E0VJG1 (E0VJG1_PEDHC) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Protein MLP1, putative EMBL EEB13517.1
EC=2.1.1.43 EMBL EEB13517.1

Gene names

ORF Names:

Phum_PHUM244720 EMBL EEB13517.1

Organism

Pediculus humanus subsp. corporis (Body louse) [Reference proteome]

Taxonomic identifier

121224 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Paraneoptera › Phthiraptera › Anoplura › Pediculidae › Pediculus › Pediculus humanus

Protein attributes

Sequence length	2688 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity	S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone]. SAAS SAAS001214
Sequence similarities	Contains 1 SET domain. RuleBase RU004538 Contains 1 post-SET domain. SAAS SAAS001214 RuleBase RU004541

Ontologies

Keywords
Domain	Zinc-finger SAAS SAAS001965
Ligand	Metal-binding Zinc
Molecular function	Methyltransferase SAAS SAAS001214 RuleBase RU004541 EMBL EEB13517.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	histone lysine methylation Inferred from electronic annotation. Source: GOC
Cellular_component	nucleus Inferred from electronic annotation. Source: InterPro
Molecular_function	DNA binding Inferred from electronic annotation. Source: InterPro histone-lysine N-methyltransferase activity Inferred from electronic annotation. Source: EC zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E0VJG1 [UniParc]. Last modified November 2, 2010. Version 1. Checksum: B999A46F4626BEFE	FASTA	2,688	306,122
	10 20 30 40 50 60 MPHNKGGPCV RSDILASTAW NALIHHPVED SDAEELPSTV DIDAIKGAPI TGHTGHWNSL 70 80 90 100 110 120 NSNITKSNVE EKNESDSDDD KKISDSNSRS SSDSQSEDSE SGSCSWSSSS ESSSRSSSCS 130 140 150 160 170 180 SQSAVQSRIS SPPSQTFSIR ESNFEQSSSR SQTGTESDSC SSMKHEKFKL GQLYMDEKEK 190 200 210 220 230 240 MKKPTKVKSR LRFSGINDAK KKLHVDQGVD NKSLKETSMS SLKLTTSVTQ ISSTKKINKN 250 260 270 280 290 300 GESKSSVNVK SKNDNLKTFN CNKTEETSKS ISMCEGPIIV GNKLNDSKSL SKKFNGKSII 310 320 330 340 350 360 NKKLDSSTIK RDLDINKCCS IVMPSNKKLS EASKLRCVRK NTGSQYNKPQ SAIKPEAYSE 370 380 390 400 410 420 SSESENDCSK DEAAHYTALA QQLSHIGNSE TLSSMSEHLQ VINQEDLAAI LPDVVTAENH 430 440 450 460 470 480 GSFDGFEDVS LECGKNEKKN VNQDSGSDVE LPDQIVNDAI KRIHIDSEEM ENSESEKGNQ 490 500 510 520 530 540 SSSDEDVEFR RGYSSSLLQQ FVEKTEILSA QCERLINVSR SRKIASQNSL LMENILERRI 550 560 570 580 590 600 KRGRPPKIVK NSTSNNVESA QVVLGSVDRT NNKLMPELEA YRLDSSLSNV SPDSGIQSVP 610 620 630 640 650 660 GSPVNENIHV SPCRDVTPPI LRPVTPVTGI PNKLSYLTKK SDISKKRPGR PKKIKLEVFR 670 680 690 700 710 720 NLLQNNNQSE TKKDKNVKSE DRPPIHSLIP ERRGPGRPKK APPILEPNIP MVCRNELCKK 730 740 750 760 770 780 ETRNNINIVL NEICERVSRQ LDFPSLSKES MRNVELNKED IERILLHHKS KKSRNLKFDA 790 800 810 820 830 840 IFSKSMRLSN PPNVAIVKPM QHHRVEDNNV ENDKLNKKSG KKCKNGNLDE NTWYSVKLAC 850 860 870 880 890 900 EKLNIAEKEK DFTDKKSRSF MDEKLNKGNK CKKKTEGKSK TKDLGHKSVG FVSTPRTFPT 910 920 930 940 950 960 YKTLSTNDQL SKYFEKAKPN LQKKIHSLKK PRKNLKKSIK RKNGKTIHNL LHRKHKKCKR 970 980 990 1000 1010 1020 SMKHLKCKQK KLDNEWFFKE LEELITEFQK FSIGIVKKSI SLVTGNNLCT MQTVNSVQNE 1030 1040 1050 1060 1070 1080 MGLPADFRVK RAVKKRKGSE KSRGSDRESG AEKSKLSDRE SGPELPENEV LREKPKRKQK 1090 1100 1110 1120 1130 1140 KNHVEVINQG ADTNSNEQRL PLKKRHYHLT SASNQQLLPS WTSDSTQSIV KSINADKPIN 1150 1160 1170 1180 1190 1200 KEVNSHLKKE AVEKIKCADS QKIQRNSIDE AIEATITRYT TKSCNVSPET NSDSNSTQSQ 1210 1220 1230 1240 1250 1260 FNNQQCVITT PKKRHRVPDL VAKTVFQSNI CKNNNDVKSI LKNSDINVKT MLSLRHGAGN 1270 1280 1290 1300 1310 1320 YTKVEPSCVQ NLIKTSNFIK ETNNKLFLPI ESKKKTGIKN ISKDIKGDKY VTGSTKGDIE 1330 1340 1350 1360 1370 1380 KSDNDEIFTR NNDKIKKYGL KNSEHSEHLH FSKTSEERLK KYEFKNVLFE KTLSKTSQKQ 1390 1400 1410 1420 1430 1440 HYTRSSSKTD MTPSDQTQSN NSKEVHLCKF NGSKESNEND HDDDKISEKL PEIEIFDSSL 1450 1460 1470 1480 1490 1500 DAKYDGKTLS PTVNLQNEND KNSSNLKKYR DGRILQSVEE KRKDKSHKKL FTQKKGIRKS 1510 1520 1530 1540 1550 1560 NYFKKPRCLK SCKEVRVNVK ESTPKDILIT KGVVEKKKVK RRKAINRTGF PSNKKKKKKM 1570 1580 1590 1600 1610 1620 SIKLDEIEDK TASEMTKFSN PDGSATKLQE CETDKFSEDS NNKKNNLNLS TNTTDLNKSL 1630 1640 1650 1660 1670 1680 DCPTNESVKT DDDENNLENN RGNQISLEET TVQDSITEER ESKVEGKVSE SSGTKRVRKN 1690 1700 1710 1720 1730 1740 SSSLSDLVAK KVKTIKTENE EPKVKNNADL HKGIETTTGT ISTRKRKSLN TTKNINFGLN 1750 1760 1770 1780 1790 1800 RYQYPLLSMK KFKRAKEELR AQSEESICDS VEEEVSKIKK SHPRWRKKYL AAGLFSDFYK 1810 1820 1830 1840 1850 1860 QDPPQKVNKV NEKSLSKLVY LLADQELDLL PPPSYCNKYV RLRRVDYQLP FDLWWLHTHS 1870 1880 1890 1900 1910 1920 QLPGRDIVPS WNYKKIRTNI YYDVKPQMTG TYEAQACNCT VPLNTKQKGC GEECINRMVF 1930 1940 1950 1960 1970 1980 AECSPQLCPC KEKCSNQRIQ KHEFAPGLQK FMTKNKGWGI RTKQPIKAGD FILEYVGEVV 1990 2000 2010 2020 2030 2040 SDKEFKDRMA SIYVNDKHHY CLHLDGGLVI DGHRMGGDGR FVNHSCNPNC EMQKWSVNGL 2050 2060 2070 2080 2090 2100 FRMALFALRN IPAHQELTYD YNFSLFNPAE GQPCYCGTNE CRGVIGGKSQ RIPLGNGQNV 2110 2120 2130 2140 2150 2160 VTSEKKEKKM VGRPRKTGKA KKHNVRDKNK IETVTVKPST KPMSHQQRCF VQMHHCFLLR 2170 2180 2190 2200 2210 2220 NVDKVKRNKN NSKWNWKQSN NEVQSFSRQL PEIKQSDVFY TQLNALSTLR SIKTRRLAQA 2230 2240 2250 2260 2270 2280 EDNPELTKVA KLAYIFKDLY SAVISAKDEK GELLSAPFTN LPPKRKLPAY YQRVSDPIDL 2290 2300 2310 2320 2330 2340 ITIEQNINTG NYKTIEAFDQ DMTKLFNNNV KFYGRTSELG IASTRLRRVY CLAKYDSASE 2350 2360 2370 2380 2390 2400 LEKVLGDAIP SSFIPENANP GDEEEDVIRC ICGLYKDEGV MIQCERCLVW QHCDCVKADD 2410 2420 2430 2440 2450 2460 SVEHYLCERC DPREVNLEIL IDPQPEYATE DTTHYISLLR GDLQLRIGDA VYVLRDMIEE 2470 2480 2490 2500 2510 2520 NTPKTSPPTK VTYKTIQNVN YADLDIFRIE RLWIDKKGDK FAFGHHYLRP HETYHEPTRK 2530 2540 2550 2560 2570 2580 FFHNEVMRVP LYEVVPLDLI MNHCWVLDLN TYCKGRPIGA PEEHIYICEY RVDKSAHLFA 2590 2600 2610 2620 2630 2640 KIAKPYLICT KTYAFEKFDV RLKPTRTYTV HEAKSESLKQ SESDEELPLA KIKENVHAAK 2650 2660 2670 2680 RDEQKKRLNS ILLKLLSRLP NKQPLDLSYL LEPVKRFRGK AQQQGKRT

References

[1]

"Genome sequences of the human body louse and its primary endosymbiont provide insights into the permanent parasitic lifestyle." Kirkness E.F., Haas B.J., Sun W., Braig H.R., Perotti M.A., Clark J.M., Lee S.H., Robertson H.M., Kennedy R.C., Elhaik E., Gerlach D., Kriventseva E.V., Elsik C.G., Graur D., Hill C.A., Veenstra J.A., Walenz B., Tubio J.M. , Ribeiro J.M., Rozas J., Johnston J.S., Reese J.T., Popadic A., Tojo M., Raoult D., Reed D.L., Tomoyasu Y., Krause E., Mittapalli O., Margam V.M., Li H.M., Meyer J.M., Johnson R.M., Romero-Severson J., Vanzee J.P., Alvarez-Ponce D., Vieira F.G., Aguade M., Guirao-Rico S., Anzola J.M., Yoon K.S., Strycharz J.P., Unger M.F., Christley S., Lobo N.F., Seufferheld M.J., Wang N., Dasch G.A., Struchiner C.J., Madey G., Hannick L.I., Bidwell S., Joardar V., Caler E., Shao R., Barker S.C., Cameron S., Bruggner R.V., Regier A., Johnson J., Viswanathan L., Utterback T.R., Sutton G.G., Lawson D., Waterhouse R.M., Venter J.C., Strausberg R.L., Berenbaum M.R., Collins F.H., Zdobnov E.M., Pittendrigh B.R. Proc. Natl. Acad. Sci. U.S.A. 107:12168-12173(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: USDA.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DS235222 Genomic DNA. Translation: EEB13517.1.
RefSeq	XP_002426255.1. XM_002426210.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	8230790.
KEGG	phu:Phum_PHUM244720.
VectorBase	PHUM244720. Pediculus humanus.
Organism-specific databases
CTD	8230790.
Phylogenomic databases
KO	K06101.
Family and domain databases
Gene3D	1.20.920.10. 1 hit. 3.30.40.10. 1 hit.
InterPro	IPR017956. AT_hook_DNA-bd_motif. IPR006560. AWS. IPR001025. BAH_dom. IPR001487. Bromodomain. IPR003616. Post-SET_dom. IPR001214. SET_dom. IPR019786. Zinc_finger_PHD-type_CS. IPR011011. Znf_FYVE_PHD. IPR001965. Znf_PHD. IPR013083. Znf_RING/FYVE/PHD. [Graphical view]
Pfam	PF01426. BAH. 1 hit. PF00439. Bromodomain. 1 hit. PF00856. SET. 1 hit. [Graphical view]
SMART	SM00384. AT_hook. 4 hits. SM00570. AWS. 1 hit. SM00439. BAH. 1 hit. SM00297. BROMO. 1 hit. SM00249. PHD. 1 hit. SM00508. PostSET. 1 hit. SM00317. SET. 1 hit. [Graphical view]
SUPFAM	SSF47370. Bromodomain. 1 hit. SSF57903. FYVE_PHD_ZnF. 1 hit.
PROSITE	PS51215. AWS. 1 hit. PS51038. BAH. 1 hit. PS50014. BROMODOMAIN_2. 1 hit. PS50868. POST_SET. 1 hit. PS50280. SET. 1 hit. PS01359. ZF_PHD_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

E0VJG1_PEDHC

Accession

Primary (citable) accession number: E0VJG1

Entry history

Integrated into UniProtKB/TrEMBL:	November 2, 2010
Last sequence update:	November 2, 2010
Last modified:	April 3, 2013
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)