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E0VG84

- E0VG84_PEDHC

UniProt

E0VG84 - E0VG84_PEDHC

Protein

DNA ligase

Gene

Phum_PHUM175060

Organism
Pediculus humanus subsp. corporis (Body louse)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 21 (01 Oct 2014)
      Sequence version 1 (02 Nov 2010)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. DNA binding Source: InterPro
    3. DNA ligase (ATP) activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA ligation involved in DNA repair Source: InterPro
    2. DNA recombination Source: UniProtKB-KW
    3. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseUniRule annotationImported

    Keywords - Biological processi

    DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
    Gene namesi
    ORF Names:Phum_PHUM175060Imported
    OrganismiPediculus humanus subsp. corporis (Body louse)Imported
    Taxonomic identifieri121224 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraParaneopteraPhthirapteraAnopluraPediculidaePediculus
    ProteomesiUP000009046: Partially assembled WGS sequence

    Structurei

    3D structure databases

    ProteinModelPortaliE0VG84.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ATP-dependent DNA ligase family.UniRule annotation

    Phylogenomic databases

    KOiK10747.
    OMAiLDPSGYN.
    OrthoDBiEOG7RFTGN.
    PhylomeDBiE0VG84.

    Family and domain databases

    Gene3Di1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    InterProiIPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view]
    PfamiPF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsiTIGR00574. dnl1. 1 hit.
    PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E0VG84-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGETTITPNQ EYKIVSNTKS YDIISKFFLI SSADENSPIK ATGSKKRLRI    50
    SSSSSDKDSE TDDLETTEKK SVDSRIKKTS QKVAKLTTSS KVNPLQSSDN 100
    SITDKKDNLD KKNCTNIEKS NNITSESKTE KVEKTNKKDS SPVKEKVSKC 150
    NVLVEDYNPT LPKYHPIKNA CWEYGEKVPY YALTKTFEEI EKVSARLKMI 200
    EILSNFLRSV IVLTPDDLLP CIYLSLNKLG PAHEGLELGL AEQTLIRVIS 250
    QSTGRTEVGD LGLVAEKSRT SQKLMFKPSP LNVNGVFKKF TEIANLTGKD 300
    SVNKKISMVS NLFTACKGPE AKFLMRSLNG KLRIACATTP PGQKYPPKNL 350
    DVSSTMSPDT FKSHVDELAL ILKTTYCECP NYGMLVPVLL KEGISALPKH 400
    CKITPGLPMK PMLAQPTKGV QEVLTRFEDM EFTCEWKYDG ERAQIHYLEN 450
    GKVKIFSRNQ EDNTSKYPDI ISRIQQVKKD SVTSFILDCE AVAWDKENNA 500
    ILPFQVLIKR KRKDVAESDI KVPVCVYMFD LLYLNGKPLV KEKFIDRRRL 550
    LQENFNEVLG EWTFAKSIDT TKMEEVQEFL EESIKGNCEG LMVKTLREEA 600
    TYEIAKRSKN WLKLKKDYLE GVGDTLDLVV LGGYLGKGKR TGTYGGFLIG 650
    CYDNDNEEYQ SICKLGTGFS DESLAQHTEF FKPHVITQAP SYYQYDTSME 700
    PDHWFEPIQV WETKCADFSL SPIHRAAVGV VDPVKGISLR FPRFLRIRDD 750
    KKPEDATTAQ QIIDLYHNQE QVKCQNSVKF QEEDFY 786
    Length:786
    Mass (Da):89,086
    Last modified:November 2, 2010 - v1
    Checksum:i234F6D739D7B1CFD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS235132 Genomic DNA. Translation: EEB12390.1.
    RefSeqiXP_002425128.1. XM_002425083.1.

    Genome annotation databases

    GeneIDi8236783.
    KEGGiphu:Phum_PHUM175060.
    VectorBaseiPHUM175060. Pediculus humanus.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS235132 Genomic DNA. Translation: EEB12390.1 .
    RefSeqi XP_002425128.1. XM_002425083.1.

    3D structure databases

    ProteinModelPortali E0VG84.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 8236783.
    KEGGi phu:Phum_PHUM175060.
    VectorBasei PHUM175060. Pediculus humanus.

    Organism-specific databases

    CTDi 8236783.

    Phylogenomic databases

    KOi K10747.
    OMAi LDPSGYN.
    OrthoDBi EOG7RFTGN.
    PhylomeDBi E0VG84.

    Family and domain databases

    Gene3Di 1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    InterProi IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view ]
    Pfami PF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsi TIGR00574. dnl1. 1 hit.
    PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequences of the human body louse and its primary endosymbiont provide insights into the permanent parasitic lifestyle."
      Kirkness E.F., Haas B.J., Sun W., Braig H.R., Perotti M.A., Clark J.M., Lee S.H., Robertson H.M., Kennedy R.C., Elhaik E., Gerlach D., Kriventseva E.V., Elsik C.G., Graur D., Hill C.A., Veenstra J.A., Walenz B., Tubio J.M.
      , Ribeiro J.M., Rozas J., Johnston J.S., Reese J.T., Popadic A., Tojo M., Raoult D., Reed D.L., Tomoyasu Y., Krause E., Mittapalli O., Margam V.M., Li H.M., Meyer J.M., Johnson R.M., Romero-Severson J., Vanzee J.P., Alvarez-Ponce D., Vieira F.G., Aguade M., Guirao-Rico S., Anzola J.M., Yoon K.S., Strycharz J.P., Unger M.F., Christley S., Lobo N.F., Seufferheld M.J., Wang N., Dasch G.A., Struchiner C.J., Madey G., Hannick L.I., Bidwell S., Joardar V., Caler E., Shao R., Barker S.C., Cameron S., Bruggner R.V., Regier A., Johnson J., Viswanathan L., Utterback T.R., Sutton G.G., Lawson D., Waterhouse R.M., Venter J.C., Strausberg R.L., Berenbaum M.R., Collins F.H., Zdobnov E.M., Pittendrigh B.R.
      Proc. Natl. Acad. Sci. U.S.A. 107:12168-12173(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: USDAImported.

    Entry informationi

    Entry nameiE0VG84_PEDHC
    AccessioniPrimary (citable) accession number: E0VG84
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 2, 2010
    Last sequence update: November 2, 2010
    Last modified: October 1, 2014
    This is version 21 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3