E0VP88 (E0VP88_PEDHC) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Neuroendocrine convertase 2, putative EMBL EEB15194.1
EC=3.4.21.94 EMBL EEB15194.1

Gene names

ORF Names:

Phum_PHUM354430 EMBL EEB15194.1

Organism

Pediculus humanus subsp. corporis (Body louse) [Reference proteome]

Taxonomic identifier

121224 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Paraneoptera › Phthiraptera › Anoplura › Pediculidae › Pediculus › Pediculus humanus

Protein attributes

Sequence length	574 AA.
Sequence status	Fragment.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the peptidase S8 family. RuleBase RU003355

Ontologies

Keywords
Molecular function	Hydrolase Protease Serine protease RuleBase RU004261 SAAS SAAS009020
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	proteolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	serine-type endopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL EEB15194.1

Sequences

	Sequence		Length	Mass (Da)
	E0VP88 [UniParc]. Last modified November 2, 2010. Version 1. Checksum: 0559C48F4D45C627	FASTA	574	63,522
	10 20 30 40 50 60 VLGSKSEYHF INHAVPHARS RRSITHARKL KKDPQVVYAV QQVGFKREKR GFKPLKVENL 70 80 90 100 110 120 VQFMRPQDDP TDPYFQFQWY LKNTGQNGGK PKLDLNVASA WAQGITGKNV TTAIMDDGVD 130 140 150 160 170 180 YMHADLKHNY NARASYDFSS NDPYPYPRYT DDWFNSHGTR CAGEVAAARD NGVCGVGVAY 190 200 210 220 230 240 DSKIAGIRML DQPYMTDLIE ANSMGHEPNL IDIYSASWGP TDDGKTVDGP RNATMRAIVR 250 260 270 280 290 300 GVNEGRNGLG NIYVWASGDG GEDDDCNCDG YAASMWTISI NSAINDGQNA HYDESCSSTL 310 320 330 340 350 360 ASTFSNGAKD PNTGVATTDL YGKCTTTHSG TSAAAPEAAG VFALALEANP ALTWRDIQHL 370 380 390 400 410 420 TVLTSKRNSL FDAKGRFHWT MNGVGLEFNH LFGFGVLDAG AMVALAKQWQ MVPARYHCEA 430 440 450 460 470 480 GNLIGAYEIH SSRSLRLKIK TTACLGSDTQ VSYLEHVQAV ITLNASRRGD VEMFLTSPMG 490 500 510 520 530 540 TRSMILSKRS KDDDHRDGFI KWPFMTTHSW GEYPQGTWIL EVNFNSESPQ IGFLKEWTLM 550 560 570 LHGTREPPYS GLKVSDSHSK LAIVKKAHEE NRKM

References

[1]

"Genome sequences of the human body louse and its primary endosymbiont provide insights into the permanent parasitic lifestyle." Kirkness E.F., Haas B.J., Sun W., Braig H.R., Perotti M.A., Clark J.M., Lee S.H., Robertson H.M., Kennedy R.C., Elhaik E., Gerlach D., Kriventseva E.V., Elsik C.G., Graur D., Hill C.A., Veenstra J.A., Walenz B., Tubio J.M. , Ribeiro J.M., Rozas J., Johnston J.S., Reese J.T., Popadic A., Tojo M., Raoult D., Reed D.L., Tomoyasu Y., Krause E., Mittapalli O., Margam V.M., Li H.M., Meyer J.M., Johnson R.M., Romero-Severson J., Vanzee J.P., Alvarez-Ponce D., Vieira F.G., Aguade M., Guirao-Rico S., Anzola J.M., Yoon K.S., Strycharz J.P., Unger M.F., Christley S., Lobo N.F., Seufferheld M.J., Wang N., Dasch G.A., Struchiner C.J., Madey G., Hannick L.I., Bidwell S., Joardar V., Caler E., Shao R., Barker S.C., Cameron S., Bruggner R.V., Regier A., Johnson J., Viswanathan L., Utterback T.R., Sutton G.G., Lawson D., Waterhouse R.M., Venter J.C., Strausberg R.L., Berenbaum M.R., Collins F.H., Zdobnov E.M., Pittendrigh B.R. Proc. Natl. Acad. Sci. U.S.A. 107:12168-12173(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: USDA.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DS235357 Genomic DNA. Translation: EEB15194.1.
RefSeq	XP_002427932.1. XM_002427887.1.
3D structure databases
ModBase	Search...
Protein family/group databases
MEROPS	S08.109.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	8232027.
KEGG	phu:Phum_PHUM354430.
VectorBase	PHUM354430. Pediculus humanus.
Organism-specific databases
CTD	8232027.
Phylogenomic databases
KO	K01360.
OMA	EYARNAY.
Family and domain databases
Gene3D	3.40.50.200. 1 hit.
InterPro	IPR008979. Galactose-bd-like. IPR000209. Peptidase_S8/S53_dom. IPR023827. Peptidase_S8_Asp-AS. IPR022398. Peptidase_S8_His-AS. IPR023828. Peptidase_S8_Ser-AS. IPR015500. Peptidase_S8_subtilisin-rel. IPR009020. Prot_inh_propept. IPR002884. PrprotnconvertsP. [Graphical view]
PANTHER	PTHR10795. PTHR10795. 1 hit.
Pfam	PF01483. P_proprotein. 1 hit. PF00082. Peptidase_S8. 1 hit. [Graphical view]
PRINTS	PR00723. SUBTILISIN.
SUPFAM	SSF49785. Gal_bind_like. 1 hit. SSF52743. Pept_S8_S53. 1 hit. SSF54897. Prot_inh_propept. 1 hit.
PROSITE	PS00136. SUBTILASE_ASP. 1 hit. PS00137. SUBTILASE_HIS. 1 hit. PS00138. SUBTILASE_SER. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

E0VP88_PEDHC

Accession

Primary (citable) accession number: E0VP88

Entry history

Integrated into UniProtKB/TrEMBL:	November 2, 2010
Last sequence update:	November 2, 2010
Last modified:	March 6, 2013
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)