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Protein

Transporter

Gene

SLC6A18

Organism
Microtus ochrogaster (Prairie vole)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Biological processSymportUniRule annotationSAAS annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
TransporterUniRule annotation
Gene namesi
Name:SLC6A18Imported
OrganismiMicrotus ochrogaster (Prairie vole)Imported
Taxonomic identifieri79684 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaCricetidaeArvicolinaeMicrotus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei26 – 44HelicalSequence analysisAdd BLAST19
Transmembranei56 – 77HelicalSequence analysisAdd BLAST22
Transmembranei98 – 126HelicalSequence analysisAdd BLAST29
Transmembranei178 – 197HelicalSequence analysisAdd BLAST20
Transmembranei209 – 232HelicalSequence analysisAdd BLAST24
Transmembranei252 – 277HelicalSequence analysisAdd BLAST26
Transmembranei289 – 310HelicalSequence analysisAdd BLAST22
Transmembranei400 – 421HelicalSequence analysisAdd BLAST22
Transmembranei442 – 461HelicalSequence analysisAdd BLAST20
Transmembranei473 – 496HelicalSequence analysisAdd BLAST24
Transmembranei517 – 537HelicalSequence analysisAdd BLAST21
Transmembranei566 – 592HelicalSequence analysisAdd BLAST27

Keywords - Cellular componenti

Membrane

Family & Domainsi

Sequence similaritiesi

Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Family and domain databases

InterProiView protein in InterPro
IPR000175. Na/ntran_symport.
IPR002438. Na/ntran_symport_orphan.
PANTHERiPTHR11616. PTHR11616. 1 hit.
PfamiView protein in Pfam
PF00209. SNF. 1 hit.
PRINTSiPR00176. NANEUSMPORT.
PR01206. ORPHTRNSPORT.
PROSITEiView protein in PROSITE
PS00610. NA_NEUROTRAN_SYMP_1. 1 hit.
PS00754. NA_NEUROTRAN_SYMP_2. 1 hit.
PS50267. NA_NEUROTRAN_SYMP_3. 1 hit.

Sequencei

Sequence statusi: Complete.

E0V8F6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQASGMDPL VDMEDERPKW DNKLQYLLSC IGFAVGLGNI WRFPYLCQTY
60 70 80 90 100
GGGAFLIPYF IALVFEGIPL FYIELAIGQR LRRGSIGVWR TISPYLGGVG
110 120 130 140 150
LGCFSVSFLI SLYYNTVLLW VLWFFLNSFQ HPLPWSTCPL DLNRTGFVQE
160 170 180 190 200
CQGSGTVSYF WYRQTLNITS DINNTGTIQW KLFLCLVACW ATVYLCVIRG
210 220 230 240 250
IESTGKVIYF TALFPYLVLT IFLIRGLTLP GATEGLTYLF TPNMKILQNP
260 270 280 290 300
RVWLDAATQI FFSLSLAFGG HIAFASYNPP RNNCEKDAVT IALVNSMTSL
310 320 330 340 350
YASITIFSIM GFKATNDYGR CLDGNILSLI NEFDFPELSI SRDEYPAVLM
360 370 380 390 400
HLNATHAERL AQLPLKTCHL EDFLDKSASG PGLAFIVFTE AVLHMPAASV
410 420 430 440 450
WSVLFFGMLF TLGLSSMFGN MESVITPLFD MGILPRGIPK EIMTGMVCLV
460 470 480 490 500
CFLSAICFTL QSGNYWLEIF DSFTASLNLI FFAFMEVVGV IYVYGMKRFC
510 520 530 540 550
DDIEWMTGRR PGLYWQVTWR VVSPMLLLSI FLSYIILLTQ RPPSYKAWNP
560 570 580 590 600
QYEHFPSREE KLYPGWVQIV CVLLSFLPSL WVPAVALCHL LYQHRRRWKD
610
AHLESGLKPQ ESRNC
Length:615
Mass (Da):69,799
Last modified:November 2, 2010 - v1
Checksum:i1E3EC5681A8569DD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DP001234 Genomic DNA. Translation: ADN07554.1.

Similar proteinsi

Entry informationi

Entry nameiE0V8F6_MICOH
AccessioniPrimary (citable) accession number: E0V8F6
Entry historyiIntegrated into UniProtKB/TrEMBL: November 2, 2010
Last sequence update: November 2, 2010
Last modified: May 10, 2017
This is version 17 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)