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Protein

Catalase

Gene

Phum_PHUM336860

Organism
Pediculus humanus subsp. corporis (Body louse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.UniRule annotation

Catalytic activityi

2 H2O2 = O2 + 2 H2O.UniRule annotation

Cofactori

hemeUniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei72UniRule annotation1
Active sitei145UniRule annotation1
Metal bindingi355Iron (heme axial ligand)UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase, Peroxidase

Keywords - Biological processi

Hydrogen peroxideUniRule annotation

Keywords - Ligandi

HemeUniRule annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
CatalaseUniRule annotation (EC:1.11.1.6UniRule annotation)
Gene namesi
ORF Names:Phum_PHUM336860Imported
OrganismiPediculus humanus subsp. corporis (Body louse)Imported
Taxonomic identifieri121224 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraParaneopteraPhthirapteraAnopluraPediculidaePediculus
Proteomesi
  • UP000009046 Componenti: Partially assembled WGS sequence

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 410CatalaseInterPro annotationAdd BLAST386

Sequence similaritiesi

Belongs to the catalase family.UniRule annotation

Phylogenomic databases

InParanoidiE0VNL6.
KOiK03781.
OMAiWDYRADD.
PhylomeDBiE0VNL6.

Family and domain databases

Gene3Di2.40.180.10. 1 hit.
InterProiIPR018028. Catalase.
IPR020835. Catalase-like_dom.
IPR024708. Catalase_AS.
IPR024711. Catalase_clade1/3.
IPR011614. Catalase_core.
IPR002226. Catalase_haem_BS.
IPR010582. Catalase_immune_responsive.
[Graphical view]
PANTHERiPTHR11465. PTHR11465. 1 hit.
PfamiPF00199. Catalase. 1 hit.
PF06628. Catalase-rel. 1 hit.
[Graphical view]
PIRSFiPIRSF038928. Catalase_clade1-3. 1 hit.
PRINTSiPR00067. CATALASE.
SMARTiSM01060. Catalase. 1 hit.
[Graphical view]
SUPFAMiSSF56634. SSF56634. 1 hit.
PROSITEiPS00437. CATALASE_1. 1 hit.
PS00438. CATALASE_2. 1 hit.
PS51402. CATALASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E0VNL6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALRDPATEQ LSNYKKNHPK PEVLVTGHGA PIDDKLNSLS IGPRGPLLLQ
60 70 80 90 100
DVTYIDEIAH FDRERIPERV VHAKGAGAFG YFEVTHDIRK YCRASVFSEI
110 120 130 140 150
GKKTPVAVRF STVGGESGSA DTVRDPRGFA VKFYTDEGNW DLVGNNTPIF
160 170 180 190 200
FIRDPLLFPS FIHTQKRNPA THLKDPDMFW DFITLRPETT HQVMILFSDR
210 220 230 240 250
GIPDGYRHMN GYGSHTFKLV NDKYEAVYCK FHLKTDQGIK NCLPSKANQL
260 270 280 290 300
SADDPDYAIR DLYNAIENGQ YPSWSFYIQV MTFEQAERFK YNPFDLTKIW
310 320 330 340 350
PHSEYPLIPV GKLVLNRNPK NYFAEVEQIA FSPSHLVPGI EPSPDKMLQG
360 370 380 390 400
RLFSYADTHR HRLGANYLQL PVNCPYRTTV ANYQRDGPQN YGNNQDGAPN
410 420 430 440 450
YFPNSFNGPM DDKKQVQHVF KATGDVARYN SSNEDNFSQA NDLWSKVLND
460 470 480 490
EERERLVSNI ADHLKSASGF IQDRAIKNFS SVNAAMGHHF K
Length:491
Mass (Da):55,924
Last modified:November 2, 2010 - v1
Checksum:i6FB3B51CD89C4D95
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS235340 Genomic DNA. Translation: EEB14972.1.
RefSeqiXP_002427710.1. XM_002427665.1.

Genome annotation databases

EnsemblMetazoaiPHUM336860-RA; PHUM336860-PA; PHUM336860.
GeneIDi8231793.
KEGGiphu:Phum_PHUM336860.
VectorBaseiPHUM336860-RA; PHUM336860-PA; PHUM336860.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS235340 Genomic DNA. Translation: EEB14972.1.
RefSeqiXP_002427710.1. XM_002427665.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiPHUM336860-RA; PHUM336860-PA; PHUM336860.
GeneIDi8231793.
KEGGiphu:Phum_PHUM336860.
VectorBaseiPHUM336860-RA; PHUM336860-PA; PHUM336860.

Organism-specific databases

CTDi8231793.

Phylogenomic databases

InParanoidiE0VNL6.
KOiK03781.
OMAiWDYRADD.
PhylomeDBiE0VNL6.

Family and domain databases

Gene3Di2.40.180.10. 1 hit.
InterProiIPR018028. Catalase.
IPR020835. Catalase-like_dom.
IPR024708. Catalase_AS.
IPR024711. Catalase_clade1/3.
IPR011614. Catalase_core.
IPR002226. Catalase_haem_BS.
IPR010582. Catalase_immune_responsive.
[Graphical view]
PANTHERiPTHR11465. PTHR11465. 1 hit.
PfamiPF00199. Catalase. 1 hit.
PF06628. Catalase-rel. 1 hit.
[Graphical view]
PIRSFiPIRSF038928. Catalase_clade1-3. 1 hit.
PRINTSiPR00067. CATALASE.
SMARTiSM01060. Catalase. 1 hit.
[Graphical view]
SUPFAMiSSF56634. SSF56634. 1 hit.
PROSITEiPS00437. CATALASE_1. 1 hit.
PS00438. CATALASE_2. 1 hit.
PS51402. CATALASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiE0VNL6_PEDHC
AccessioniPrimary (citable) accession number: E0VNL6
Entry historyi
Integrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 2, 2010
Last modified: November 30, 2016
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.