Protein translocase subunit SecA - Bacillus subtilis subsp. spizizenii (strain ATCC 23059 / NRRL B-14472 / W23)

Contribute

Send feedback

Read comments (?) or add your own

E0U490 (E0U490_BACPZ) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 23. History...

Clusters with 100%, 90%, 50% identity |

Third-party data

text xml rdf/xml gff fasta

Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info Customize order

Names and origin

Protein names

Recommended name:
Protein translocase subunit SecA HAMAP-Rule MF_01382 RuleBase RU003874

Gene names

Name:	secA HAMAP-Rule MF_01382 EMBL ADM39495.1
Ordered Locus Names:	BSUW23_17300 EMBL ADM39495.1

Organism

Bacillus subtilis subsp. spizizenii (strain ATCC 23059 / NRRL B-14472 / W23) [Complete proteome] [HAMAP] EMBL ADM39495.1

Taxonomic identifier

655816 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus ›

Protein attributes

Sequence length	841 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane By similarity. HAMAP-Rule MF_01382
Cofactor	May bind 1 zinc ion per subunit By similarity. HAMAP-Rule MF_01382
Subunit structure	Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved By similarity. HAMAP-Rule MF_01382
Subcellular location	Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note: Distribution is 50-50 By similarity. HAMAP-Rule MF_01382
Sequence similarities	Belongs to the SecA family. HAMAP-Rule MF_01382 RuleBase RU003874

Ontologies

Keywords
Biological process	Protein transport Translocation SAAS SAAS004027 HAMAP-Rule MF_01382 RuleBase RU003874 Transport
Cellular component	Cell membrane HAMAP-Rule MF_01382 SAAS SAAS004027 Cytoplasm HAMAP-Rule MF_01382 SAAS SAAS004027 Membrane
Ligand	ATP-binding HAMAP-Rule MF_01382 RuleBase RU003874 SAAS SAAS004027 Metal-binding HAMAP-Rule MF_01382 SAAS SAAS004027 Nucleotide-binding Zinc HAMAP-Rule MF_01382 SAAS SAAS004027
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	intracellular protein transmembrane transport Inferred from electronic annotation. Source: HAMAP protein import Inferred from electronic annotation. Source: InterPro protein targeting Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: HAMAP helicase activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW nucleic acid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Regions

Nucleotide binding

100 – 107

ATP By similarity HAMAP-Rule MF_01382

Sites

Metal binding

825

Zinc By similarity HAMAP-Rule MF_01382

Metal binding

827

Zinc By similarity HAMAP-Rule MF_01382

Metal binding

836

Zinc By similarity HAMAP-Rule MF_01382

Metal binding

837

Zinc By similarity HAMAP-Rule MF_01382

Sequences

Sequence

Length

Mass (Da)

Tools

E0U490 [UniParc].

Last modified November 2, 2010. Version 1.
Checksum: 62647C2588EC83A2
Show »

FASTA

841

95,574

        10         20         30         40         50         60 
MLGILNKMFD PTKRTLNRYE RIANDIDAVR GDYENLSDDA LKHKTIEFKE RLEKGATTDD 

        70         80         90        100        110        120 
LLVEAFAVVR EASRRVTGMF PFKVQLMGGV ALHDGNIAEM KTGEGKTLTS TLPVYLNALT 

       130        140        150        160        170        180 
GKGVHIVTVN EYLASRDAEQ MGKIFEFLGM TVGLNLNSMS KDEKREAYAA DITYSTNNEL 

       190        200        210        220        230        240 
GFDYLRDNMV LYKEQMVQRP LHFAVIDEVD SILIDEARTP LIISGQAAKS TKLYVQANAF 

       250        260        270        280        290        300 
VRTLKAEKDY TYDIKTKGVQ LTEEGMTKAE KAFGIDNLFD VKHVALNHHI NQSLKAHAAM 

       310        320        330        340        350        360 
QKDVDYVVED GQVVIVDSFT GRLMKGRRYS EGLHQAIEAK EGLEIQNESM TLATITFQNY 

       370        380        390        400        410        420 
FRMYEKLAGM TGTAKTEEEE FRNIYNMQVV TIPTNKPVVR DDRPDLIYRT MEGKFKAVAE 

       430        440        450        460        470        480 
DVAQRYMTGQ PVLVGTVAVE TSELISKLLK NKGIPHQVLN AKNHEREAQI IEEAGQKGAV 

       490        500        510        520        530        540 
TIATNMAGRG TDIKLGEGVK ELGGLAVVGT ERHESRRIDN QLRGRSGRQG DPGITQFYLS 

       550        560        570        580        590        600 
MEDELMRRFG AERTMAMLDR FGMDDSTPIQ SKMVSRAVES SQKRVEGNNF DSRKQLLQYD 

       610        620        630        640        650        660 
DVLRQQREVI YKQRFEVIDS ENLREIVENM IKSSLERAIA AYTPREELPE EWKLDGLVEL 

       670        680        690        700        710        720 
VNTTYLDEGA LEKSDIFGKE PDEMHELIMD RIMTKYNEKE VKFGEEQMRE FEKVIVLRAV 

       730        740        750        760        770        780 
DSKWMDHIDA MDQLRQGIHL RAYAQTNPLR EYQMEGFTMF ENMIESIEDE VAKFVMKAEI 

       790        800        810        820        830        840 
ENNLEREEVV QGQTTAHQQQ EGDDNKKAKK APVRKVVDIG RNAPCHCGSG KKYKNCCGRT 


E

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete genome sequence of Bacillus subtilis subsp. spizizenii str. W23." Zeigler D.R. Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 23059 / NRRL B-14472 / W23.
[2]	Zeigler D.R. Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: W23.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002183 Genomic DNA. Translation: ADM39495.1.
RefSeq	YP_003867804.1. NC_014479.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADM39495; ADM39495; BSUW23_17300.
GeneID	9724468.
KEGG	bss:BSUW23_17300.
PATRIC	42193173. VBIBacSub57968_3533.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000218169.
KO	K03070.
OMA	ERFFILQ.
Enzyme and pathway databases
BioCyc	BSUB655816:GCOR-3538-MONOMER.
Family and domain databases
Gene3D	1.10.3060.10. 1 hit. 3.90.1440.10. 1 hit.
HAMAP	MF_01382. SecA.
InterPro	IPR001650. Helicase_C. IPR027417. P-loop_NTPase. IPR004027. SEC_C_motif. IPR000185. SecA. IPR020937. SecA_CS. IPR011115. SecA_DEAD. IPR014018. SecA_motor_DEAD. IPR011130. SecA_preprotein_X-link_dom. IPR011116. SecA_Wing/Scaffold. [Graphical view]
Pfam	PF00271. Helicase_C. 1 hit. PF02810. SEC-C. 1 hit. PF07517. SecA_DEAD. 1 hit. PF01043. SecA_PP_bind. 1 hit. PF07516. SecA_SW. 1 hit. [Graphical view]
PRINTS	PR00906. SECA.
SMART	SM00957. SecA_DEAD. 1 hit. SM00958. SecA_PP_bind. 1 hit. [Graphical view]
SUPFAM	SSF81767. SecA_PP_bd. 1 hit. SSF81886. SecA_SW. 1 hit. SSF52540. SSF52540. 2 hits.
TIGRFAMs	TIGR00963. secA. 1 hit.
PROSITE	PS01312. SECA. 1 hit. PS51196. SECA_MOTOR_DEAD. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

E0U490_BACPZ

Accession

Primary (citable) accession number: E0U490

Entry history

Integrated into UniProtKB/TrEMBL:	November 2, 2010
Last sequence update:	November 2, 2010
Last modified:	May 29, 2013
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Regions

Sites

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

Entry information