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Protein
Submitted name:

Furin-1, putative

Gene

Phum_PHUM246240

Organism
Pediculus humanus subsp. corporis (Body louse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protease, Serine proteaseSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Furin-1, putativeImported (EC:3.4.21.93Imported)
Gene namesi
ORF Names:Phum_PHUM246240Imported
OrganismiPediculus humanus subsp. corporis (Body louse)Imported
Taxonomic identifieri121224 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraParaneopteraPhthirapteraAnopluraPediculidaePediculus
Proteomesi
  • UP000009046 Componenti: Partially assembled WGS sequence

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2121Sequence analysisAdd
BLAST
Chaini22 – 678657Sequence analysisPRO_5003141824Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliE0VJJ3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini34 – 11077S8_pro-domainInterPro annotationAdd
BLAST
Domaini204 – 488285Peptidase S8InterPro annotationAdd
BLAST
Domaini543 – 62280P_proproteinInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the peptidase S8 family.SAAS annotation
Contains peptidase S8 domain.SAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

InParanoidiE0VJJ3.
KOiK01359.
OMAiGVKQGRQ.
PhylomeDBiE0VJJ3.

Family and domain databases

Gene3Di2.60.120.260. 1 hit.
3.30.70.850. 1 hit.
3.40.50.200. 1 hit.
InterProiIPR008979. Galactose-bd-like.
IPR000209. Peptidase_S8/S53_dom.
IPR022398. Peptidase_S8_His-AS.
IPR023828. Peptidase_S8_Ser-AS.
IPR015500. Peptidase_S8_subtilisin-rel.
IPR009020. Propept_inh.
IPR002884. PrprotnconvertsP.
IPR032815. S8_pro-domain.
[Graphical view]
PANTHERiPTHR10795. PTHR10795. 2 hits.
PfamiPF01483. P_proprotein. 1 hit.
PF00082. Peptidase_S8. 1 hit.
PF16470. S8_pro-domain. 1 hit.
[Graphical view]
PRINTSiPR00723. SUBTILISIN.
SUPFAMiSSF49785. SSF49785. 1 hit.
SSF52743. SSF52743. 1 hit.
SSF54897. SSF54897. 1 hit.
PROSITEiPS00137. SUBTILASE_HIS. 1 hit.
PS00138. SUBTILASE_SER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E0VJJ3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVKFFWSFIT IFLILKFTIS AHNGEEHTKY YSNEWVIRLE GGQDVAELIS
60 70 80 90 100
AKLGYKLLGK VTGFNDTYRI IKEDIFIQKK RNHALLTETL EKDSRVIWAE
110 120 130 140 150
QQFTKERVKR GFLYDNSLST VYNENNEKLT RQSILNLLKE KNISYNQEKI
160 170 180 190 200
LFRPSDVSMR YASYDRFNDE LWNQQWYLQD TRTQSNLPKL DLHVLPVYDL
210 220 230 240 250
GITGKGVRVL ILDDGIEYTH EDLWENYDPE ISYDANDEDD DPFPRLDEEG
260 270 280 290 300
SNAHGTRCAG EVAMKANNLK CGVGVAFNAR VGALRLLDGE VNDRIEGIAL
310 320 330 340 350
GYAYDKVDIY SASWGPTDDG KTVEGPGRLA KEAIERGVTE GRNGKGVIYV
360 370 380 390 400
WAGGNGGSKD DNCDCDGYIG SIYTLSIGSA SQHGQFPWYG EKCAATMAAT
410 420 430 440 450
YSSGAYADQM IATTDVGNTC TIKHTGTSAS APLAAGIIAL ALEANSDLTW
460 470 480 490 500
RDIQHLVAWT SEYSPLSENE GWVMNAAGFW VNTRFGFGLM NAYSLVAAAI
510 520 530 540 550
NWTNVPEKYS CSIEAGKKSE EIYWGKDVNL EINATVCDYV YYLEHVELEI
560 570 580 590 600
NIEYPVRGNL EIFLESPSGT NIQLLGRRKN DSSKRGFKNW KLMSVLTWNE
610 620 630 640 650
NPRGIWKVTV TDKIGTAKQK GRTGKFILHL HGLYDRPKYL ENQNLNTDNN
660 670
KMNKKNELNT IDIDDKYFGC KFLQKWMP
Length:678
Mass (Da):76,706
Last modified:November 2, 2010 - v1
Checksum:iE89BB72505F17D0D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS235222 Genomic DNA. Translation: EEB13549.1.
RefSeqiXP_002426287.1. XM_002426242.1.

Genome annotation databases

EnsemblMetazoaiPHUM246240-RA; PHUM246240-PA; PHUM246240.
GeneIDi8230822.
KEGGiphu:Phum_PHUM246240.
VectorBaseiPHUM246240-RA; PHUM246240-PA; PHUM246240.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS235222 Genomic DNA. Translation: EEB13549.1.
RefSeqiXP_002426287.1. XM_002426242.1.

3D structure databases

ProteinModelPortaliE0VJJ3.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiPHUM246240-RA; PHUM246240-PA; PHUM246240.
GeneIDi8230822.
KEGGiphu:Phum_PHUM246240.
VectorBaseiPHUM246240-RA; PHUM246240-PA; PHUM246240.

Organism-specific databases

CTDi8230822.

Phylogenomic databases

InParanoidiE0VJJ3.
KOiK01359.
OMAiGVKQGRQ.
PhylomeDBiE0VJJ3.

Family and domain databases

Gene3Di2.60.120.260. 1 hit.
3.30.70.850. 1 hit.
3.40.50.200. 1 hit.
InterProiIPR008979. Galactose-bd-like.
IPR000209. Peptidase_S8/S53_dom.
IPR022398. Peptidase_S8_His-AS.
IPR023828. Peptidase_S8_Ser-AS.
IPR015500. Peptidase_S8_subtilisin-rel.
IPR009020. Propept_inh.
IPR002884. PrprotnconvertsP.
IPR032815. S8_pro-domain.
[Graphical view]
PANTHERiPTHR10795. PTHR10795. 2 hits.
PfamiPF01483. P_proprotein. 1 hit.
PF00082. Peptidase_S8. 1 hit.
PF16470. S8_pro-domain. 1 hit.
[Graphical view]
PRINTSiPR00723. SUBTILISIN.
SUPFAMiSSF49785. SSF49785. 1 hit.
SSF52743. SSF52743. 1 hit.
SSF54897. SSF54897. 1 hit.
PROSITEiPS00137. SUBTILASE_HIS. 1 hit.
PS00138. SUBTILASE_SER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiE0VJJ3_PEDHC
AccessioniPrimary (citable) accession number: E0VJJ3
Entry historyi
Integrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 2, 2010
Last modified: September 7, 2016
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.