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E0VAB8

- E0VAB8_PEDHC

UniProt

E0VAB8 - E0VAB8_PEDHC

Protein
Submitted name:

Angiotensin-converting enzyme, putative

Gene

Phum_PHUM034490

Organism
Pediculus humanus subsp. corporis (Body louse)
Status
Unreviewed - Annotation score: 1 out of 5- Protein inferred from homologyi
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    • History
      Entry version 24 (01 Oct 2014)
      Sequence version 1 (02 Nov 2010)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 zinc ion per subunit.UniRule annotation
    Binds 2 zinc ions per subunit.UniRule annotation

    GO - Molecular functioni

    1. carboxypeptidase activity Source: UniProtKB-KW
    2. metallopeptidase activity Source: InterPro
    3. peptidyl-dipeptidase activity Source: InterPro

    Keywords - Molecular functioni

    CarboxypeptidaseUniRule annotationImported, Hydrolase, MetalloproteaseUniRule annotation, Protease

    Keywords - Ligandi

    Metal-bindingUniRule annotation, ZincUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Angiotensin-converting enzyme, putativeImported (EC:3.4.15.1Imported)
    Gene namesi
    ORF Names:Phum_PHUM034490Imported
    OrganismiPediculus humanus subsp. corporis (Body louse)Imported
    Taxonomic identifieri121224 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraParaneopteraPhthirapteraAnopluraPediculidaePediculus
    ProteomesiUP000009046: Partially assembled WGS sequence

    Subcellular locationi

    GO - Cellular componenti

    1. membrane Source: InterPro

    PTM / Processingi

    Keywords - PTMi

    GlycoproteinUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliE0VAB8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the peptidase M2 family.UniRule annotation

    Phylogenomic databases

    KOiK01283.
    OMAiWWELRLR.
    OrthoDBiEOG7N37C7.
    PhylomeDBiE0VAB8.

    Family and domain databases

    InterProiIPR001548. Peptidase_M2.
    [Graphical view]
    PANTHERiPTHR10514. PTHR10514. 1 hit.
    PfamiPF01401. Peptidase_M2. 1 hit.
    [Graphical view]
    PRINTSiPR00791. PEPDIPTASEA.

    Sequencei

    Sequence statusi: Complete.

    E0VAB8-1 [UniParc]FASTAAdd to Basket

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    MFLLFLFLFA KFAFSQDTTN IEGNNESLEE ALQFLREYDV EGSAICTRVT    50
    LAQWNFSTNV STINRKKMVC YNKCGNDYGR TVMEQTLYDK FQKLSRRKAT 100
    EFAWTKLPDP DVRRQMKKLI TQGRFSLHDD QFNELKDVIS QMKEIYTKGT 150
    ICPYNKNPVY CDQKLEPTLT KIMAKSRDYH ELLHVWKSWR DAVGPPIRQK 200
    YIRYVELANQ AARLDGFNDA GDQMKSVYEI PNFEDHLSEL WNMIEPFYKQ 250
    LHAYVRRKLI KFYGSKYIRH DGPIPAHLLG NMWAQSWKNI EELIIPYPGK 300
    TIGDITPELI RQVAEEFFIS LGLKPMPPEF WRHSLLEKPI GREVVCRASA 350
    WDFCNKMDYR IKQCTEVTME DFLTIHHEMA HIEYYLQYAD QPYLYREGAN 400
    PAFHEAVGDV IVLSVQTPRH LQRIGLLNNI TDDYETNINY LLSMALEKVV 450
    YLPFAYIVDK WRWNVFAEGI NNMNSKWWEL KLNYQGLIPP VPRSESDFDA 500
    AAKYHVASDT PYIRYFLSVI IQFQLYESLC EASGHYGPLH TCDIYRSREA 550
    GRLLREILQS GSSRSWSDVI NVMTKGKIKK ISASSLLNYF KPLLTWLEVQ 600
    NKEELYVGWT TGPHDTGKIM DDVITRR 627
    Length:627
    Mass (Da):73,489
    Last modified:November 2, 2010 - v1
    Checksum:i830344A1E3864A2B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS235005 Genomic DNA. Translation: EEB10324.1.
    RefSeqiXP_002423062.1. XM_002423017.1.

    Genome annotation databases

    GeneIDi8232297.
    KEGGiphu:Phum_PHUM034490.
    VectorBaseiPHUM034490. Pediculus humanus.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS235005 Genomic DNA. Translation: EEB10324.1 .
    RefSeqi XP_002423062.1. XM_002423017.1.

    3D structure databases

    ProteinModelPortali E0VAB8.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 8232297.
    KEGGi phu:Phum_PHUM034490.
    VectorBasei PHUM034490. Pediculus humanus.

    Organism-specific databases

    CTDi 8232297.

    Phylogenomic databases

    KOi K01283.
    OMAi WWELRLR.
    OrthoDBi EOG7N37C7.
    PhylomeDBi E0VAB8.

    Family and domain databases

    InterProi IPR001548. Peptidase_M2.
    [Graphical view ]
    PANTHERi PTHR10514. PTHR10514. 1 hit.
    Pfami PF01401. Peptidase_M2. 1 hit.
    [Graphical view ]
    PRINTSi PR00791. PEPDIPTASEA.
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequences of the human body louse and its primary endosymbiont provide insights into the permanent parasitic lifestyle."
      Kirkness E.F., Haas B.J., Sun W., Braig H.R., Perotti M.A., Clark J.M., Lee S.H., Robertson H.M., Kennedy R.C., Elhaik E., Gerlach D., Kriventseva E.V., Elsik C.G., Graur D., Hill C.A., Veenstra J.A., Walenz B., Tubio J.M.
      , Ribeiro J.M., Rozas J., Johnston J.S., Reese J.T., Popadic A., Tojo M., Raoult D., Reed D.L., Tomoyasu Y., Krause E., Mittapalli O., Margam V.M., Li H.M., Meyer J.M., Johnson R.M., Romero-Severson J., Vanzee J.P., Alvarez-Ponce D., Vieira F.G., Aguade M., Guirao-Rico S., Anzola J.M., Yoon K.S., Strycharz J.P., Unger M.F., Christley S., Lobo N.F., Seufferheld M.J., Wang N., Dasch G.A., Struchiner C.J., Madey G., Hannick L.I., Bidwell S., Joardar V., Caler E., Shao R., Barker S.C., Cameron S., Bruggner R.V., Regier A., Johnson J., Viswanathan L., Utterback T.R., Sutton G.G., Lawson D., Waterhouse R.M., Venter J.C., Strausberg R.L., Berenbaum M.R., Collins F.H., Zdobnov E.M., Pittendrigh B.R.
      Proc. Natl. Acad. Sci. U.S.A. 107:12168-12173(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: USDAImported.

    Entry informationi

    Entry nameiE0VAB8_PEDHC
    AccessioniPrimary (citable) accession number: E0VAB8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 2, 2010
    Last sequence update: November 2, 2010
    Last modified: October 1, 2014
    This is version 24 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3