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E0VAB8

- E0VAB8_PEDHC

UniProt

E0VAB8 - E0VAB8_PEDHC

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Protein
Submitted name:

Angiotensin-converting enzyme, putative

Gene

Phum_PHUM034490

Organism
Pediculus humanus subsp. corporis (Body louse)
Status
Unreviewed - Annotation score: 1 out of 5- Protein inferred from homologyi

Functioni

Cofactori

Binds 1 zinc ion per subunit.UniRule annotation
Binds 2 zinc ions per subunit.UniRule annotation

GO - Molecular functioni

  1. carboxypeptidase activity Source: UniProtKB-KW
  2. metal ion binding Source: UniProtKB-KW
  3. metallopeptidase activity Source: UniProtKB-KW
  4. peptidyl-dipeptidase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

CarboxypeptidaseUniRule annotationImported, Hydrolase, MetalloproteaseUniRule annotation, Protease

Keywords - Ligandi

Metal-bindingUniRule annotation, ZincUniRule annotation

Protein family/group databases

MEROPSiM02.005.

Names & Taxonomyi

Protein namesi
Submitted name:
Angiotensin-converting enzyme, putativeImported (EC:3.4.15.1Imported)
Gene namesi
ORF Names:Phum_PHUM034490Imported
OrganismiPediculus humanus subsp. corporis (Body louse)Imported
Taxonomic identifieri121224 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraParaneopteraPhthirapteraAnopluraPediculidaePediculus
ProteomesiUP000009046: Partially assembled WGS sequence

Subcellular locationi

GO - Cellular componenti

  1. membrane Source: InterPro
Complete GO annotation...

PTM / Processingi

Keywords - PTMi

GlycoproteinUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliE0VAB8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase M2 family.UniRule annotation

Phylogenomic databases

InParanoidiE0VAB8.
KOiK01283.
OMAiWWELRLR.
OrthoDBiEOG7N37C7.
PhylomeDBiE0VAB8.

Family and domain databases

InterProiIPR001548. Peptidase_M2.
[Graphical view]
PANTHERiPTHR10514. PTHR10514. 1 hit.
PfamiPF01401. Peptidase_M2. 1 hit.
[Graphical view]
PRINTSiPR00791. PEPDIPTASEA.

Sequencei

Sequence statusi: Complete.

E0VAB8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MFLLFLFLFA KFAFSQDTTN IEGNNESLEE ALQFLREYDV EGSAICTRVT
60 70 80 90 100
LAQWNFSTNV STINRKKMVC YNKCGNDYGR TVMEQTLYDK FQKLSRRKAT
110 120 130 140 150
EFAWTKLPDP DVRRQMKKLI TQGRFSLHDD QFNELKDVIS QMKEIYTKGT
160 170 180 190 200
ICPYNKNPVY CDQKLEPTLT KIMAKSRDYH ELLHVWKSWR DAVGPPIRQK
210 220 230 240 250
YIRYVELANQ AARLDGFNDA GDQMKSVYEI PNFEDHLSEL WNMIEPFYKQ
260 270 280 290 300
LHAYVRRKLI KFYGSKYIRH DGPIPAHLLG NMWAQSWKNI EELIIPYPGK
310 320 330 340 350
TIGDITPELI RQVAEEFFIS LGLKPMPPEF WRHSLLEKPI GREVVCRASA
360 370 380 390 400
WDFCNKMDYR IKQCTEVTME DFLTIHHEMA HIEYYLQYAD QPYLYREGAN
410 420 430 440 450
PAFHEAVGDV IVLSVQTPRH LQRIGLLNNI TDDYETNINY LLSMALEKVV
460 470 480 490 500
YLPFAYIVDK WRWNVFAEGI NNMNSKWWEL KLNYQGLIPP VPRSESDFDA
510 520 530 540 550
AAKYHVASDT PYIRYFLSVI IQFQLYESLC EASGHYGPLH TCDIYRSREA
560 570 580 590 600
GRLLREILQS GSSRSWSDVI NVMTKGKIKK ISASSLLNYF KPLLTWLEVQ
610 620
NKEELYVGWT TGPHDTGKIM DDVITRR
Length:627
Mass (Da):73,489
Last modified:November 2, 2010 - v1
Checksum:i830344A1E3864A2B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS235005 Genomic DNA. Translation: EEB10324.1.
RefSeqiXP_002423062.1. XM_002423017.1.

Genome annotation databases

EnsemblMetazoaiPHUM034490-RA; PHUM034490-PA; PHUM034490.
GeneIDi8232297.
KEGGiphu:Phum_PHUM034490.
VectorBaseiPHUM034490. Pediculus humanus.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS235005 Genomic DNA. Translation: EEB10324.1 .
RefSeqi XP_002423062.1. XM_002423017.1.

3D structure databases

ProteinModelPortali E0VAB8.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

MEROPSi M02.005.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai PHUM034490-RA ; PHUM034490-PA ; PHUM034490 .
GeneIDi 8232297.
KEGGi phu:Phum_PHUM034490.
VectorBasei PHUM034490. Pediculus humanus.

Organism-specific databases

CTDi 8232297.

Phylogenomic databases

InParanoidi E0VAB8.
KOi K01283.
OMAi WWELRLR.
OrthoDBi EOG7N37C7.
PhylomeDBi E0VAB8.

Family and domain databases

InterProi IPR001548. Peptidase_M2.
[Graphical view ]
PANTHERi PTHR10514. PTHR10514. 1 hit.
Pfami PF01401. Peptidase_M2. 1 hit.
[Graphical view ]
PRINTSi PR00791. PEPDIPTASEA.
ProtoNeti Search...

Publicationsi

  1. "Genome sequences of the human body louse and its primary endosymbiont provide insights into the permanent parasitic lifestyle."
    Kirkness E.F., Haas B.J., Sun W., Braig H.R., Perotti M.A., Clark J.M., Lee S.H., Robertson H.M., Kennedy R.C., Elhaik E., Gerlach D., Kriventseva E.V., Elsik C.G., Graur D., Hill C.A., Veenstra J.A., Walenz B., Tubio J.M.
    , Ribeiro J.M., Rozas J., Johnston J.S., Reese J.T., Popadic A., Tojo M., Raoult D., Reed D.L., Tomoyasu Y., Krause E., Mittapalli O., Margam V.M., Li H.M., Meyer J.M., Johnson R.M., Romero-Severson J., Vanzee J.P., Alvarez-Ponce D., Vieira F.G., Aguade M., Guirao-Rico S., Anzola J.M., Yoon K.S., Strycharz J.P., Unger M.F., Christley S., Lobo N.F., Seufferheld M.J., Wang N., Dasch G.A., Struchiner C.J., Madey G., Hannick L.I., Bidwell S., Joardar V., Caler E., Shao R., Barker S.C., Cameron S., Bruggner R.V., Regier A., Johnson J., Viswanathan L., Utterback T.R., Sutton G.G., Lawson D., Waterhouse R.M., Venter J.C., Strausberg R.L., Berenbaum M.R., Collins F.H., Zdobnov E.M., Pittendrigh B.R.
    Proc. Natl. Acad. Sci. U.S.A. 107:12168-12173(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: USDAImported.

Entry informationi

Entry nameiE0VAB8_PEDHC
AccessioniPrimary (citable) accession number: E0VAB8
Entry historyi
Integrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 2, 2010
Last modified: October 29, 2014
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3