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Protein

DNA ligase

Gene

8236783

Organism
Pediculus humanus subsp. corporis (Body louse)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n)-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)(m) = (deoxyribonucleotide)(n+m) + AMP + diphosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigaseUniRule annotationImported
Biological processDNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
Name:8236783Imported
ORF Names:Phum_PHUM175060Imported
OrganismiPediculus humanus subsp. corporis (Body louse)Imported
Taxonomic identifieri121224 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraParaneopteraPsocodeaPhthirapteraAnopluraPediculidaePediculus
Proteomesi
  • UP000009046 Componenti: Partially assembled WGS sequence

Interactioni

Protein-protein interaction databases

STRINGi121225.PHUM175060-PA

Structurei

3D structure databases

ProteinModelPortaliE0VG84
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini517 – 653DNA_LIGASE_A3InterPro annotationAdd BLAST137

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

InParanoidiE0VG84
KOiK10747
OMAiWIKYKRD
PhylomeDBiE0VG84

Family and domain databases

Gene3Di1.10.3260.10, 1 hit
InterProiView protein in InterPro
IPR000977 DNA_ligase_ATP-dep
IPR012309 DNA_ligase_ATP-dep_C
IPR012310 DNA_ligase_ATP-dep_cent
IPR016059 DNA_ligase_ATP-dep_CS
IPR012308 DNA_ligase_ATP-dep_N
IPR036599 DNA_ligase_N_sf
IPR012340 NA-bd_OB-fold
PfamiView protein in Pfam
PF04679 DNA_ligase_A_C, 1 hit
PF01068 DNA_ligase_A_M, 1 hit
PF04675 DNA_ligase_A_N, 1 hit
SUPFAMiSSF117018 SSF117018, 1 hit
SSF50249 SSF50249, 1 hit
TIGRFAMsiTIGR00574 dnl1, 1 hit
PROSITEiView protein in PROSITE
PS00697 DNA_LIGASE_A1, 1 hit
PS00333 DNA_LIGASE_A2, 1 hit
PS50160 DNA_LIGASE_A3, 1 hit

Sequencei

Sequence statusi: Complete.

E0VG84-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGETTITPNQ EYKIVSNTKS YDIISKFFLI SSADENSPIK ATGSKKRLRI
60 70 80 90 100
SSSSSDKDSE TDDLETTEKK SVDSRIKKTS QKVAKLTTSS KVNPLQSSDN
110 120 130 140 150
SITDKKDNLD KKNCTNIEKS NNITSESKTE KVEKTNKKDS SPVKEKVSKC
160 170 180 190 200
NVLVEDYNPT LPKYHPIKNA CWEYGEKVPY YALTKTFEEI EKVSARLKMI
210 220 230 240 250
EILSNFLRSV IVLTPDDLLP CIYLSLNKLG PAHEGLELGL AEQTLIRVIS
260 270 280 290 300
QSTGRTEVGD LGLVAEKSRT SQKLMFKPSP LNVNGVFKKF TEIANLTGKD
310 320 330 340 350
SVNKKISMVS NLFTACKGPE AKFLMRSLNG KLRIACATTP PGQKYPPKNL
360 370 380 390 400
DVSSTMSPDT FKSHVDELAL ILKTTYCECP NYGMLVPVLL KEGISALPKH
410 420 430 440 450
CKITPGLPMK PMLAQPTKGV QEVLTRFEDM EFTCEWKYDG ERAQIHYLEN
460 470 480 490 500
GKVKIFSRNQ EDNTSKYPDI ISRIQQVKKD SVTSFILDCE AVAWDKENNA
510 520 530 540 550
ILPFQVLIKR KRKDVAESDI KVPVCVYMFD LLYLNGKPLV KEKFIDRRRL
560 570 580 590 600
LQENFNEVLG EWTFAKSIDT TKMEEVQEFL EESIKGNCEG LMVKTLREEA
610 620 630 640 650
TYEIAKRSKN WLKLKKDYLE GVGDTLDLVV LGGYLGKGKR TGTYGGFLIG
660 670 680 690 700
CYDNDNEEYQ SICKLGTGFS DESLAQHTEF FKPHVITQAP SYYQYDTSME
710 720 730 740 750
PDHWFEPIQV WETKCADFSL SPIHRAAVGV VDPVKGISLR FPRFLRIRDD
760 770 780
KKPEDATTAQ QIIDLYHNQE QVKCQNSVKF QEEDFY
Length:786
Mass (Da):89,086
Last modified:November 2, 2010 - v1
Checksum:i234F6D739D7B1CFD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS235132 Genomic DNA Translation: EEB12390.1
RefSeqiXP_002425128.1, XM_002425083.1

Genome annotation databases

EnsemblMetazoaiPHUM175060-RA; PHUM175060-PA; PHUM175060
GeneIDi8236783
KEGGiphu:Phum_PHUM175060
VectorBaseiPHUM175060-RA; PHUM175060-PA; PHUM175060

Similar proteinsi

Entry informationi

Entry nameiE0VG84_PEDHC
AccessioniPrimary (citable) accession number: E0VG84
Entry historyiIntegrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 2, 2010
Last modified: March 28, 2018
This is version 39 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health