ID   E0U5R9_GLOV7            Unreviewed;       348 AA.
AC   E0U5R9;
DT   02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2010, sequence version 1.
DT   27-MAR-2024, entry version 65.
DE   SubName: Full=Response regulator receiver modulated metal dependent phosphohydrolase {ECO:0000313|EMBL:ADN15910.1};
GN   OrderedLocusNames=Cyan7822_3985 {ECO:0000313|EMBL:ADN15910.1};
OS   Gloeothece verrucosa (strain PCC 7822) (Cyanothece sp. (strain PCC 7822)).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC   Chroococcales; Aphanothecaceae; Gloeothece; Gloeothece verrucosa.
OX   NCBI_TaxID=497965 {ECO:0000313|EMBL:ADN15910.1, ECO:0000313|Proteomes:UP000008206};
RN   [1] {ECO:0000313|Proteomes:UP000008206}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 7822 {ECO:0000313|Proteomes:UP000008206};
RX   PubMed=21972240; DOI=10.1128/mBio.00214-11;
RA   Bandyopadhyay A., Elvitigala T., Welsh E., Stockel J., Liberton M., Min H.,
RA   Sherman L.A., Pakrasi H.B.;
RT   "Novel metabolic attributes of the genus Cyanothece, comprising a group of
RT   unicellular nitrogen-fixing Cyanobacteria.";
RL   MBio 2:E214-E214(2011).
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DR   EMBL; CP002198; ADN15910.1; -; Genomic_DNA.
DR   AlphaFoldDB; E0U5R9; -.
DR   STRING; 497965.Cyan7822_3985; -.
DR   KEGG; cyj:Cyan7822_3985; -.
DR   eggNOG; COG3437; Bacteria.
DR   HOGENOM; CLU_000445_92_10_3; -.
DR   OrthoDB; 9804747at2; -.
DR   Proteomes; UP000008206; Chromosome.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR   CDD; cd00077; HDc; 1.
DR   Gene3D; 3.40.50.2300; -; 1.
DR   Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR037522; HD_GYP_dom.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   PANTHER; PTHR45228:SF1; CYCLIC DI-GMP PHOSPHODIESTERASE TM_0186; 1.
DR   PANTHER; PTHR45228; CYCLIC DI-GMP PHOSPHODIESTERASE TM_0186-RELATED; 1.
DR   Pfam; PF13487; HD_5; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF52172; CheY-like; 1.
DR   SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR   PROSITE; PS51832; HD_GYP; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:ADN15910.1};
KW   Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008206}.
FT   DOMAIN          31..147
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000259|PROSITE:PS50110"
FT   DOMAIN          155..348
FT                   /note="HD-GYP"
FT                   /evidence="ECO:0000259|PROSITE:PS51832"
FT   MOD_RES         80
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ   SEQUENCE   348 AA;  39776 MW;  02380408C59DD6AC CRC64;
     MRVSDLLLPI NKLTQINISA MNAIVNCEPA KILIIDDHTH SRMAVKDLLS LDGYEVIETE
     ENFNIVDNVL KKRPDLILLD VMMPGMEGFE VCQCLKQDER TSAIPIIFMT VAEDHQLRRR
     CAQVGGDDVL TKPIERSLLS SRVKSLIEQK RLYEGLDQIE QVLFAIARAI ENRYPNNGNS
     CARLATLANS FGQYLQLSFS ALQNLRYAAY LHDIGTVSIP DEIMLKKGEL TPEEREIIQQ
     HVLIGEEICQ PLPNRRGVLP IIRHHHERWD GSGYPDGLVA DEIPWLAQIF QILDIYVALT
     SERPHKKIYT PREAIEIITE EAAKGWRNPE LVHHFTNFIY IREPVINN
//