., Li H.M., Meyer J.M., Johnson R.M., Romero-Severson J., Vanzee J.P., Alvarez-Ponce D., Vieira F.G., Aguade M., Guirao-Rico S., Anzola J.M., Yoon K.S., Strycharz J.P., Unger M.F., Christley S., Lobo N.F., Seufferheld M.J., Wang N., Dasch G.A., Struchiner C.J., Madey G., Hannick L.I., Bidwell S., Joardar V., Caler E., Shao R., Barker S.C., Cameron S., Bruggner R.V., Regier A., Johnson J., Viswanathan L., Utterback T.R., Sutton G.G., Lawson D., Waterhouse R.M., Venter J.C., Strausberg R.L., Berenbaum M.R., Collins F.H., Zdobnov E.M., Pittendrigh B.R.
    Proc. Natl. Acad. Sci. U.S.A. 107:12168-12173(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: USDA.

Entry informationi

Entry nameiE0VU28_PEDHC
AccessioniPrimary (citable) accession number: E0VU28
Entry historyi
Integrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 2, 2010
Last modified: July 9, 2014
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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