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Protein
Submitted name:

N-acetylgalactosamine kinase, putative

Gene

Phum_PHUM424860

Organism
Pediculus humanus subsp. corporis (Body louse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationImported, Transferase

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
N-acetylgalactosamine kinase, putativeImported (EC:2.7.1.157Imported)
Gene namesi
ORF Names:Phum_PHUM424860Imported
OrganismiPediculus humanus subsp. corporis (Body louse)Imported
Taxonomic identifieri121224 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraParaneopteraPhthirapteraAnopluraPediculidaePediculus
ProteomesiUP000009046 Componenti: Partially assembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliE0VT04.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GHMP kinase family.UniRule annotation

Phylogenomic databases

InParanoidiE0VT04.
KOiK18674.
OMAiCKCLGIS.
OrthoDBiEOG790G0V.
PhylomeDBiE0VT04.

Family and domain databases

Gene3Di3.30.230.10. 1 hit.
3.30.70.890. 2 hits.
InterProiIPR000705. Galactokinase.
IPR019741. Galactokinase_CS.
IPR019539. GalKase_gal-bd.
IPR013750. GHMP_kinase_C_dom.
IPR006204. GHMP_kinase_N_dom.
IPR006203. GHMP_knse_ATP-bd_CS.
IPR006206. Mevalonate/galactokinase.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
[Graphical view]
PfamiPF10509. GalKase_gal_bdg. 1 hit.
PF08544. GHMP_kinases_C. 1 hit.
PF00288. GHMP_kinases_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000530. Galactokinase. 1 hit.
PRINTSiPR00473. GALCTOKINASE.
PR00959. MEVGALKINASE.
SUPFAMiSSF54211. SSF54211. 1 hit.
SSF55060. SSF55060. 2 hits.
TIGRFAMsiTIGR00131. gal_kin. 1 hit.
PROSITEiPS00106. GALACTOKINASE. 1 hit.
PS00627. GHMP_KINASES_ATP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E0VT04-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDLNSVSEG NYPPVYPLPN DEDIITLTKY FKKKYNEEPD FYARAPGRVN
60 70 80 90 100
LIGEHVDYCG YSVCPMAVQQ HVVIAFKLSD DSVVKISNVD ETYNSYECSI
110 120 130 140 150
NDVNIPENVL PEWHFYFLCG VKGVLEKLPP ETTRRGFRAS VYGNIPLGSG
160 170 180 190 200
LSSSSALVSA VTLALSRAYN LTLTKEELAD LAAKSERYIG TLGGGMDQAI
210 220 230 240 250
SFLATKGCAK HISFDPLKST DLKLPDGALF VIAHSLIQMN KAATQDFNCR
260 270 280 290 300
VVECRLACQV LAKRLRLDWK RINKLAFLQK SIGLGVRHLR ALATETLHEE
310 320 330 340 350
PYTKDEICKE LQITQEELNK TSLTENTKHI QHFKLKQRML HVTEEVERVM
360 370 380 390 400
EFIRICKEAE KGTMSSESAL YSLGKLLKKS HESLKNLYEC SHEELDKIIK
410 420 430 440 450
LAENHTLGAR LTGAGWGGCT VALTAKDKVE DYIETLKEEF YRCNERAEDL
460 470
DLDNLVFVTE PGNGAAIFIK S
Length:471
Mass (Da):52,820
Last modified:November 2, 2010 - v1
Checksum:i951E3F150188AF94
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS235759 Genomic DNA. Translation: EEB16510.1.
RefSeqiXP_002429248.1. XM_002429203.1.

Genome annotation databases

EnsemblMetazoaiPHUM424860-RA; PHUM424860-PA; PHUM424860.
GeneIDi8230109.
KEGGiphu:Phum_PHUM424860.
VectorBaseiPHUM424860. Pediculus humanus.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS235759 Genomic DNA. Translation: EEB16510.1.
RefSeqiXP_002429248.1. XM_002429203.1.

3D structure databases

ProteinModelPortaliE0VT04.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiPHUM424860-RA; PHUM424860-PA; PHUM424860.
GeneIDi8230109.
KEGGiphu:Phum_PHUM424860.
VectorBaseiPHUM424860. Pediculus humanus.

Organism-specific databases

CTDi8230109.

Phylogenomic databases

InParanoidiE0VT04.
KOiK18674.
OMAiCKCLGIS.
OrthoDBiEOG790G0V.
PhylomeDBiE0VT04.

Family and domain databases

Gene3Di3.30.230.10. 1 hit.
3.30.70.890. 2 hits.
InterProiIPR000705. Galactokinase.
IPR019741. Galactokinase_CS.
IPR019539. GalKase_gal-bd.
IPR013750. GHMP_kinase_C_dom.
IPR006204. GHMP_kinase_N_dom.
IPR006203. GHMP_knse_ATP-bd_CS.
IPR006206. Mevalonate/galactokinase.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
[Graphical view]
PfamiPF10509. GalKase_gal_bdg. 1 hit.
PF08544. GHMP_kinases_C. 1 hit.
PF00288. GHMP_kinases_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000530. Galactokinase. 1 hit.
PRINTSiPR00473. GALCTOKINASE.
PR00959. MEVGALKINASE.
SUPFAMiSSF54211. SSF54211. 1 hit.
SSF55060. SSF55060. 2 hits.
TIGRFAMsiTIGR00131. gal_kin. 1 hit.
PROSITEiPS00106. GALACTOKINASE. 1 hit.
PS00627. GHMP_KINASES_ATP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequences of the human body louse and its primary endosymbiont provide insights into the permanent parasitic lifestyle."
    Kirkness E.F., Haas B.J., Sun W., Braig H.R., Perotti M.A., Clark J.M., Lee S.H., Robertson H.M., Kennedy R.C., Elhaik E., Gerlach D., Kriventseva E.V., Elsik C.G., Graur D., Hill C.A., Veenstra J.A., Walenz B., Tubio J.M.
    , Ribeiro J.M., Rozas J., Johnston J.S., Reese J.T., Popadic A., Tojo M., Raoult D., Reed D.L., Tomoyasu Y., Krause E., Mittapalli O., Margam V.M., Li H.M., Meyer J.M., Johnson R.M., Romero-Severson J., Vanzee J.P., Alvarez-Ponce D., Vieira F.G., Aguade M., Guirao-Rico S., Anzola J.M., Yoon K.S., Strycharz J.P., Unger M.F., Christley S., Lobo N.F., Seufferheld M.J., Wang N., Dasch G.A., Struchiner C.J., Madey G., Hannick L.I., Bidwell S., Joardar V., Caler E., Shao R., Barker S.C., Cameron S., Bruggner R.V., Regier A., Johnson J., Viswanathan L., Utterback T.R., Sutton G.G., Lawson D., Waterhouse R.M., Venter J.C., Strausberg R.L., Berenbaum M.R., Collins F.H., Zdobnov E.M., Pittendrigh B.R.
    Proc. Natl. Acad. Sci. U.S.A. 107:12168-12173(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: USDAImported.

Entry informationi

Entry nameiE0VT04_PEDHC
AccessioniPrimary (citable) accession number: E0VT04
Entry historyi
Integrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 2, 2010
Last modified: January 7, 2015
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.