Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

E0VC46

- E0VC46_PEDHC

UniProt

E0VC46 - E0VC46_PEDHC

Protein
Submitted name:

Mixed-lineage leukemia protein, mll, putative

Gene

Phum_PHUM079870

Organism
Pediculus humanus subsp. corporis (Body louse)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 30 (01 Oct 2014)
      Sequence version 1 (02 Nov 2010)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].SAAS annotation

    GO - Molecular functioni

    1. DNA-directed RNA polymerase activity Source: InterPro
    2. histone-lysine N-methyltransferase activity Source: UniProtKB-EC
    3. RNA binding Source: InterPro
    4. sequence-specific DNA binding Source: InterPro
    5. sequence-specific DNA binding transcription factor activity Source: InterPro
    6. zinc ion binding Source: InterPro

    GO - Biological processi

    1. transcription, DNA-templated Source: InterPro

    Keywords - Molecular functioni

    MethyltransferaseUniRule annotationSAAS annotationImported, Transferase

    Keywords - Ligandi

    Metal-binding, S-adenosyl-L-methionineSAAS annotation, Zinc

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Mixed-lineage leukemia protein, mll, putativeImported (EC:2.1.1.43Imported)
    Gene namesi
    ORF Names:Phum_PHUM079870Imported
    OrganismiPediculus humanus subsp. corporis (Body louse)Imported
    Taxonomic identifieri121224 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraParaneopteraPhthirapteraAnopluraPediculidaePediculus
    ProteomesiUP000009046: Partially assembled WGS sequence

    Subcellular locationi

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-KW

    Keywords - Cellular componenti

    NucleusSAAS annotation

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 post-SET domain.UniRule annotation
    Contains SET domain.SAAS annotation
    Contains post-SET domain.SAAS annotation

    Keywords - Domaini

    Zinc-fingerSAAS annotation

    Phylogenomic databases

    KOiK09186.
    OMAiARCEPYS.
    OrthoDBiEOG75XGJZ.
    PhylomeDBiE0VC46.

    Family and domain databases

    Gene3Di2.40.50.140. 1 hit.
    3.30.1490.120. 1 hit.
    3.30.40.10. 2 hits.
    InterProiIPR003889. FYrich_C.
    IPR003888. FYrich_N.
    IPR012340. NA-bd_OB-fold.
    IPR003616. Post-SET_dom.
    IPR003029. Rbsml_prot_S1_RNA-bd_dom.
    IPR022967. RNA-binding_domain_S1.
    IPR005576. RNA_pol_Rpb7_N.
    IPR001214. SET_dom.
    IPR011011. Znf_FYVE_PHD.
    IPR001628. Znf_hrmn_rcpt.
    IPR001965. Znf_PHD.
    IPR019787. Znf_PHD-finger.
    IPR001841. Znf_RING.
    IPR013083. Znf_RING/FYVE/PHD.
    [Graphical view]
    PfamiPF05965. FYRC. 1 hit.
    PF05964. FYRN. 1 hit.
    PF00575. S1. 1 hit.
    PF00856. SET. 1 hit.
    PF03876. SHS2_Rpb7-N. 1 hit.
    [Graphical view]
    SMARTiSM00249. PHD. 4 hits.
    SM00508. PostSET. 1 hit.
    SM00184. RING. 4 hits.
    SM00316. S1. 1 hit.
    SM00317. SET. 1 hit.
    [Graphical view]
    SUPFAMiSSF50249. SSF50249. 1 hit.
    SSF57903. SSF57903. 3 hits.
    SSF88798. SSF88798. 1 hit.
    PROSITEiPS51543. FYRC. 1 hit.
    PS51542. FYRN. 1 hit.
    PS51030. NUCLEAR_REC_DBD_2. 1 hit.
    PS50868. POST_SET. 1 hit.
    PS50280. SET. 1 hit.
    PS50016. ZF_PHD_2. 3 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E0VC46-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKISLEHEIL LHPRYFGPQL LETVKQKLYA EVEGTCTGKY GFVIAVTLID     50
    NIGAGLILPG QGFVVYPVKY RAIVFRPFKG EVLDAVVTQV NKVGMFAEIG 100
    PLSCFISHHS IPADMQFCPN FNPPCYKSKD EDVVIQADDE IRLKIVGTRV 150
    DASGIFAIGT LMDDYLGLVG LTSVVAKMAT DRSLADRGIV EIKMGRSKFP 200
    GKPTKIGNRK RVNLSSCSLP EDNDSSTAAK NIYLGLSMFN ETFGDNETIT 250
    PGPFYGFSSN EIDEAMAEAR LQQKEAEVAH KKQGIDINFW DSFQSELFSV 300
    SSFTKHKLLP DNNCEKESKT IVSFDGGGLP FDFPFSHDNS DNEPSRTLNV 350
    NVVENNKVHK INKKVRISSK LEKTSSKIKK LRAPRFKFNK NKLQCSPIAN 400
    RSLQSQAAKK LLNKAKMTNL LEINKNLPAD KKFILPSRST HSSRVIKPNK 450
    RFFEDNIIKK KYLNSQSCLN ATVNNKQNLL EESRKKFETR KLHWENKSSE 500
    NLNLSESSNS SSSKFILREA RLQLDKDKTQ TSVLEGPFSS PNLSSLCSNT 550
    QLKINLMQST PGNKECAVCG IVIFCKFVEK PKEFGIFCCE NCQKFIWKII 600
    KSLESKKDFK LQCLKGNGLC EIVNIMKAQH FNVIESSYST KCQACWLKLC 650
    LKNFKMPNKL KQNLLKVLPV NMQINLSLDY GPTSSDTSSS KFRFSAKNMK 700
    HFKWFNENNS QEIRAVNKNN IIDLPWSNIS ESNILNKKVL RKRTKNGENT 750
    VQSNIFLGQN EKIKSVNDKN RQSIVLKGPR VKHVCRSASV ALGQPLATFP 800
    TDLGSKKKKT NESSEDCNKC TTSPSPESNG VECQEVEFFS ENVVDSKEEG 850
    KEKKLNTFKE TTCNLKEVQV SRLNNGVKSK KKTNIKIENP VSMDFWESYD 900
    PDEICETGFC LIGSEDFSVR ALCFLCGSSG QEKLIHCASC CEPYHEFCID 950
    EAQLKLQNNT WKFDWVCPRC TVCFTCGKTS GQQLKCVKCD NSYHIECVDR 1000
    VGGRLLHSPD RPWVCSICLR CKSCNGVDVS VFVGNLPLCR ACFVLRQKGN 1050
    FCPLCQRCYN DDDYDSKMME CGQCKCWVHA KCEGLSDEKY QVLSFLPESV 1100
    EYVCRMCCVM PPAPWWIAVE AELKSGYLGV LKALSKNRKA CTMLKWSPRK 1150
    QCTCRPVEYT SRAFDLDVLN RTSKMLDVEL EEISNSEKEI NEKKKIHEEK 1200
    EMIEKYQPAI LSERKTSIEV INHPTESLKL TLKIMKNCDT ETENITESTT 1250
    KDKSVKDIFD DEKLQENSER VKNLIANQKF SDNSQSVNRK ISPFEYNKVN 1300
    SSNSGNTLDS DAGNSAKDRS SIYDQNCFQL SSLETNKANG DISVNLLEGT 1350
    RECVCFLDVE SYNSRSKPFS PNLMSIKKKV TTSEYSSLHQ FHQDMERMIA 1400
    TSHSTELMDL YHQTIREIFP WFDPKFSKVQ NSSQKVSSIK SAESTPVKST 1450
    PKKIIPEEEC KIPKYKLYDQ PLDYFYSDYT VQDTRICVMC KVVGDGLPGH 1500
    TGRLLYCGQN EWVHCNCALW SGEVFEEIDG SLQNVHSAIS RSRSIKCPEC 1550
    NLKGASIGCC ARSCQETYHF SCAKKLGCAF MDDKTMYCLA HLKDVNNKLV 1600
    QNEKEFEIRR PVYVELDKRK MKTADSCQIR FVVGSLHVNN LGKFAGKLSD 1650
    ETKSIIPDQF SCTRLFWSCF EPWRIVRYHF SVRLVEAENT QGVDTGINLT 1700
    VDHSKDPELV ELKLKQLKYF QENNSFLEIN EKLVENQLGE KRKLVELKAK 1750
    CDKIKISDSN SPKKDKKNQK VVRKILDQYD FKDDENCLSD NQNTADLLPP 1800
    DVEEAIFKDL PHDILDGISM QDIFMDIKNY EYNSKENSEE LYEGDDNLFN 1850
    SLNKIHKKNE NIQNESIWTE SIDCKLEVIG ETSLVSKSRN VKRNRTDDSL 1900
    LLPSKKSTTL KTYQKSTNLN RNYKCENFNN KWKKHSKCHV TVNLLEPQER 1950
    GNMLQELKFT DGLVSITTGA IGSMKDLKSR LEDNKRSIQE EGKENKFLAW 2000
    QTRLQPRLLQ VDGGVDSSSS GSEAGESPQR MTEESVTSKL VDSSSQILDP 2050
    LYSIKSSNVP EFQNFSTSEN SHHSNKSSVS FSKGNTDSNS FILPQVDGVE 2100
    DCNSDVSDSE IQNCKKYSLK EIQNFNKVMV RKRDLINVFD LNYKIVQCDG 2150
    GVDSECEEET FKNCNLSDGS VYPLVAKVEE EPVKCGKCRC TYRTKISYQR 2200
    HLESCTSDFI LSSSEAEMSD EESPKRHFNN ISLKQKSDNI NALAIPAKTT 2250
    NKEHSKKNIS YNSHLANDSL QISSHLNPIN FEKPEVKKEK VKKTYTRRKV 2300
    PTATKKNSPV NNKQQVQQIL LQQQSAAAAP ALIVQDVTGS NLMSTAYIDS 2350
    TPTLGYLAGI ESQHFLNKTQ LISTPGGVIS GNFHVPSPSE SQVLGGLCLN 2400
    TQNVQNNFPG FIIQQQPNIQ GPVLSSQNSP VILSNEQLMV GSTDSYNVFQ 2450
    DPRTGGMFLT SRNAPVFYNM ETIVSNTVMQ TNQFVSNVLG TTFSQTSTQI 2500
    FQASEMEQIV NVPSNYILVN SNHAGANRLF PSNDLLCVQT QPTFIQNQTP 2550
    IQLGSSNQTV QPSQIFNPSI PTAQILNFDP KTLPIQNNSF RCLQPVCPPI 2600
    ILGKVSNGLN NNVVNSTVPQ VLQKTPASTP TIVNPVVTSK SVPTIKPQQL 2650
    NGFSSSQMTK LPVKIPEKPA IPLKSNPQSQ IQSRSRALVD YINNFRSEAN 2700
    ETLLKSAQVQ NKTKNNICDK SSSQSYNLNS SNKSINLNTC ISTQQKVMQN 2750
    QNNFHKSSSL STELVNPSCK TEVKSTNNLK IPKSASSELL VTKAEIQSPA 2800
    SLKSEKIILP AKPLAANEPI PSVKNFKIKN EKITSCTKTE ESCPRRESSL 2850
    ISTSEETEKS PCAGVKIFQN LPPSNFEMQE KEDGSTVPDS KNIEISMHED 2900
    SRPVKDEYPK QDNNTNHVLP LQENCQKINI SPKNNNVKSS PKGHSKDGEN 2950
    LFLKQEENYK IKRKINFLDQ NSFDSKSLGI NDKFESPPDK DASEVVADEN 3000
    ISFSKKSIEE KGPKLIFDVI SDDGFKKSSS SMAELWANIC DSVQEMRAML 3050
    KIPSLPLTKK DYEILGMQNH GLQHCLEQLK GVENCVNYKF KYFTRDDSRR 3100
    DSEDEVKENP SGCARTEKFT NRKEYDMFAW LASKHRKLPK LTESAEETLC 3150
    SIRRANNLPM AMKYRNLKET SKLYVGVYRS QIHGRGLFCL REIEAGEMVI 3200
    EYAGEVIRAN LSDKREKYYT EKGIGCYMFR IDDHFVVDAT MKGNAARFIN 3250
    HSCEPNCYSR VVDILGKKHI VIFALRKINI MEELTYDYKF PFEDEKISCH 3300
    CLSKKCKKYL N 3311
    Length:3,311
    Mass (Da):374,070
    Last modified:November 2, 2010 - v1
    Checksum:i4FAE8C5D6519026D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS235047 Genomic DNA. Translation: EEB10952.1.
    RefSeqiXP_002423690.1. XM_002423645.1.

    Genome annotation databases

    GeneIDi8231358.
    KEGGiphu:Phum_PHUM079870.
    VectorBaseiPHUM079870. Pediculus humanus.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS235047 Genomic DNA. Translation: EEB10952.1 .
    RefSeqi XP_002423690.1. XM_002423645.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 8231358.
    KEGGi phu:Phum_PHUM079870.
    VectorBasei PHUM079870. Pediculus humanus.

    Organism-specific databases

    CTDi 8231358.

    Phylogenomic databases

    KOi K09186.
    OMAi ARCEPYS.
    OrthoDBi EOG75XGJZ.
    PhylomeDBi E0VC46.

    Family and domain databases

    Gene3Di 2.40.50.140. 1 hit.
    3.30.1490.120. 1 hit.
    3.30.40.10. 2 hits.
    InterProi IPR003889. FYrich_C.
    IPR003888. FYrich_N.
    IPR012340. NA-bd_OB-fold.
    IPR003616. Post-SET_dom.
    IPR003029. Rbsml_prot_S1_RNA-bd_dom.
    IPR022967. RNA-binding_domain_S1.
    IPR005576. RNA_pol_Rpb7_N.
    IPR001214. SET_dom.
    IPR011011. Znf_FYVE_PHD.
    IPR001628. Znf_hrmn_rcpt.
    IPR001965. Znf_PHD.
    IPR019787. Znf_PHD-finger.
    IPR001841. Znf_RING.
    IPR013083. Znf_RING/FYVE/PHD.
    [Graphical view ]
    Pfami PF05965. FYRC. 1 hit.
    PF05964. FYRN. 1 hit.
    PF00575. S1. 1 hit.
    PF00856. SET. 1 hit.
    PF03876. SHS2_Rpb7-N. 1 hit.
    [Graphical view ]
    SMARTi SM00249. PHD. 4 hits.
    SM00508. PostSET. 1 hit.
    SM00184. RING. 4 hits.
    SM00316. S1. 1 hit.
    SM00317. SET. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50249. SSF50249. 1 hit.
    SSF57903. SSF57903. 3 hits.
    SSF88798. SSF88798. 1 hit.
    PROSITEi PS51543. FYRC. 1 hit.
    PS51542. FYRN. 1 hit.
    PS51030. NUCLEAR_REC_DBD_2. 1 hit.
    PS50868. POST_SET. 1 hit.
    PS50280. SET. 1 hit.
    PS50016. ZF_PHD_2. 3 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequences of the human body louse and its primary endosymbiont provide insights into the permanent parasitic lifestyle."
      Kirkness E.F., Haas B.J., Sun W., Braig H.R., Perotti M.A., Clark J.M., Lee S.H., Robertson H.M., Kennedy R.C., Elhaik E., Gerlach D., Kriventseva E.V., Elsik C.G., Graur D., Hill C.A., Veenstra J.A., Walenz B., Tubio J.M.
      , Ribeiro J.M., Rozas J., Johnston J.S., Reese J.T., Popadic A., Tojo M., Raoult D., Reed D.L., Tomoyasu Y., Krause E., Mittapalli O., Margam V.M., Li H.M., Meyer J.M., Johnson R.M., Romero-Severson J., Vanzee J.P., Alvarez-Ponce D., Vieira F.G., Aguade M., Guirao-Rico S., Anzola J.M., Yoon K.S., Strycharz J.P., Unger M.F., Christley S., Lobo N.F., Seufferheld M.J., Wang N., Dasch G.A., Struchiner C.J., Madey G., Hannick L.I., Bidwell S., Joardar V., Caler E., Shao R., Barker S.C., Cameron S., Bruggner R.V., Regier A., Johnson J., Viswanathan L., Utterback T.R., Sutton G.G., Lawson D., Waterhouse R.M., Venter J.C., Strausberg R.L., Berenbaum M.R., Collins F.H., Zdobnov E.M., Pittendrigh B.R.
      Proc. Natl. Acad. Sci. U.S.A. 107:12168-12173(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: USDAImported.

    Entry informationi

    Entry nameiE0VC46_PEDHC
    AccessioniPrimary (citable) accession number: E0VC46
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 2, 2010
    Last sequence update: November 2, 2010
    Last modified: October 1, 2014
    This is version 30 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3