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Protein

Hexokinase

Gene

Phum_PHUM419880

Organism
Pediculus humanus subsp. corporis (Body louse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-hexose = ADP + D-hexose 6-phosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
HexokinaseUniRule annotation (EC:2.7.1.1UniRule annotation)
Gene namesi
ORF Names:Phum_PHUM419880Imported
OrganismiPediculus humanus subsp. corporis (Body louse)Imported
Taxonomic identifieri121224 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraParaneopteraPhthirapteraAnopluraPediculidaePediculus
ProteomesiUP000009046 Componenti: Partially assembled WGS sequence

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation

Phylogenomic databases

InParanoidiE0VSJ4.
KOiK00844.
OMAiGENICHL.
OrthoDBiEOG7S21X5.
PhylomeDBiE0VSJ4.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR019807. Hexokinase_BS.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PROSITEiPS00378. HEXOKINASE_1. 1 hit.
PS51748. HEXOKINASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E0VSJ4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVRSWPRNPC VNLSKKVKKK CHSLILNNDQ LFRVKKLLLD SLKKGLKKET
60 70 80 90 100
HPEAIIKCFP TYVQDLPNGK EKGKFLALDL GGTNFRVLII YLEENHFDMK
110 120 130 140 150
SKIYPVPEAI MLGTGTQLFD HIAECLATFT KENNVNTERL PLGFTFSFPL
160 170 180 190 200
RQKALTTGLL ERWTKGFNCS GVIGEDVVRL LREALQRRHD VQIDVCAILN
210 220 230 240 250
DTTGTLMSCA WKNQNCRIGL IVGTGSNACY VEKTDEVETF NGCNKKPYVV
260 270 280 290 300
VNTEWGAFGD DGCLDFIRTS YDIDLDKNSI NPGKQVFEKM ISGMYIGELV
310 320 330 340 350
RLIIVHFIEL GLLFNGNSSE IIEKKWHFLT KYVSEIESEK KGVFDKCQNV
360 370 380 390 400
LKTVGIGSVT DEDCANVRYI CQCVSRRAAH IVSAGIATLI DKIGQNNITV
410 420 430 440 450
AVDGSVYRYH PHFHNLMMAK TSELLVNPAK FDFMLSEDGS GRGAALVAAV
460
AYRVSITILH
Length:460
Mass (Da):51,573
Last modified:November 2, 2010 - v1
Checksum:i44A0E4A7895B7E6F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS235751 Genomic DNA. Translation: EEB16350.1.
RefSeqiXP_002429088.1. XM_002429043.1.

Genome annotation databases

EnsemblMetazoaiPHUM419880-RA; PHUM419880-PA; PHUM419880.
GeneIDi8234467.
KEGGiphu:Phum_PHUM419880.
VectorBaseiPHUM419880. Pediculus humanus.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS235751 Genomic DNA. Translation: EEB16350.1.
RefSeqiXP_002429088.1. XM_002429043.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiPHUM419880-RA; PHUM419880-PA; PHUM419880.
GeneIDi8234467.
KEGGiphu:Phum_PHUM419880.
VectorBaseiPHUM419880. Pediculus humanus.

Organism-specific databases

CTDi8234467.

Phylogenomic databases

InParanoidiE0VSJ4.
KOiK00844.
OMAiGENICHL.
OrthoDBiEOG7S21X5.
PhylomeDBiE0VSJ4.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR019807. Hexokinase_BS.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PROSITEiPS00378. HEXOKINASE_1. 1 hit.
PS51748. HEXOKINASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequences of the human body louse and its primary endosymbiont provide insights into the permanent parasitic lifestyle."
    Kirkness E.F., Haas B.J., Sun W., Braig H.R., Perotti M.A., Clark J.M., Lee S.H., Robertson H.M., Kennedy R.C., Elhaik E., Gerlach D., Kriventseva E.V., Elsik C.G., Graur D., Hill C.A., Veenstra J.A., Walenz B., Tubio J.M.
    , Ribeiro J.M., Rozas J., Johnston J.S., Reese J.T., Popadic A., Tojo M., Raoult D., Reed D.L., Tomoyasu Y., Krause E., Mittapalli O., Margam V.M., Li H.M., Meyer J.M., Johnson R.M., Romero-Severson J., Vanzee J.P., Alvarez-Ponce D., Vieira F.G., Aguade M., Guirao-Rico S., Anzola J.M., Yoon K.S., Strycharz J.P., Unger M.F., Christley S., Lobo N.F., Seufferheld M.J., Wang N., Dasch G.A., Struchiner C.J., Madey G., Hannick L.I., Bidwell S., Joardar V., Caler E., Shao R., Barker S.C., Cameron S., Bruggner R.V., Regier A., Johnson J., Viswanathan L., Utterback T.R., Sutton G.G., Lawson D., Waterhouse R.M., Venter J.C., Strausberg R.L., Berenbaum M.R., Collins F.H., Zdobnov E.M., Pittendrigh B.R.
    Proc. Natl. Acad. Sci. U.S.A. 107:12168-12173(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: USDAImported.

Entry informationi

Entry nameiE0VSJ4_PEDHC
AccessioniPrimary (citable) accession number: E0VSJ4
Entry historyi
Integrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 2, 2010
Last modified: July 22, 2015
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.