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E0VU28

- E0VU28_PEDHC

UniProt

E0VU28 - E0VU28_PEDHC

Protein
Submitted name:

Hemocyte protein-glutamine gamma-glutamyltransferase, putative

Gene

Phum_PHUM442960

Organism
Pediculus humanus subsp. corporis (Body louse)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 23 (01 Oct 2014)
      Sequence version 1 (02 Nov 2010)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 calcium ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei336 – 3361UniRule annotation
    Active sitei399 – 3991UniRule annotation
    Active sitei422 – 4221UniRule annotation
    Metal bindingi462 – 4621Calcium
    Metal bindingi464 – 4641Calcium
    Metal bindingi521 – 5211Calcium
    Metal bindingi526 – 5261Calcium

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. protein-glutamine gamma-glutamyltransferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. peptide cross-linking Source: InterPro

    Keywords - Molecular functioni

    AcyltransferaseImported, Transferase

    Keywords - Ligandi

    CalciumUniRule annotation, Metal-bindingUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Hemocyte protein-glutamine gamma-glutamyltransferase, putativeImported (EC:2.3.2.13Imported)
    Gene namesi
    ORF Names:Phum_PHUM442960Imported
    OrganismiPediculus humanus subsp. corporis (Body louse)Imported
    Taxonomic identifieri121224 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraParaneopteraPhthirapteraAnopluraPediculidaePediculus
    ProteomesiUP000009046: Partially assembled WGS sequence

    Family & Domainsi

    Phylogenomic databases

    KOiK05619.
    OMAiHEINGDI.
    OrthoDBiEOG7B8S3J.
    PhylomeDBiE0VU28.

    Family and domain databases

    Gene3Di2.60.40.10. 3 hits.
    3.90.260.10. 1 hit.
    InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
    IPR013783. Ig-like_fold.
    IPR014756. Ig_E-set.
    IPR002931. Transglutaminase-like.
    IPR008958. Transglutaminase_C.
    IPR001102. Transglutaminase_N.
    [Graphical view]
    PANTHERiPTHR11590. PTHR11590. 1 hit.
    PfamiPF00927. Transglut_C. 2 hits.
    PF01841. Transglut_core. 1 hit.
    PF00868. Transglut_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
    SMARTiSM00460. TGc. 1 hit.
    [Graphical view]
    SUPFAMiSSF49309. SSF49309. 2 hits.
    SSF81296. SSF81296. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    E0VU28-1 [UniParc]FASTAAdd to Basket

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    MSLRNDMGFY NGRSNNQNRN PEITNYMSNL MKKFNKDYER RRKQDENFSH    50
    HFMGSPEFNI LTTMDVEFYA IENSKTHHTD KFELVQQDPK IPILRRGQHF 100
    FIAVKFNRKI NFENDVIRLI FIFGPKPSVN KGTRAIVQVV KKDELNEDKW 150
    DAAVHEINGD IVSIKVNIPV VSPVGLWNLN IQTSSTDVTS SFKNYKCKKD 200
    IYVLFNPWCK DDEVYLEDEN ERNEYVLNDT GKIWMGSYLK PKGRRWFYGQ 250
    FDDVVLPAVV HLLEKSKLKH GERGNVIQMA RAISAVVNSE DEDGLIEGKW 300
    VGDFAGGTSP FAWTGSVAIM ENYLKSNGKS VKYGQCWVFS GAAVTICRAL 350
    GIPARPVTNY ASAHDTNSSL TLDKYFTRDG TEIEGGPDGD CYDSCWNFHV 400
    WVDVWMKRPD LPPSFSGWQI IDSTPQELSD NAYKCGPAPI EAVRRGEIGY 450
    LYDTPFAFAA VNADILHFQE DDESPWGFSR LNFDDCHVGK KLVTKKVGVD 500
    DDDEDSVNDM EDVTNLYKNP EGSTSERLAV LTAIRKSRKA RIQYDIALPH 550
    EEDVVFRLDE IDTIDYGQSF RVIVRIENNS EEPRTIQATM AANSVFYTGV 600
    SAYDLKKASG TMHLKGRTTE IMHITITPEE YLDKLVDHSL VKIFSIATVK 650
    ETKQNWSKED YFSFTKPSID ITVSGHLKVG YPVTAYFTFK NPIYRRLTDC 700
    TVSFEGPGLQ RPKLVNFADV EPNDDVHFTE TFVPKKSGPR KIMALFNSKL 750
    LNNVTAPVIK 760
    Length:760
    Mass (Da):86,586
    Last modified:November 2, 2010 - v1
    Checksum:i5C1F17C3A53A0FBF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS235778 Genomic DNA. Translation: EEB16884.1.
    RefSeqiXP_002429622.1. XM_002429577.1.

    Genome annotation databases

    GeneIDi8230915.
    KEGGiphu:Phum_PHUM442960.
    VectorBaseiPHUM442960. Pediculus humanus.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS235778 Genomic DNA. Translation: EEB16884.1 .
    RefSeqi XP_002429622.1. XM_002429577.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 8230915.
    KEGGi phu:Phum_PHUM442960.
    VectorBasei PHUM442960. Pediculus humanus.

    Organism-specific databases

    CTDi 8230915.

    Phylogenomic databases

    KOi K05619.
    OMAi HEINGDI.
    OrthoDBi EOG7B8S3J.
    PhylomeDBi E0VU28.

    Family and domain databases

    Gene3Di 2.60.40.10. 3 hits.
    3.90.260.10. 1 hit.
    InterProi IPR023608. Gln_gamma-glutamylTfrase_euk.
    IPR013783. Ig-like_fold.
    IPR014756. Ig_E-set.
    IPR002931. Transglutaminase-like.
    IPR008958. Transglutaminase_C.
    IPR001102. Transglutaminase_N.
    [Graphical view ]
    PANTHERi PTHR11590. PTHR11590. 1 hit.
    Pfami PF00927. Transglut_C. 2 hits.
    PF01841. Transglut_core. 1 hit.
    PF00868. Transglut_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000459. TGM_EBP42. 1 hit.
    SMARTi SM00460. TGc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49309. SSF49309. 2 hits.
    SSF81296. SSF81296. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequences of the human body louse and its primary endosymbiont provide insights into the permanent parasitic lifestyle."
      Kirkness E.F., Haas B.J., Sun W., Braig H.R., Perotti M.A., Clark J.M., Lee S.H., Robertson H.M., Kennedy R.C., Elhaik E., Gerlach D., Kriventseva E.V., Elsik C.G., Graur D., Hill C.A., Veenstra J.A., Walenz B., Tubio J.M.
      , Ribeiro J.M., Rozas J., Johnston J.S., Reese J.T., Popadic A., Tojo M., Raoult D., Reed D.L., Tomoyasu Y., Krause E., Mittapalli O., Margam V.M., Li H.M., Meyer J.M., Johnson R.M., Romero-Severson J., Vanzee J.P., Alvarez-Ponce D., Vieira F.G., Aguade M., Guirao-Rico S., Anzola J.M., Yoon K.S., Strycharz J.P., Unger M.F., Christley S., Lobo N.F., Seufferheld M.J., Wang N., Dasch G.A., Struchiner C.J., Madey G., Hannick L.I., Bidwell S., Joardar V., Caler E., Shao R., Barker S.C., Cameron S., Bruggner R.V., Regier A., Johnson J., Viswanathan L., Utterback T.R., Sutton G.G., Lawson D., Waterhouse R.M., Venter J.C., Strausberg R.L., Berenbaum M.R., Collins F.H., Zdobnov E.M., Pittendrigh B.R.
      Proc. Natl. Acad. Sci. U.S.A. 107:12168-12173(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: USDAImported.

    Entry informationi

    Entry nameiE0VU28_PEDHC
    AccessioniPrimary (citable) accession number: E0VU28
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 2, 2010
    Last sequence update: November 2, 2010
    Last modified: October 1, 2014
    This is version 23 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3