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Protein
Submitted name:

Tripsin, putative

Gene

Phum_PHUM375640

Organism
Pediculus humanus subsp. corporis (Body louse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionHydrolaseImported

Protein family/group databases

MEROPSiS01.492.

Names & Taxonomyi

Protein namesi
Submitted name:
Tripsin, putativeImported (EC:3.4.21.4Imported)
Gene namesi
ORF Names:Phum_PHUM375640Imported
OrganismiPediculus humanus subsp. corporis (Body louse)Imported
Taxonomic identifieri121224 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraParaneopteraPhthirapteraAnopluraPediculidaePediculus
Proteomesi
  • UP000009046 Componenti: Partially assembled WGS sequence

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_500314193725 – 401Sequence analysisAdd BLAST377

Keywords - PTMi

Disulfide bondSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliE0VQA9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini29 – 143CUBInterPro annotationAdd BLAST115
Domaini161 – 395Peptidase S1InterPro annotationAdd BLAST235

Sequence similaritiesi

Belongs to the peptidase S1 family.SAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

InParanoidiE0VQA9.
KOiK01312.
OMAiEWNYCYQ.
PhylomeDBiE0VQA9.

Family and domain databases

CDDicd00041. CUB. 1 hit.
cd00190. Tryp_SPc. 1 hit.
Gene3Di2.60.120.290. 1 hit.
InterProiView protein in InterPro
IPR000859. CUB_dom.
IPR009003. Peptidase_S1_PA.
IPR001314. Peptidase_S1A.
IPR001254. Trypsin_dom.
IPR018114. TRYPSIN_HIS.
PfamiView protein in Pfam
PF00431. CUB. 1 hit.
PF00089. Trypsin. 1 hit.
PRINTSiPR00722. CHYMOTRYPSIN.
SMARTiView protein in SMART
SM00020. Tryp_SPc. 1 hit.
SUPFAMiSSF49854. SSF49854. 1 hit.
SSF50494. SSF50494. 1 hit.
PROSITEiView protein in PROSITE
PS01180. CUB. 1 hit.
PS50240. TRYPSIN_DOM. 1 hit.
PS00134. TRYPSIN_HIS. 1 hit.

Sequencei

Sequence statusi: Complete.

E0VQA9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGKMFFFKH IVFLIIFFVK TCYCIFENCD YYQDLQPNKI YHIFSPGYPE
60 70 80 90 100
NYVPGTKCRW YAVAPVQNKI SLQCEVVKIP VSDNCRQDKF AVSLEGRIDL
110 120 130 140 150
KDVKFYCGEG TLNVTSVGNK LNVILWSVTN QVGSLFCTVK IIQNESPVKK
160 170 180 190 200
CICGQRNSVR IVGGVETGVN EYPMMAGLVD GNLRVLFCGG TIISNFYVVT
210 220 230 240 250
AAHCVWDRQA RSLAVLVGDH DISVGNDTDS AKLYRASSIR VHPQYDTANQ
260 270 280 290 300
KNDIALVKIK NKISFNMRVG PVCLPFKNID NTFVGEKVYA LGWGATSFGG
310 320 330 340 350
PTSNKLLHVP LDVISVKQCR PSYGDLVSKR QICTYGENKD SCQSDSGGPI
360 370 380 390 400
LWTDPSTGAL NLLGLVSYGI QCGTTHPSVN TRVSSYLKWI QTATGEEYCV

L
Length:401
Mass (Da):44,411
Last modified:November 2, 2010 - v1
Checksum:i0A32EA01E9E870EF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS235408 Genomic DNA. Translation: EEB15565.1.
RefSeqiXP_002428303.1. XM_002428258.1.

Genome annotation databases

EnsemblMetazoaiPHUM375640-RA; PHUM375640-PA; PHUM375640.
GeneIDi8240203.
KEGGiphu:Phum_PHUM375640.
VectorBaseiPHUM375640-RA; PHUM375640-PA; PHUM375640.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS235408 Genomic DNA. Translation: EEB15565.1.
RefSeqiXP_002428303.1. XM_002428258.1.

3D structure databases

ProteinModelPortaliE0VQA9.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

MEROPSiS01.492.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiPHUM375640-RA; PHUM375640-PA; PHUM375640.
GeneIDi8240203.
KEGGiphu:Phum_PHUM375640.
VectorBaseiPHUM375640-RA; PHUM375640-PA; PHUM375640.

Organism-specific databases

CTDi8240203.

Phylogenomic databases

InParanoidiE0VQA9.
KOiK01312.
OMAiEWNYCYQ.
PhylomeDBiE0VQA9.

Family and domain databases

CDDicd00041. CUB. 1 hit.
cd00190. Tryp_SPc. 1 hit.
Gene3Di2.60.120.290. 1 hit.
InterProiView protein in InterPro
IPR000859. CUB_dom.
IPR009003. Peptidase_S1_PA.
IPR001314. Peptidase_S1A.
IPR001254. Trypsin_dom.
IPR018114. TRYPSIN_HIS.
PfamiView protein in Pfam
PF00431. CUB. 1 hit.
PF00089. Trypsin. 1 hit.
PRINTSiPR00722. CHYMOTRYPSIN.
SMARTiView protein in SMART
SM00020. Tryp_SPc. 1 hit.
SUPFAMiSSF49854. SSF49854. 1 hit.
SSF50494. SSF50494. 1 hit.
PROSITEiView protein in PROSITE
PS01180. CUB. 1 hit.
PS50240. TRYPSIN_DOM. 1 hit.
PS00134. TRYPSIN_HIS. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiE0VQA9_PEDHC
AccessioniPrimary (citable) accession number: E0VQA9
Entry historyiIntegrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 2, 2010
Last modified: February 15, 2017
This is version 40 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.