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E0VJG1

- E0VJG1_PEDHC

UniProt

E0VJG1 - E0VJG1_PEDHC

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Protein
Submitted name: Protein MLP1, putative
Gene
Phum_PHUM244720
Organism
Pediculus humanus subsp. corporis (Body louse)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].SAAS annotations

GO - Molecular functioni

  1. DNA binding Source: InterPro
  2. chromatin binding Source: InterPro
  3. histone-lysine N-methyltransferase activity Source: UniProtKB-EC
  4. zinc ion binding Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotationImported, Transferase

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Protein MLP1, putativeImported (EC:2.1.1.43Imported)
Gene namesi
ORF Names:Phum_PHUM244720Imported
OrganismiPediculus humanus subsp. corporis (Body louse)
Taxonomic identifieri121224 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraParaneopteraPhthirapteraAnopluraPediculidaePediculus
ProteomesiUP000009046: Partially assembled WGS sequence

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: InterPro
Complete GO annotation...

Family & Domainsi

Sequence similaritiesi

Contains 1 SET domain.UniRule annotation
Contains SET domain.SAAS annotations
Contains post-SET domain.SAAS annotations

Keywords - Domaini

Zinc-fingerSAAS annotations

Phylogenomic databases

KOiK06101.
OrthoDBiEOG7ZPNJ4.

Family and domain databases

Gene3Di1.20.920.10. 1 hit.
3.30.40.10. 1 hit.
InterProiIPR017956. AT_hook_DNA-bd_motif.
IPR006560. AWS.
IPR001025. BAH_dom.
IPR001487. Bromodomain.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
IPR019786. Zinc_finger_PHD-type_CS.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamiPF01426. BAH. 1 hit.
PF00439. Bromodomain. 1 hit.
PF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00384. AT_hook. 4 hits.
SM00570. AWS. 1 hit.
SM00439. BAH. 1 hit.
SM00297. BROMO. 1 hit.
SM00249. PHD. 1 hit.
SM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
SUPFAMiSSF47370. SSF47370. 1 hit.
SSF57903. SSF57903. 1 hit.
PROSITEiPS51215. AWS. 1 hit.
PS51038. BAH. 1 hit.
PS50014. BROMODOMAIN_2. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
PS01359. ZF_PHD_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E0VJG1-1 [UniParc]FASTAAdd to Basket

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MPHNKGGPCV RSDILASTAW NALIHHPVED SDAEELPSTV DIDAIKGAPI     50
TGHTGHWNSL NSNITKSNVE EKNESDSDDD KKISDSNSRS SSDSQSEDSE 100
SGSCSWSSSS ESSSRSSSCS SQSAVQSRIS SPPSQTFSIR ESNFEQSSSR 150
SQTGTESDSC SSMKHEKFKL GQLYMDEKEK MKKPTKVKSR LRFSGINDAK 200
KKLHVDQGVD NKSLKETSMS SLKLTTSVTQ ISSTKKINKN GESKSSVNVK 250
SKNDNLKTFN CNKTEETSKS ISMCEGPIIV GNKLNDSKSL SKKFNGKSII 300
NKKLDSSTIK RDLDINKCCS IVMPSNKKLS EASKLRCVRK NTGSQYNKPQ 350
SAIKPEAYSE SSESENDCSK DEAAHYTALA QQLSHIGNSE TLSSMSEHLQ 400
VINQEDLAAI LPDVVTAENH GSFDGFEDVS LECGKNEKKN VNQDSGSDVE 450
LPDQIVNDAI KRIHIDSEEM ENSESEKGNQ SSSDEDVEFR RGYSSSLLQQ 500
FVEKTEILSA QCERLINVSR SRKIASQNSL LMENILERRI KRGRPPKIVK 550
NSTSNNVESA QVVLGSVDRT NNKLMPELEA YRLDSSLSNV SPDSGIQSVP 600
GSPVNENIHV SPCRDVTPPI LRPVTPVTGI PNKLSYLTKK SDISKKRPGR 650
PKKIKLEVFR NLLQNNNQSE TKKDKNVKSE DRPPIHSLIP ERRGPGRPKK 700
APPILEPNIP MVCRNELCKK ETRNNINIVL NEICERVSRQ LDFPSLSKES 750
MRNVELNKED IERILLHHKS KKSRNLKFDA IFSKSMRLSN PPNVAIVKPM 800
QHHRVEDNNV ENDKLNKKSG KKCKNGNLDE NTWYSVKLAC EKLNIAEKEK 850
DFTDKKSRSF MDEKLNKGNK CKKKTEGKSK TKDLGHKSVG FVSTPRTFPT 900
YKTLSTNDQL SKYFEKAKPN LQKKIHSLKK PRKNLKKSIK RKNGKTIHNL 950
LHRKHKKCKR SMKHLKCKQK KLDNEWFFKE LEELITEFQK FSIGIVKKSI 1000
SLVTGNNLCT MQTVNSVQNE MGLPADFRVK RAVKKRKGSE KSRGSDRESG 1050
AEKSKLSDRE SGPELPENEV LREKPKRKQK KNHVEVINQG ADTNSNEQRL 1100
PLKKRHYHLT SASNQQLLPS WTSDSTQSIV KSINADKPIN KEVNSHLKKE 1150
AVEKIKCADS QKIQRNSIDE AIEATITRYT TKSCNVSPET NSDSNSTQSQ 1200
FNNQQCVITT PKKRHRVPDL VAKTVFQSNI CKNNNDVKSI LKNSDINVKT 1250
MLSLRHGAGN YTKVEPSCVQ NLIKTSNFIK ETNNKLFLPI ESKKKTGIKN 1300
ISKDIKGDKY VTGSTKGDIE KSDNDEIFTR NNDKIKKYGL KNSEHSEHLH 1350
FSKTSEERLK KYEFKNVLFE KTLSKTSQKQ HYTRSSSKTD MTPSDQTQSN 1400
NSKEVHLCKF NGSKESNEND HDDDKISEKL PEIEIFDSSL DAKYDGKTLS 1450
PTVNLQNEND KNSSNLKKYR DGRILQSVEE KRKDKSHKKL FTQKKGIRKS 1500
NYFKKPRCLK SCKEVRVNVK ESTPKDILIT KGVVEKKKVK RRKAINRTGF 1550
PSNKKKKKKM SIKLDEIEDK TASEMTKFSN PDGSATKLQE CETDKFSEDS 1600
NNKKNNLNLS TNTTDLNKSL DCPTNESVKT DDDENNLENN RGNQISLEET 1650
TVQDSITEER ESKVEGKVSE SSGTKRVRKN SSSLSDLVAK KVKTIKTENE 1700
EPKVKNNADL HKGIETTTGT ISTRKRKSLN TTKNINFGLN RYQYPLLSMK 1750
KFKRAKEELR AQSEESICDS VEEEVSKIKK SHPRWRKKYL AAGLFSDFYK 1800
QDPPQKVNKV NEKSLSKLVY LLADQELDLL PPPSYCNKYV RLRRVDYQLP 1850
FDLWWLHTHS QLPGRDIVPS WNYKKIRTNI YYDVKPQMTG TYEAQACNCT 1900
VPLNTKQKGC GEECINRMVF AECSPQLCPC KEKCSNQRIQ KHEFAPGLQK 1950
FMTKNKGWGI RTKQPIKAGD FILEYVGEVV SDKEFKDRMA SIYVNDKHHY 2000
CLHLDGGLVI DGHRMGGDGR FVNHSCNPNC EMQKWSVNGL FRMALFALRN 2050
IPAHQELTYD YNFSLFNPAE GQPCYCGTNE CRGVIGGKSQ RIPLGNGQNV 2100
VTSEKKEKKM VGRPRKTGKA KKHNVRDKNK IETVTVKPST KPMSHQQRCF 2150
VQMHHCFLLR NVDKVKRNKN NSKWNWKQSN NEVQSFSRQL PEIKQSDVFY 2200
TQLNALSTLR SIKTRRLAQA EDNPELTKVA KLAYIFKDLY SAVISAKDEK 2250
GELLSAPFTN LPPKRKLPAY YQRVSDPIDL ITIEQNINTG NYKTIEAFDQ 2300
DMTKLFNNNV KFYGRTSELG IASTRLRRVY CLAKYDSASE LEKVLGDAIP 2350
SSFIPENANP GDEEEDVIRC ICGLYKDEGV MIQCERCLVW QHCDCVKADD 2400
SVEHYLCERC DPREVNLEIL IDPQPEYATE DTTHYISLLR GDLQLRIGDA 2450
VYVLRDMIEE NTPKTSPPTK VTYKTIQNVN YADLDIFRIE RLWIDKKGDK 2500
FAFGHHYLRP HETYHEPTRK FFHNEVMRVP LYEVVPLDLI MNHCWVLDLN 2550
TYCKGRPIGA PEEHIYICEY RVDKSAHLFA KIAKPYLICT KTYAFEKFDV 2600
RLKPTRTYTV HEAKSESLKQ SESDEELPLA KIKENVHAAK RDEQKKRLNS 2650
ILLKLLSRLP NKQPLDLSYL LEPVKRFRGK AQQQGKRT 2688
Length:2,688
Mass (Da):306,122
Last modified:November 2, 2010 - v1
Checksum:iB999A46F4626BEFE
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS235222 Genomic DNA. Translation: EEB13517.1.
RefSeqiXP_002426255.1. XM_002426210.1.

Genome annotation databases

GeneIDi8230790.
KEGGiphu:Phum_PHUM244720.
VectorBaseiPHUM244720. Pediculus humanus.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS235222 Genomic DNA. Translation: EEB13517.1 .
RefSeqi XP_002426255.1. XM_002426210.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 8230790.
KEGGi phu:Phum_PHUM244720.
VectorBasei PHUM244720. Pediculus humanus.

Organism-specific databases

CTDi 8230790.

Phylogenomic databases

KOi K06101.
OrthoDBi EOG7ZPNJ4.

Family and domain databases

Gene3Di 1.20.920.10. 1 hit.
3.30.40.10. 1 hit.
InterProi IPR017956. AT_hook_DNA-bd_motif.
IPR006560. AWS.
IPR001025. BAH_dom.
IPR001487. Bromodomain.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
IPR019786. Zinc_finger_PHD-type_CS.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view ]
Pfami PF01426. BAH. 1 hit.
PF00439. Bromodomain. 1 hit.
PF00856. SET. 1 hit.
[Graphical view ]
SMARTi SM00384. AT_hook. 4 hits.
SM00570. AWS. 1 hit.
SM00439. BAH. 1 hit.
SM00297. BROMO. 1 hit.
SM00249. PHD. 1 hit.
SM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view ]
SUPFAMi SSF47370. SSF47370. 1 hit.
SSF57903. SSF57903. 1 hit.
PROSITEi PS51215. AWS. 1 hit.
PS51038. BAH. 1 hit.
PS50014. BROMODOMAIN_2. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
PS01359. ZF_PHD_1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequences of the human body louse and its primary endosymbiont provide insights into the permanent parasitic lifestyle."
    Kirkness E.F., Haas B.J., Sun W., Braig H.R., Perotti M.A., Clark J.M., Lee S.H., Robertson H.M., Kennedy R.C., Elhaik E., Gerlach D., Kriventseva E.V., Elsik C.G., Graur D., Hill C.A., Veenstra J.A., Walenz B., Tubio J.M.
    , Ribeiro J.M., Rozas J., Johnston J.S., Reese J.T., Popadic A., Tojo M., Raoult D., Reed D.L., Tomoyasu Y., Krause E., Mittapalli O., Margam V.M., Li H.M., Meyer J.M., Johnson R.M., Romero-Severson J., Vanzee J.P., Alvarez-Ponce D., Vieira F.G., Aguade M., Guirao-Rico S., Anzola J.M., Yoon K.S., Strycharz J.P., Unger M.F., Christley S., Lobo N.F., Seufferheld M.J., Wang N., Dasch G.A., Struchiner C.J., Madey G., Hannick L.I., Bidwell S., Joardar V., Caler E., Shao R., Barker S.C., Cameron S., Bruggner R.V., Regier A., Johnson J., Viswanathan L., Utterback T.R., Sutton G.G., Lawson D., Waterhouse R.M., Venter J.C., Strausberg R.L., Berenbaum M.R., Collins F.H., Zdobnov E.M., Pittendrigh B.R.
    Proc. Natl. Acad. Sci. U.S.A. 107:12168-12173(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: USDA.

Entry informationi

Entry nameiE0VJG1_PEDHC
AccessioniPrimary (citable) accession number: E0VJG1
Entry historyi
Integrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 2, 2010
Last modified: July 9, 2014
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3