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E0VNL6

- E0VNL6_PEDHC

UniProt

E0VNL6 - E0VNL6_PEDHC

Protein

Catalase

Gene

Phum_PHUM336860

Organism
Pediculus humanus subsp. corporis (Body louse)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 27 (01 Oct 2014)
      Sequence version 1 (02 Nov 2010)
      Previous versions | rss
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    Functioni

    Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.UniRule annotation

    Catalytic activityi

    2 H2O2 = O2 + 2 H2O.UniRule annotation

    Cofactori

    Heme group.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei72 – 721UniRule annotation
    Active sitei145 – 1451UniRule annotation
    Active sitei145 – 1451 By similarity
    Metal bindingi355 – 3551Iron (heme axial ligand)UniRule annotation

    GO - Molecular functioni

    1. catalase activity Source: UniProtKB-EC
    2. heme binding Source: InterPro
    3. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. hydrogen peroxide catabolic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Oxidoreductase, Peroxidase

    Keywords - Biological processi

    Hydrogen peroxideUniRule annotation

    Keywords - Ligandi

    HemeUniRule annotation, Iron, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    CatalaseUniRule annotation (EC:1.11.1.6UniRule annotation)
    Gene namesi
    ORF Names:Phum_PHUM336860Imported
    OrganismiPediculus humanus subsp. corporis (Body louse)Imported
    Taxonomic identifieri121224 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraParaneopteraPhthirapteraAnopluraPediculidaePediculus
    ProteomesiUP000009046: Partially assembled WGS sequence

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the catalase family.UniRule annotation

    Phylogenomic databases

    KOiK03781.
    OMAiNASQFIQ.
    OrthoDBiEOG7V7660.
    PhylomeDBiE0VNL6.

    Family and domain databases

    Gene3Di2.40.180.10. 1 hit.
    InterProiIPR018028. Catalase.
    IPR020835. Catalase-like_dom.
    IPR024708. Catalase_AS.
    IPR024711. Catalase_clade1/3.
    IPR011614. Catalase_core.
    IPR002226. Catalase_haem_BS.
    IPR010582. Catalase_immune_responsive.
    [Graphical view]
    PANTHERiPTHR11465. PTHR11465. 1 hit.
    PfamiPF00199. Catalase. 1 hit.
    PF06628. Catalase-rel. 1 hit.
    [Graphical view]
    PIRSFiPIRSF038928. Catalase_clade1-3. 1 hit.
    PRINTSiPR00067. CATALASE.
    SMARTiSM01060. Catalase. 1 hit.
    [Graphical view]
    SUPFAMiSSF56634. SSF56634. 1 hit.
    PROSITEiPS00437. CATALASE_1. 1 hit.
    PS00438. CATALASE_2. 1 hit.
    PS51402. CATALASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E0VNL6-1 [UniParc]FASTAAdd to Basket

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    MALRDPATEQ LSNYKKNHPK PEVLVTGHGA PIDDKLNSLS IGPRGPLLLQ    50
    DVTYIDEIAH FDRERIPERV VHAKGAGAFG YFEVTHDIRK YCRASVFSEI 100
    GKKTPVAVRF STVGGESGSA DTVRDPRGFA VKFYTDEGNW DLVGNNTPIF 150
    FIRDPLLFPS FIHTQKRNPA THLKDPDMFW DFITLRPETT HQVMILFSDR 200
    GIPDGYRHMN GYGSHTFKLV NDKYEAVYCK FHLKTDQGIK NCLPSKANQL 250
    SADDPDYAIR DLYNAIENGQ YPSWSFYIQV MTFEQAERFK YNPFDLTKIW 300
    PHSEYPLIPV GKLVLNRNPK NYFAEVEQIA FSPSHLVPGI EPSPDKMLQG 350
    RLFSYADTHR HRLGANYLQL PVNCPYRTTV ANYQRDGPQN YGNNQDGAPN 400
    YFPNSFNGPM DDKKQVQHVF KATGDVARYN SSNEDNFSQA NDLWSKVLND 450
    EERERLVSNI ADHLKSASGF IQDRAIKNFS SVNAAMGHHF K 491
    Length:491
    Mass (Da):55,924
    Last modified:November 2, 2010 - v1
    Checksum:i6FB3B51CD89C4D95
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS235340 Genomic DNA. Translation: EEB14972.1.
    RefSeqiXP_002427710.1. XM_002427665.1.

    Genome annotation databases

    GeneIDi8231793.
    KEGGiphu:Phum_PHUM336860.
    VectorBaseiPHUM336860. Pediculus humanus.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS235340 Genomic DNA. Translation: EEB14972.1 .
    RefSeqi XP_002427710.1. XM_002427665.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 8231793.
    KEGGi phu:Phum_PHUM336860.
    VectorBasei PHUM336860. Pediculus humanus.

    Organism-specific databases

    CTDi 8231793.

    Phylogenomic databases

    KOi K03781.
    OMAi NASQFIQ.
    OrthoDBi EOG7V7660.
    PhylomeDBi E0VNL6.

    Family and domain databases

    Gene3Di 2.40.180.10. 1 hit.
    InterProi IPR018028. Catalase.
    IPR020835. Catalase-like_dom.
    IPR024708. Catalase_AS.
    IPR024711. Catalase_clade1/3.
    IPR011614. Catalase_core.
    IPR002226. Catalase_haem_BS.
    IPR010582. Catalase_immune_responsive.
    [Graphical view ]
    PANTHERi PTHR11465. PTHR11465. 1 hit.
    Pfami PF00199. Catalase. 1 hit.
    PF06628. Catalase-rel. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF038928. Catalase_clade1-3. 1 hit.
    PRINTSi PR00067. CATALASE.
    SMARTi SM01060. Catalase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56634. SSF56634. 1 hit.
    PROSITEi PS00437. CATALASE_1. 1 hit.
    PS00438. CATALASE_2. 1 hit.
    PS51402. CATALASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequences of the human body louse and its primary endosymbiont provide insights into the permanent parasitic lifestyle."
      Kirkness E.F., Haas B.J., Sun W., Braig H.R., Perotti M.A., Clark J.M., Lee S.H., Robertson H.M., Kennedy R.C., Elhaik E., Gerlach D., Kriventseva E.V., Elsik C.G., Graur D., Hill C.A., Veenstra J.A., Walenz B., Tubio J.M.
      , Ribeiro J.M., Rozas J., Johnston J.S., Reese J.T., Popadic A., Tojo M., Raoult D., Reed D.L., Tomoyasu Y., Krause E., Mittapalli O., Margam V.M., Li H.M., Meyer J.M., Johnson R.M., Romero-Severson J., Vanzee J.P., Alvarez-Ponce D., Vieira F.G., Aguade M., Guirao-Rico S., Anzola J.M., Yoon K.S., Strycharz J.P., Unger M.F., Christley S., Lobo N.F., Seufferheld M.J., Wang N., Dasch G.A., Struchiner C.J., Madey G., Hannick L.I., Bidwell S., Joardar V., Caler E., Shao R., Barker S.C., Cameron S., Bruggner R.V., Regier A., Johnson J., Viswanathan L., Utterback T.R., Sutton G.G., Lawson D., Waterhouse R.M., Venter J.C., Strausberg R.L., Berenbaum M.R., Collins F.H., Zdobnov E.M., Pittendrigh B.R.
      Proc. Natl. Acad. Sci. U.S.A. 107:12168-12173(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: USDAImported.

    Entry informationi

    Entry nameiE0VNL6_PEDHC
    AccessioniPrimary (citable) accession number: E0VNL6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 2, 2010
    Last sequence update: November 2, 2010
    Last modified: October 1, 2014
    This is version 27 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3