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Protein
Submitted name:

Neuroendocrine convertase 2, putative

Gene

8232027

Organism
Pediculus humanus subsp. corporis (Body louse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protease, Serine proteaseUniRule annotationSAAS annotation

Protein family/group databases

MEROPSiS08.109.

Names & Taxonomyi

Protein namesi
Submitted name:
Neuroendocrine convertase 2, putativeImported (EC:3.4.21.94Imported)
Gene namesi
Name:8232027Imported
ORF Names:Phum_PHUM354430Imported
OrganismiPediculus humanus subsp. corporis (Body louse)Imported
Taxonomic identifieri121224 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraParaneopteraPsocodeaPhthirapteraAnopluraPediculidaePediculus
Proteomesi
  • UP000009046 Componenti: Partially assembled WGS sequence

Structurei

3D structure databases

ProteinModelPortaliE0VP88.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 50S8_pro-domainInterPro annotationAdd BLAST49
Domaini107 – 368Peptidase S8InterPro annotationAdd BLAST262
Domaini454 – 540P_proproteinInterPro annotationAdd BLAST87

Sequence similaritiesi

Belongs to the peptidase S8 family.UniRule annotation

Phylogenomic databases

InParanoidiE0VP88.
KOiK01360.
OMAiTDACQGK.
PhylomeDBiE0VP88.

Family and domain databases

CDDicd04059. Peptidases_S8_Protein_converta. 1 hit.
Gene3Di2.60.120.260. 1 hit.
3.40.50.200. 1 hit.
InterProiView protein in InterPro
IPR008979. Galactose-bd-like.
IPR034182. Kexin/furin.
IPR009020. Peptidase/Inhibitor_I9.
IPR000209. Peptidase_S8/S53_dom.
IPR023827. Peptidase_S8_Asp-AS.
IPR022398. Peptidase_S8_His-AS.
IPR023828. Peptidase_S8_Ser-AS.
IPR015500. Peptidase_S8_subtilisin-rel.
IPR002884. PrprotnconvertsP.
IPR032815. S8_pro-domain.
PfamiView protein in Pfam
PF01483. P_proprotein. 1 hit.
PF00082. Peptidase_S8. 1 hit.
PF16470. S8_pro-domain. 1 hit.
PRINTSiPR00723. SUBTILISIN.
SUPFAMiSSF49785. SSF49785. 1 hit.
SSF52743. SSF52743. 1 hit.
SSF54897. SSF54897. 1 hit.
PROSITEiView protein in PROSITE
PS00136. SUBTILASE_ASP. 1 hit.
PS00137. SUBTILASE_HIS. 1 hit.
PS00138. SUBTILASE_SER. 1 hit.

Sequencei

Sequence statusi: Fragment.

E0VP88-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
VLGSKSEYHF INHAVPHARS RRSITHARKL KKDPQVVYAV QQVGFKREKR
60 70 80 90 100
GFKPLKVENL VQFMRPQDDP TDPYFQFQWY LKNTGQNGGK PKLDLNVASA
110 120 130 140 150
WAQGITGKNV TTAIMDDGVD YMHADLKHNY NARASYDFSS NDPYPYPRYT
160 170 180 190 200
DDWFNSHGTR CAGEVAAARD NGVCGVGVAY DSKIAGIRML DQPYMTDLIE
210 220 230 240 250
ANSMGHEPNL IDIYSASWGP TDDGKTVDGP RNATMRAIVR GVNEGRNGLG
260 270 280 290 300
NIYVWASGDG GEDDDCNCDG YAASMWTISI NSAINDGQNA HYDESCSSTL
310 320 330 340 350
ASTFSNGAKD PNTGVATTDL YGKCTTTHSG TSAAAPEAAG VFALALEANP
360 370 380 390 400
ALTWRDIQHL TVLTSKRNSL FDAKGRFHWT MNGVGLEFNH LFGFGVLDAG
410 420 430 440 450
AMVALAKQWQ MVPARYHCEA GNLIGAYEIH SSRSLRLKIK TTACLGSDTQ
460 470 480 490 500
VSYLEHVQAV ITLNASRRGD VEMFLTSPMG TRSMILSKRS KDDDHRDGFI
510 520 530 540 550
KWPFMTTHSW GEYPQGTWIL EVNFNSESPQ IGFLKEWTLM LHGTREPPYS
560 570
GLKVSDSHSK LAIVKKAHEE NRKM
Length:574
Mass (Da):63,522
Last modified:November 2, 2010 - v1
Checksum:i0559C48F4D45C627
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS235357 Genomic DNA. Translation: EEB15194.1.
RefSeqiXP_002427932.1. XM_002427887.1.

Genome annotation databases

EnsemblMetazoaiPHUM354430-RA; PHUM354430-PA; PHUM354430.
GeneIDi8232027.
KEGGiphu:Phum_PHUM354430.
VectorBaseiPHUM354430-RA; PHUM354430-PA; PHUM354430.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS235357 Genomic DNA. Translation: EEB15194.1.
RefSeqiXP_002427932.1. XM_002427887.1.

3D structure databases

ProteinModelPortaliE0VP88.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

MEROPSiS08.109.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiPHUM354430-RA; PHUM354430-PA; PHUM354430.
GeneIDi8232027.
KEGGiphu:Phum_PHUM354430.
VectorBaseiPHUM354430-RA; PHUM354430-PA; PHUM354430.

Organism-specific databases

CTDi8232027.

Phylogenomic databases

InParanoidiE0VP88.
KOiK01360.
OMAiTDACQGK.
PhylomeDBiE0VP88.

Family and domain databases

CDDicd04059. Peptidases_S8_Protein_converta. 1 hit.
Gene3Di2.60.120.260. 1 hit.
3.40.50.200. 1 hit.
InterProiView protein in InterPro
IPR008979. Galactose-bd-like.
IPR034182. Kexin/furin.
IPR009020. Peptidase/Inhibitor_I9.
IPR000209. Peptidase_S8/S53_dom.
IPR023827. Peptidase_S8_Asp-AS.
IPR022398. Peptidase_S8_His-AS.
IPR023828. Peptidase_S8_Ser-AS.
IPR015500. Peptidase_S8_subtilisin-rel.
IPR002884. PrprotnconvertsP.
IPR032815. S8_pro-domain.
PfamiView protein in Pfam
PF01483. P_proprotein. 1 hit.
PF00082. Peptidase_S8. 1 hit.
PF16470. S8_pro-domain. 1 hit.
PRINTSiPR00723. SUBTILISIN.
SUPFAMiSSF49785. SSF49785. 1 hit.
SSF52743. SSF52743. 1 hit.
SSF54897. SSF54897. 1 hit.
PROSITEiView protein in PROSITE
PS00136. SUBTILASE_ASP. 1 hit.
PS00137. SUBTILASE_HIS. 1 hit.
PS00138. SUBTILASE_SER. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiE0VP88_PEDHC
AccessioniPrimary (citable) accession number: E0VP88
Entry historyiIntegrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 2, 2010
Last modified: May 10, 2017
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.