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Protein
Submitted name:

Furin-1 precursor, putative

Gene

8230822

Organism
Pediculus humanus subsp. corporis (Body louse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protease, Serine proteaseSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Furin-1 precursor, putativeImported
Submitted name:
Furin-1, putativeImported (EC:3.4.21.93Imported)
Gene namesi
Name:8230822Imported
ORF Names:Phum_PHUM246240Imported
OrganismiPediculus humanus subsp. corporis (Body louse)Imported
Taxonomic identifieri121224 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraParaneopteraPsocodeaPhthirapteraAnopluraPediculidaePediculus
Proteomesi
  • UP000009046 Componenti: Partially assembled WGS sequence

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_501083023922 – 678Sequence analysisAdd BLAST657

Interactioni

Protein-protein interaction databases

STRINGi121225.PHUM246240-PA.

Structurei

3D structure databases

ProteinModelPortaliE0VJJ3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini34 – 110S8_pro-domainInterPro annotationAdd BLAST77
Domaini204 – 488Peptidase S8InterPro annotationAdd BLAST285
Domaini543 – 622P_proproteinInterPro annotationAdd BLAST80

Sequence similaritiesi

Belongs to the peptidase S8 family.SAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

InParanoidiE0VJJ3.
KOiK01359.
OMAiFEPRALK.
PhylomeDBiE0VJJ3.

Family and domain databases

CDDicd04059. Peptidases_S8_Protein_converta. 1 hit.
Gene3Di2.60.120.260. 1 hit.
3.40.50.200. 1 hit.
InterProiView protein in InterPro
IPR008979. Galactose-bd-like.
IPR034182. Kexin/furin.
IPR009020. Peptidase/Inhibitor_I9.
IPR000209. Peptidase_S8/S53_dom.
IPR022398. Peptidase_S8_His-AS.
IPR023828. Peptidase_S8_Ser-AS.
IPR015500. Peptidase_S8_subtilisin-rel.
IPR002884. PrprotnconvertsP.
IPR032815. S8_pro-domain.
PfamiView protein in Pfam
PF01483. P_proprotein. 1 hit.
PF00082. Peptidase_S8. 1 hit.
PF16470. S8_pro-domain. 1 hit.
PRINTSiPR00723. SUBTILISIN.
SUPFAMiSSF49785. SSF49785. 1 hit.
SSF52743. SSF52743. 1 hit.
SSF54897. SSF54897. 1 hit.
PROSITEiView protein in PROSITE
PS00137. SUBTILASE_HIS. 1 hit.
PS00138. SUBTILASE_SER. 1 hit.

Sequencei

Sequence statusi: Complete.

E0VJJ3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVKFFWSFIT IFLILKFTIS AHNGEEHTKY YSNEWVIRLE GGQDVAELIS
60 70 80 90 100
AKLGYKLLGK VTGFNDTYRI IKEDIFIQKK RNHALLTETL EKDSRVIWAE
110 120 130 140 150
QQFTKERVKR GFLYDNSLST VYNENNEKLT RQSILNLLKE KNISYNQEKI
160 170 180 190 200
LFRPSDVSMR YASYDRFNDE LWNQQWYLQD TRTQSNLPKL DLHVLPVYDL
210 220 230 240 250
GITGKGVRVL ILDDGIEYTH EDLWENYDPE ISYDANDEDD DPFPRLDEEG
260 270 280 290 300
SNAHGTRCAG EVAMKANNLK CGVGVAFNAR VGALRLLDGE VNDRIEGIAL
310 320 330 340 350
GYAYDKVDIY SASWGPTDDG KTVEGPGRLA KEAIERGVTE GRNGKGVIYV
360 370 380 390 400
WAGGNGGSKD DNCDCDGYIG SIYTLSIGSA SQHGQFPWYG EKCAATMAAT
410 420 430 440 450
YSSGAYADQM IATTDVGNTC TIKHTGTSAS APLAAGIIAL ALEANSDLTW
460 470 480 490 500
RDIQHLVAWT SEYSPLSENE GWVMNAAGFW VNTRFGFGLM NAYSLVAAAI
510 520 530 540 550
NWTNVPEKYS CSIEAGKKSE EIYWGKDVNL EINATVCDYV YYLEHVELEI
560 570 580 590 600
NIEYPVRGNL EIFLESPSGT NIQLLGRRKN DSSKRGFKNW KLMSVLTWNE
610 620 630 640 650
NPRGIWKVTV TDKIGTAKQK GRTGKFILHL HGLYDRPKYL ENQNLNTDNN
660 670
KMNKKNELNT IDIDDKYFGC KFLQKWMP
Length:678
Mass (Da):76,706
Last modified:November 2, 2010 - v1
Checksum:iE89BB72505F17D0D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS235222 Genomic DNA. Translation: EEB13549.1.
RefSeqiXP_002426287.1. XM_002426242.1.

Genome annotation databases

EnsemblMetazoaiPHUM246240-RA; PHUM246240-PA; PHUM246240.
GeneIDi8230822.
KEGGiphu:Phum_PHUM246240.
VectorBaseiPHUM246240-RA; PHUM246240-PA; PHUM246240.

Similar proteinsi

Entry informationi

Entry nameiE0VJJ3_PEDHC
AccessioniPrimary (citable) accession number: E0VJJ3
Entry historyiIntegrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 2, 2010
Last modified: August 30, 2017
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported